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The map label for this gene is speD

Identifier: 21672488

GI number: 21672488

Start: 230163

End: 230969

Strand: Reverse

Name: speD

Synonym: BUsg202

Alternate gene names: 21672488

Gene position: 230969-230163 (Counterclockwise)

Preceding gene: 21672489

Following gene: 21672483

Centisome position: 36.01

GC content: 24.78

Gene sequence:

>807_bases
TTGCAAAAACTAAAATTATATGGCTTTAATAATTTAACTAAAAGCCTAAGTTTTTGTATTTATGATATTTGTTATGCGAA
TACTAATGATTCAAGAAATAGTTATATTTCTTATATTGATGAACAATATAATGCTATTCGACTAACAAAAATCTTAAAAA
AAACCTGTTCAATTATTGGTGCTAACGTTCTTAACGTTTTTCATCAAGATTATGAACCTCAAGGTGCCAGCGTAACTATT
TTAGTATGCGAAGAACCAATAAATTTAGAAAAAGTAAATATTGTAAATAAAAGTAATAAAATTATATCATCTTCTGTATT
AGCTCATTTAGATAAAAGTCATATTTGTGTTCATACATACCCAGAAAGTCATCCTCAAAGTGGAATTTGTACCTTTCGCG
CAGATATAGAAGTTTCAACATGTGGGATAATCTCTCCTCTTAATGCATTAAATTATCTTATTCATCAACTAGAATCAGAT
ATTGTAACAATTGAATATCGTGTTAGAGGATTCACGCGCGATATTCATGGTATAAAACATTTTATTGATCATAAGATTAA
TTCTATTCAGAATTTTATGTCTCATGATATAAAATCAATGTATGAAATGTTTGATGTTAATATATATCAAGAAAACATTT
TTCATACTCGTATGTTACTAAAAGAATTTAATTTAAAAAACTATTTATTTAATATTAACGTAAAAGATTTATCAAAAAAA
GAACACTCTTATATTATAGACTTGTTATGGAAAGAAATGAGAGAAATATATCATGGTAAAAATATCTCTATGATTAAAAA
AATATAA

Upstream 100 bases:

>100_bases
CTATAATTCCAATATTCATATAAGCAGTTTTTATTTACCTCAATATATAATTAATACATTAGATAAAAGTTAAAAATCCT
GATATAGGAGAGTAATTAAA

Downstream 100 bases:

>100_bases
CTTTTGAACTTATATTTTTTATAATGTATTCAAAAGTTAAAAAATTGATACACTTCTTTTACACCAAGAAAAGAAGTGTA
TCAATTGTTAATTTAACAAC

Product: S-adenosylmethionine decarboxylase

Products: NA

Alternate protein names: AdoMetDC; SAMDC

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MQKLKLYGFNNLTKSLSFCIYDICYANTNDSRNSYISYIDEQYNAIRLTKILKKTCSIIGANVLNVFHQDYEPQGASVTI
LVCEEPINLEKVNIVNKSNKIISSSVLAHLDKSHICVHTYPESHPQSGICTFRADIEVSTCGIISPLNALNYLIHQLESD
IVTIEYRVRGFTRDIHGIKHFIDHKINSIQNFMSHDIKSMYEMFDVNIYQENIFHTRMLLKEFNLKNYLFNINVKDLSKK
EHSYIIDLLWKEMREIYHGKNISMIKKI

Sequences:

>Translated_268_residues
MQKLKLYGFNNLTKSLSFCIYDICYANTNDSRNSYISYIDEQYNAIRLTKILKKTCSIIGANVLNVFHQDYEPQGASVTI
LVCEEPINLEKVNIVNKSNKIISSSVLAHLDKSHICVHTYPESHPQSGICTFRADIEVSTCGIISPLNALNYLIHQLESD
IVTIEYRVRGFTRDIHGIKHFIDHKINSIQNFMSHDIKSMYEMFDVNIYQENIFHTRMLLKEFNLKNYLFNINVKDLSKK
EHSYIIDLLWKEMREIYHGKNISMIKKI
>Mature_268_residues
MQKLKLYGFNNLTKSLSFCIYDICYANTNDSRNSYISYIDEQYNAIRLTKILKKTCSIIGANVLNVFHQDYEPQGASVTI
LVCEEPINLEKVNIVNKSNKIISSSVLAHLDKSHICVHTYPESHPQSGICTFRADIEVSTCGIISPLNALNYLIHQLESD
IVTIEYRVRGFTRDIHGIKHFIDHKINSIQNFMSHDIKSMYEMFDVNIYQENIFHTRMLLKEFNLKNYLFNINVKDLSKK
EHSYIIDLLWKEMREIYHGKNISMIKKI

Specific function: Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine

COG id: COG1586

COG function: function code E; S-adenosylmethionine decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic AdoMetDC family. Type 2 subfamily

Homologues:

Organism=Escherichia coli, GI1786311, Length=265, Percent_Identity=70.188679245283, Blast_Score=404, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPED_BUCAP (Q8K9T6)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660555.1
- ProteinModelPortal:   Q8K9T6
- EnsemblBacteria:   EBBUCT00000000178
- GeneID:   1005399
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg202
- GeneTree:   EBGT00050000008111
- HOGENOM:   HBG303125
- OMA:   YNAERLT
- ProtClustDB:   PRK05462
- BioCyc:   BAPH198804:BUSG202-MONOMER
- HAMAP:   MF_00465
- InterPro:   IPR003826
- InterPro:   IPR009165
- InterPro:   IPR016067
- Gene3D:   G3DSA:3.60.90.10
- PIRSF:   PIRSF001356
- TIGRFAMs:   TIGR03331

Pfam domain/function: PF02675 AdoMet_dc; SSF56276 S-AdenosylMet_decarbase_core

EC number: =4.1.1.50

Molecular weight: Translated: 31253; Mature: 31253

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: NA

Important sites: ACT_SITE 113-113 ACT_SITE 118-118 ACT_SITE 141-141

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKLKLYGFNNLTKSLSFCIYDICYANTNDSRNSYISYIDEQYNAIRLTKILKKTCSIIG
CCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANVLNVFHQDYEPQGASVTILVCEEPINLEKVNIVNKSNKIISSSVLAHLDKSHICVHTY
HHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEC
PESHPQSGICTFRADIEVSTCGIISPLNALNYLIHQLESDIVTIEYRVRGFTRDIHGIKH
CCCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHH
FIDHKINSIQNFMSHDIKSMYEMFDVNIYQENIFHTRMLLKEFNLKNYLFNINVKDLSKK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCH
EHSYIIDLLWKEMREIYHGKNISMIKKI
HHHHHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure
MQKLKLYGFNNLTKSLSFCIYDICYANTNDSRNSYISYIDEQYNAIRLTKILKKTCSIIG
CCCEEEECCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ANVLNVFHQDYEPQGASVTILVCEEPINLEKVNIVNKSNKIISSSVLAHLDKSHICVHTY
HHHHHHHHHCCCCCCCEEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHCCCCCEEEEEC
PESHPQSGICTFRADIEVSTCGIISPLNALNYLIHQLESDIVTIEYRVRGFTRDIHGIKH
CCCCCCCCEEEEEECCEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEECHHHHHHHHHHH
FIDHKINSIQNFMSHDIKSMYEMFDVNIYQENIFHTRMLLKEFNLKNYLFNINVKDLSKK
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHCCH
EHSYIIDLLWKEMREIYHGKNISMIKKI
HHHHHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438