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The map label for this gene is dapB

Identifier: 21672429

GI number: 21672429

Start: 155046

End: 155867

Strand: Reverse

Name: dapB

Synonym: BUsg139

Alternate gene names: 21672429

Gene position: 155867-155046 (Counterclockwise)

Preceding gene: 21672430

Following gene: 21672428

Centisome position: 24.3

GC content: 25.79

Gene sequence:

>822_bases
ATGAAAAAAAAAATAACTCGTATCGCAATTACTGGTGCTATGGGACGTATGGGCCAGGTATTAATTAAAGAAATACAAAA
AAATAAAAATACTGTTTTAACAGCGGCATTAGTAAAAAATAATCATCCCTTGATTGGTCAAAATATAGGAGAAAAAATCG
GAATAGGTAAAACAAGCGTATCTATTAGTAGTGATATAAATATAGAAAAAAATGATTTTGACGTTTTAATCGACTTTACA
AAACCAAGTGGTACGTTTTATTTTTTAGAACAATGCTATGAATTTAAAAAAAATATGATTATAGGAACCACTGGTTTTTC
AGAGAAAGAAATTAAAACTATAAATTCATATGCTAAAAAAATTGCTTTAATTAAAGCATCAAATTTTAGTATTGGGATTA
ACTTATTATATCAATTAATTCAAAAAACTACTAAAATTTTAGGAAATACTTCAGATATTGATATTATAGAATATCATCAC
CGTAATAAAATAGATATACCTTCAGGAACAGCACTCAGTATTGGAGAAAATATATCAAAAGTCATGAACTGGGAATTAAA
TAAACACTCTTTGTATTATACAAAAGGTATAACAAAAAAAATCAGAGAAACAAAAAAAATTGGTTTTTCTAGTATAAGAT
CAGGAAATATTATTGGTAAACATACTGTTTTATTCTCAAGCTCTGATGAAGAAATTAAAATTACTCATAGTGCTTTTAAT
AGAGAGTCTTTTGCTAAAGGTGCTATTGAAGCAGCTGTATGGATTCACGAAAAAAAACACGGATTATTTAATATGAACGA
TATATTAAAAGATAAATTTTAA

Upstream 100 bases:

>100_bases
AGGTTTTAAAAATCCACCAAAAGAAATGTTAGGAGATGAAGAAAAAACAATTTTTAAAATACCCAAAAATTTAAACGTAC
AAAATTAGAAAAATACAATT

Downstream 100 bases:

>100_bases
AGTATGCATATTAAAAAAATTTATAAAAATATAAATATTTACTACGATAATAGACAAAAATATTAAATTTAGTTAAAATA
ATATGCAATTTTTCATATTT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MKKKITRIAITGAMGRMGQVLIKEIQKNKNTVLTAALVKNNHPLIGQNIGEKIGIGKTSVSISSDINIEKNDFDVLIDFT
KPSGTFYFLEQCYEFKKNMIIGTTGFSEKEIKTINSYAKKIALIKASNFSIGINLLYQLIQKTTKILGNTSDIDIIEYHH
RNKIDIPSGTALSIGENISKVMNWELNKHSLYYTKGITKKIRETKKIGFSSIRSGNIIGKHTVLFSSSDEEIKITHSAFN
RESFAKGAIEAAVWIHEKKHGLFNMNDILKDKF

Sequences:

>Translated_273_residues
MKKKITRIAITGAMGRMGQVLIKEIQKNKNTVLTAALVKNNHPLIGQNIGEKIGIGKTSVSISSDINIEKNDFDVLIDFT
KPSGTFYFLEQCYEFKKNMIIGTTGFSEKEIKTINSYAKKIALIKASNFSIGINLLYQLIQKTTKILGNTSDIDIIEYHH
RNKIDIPSGTALSIGENISKVMNWELNKHSLYYTKGITKKIRETKKIGFSSIRSGNIIGKHTVLFSSSDEEIKITHSAFN
RESFAKGAIEAAVWIHEKKHGLFNMNDILKDKF
>Mature_273_residues
MKKKITRIAITGAMGRMGQVLIKEIQKNKNTVLTAALVKNNHPLIGQNIGEKIGIGKTSVSISSDINIEKNDFDVLIDFT
KPSGTFYFLEQCYEFKKNMIIGTTGFSEKEIKTINSYAKKIALIKASNFSIGINLLYQLIQKTTKILGNTSDIDIIEYHH
RNKIDIPSGTALSIGENISKVMNWELNKHSLYYTKGITKKIRETKKIGFSSIRSGNIIGKHTVLFSSSDEEIKITHSAFN
RESFAKGAIEAAVWIHEKKHGLFNMNDILKDKF

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=263, Percent_Identity=43.7262357414449, Blast_Score=240, Evalue=8e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_BUCAP (Q8K9Z5)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660496.1
- ProteinModelPortal:   Q8K9Z5
- SMR:   Q8K9Z5
- EnsemblBacteria:   EBBUCT00000000066
- GeneID:   1005956
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg139
- GeneTree:   EBGT00050000007836
- HOGENOM:   HBG594002
- OMA:   GRMGKTL
- ProtClustDB:   PRK00048
- BioCyc:   BAPH198804:BUSG139-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 30674; Mature: 30674

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKKITRIAITGAMGRMGQVLIKEIQKNKNTVLTAALVKNNHPLIGQNIGEKIGIGKTSV
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEE
SISSDINIEKNDFDVLIDFTKPSGTFYFLEQCYEFKKNMIIGTTGFSEKEIKTINSYAKK
EECCCCCEECCCEEEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHH
IALIKASNFSIGINLLYQLIQKTTKILGNTSDIDIIEYHHRNKIDIPSGTALSIGENISK
EEEEEECCCEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHH
VMNWELNKHSLYYTKGITKKIRETKKIGFSSIRSGNIIGKHTVLFSSSDEEIKITHSAFN
HHCCCCCCCEEEEEHHHHHHHHHHHHCCHHHCCCCCEEEEEEEEEECCCCEEEEEEHHCC
RESFAKGAIEAAVWIHEKKHGLFNMNDILKDKF
HHHHHHHHHHHEEEEEECCCCCCCHHHHHHCCC
>Mature Secondary Structure
MKKKITRIAITGAMGRMGQVLIKEIQKNKNTVLTAALVKNNHPLIGQNIGEKIGIGKTSV
CCCCEEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCEE
SISSDINIEKNDFDVLIDFTKPSGTFYFLEQCYEFKKNMIIGTTGFSEKEIKTINSYAKK
EECCCCCEECCCEEEEEEEECCCCCCHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHH
IALIKASNFSIGINLLYQLIQKTTKILGNTSDIDIIEYHHRNKIDIPSGTALSIGENISK
EEEEEECCCEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCEEEHHHHHHH
VMNWELNKHSLYYTKGITKKIRETKKIGFSSIRSGNIIGKHTVLFSSSDEEIKITHSAFN
HHCCCCCCCEEEEEHHHHHHHHHHHHCCHHHCCCCCEEEEEEEEEECCCCEEEEEEHHCC
RESFAKGAIEAAVWIHEKKHGLFNMNDILKDKF
HHHHHHHHHHHEEEEEECCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438