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The map label for this gene is ntdC [H]

Identifier: 30263197

GI number: 30263197

Start: 3016690

End: 3017739

Strand: Reverse

Name: ntdC [H]

Synonym: BA_3280

Alternate gene names: 30263197

Gene position: 3017739-3016690 (Counterclockwise)

Preceding gene: 30263198

Following gene: 30263196

Centisome position: 57.73

GC content: 32.76

Gene sequence:

>1050_bases
ATGAATATTGGAATTATAGGTGCAGGAAGTATTGCAAGAGCTCATTCTAGAGCATTATCAACTATTGATAATTGTAAATT
AGTTGGAGTGTATGATGTTAATTCTGAGAATGCCGATAAATTGGTAGGGGATTTTGGTGGGAAGGTTTTTGATAGCTATG
AAGAGTTACTAGAAGTAGTTGATGGGGTAATAATATCTTCCCCGAATTTTTGTCATAAATCTCAAGCTGTTCAAGCATTA
TTAACAAACAAACATGTGTTATGTGAAAAGCCTATGGCGATCTCTTGTGAGGAAGCAAAGTACATGATGACAATAGCGAA
AAATACTAATTTAGTCGCTTCAATGGGGTTTAATTATCGCTACTTATCCTATGTTAAGGCTTTAAAGCAATTAATTCAAA
ATGAAGGATTAGGGGAAATAGTAGTAATAAGATTGCATTTTAAAAAAAATAGCGCTTTTAGGAGAACTTCGTTTACTTGG
CGAGATGATTTTCAAAGTAATAGAACTAGTGGAGCCTTGGGAGATTTGGGAATTCATCTAATAGATTTACTATGGTTTTT
ATTTGAGAGTGATTTTAGAGAGGATACCGTTCGAACTAAAATCAAAACAAATGTTAAGGAAAAAGAAAGCAAACCAGTTT
TTGTTGATGACTATGCTGAGGTTTATGGCCAATTGGAAAATAAGGTTTTTGTTAATATTACAACATCTAAAAGTTCATTT
CCAGAGGATTGTGGTTTTAGTATAGAGGTAATAGGTACGAAAAAAGAATATAAGTATTCTTCTAAAGAGCCAAATAAATA
TATACTCTTTGATGGATTGGAAAAACATGAAATCGCATTACCATTACCTTTACTAGTCGATCCAGAAAACGAGATTTTTG
AATGGTCTGATTCTTTTAGAAGTGAAATTTTAGAATGGGCAAAGGCTGCGGAAGATGGTCCTAAAAAGTCTGTAGCAACA
TTTGAAGATGGATTTCGTTCACAAGTTATTTTGGATATGTTTTTTGATAAAAGCAGTAGTAATAAAGAGCGATCTGTAGC
AACTATTTAG

Upstream 100 bases:

>100_bases
AGGCTAAAAAAATACACTCAATGTTAGCTCAAGGTGAATACTCGATTGGAATTTTAAATACTCTAAAGCACATTATTAAT
TAAAAGGAGATGTTCATATA

Downstream 100 bases:

>100_bases
TTTTATGGTAAAAACAGGGGTTTAGAACTTTTACTTAAATCCCTGTTTTTATTTTGGATTGGAGTTGAGAAAAGATGCGG
TTAATGTTTTATTATGGTTG

Product: Gfo/Idh/MocA family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 349

Protein sequence:

>349_residues
MNIGIIGAGSIARAHSRALSTIDNCKLVGVYDVNSENADKLVGDFGGKVFDSYEELLEVVDGVIISSPNFCHKSQAVQAL
LTNKHVLCEKPMAISCEEAKYMMTIAKNTNLVASMGFNYRYLSYVKALKQLIQNEGLGEIVVIRLHFKKNSAFRRTSFTW
RDDFQSNRTSGALGDLGIHLIDLLWFLFESDFREDTVRTKIKTNVKEKESKPVFVDDYAEVYGQLENKVFVNITTSKSSF
PEDCGFSIEVIGTKKEYKYSSKEPNKYILFDGLEKHEIALPLPLLVDPENEIFEWSDSFRSEILEWAKAAEDGPKKSVAT
FEDGFRSQVILDMFFDKSSSNKERSVATI

Sequences:

