Click here to switch to the map view.

The map label for this gene is frr

Identifier: 30263828

GI number: 30263828

Start: 3639736

End: 3640293

Strand: Reverse

Name: frr

Synonym: BA_3962

Alternate gene names: 30263828

Gene position: 3640293-3639736 (Counterclockwise)

Preceding gene: 30263829

Following gene: 30263827

Centisome position: 69.64

GC content: 36.2

Gene sequence:

>558_bases
ATGGGACAACAAGTATTAAAGTTTTCAAATGAAAAAATGGAAAAAGCAGTTGCTGCTTATTCTCGTGAATTAGCAACAGT
TCGTGCTGGCCGTGCAAGCGCGTCTGTATTAGATAAAGTACAAGTTGATTACTATGGTGCACCAACACCAGTTGTGCAAT
TAGCGAACATTACAGTTCCAGAAGCACGTTTACTTGTAATTCAACCTTATGATAAAACTTCTATCGGTGATATCGAAAAA
GCAATTTTAAAAGCAGATTTAGGCTTAAACCCTTCTAATGACGGAACTGTAATTCGTATTGCATTCCCTGCATTAACAGA
AGAGCGTCGTCGTGATCTTGTAAAAGTTGTGAAAAAATATGCTGAAGAAGCAAAAGTTGCTGTTCGTAACGTACGTCGTG
ACGGTAACGACGATCTTAAAAAGCTTGAAAAAGCTGGCGAGATTACAGAAGATGATTTAAGAGGATATACTGAAGATATC
CAAAAAGAAACAGATAAATATATTGCAAAAGTTGACGAAATCGCAAAAAACAAAGAAAAAGAAATCATGGAAGTGTAA

Upstream 100 bases:

>100_bases
ATGATATTCCATTAATTGTATTCTCAGTTATGGAAAAAGGTAATATTAAACGTGCCGTTTTAGGTGAAAATATCGGAACA
GTTGTAAGGGGGAAATAAAT

Downstream 100 bases:

>100_bases
TAGCGATACCTTCGCAAATATGACCCTCTTCTTAAGGGGGTCTTTTTACACTTTTAGGCATACGTCTGCTTGCTGGAGGG
TATGAATGATGTTTAAAAAC

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MGQQVLKFSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEK
AILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDI
QKETDKYIAKVDEIAKNKEKEIMEV

Sequences:

>Translated_185_residues
MGQQVLKFSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEK
AILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDI
QKETDKYIAKVDEIAKNKEKEIMEV
>Mature_184_residues
GQQVLKFSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVPEARLLVIQPYDKTSIGDIEKA
ILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQ
KETDKYIAKVDEIAKNKEKEIMEV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=176, Percent_Identity=28.4090909090909, Blast_Score=69, Evalue=2e-12,
Organism=Homo sapiens, GI291042689, Length=171, Percent_Identity=29.8245614035088, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1786368, Length=184, Percent_Identity=47.8260869565217, Blast_Score=174, Evalue=3e-45,
Organism=Drosophila melanogaster, GI24661488, Length=183, Percent_Identity=26.2295081967213, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_BACAA (C3P5M6)

Other databases:

- EMBL:   CP001598
- RefSeq:   YP_002868062.1
- ProteinModelPortal:   C3P5M6
- SMR:   C3P5M6
- EnsemblBacteria:   EBBACT00000126544
- GeneID:   7852855
- GenomeReviews:   CP001598_GR
- KEGG:   bai:BAA_3985
- GeneTree:   EBGT00050000002922
- ProtClustDB:   PRK00083
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 20680; Mature: 20549

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGQQVLKFSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
EARLLVIQPYDKTSIGDIEKAILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
AEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQKETDKYIAKVDEIAKNKEK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
EIMEV
HHHCC
>Mature Secondary Structure 
GQQVLKFSNEKMEKAVAAYSRELATVRAGRASASVLDKVQVDYYGAPTPVVQLANITVP
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
EARLLVIQPYDKTSIGDIEKAILKADLGLNPSNDGTVIRIAFPALTEERRRDLVKVVKKY
CCEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHH
AEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDIQKETDKYIAKVDEIAKNKEK
HHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHH
EIMEV
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA