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The map label for this gene is sirA [H]

Identifier: 30263627

GI number: 30263627

Start: 3443118

End: 3443558

Strand: Reverse

Name: sirA [H]

Synonym: BA_3743

Alternate gene names: 30263627

Gene position: 3443558-3443118 (Counterclockwise)

Preceding gene: 30263628

Following gene: 30263626

Centisome position: 65.88

GC content: 33.33

Gene sequence:

>441_bases
ATGAAAACGTATGAATTGTATTTAATTCAAGAGGATATTGCGAAAGCTTACTTTGGTCGTGAATATTTGTTTTTTGATTT
ATTTGCTCGATTTTCAGAATCTGGGTCCCTTTCGGAGAAAAAAGTGTTATATAAACAAATGATGTATATAACGATGCCAT
TACAAGTAATGAAAATTCATCATAAATTAGAACAAGCTTTGCGCGTTCTTGGTAAATATGATCGAACACATCATACACAT
ACACTTTATACAGGAGCGGAATACGGCGAAATAATGGTGAAACCACACTATATTCGCATGAATACCTCTGGAAATGTTTC
TATGGAAACGACTTTTTTTGAGGTGCTACGGAAGTGTGAATTAACATTTTTAGCTATGGATTATGAAAATACAAAGTACG
GATGGCTGAATCCTCTAAAACAAGTACGAACATATGTGTAA

Upstream 100 bases:

>100_bases
TCGACAGAAAAAGTTTTTTCTCTCTCCGCAGTCAGACAATCATTGCAAAATTTCTTCTATATAATGAAGAGAAAAGGTTG
TCCAGATTGGGAGGCGAAAG

Downstream 100 bases:

>100_bases
AAAATGTCGAATTGTATCTTGTCTTATTGAAAAGGTTTTAGTACACTGTAAGGTAGACAACATGAAGGAGGAAAATATAT
GCCAATTTGGTTAGGTATTC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MKTYELYLIQEDIAKAYFGREYLFFDLFARFSESGSLSEKKVLYKQMMYITMPLQVMKIHHKLEQALRVLGKYDRTHHTH
TLYTGAEYGEIMVKPHYIRMNTSGNVSMETTFFEVLRKCELTFLAMDYENTKYGWLNPLKQVRTYV

Sequences:

>Translated_146_residues
MKTYELYLIQEDIAKAYFGREYLFFDLFARFSESGSLSEKKVLYKQMMYITMPLQVMKIHHKLEQALRVLGKYDRTHHTH
TLYTGAEYGEIMVKPHYIRMNTSGNVSMETTFFEVLRKCELTFLAMDYENTKYGWLNPLKQVRTYV
>Mature_146_residues
MKTYELYLIQEDIAKAYFGREYLFFDLFARFSESGSLSEKKVLYKQMMYITMPLQVMKIHHKLEQALRVLGKYDRTHHTH
TLYTGAEYGEIMVKPHYIRMNTSGNVSMETTFFEVLRKCELTFLAMDYENTKYGWLNPLKQVRTYV

Specific function: Inhibits DNA replication in growing cells, thus reducing chromosome copy number and playing a significant role during the onset of sporulation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019683 [H]

Pfam domain/function: PF10747 DUF2522 [H]

EC number: NA

Molecular weight: Translated: 17484; Mature: 17484

Theoretical pI: Translated: 9.11; Mature: 9.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYELYLIQEDIAKAYFGREYLFFDLFARFSESGSLSEKKVLYKQMMYITMPLQVMKIH
CCEEEEEEEHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HKLEQALRVLGKYDRTHHTHTLYTGAEYGEIMVKPHYIRMNTSGNVSMETTFFEVLRKCE
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCEEEEECCCCCEEEHHHHHHHHHHCC
LTFLAMDYENTKYGWLNPLKQVRTYV
EEEEEEECCCCCCCCCCHHHHHHCCC
>Mature Secondary Structure
MKTYELYLIQEDIAKAYFGREYLFFDLFARFSESGSLSEKKVLYKQMMYITMPLQVMKIH
CCEEEEEEEHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
HKLEQALRVLGKYDRTHHTHTLYTGAEYGEIMVKPHYIRMNTSGNVSMETTFFEVLRKCE
HHHHHHHHHHHHCCCCCCCEEEEECCCCCEEEECCEEEEECCCCCEEEHHHHHHHHHHCC
LTFLAMDYENTKYGWLNPLKQVRTYV
EEEEEEECCCCCCCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9068642; 8969507; 9384377 [H]