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The map label for this gene is ribB

Identifier: 21672349

GI number: 21672349

Start: 64337

End: 64978

Strand: Reverse

Name: ribB

Synonym: BUsg056

Alternate gene names: 21672349

Gene position: 64978-64337 (Counterclockwise)

Preceding gene: 21672350

Following gene: 21672347

Centisome position: 10.13

GC content: 32.24

Gene sequence:

>642_bases
ATGAATCAAACACTGCTTTCTGAATTTGGAAACCCTATAGAACGAGTTAAAAAAGCTATATCTGCTTTACAATTAGGTGA
GGGGATTATTATATTAGATGATGAAAAACGTGAAAATGAGGGAGATCTTGTTTTTTCATCTGAAACAATGACAGTCGAAC
AGATGGCTTTAACAATTAGATATGGTAGTGGTATAGTATGTTTATGTATAACAGAATCTAAACGTAAAAAATTAAACTTA
CCTATGATGGTTAAACATAATACTAGTACTTATCGTACTGGATTTACAGTAACAATAGAAGCCTCAAAAGGTGTTTCCAC
TGGTGTATCAGCGAAAGATCGATTAACTACTATAAAAACTGCTACAGCAGATGATGCTCAACCTAGTGACTTAAATAGAC
CAGGACATGTATTTCCTCTTAGAGCAAATGGAGGCGGGATTTTAGCACGAGCAGGACATACAGAAGCAGCTATCGAAATA
GTATCGCTTGCAGGTTTTAAACCATATGGAGTAATTTGTGAACTAACAAACAAAGATGGATCAATGTCTCGAACACCTGA
AATTATAAAATTTTCAAAATCTAAAAAAATGAAAATATTAACTATTAAAGACTTAATTCTCTATGTTCAAAATAAAAAAT
AA

Upstream 100 bases:

>100_bases
TTTTATTCGATATATAATAAAATAATTTACAATATTTAATTTAATATTATTCAATTTTCAAGAATTTTTATTTGTTTAAT
AATTTAAGAAGGTTTTCAAA

Downstream 100 bases:

>100_bases
AAAATTTTATAAAAAAAAGAAATTGTTAAACACTAATATTTATTAAATATAAGATAACTTATCTATAGACCATTTTGGTT
TCACAATTATCTCCAATTGA

Product: 3,4-dihydroxy-2-butanone 4-phosphate synthase

Products: NA

Alternate protein names: DHBP synthase

Number of amino acids: Translated: 213; Mature: 213

Protein sequence:

>213_residues
MNQTLLSEFGNPIERVKKAISALQLGEGIIILDDEKRENEGDLVFSSETMTVEQMALTIRYGSGIVCLCITESKRKKLNL
PMMVKHNTSTYRTGFTVTIEASKGVSTGVSAKDRLTTIKTATADDAQPSDLNRPGHVFPLRANGGGILARAGHTEAAIEI
VSLAGFKPYGVICELTNKDGSMSRTPEIIKFSKSKKMKILTIKDLILYVQNKK

Sequences:

>Translated_213_residues
MNQTLLSEFGNPIERVKKAISALQLGEGIIILDDEKRENEGDLVFSSETMTVEQMALTIRYGSGIVCLCITESKRKKLNL
PMMVKHNTSTYRTGFTVTIEASKGVSTGVSAKDRLTTIKTATADDAQPSDLNRPGHVFPLRANGGGILARAGHTEAAIEI
VSLAGFKPYGVICELTNKDGSMSRTPEIIKFSKSKKMKILTIKDLILYVQNKK
>Mature_213_residues
MNQTLLSEFGNPIERVKKAISALQLGEGIIILDDEKRENEGDLVFSSETMTVEQMALTIRYGSGIVCLCITESKRKKLNL
PMMVKHNTSTYRTGFTVTIEASKGVSTGVSAKDRLTTIKTATADDAQPSDLNRPGHVFPLRANGGGILARAGHTEAAIEI
VSLAGFKPYGVICELTNKDGSMSRTPEIIKFSKSKKMKILTIKDLILYVQNKK

Specific function: Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate

COG id: COG0108

COG function: function code H; 3,4-dihydroxy-2-butanone 4-phosphate synthase

Gene ontology:

Cell location: Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHBP synthase family

Homologues:

Organism=Escherichia coli, GI1789420, Length=210, Percent_Identity=67.6190476190476, Blast_Score=320, Evalue=5e-89,
Organism=Saccharomyces cerevisiae, GI6320695, Length=203, Percent_Identity=35.4679802955665, Blast_Score=150, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIBB_BUCAP (Q8KA55)

Other databases:

- EMBL:   AE013218
- RefSeq:   NP_660416.1
- ProteinModelPortal:   Q8KA55
- SMR:   Q8KA55
- EnsemblBacteria:   EBBUCT00000000258
- GeneID:   1005872
- GenomeReviews:   AE013218_GR
- KEGG:   bas:BUsg056
- GeneTree:   EBGT00050000007959
- HOGENOM:   HBG735778
- OMA:   RGHTEAT
- ProtClustDB:   PRK03353
- BioCyc:   BAPH198804:BUSG056-MONOMER
- HAMAP:   MF_00180
- InterPro:   IPR017945
- InterPro:   IPR000422
- Gene3D:   G3DSA:3.90.870.10
- TIGRFAMs:   TIGR00506

Pfam domain/function: PF00926 DHBP_synthase; SSF55821 DHBP_synth_RibB-like_a/b_dom

EC number: =4.1.99.12

Molecular weight: Translated: 23278; Mature: 23278

Theoretical pI: Translated: 9.81; Mature: 9.81

Prosite motif: NA

Important sites: BINDING 42-42 BINDING 174-174

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQTLLSEFGNPIERVKKAISALQLGEGIIILDDEKRENEGDLVFSSETMTVEQMALTIR
CCCCHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCEEEEEEEEEEE
YGSGIVCLCITESKRKKLNLPMMVKHNTSTYRTGFTVTIEASKGVSTGVSAKDRLTTIKT
ECCCEEEEEEECCCHHCCCCCEEEEECCCEEECCEEEEEECCCCCCCCCCCCCCEEEEEE
ATADDAQPSDLNRPGHVFPLRANGGGILARAGHTEAAIEIVSLAGFKPYGVICELTNKDG
CCCCCCCCCCCCCCCCEEEEEECCCEEEEECCCCHHHEEEEECCCCCCCEEEEEEECCCC
SMSRTPEIIKFSKSKKMKILTIKDLILYVQNKK
CCCCCCCEEEECCCCCEEEEEEEEEEEEEECCC
>Mature Secondary Structure
MNQTLLSEFGNPIERVKKAISALQLGEGIIILDDEKRENEGDLVFSSETMTVEQMALTIR
CCCCHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCEEEEEEEEEEE
YGSGIVCLCITESKRKKLNLPMMVKHNTSTYRTGFTVTIEASKGVSTGVSAKDRLTTIKT
ECCCEEEEEEECCCHHCCCCCEEEEECCCEEECCEEEEEECCCCCCCCCCCCCCEEEEEE
ATADDAQPSDLNRPGHVFPLRANGGGILARAGHTEAAIEIVSLAGFKPYGVICELTNKDG
CCCCCCCCCCCCCCCCEEEEEECCCEEEEECCCCHHHEEEEECCCCCCCEEEEEEECCCC
SMSRTPEIIKFSKSKKMKILTIKDLILYVQNKK
CCCCCCCEEEECCCCCEEEEEEEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12089438