>Translated_349_residues
MNIGIIGAGSIARAHSRALSTIDNCKLVGVYDVNSENADKLVGDFGGKVFDSYEELLEVVDGVIISSPNFCHKSQAVQAL
LTNKHVLCEKPMAISCEEAKYMMTIAKNTNLVASMGFNYRYLSYVKALKQLIQNEGLGEIVVIRLHFKKNSAFRRTSFTW
RDDFQSNRTSGALGDLGIHLIDLLWFLFESDFREDTVRTKIKTNVKEKESKPVFVDDYAEVYGQLENKVFVNITTSKSSF
PEDCGFSIEVIGTKKEYKYSSKEPNKYILFDGLEKHEIALPLPLLVDPENEIFEWSDSFRSEILEWAKAAEDGPKKSVAT
FEDGFRSQVILDMFFDKSSSNKERSVATI
>Mature_349_residues
MNIGIIGAGSIARAHSRALSTIDNCKLVGVYDVNSENADKLVGDFGGKVFDSYEELLEVVDGVIISSPNFCHKSQAVQAL
LTNKHVLCEKPMAISCEEAKYMMTIAKNTNLVASMGFNYRYLSYVKALKQLIQNEGLGEIVVIRLHFKKNSAFRRTSFTW
RDDFQSNRTSGALGDLGIHLIDLLWFLFESDFREDTVRTKIKTNVKEKESKPVFVDDYAEVYGQLENKVFVNITTSKSSF
PEDCGFSIEVIGTKKEYKYSSKEPNKYILFDGLEKHEIALPLPLLVDPENEIFEWSDSFRSEILEWAKAAEDGPKKSVAT
FEDGFRSQVILDMFFDKSSSNKERSVATI

Specific function: Part of the ntdABC operon that biosynthesizes the NTD (3,3'-neotrehalosadiamine) antibiotic [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI1787574, Length=194, Percent_Identity=30.4123711340206, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI87082405, Length=191, Percent_Identity=27.7486910994764, Blast_Score=77, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19920536, Length=294, Percent_Identity=22.7891156462585, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 39410; Mature: 39410

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIGIIGAGSIARAHSRALSTIDNCKLVGVYDVNSENADKLVGDFGGKVFDSYEELLEVV
CCEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHH
DGVIISSPNFCHKSQAVQALLTNKHVLCEKPMAISCEEAKYMMTIAKNTNLVASMGFNYR
CCEEECCCCCHHHHHHHHHHHHCCCEEECCCCEEECCCCEEEEEEECCCCEEEECCCCHH
YLSYVKALKQLIQNEGLGEIVVIRLHFKKNSAFRRTSFTWRDDFQSNRTSGALGDLGIHL
HHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEECCCCCHHHHCCCCCCCCHHHHHHHH
IDLLWFLFESDFREDTVRTKIKTNVKEKESKPVFVDDYAEVYGQLENKVFVNITTSKSSF
HHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCEEEECHHHHHHHCCCEEEEEEECCCCCC
PEDCGFSIEVIGTKKEYKYSSKEPNKYILFDGLEKHEIALPLPLLVDPENEIFEWSDSFR
CCCCCCEEEEEECCHHCCCCCCCCCEEEEECCCCCCCEEECCCEEECCCHHHHHHHHHHH
SEILEWAKAAEDGPKKSVATFEDGFRSQVILDMFFDKSSSNKERSVATI
HHHHHHHHHCCCCCCCCHHHHHHCCHHHEEEHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MNIGIIGAGSIARAHSRALSTIDNCKLVGVYDVNSENADKLVGDFGGKVFDSYEELLEVV
CCEEEEECCHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHH
DGVIISSPNFCHKSQAVQALLTNKHVLCEKPMAISCEEAKYMMTIAKNTNLVASMGFNYR
CCEEECCCCCHHHHHHHHHHHHCCCEEECCCCEEECCCCEEEEEEECCCCEEEECCCCHH
YLSYVKALKQLIQNEGLGEIVVIRLHFKKNSAFRRTSFTWRDDFQSNRTSGALGDLGIHL
HHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCEEECCCCCHHHHCCCCCCCCHHHHHHHH
IDLLWFLFESDFREDTVRTKIKTNVKEKESKPVFVDDYAEVYGQLENKVFVNITTSKSSF
HHHHHHHHHCCCHHHHHHHHHHCCCHHHCCCCEEEECHHHHHHHCCCEEEEEEECCCCCC
PEDCGFSIEVIGTKKEYKYSSKEPNKYILFDGLEKHEIALPLPLLVDPENEIFEWSDSFR
CCCCCCEEEEEECCHHCCCCCCCCCEEEEECCCCCCCEEECCCEEECCCHHHHHHHHHHH
SEILEWAKAAEDGPKKSVATFEDGFRSQVILDMFFDKSSSNKERSVATI
HHHHHHHHHCCCCCCCCHHHHHHCCHHHEEEHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]