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The map label for this gene is rpiA

Identifier: 77748714

GI number: 77748714

Start: 4016957

End: 4017604

Strand: Direct

Name: rpiA

Synonym: XAC3411

Alternate gene names: 77748714

Gene position: 4016957-4017604 (Clockwise)

Preceding gene: 21244135

Following gene: 21244137

Centisome position: 77.61

GC content: 66.2

Gene sequence:

>648_bases
ATGTCCGAAGCAAAACGCCTGGCCGCCGAGAAAGCGATCGATTACGTGGAAGACGGCATGATCGTCGGAGTGGGCACCGG
TTCGACGGTGGCTTACTTCATCGACGCGCTGGGCCGCATCGGCCATCGCATCAAGGGCGCCGTGTCCAGCTCCGAACAGA
GCACCGCGCGCCTGCGCCAGCATGGCATCGAGGTGCTGGACCTCAATCACACCGGCAATCTGTCGCTGTACGTGGACGGT
GCCGACGAGTGCGACCCGAACCGCTGCCTGATCAAGGGAGGCGGCGCAGCGCTGACGCGCGAAAAGATCATCGCCGAAGC
CAGCGAGCGCTTCATCTGCATCGTCGACCCGAGCAAGCAGGTGCCGGTGCTGGGCAAGTTCCCGCTGCCGGTGGAAGTGA
TTCCGATGGCGCGCAGCCTGGTCGCCCGGCAGATCCTGGCGCTGACCGGCGGCCAGCCGGTGTGGCGCGATGGCGTGGTG
ACCGACAACGGCAACGTGGTGCTGGACGTGCATCACCTGCAAGTCACCGACCCGGTGGGCCTGGAGCGCAGCTTGAACCA
GATTCCTGGCGTGGTCTGCGTGGGTTTGTTCGCGCGGCGCCCGGCCGACGTGGTGATCGTGGGCGGCGAGCCACCGCAGG
TGATCTGA

Upstream 100 bases:

>100_bases
GTGATCGGGATTGGGCATTGGAGATTGACCCACTGCCCGCCCGCGTTGCACCGCCTTGACGAATCTCGACTCCCCAATCA
CGAATCCCGAGCTCTTACCC

Downstream 100 bases:

>100_bases
GGATCGCGTGCGGGCCTTCGCATGCGCAGTGACGGCCCGCATTGCGAAGCGATGGCGGGTCGCACACATCGCGCTTGCAG
CAACCGCACAACGCACCGCA

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI

Number of amino acids: Translated: 215; Mature: 214

Protein sequence:

>215_residues
MSEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQHGIEVLDLNHTGNLSLYVDG
ADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQVPVLGKFPLPVEVIPMARSLVARQILALTGGQPVWRDGVV
TDNGNVVLDVHHLQVTDPVGLERSLNQIPGVVCVGLFARRPADVVIVGGEPPQVI

Sequences:

>Translated_215_residues
MSEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQHGIEVLDLNHTGNLSLYVDG
ADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQVPVLGKFPLPVEVIPMARSLVARQILALTGGQPVWRDGVV
TDNGNVVLDVHHLQVTDPVGLERSLNQIPGVVCVGLFARRPADVVIVGGEPPQVI
>Mature_214_residues
SEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQHGIEVLDLNHTGNLSLYVDGA
DECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQVPVLGKFPLPVEVIPMARSLVARQILALTGGQPVWRDGVVT
DNGNVVLDVHHLQVTDPVGLERSLNQIPGVVCVGLFARRPADVVIVGGEPPQVI

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family

Homologues:

Organism=Homo sapiens, GI94536842, Length=211, Percent_Identity=38.3886255924171, Blast_Score=116, Evalue=2e-26,
Organism=Escherichia coli, GI1789280, Length=206, Percent_Identity=62.1359223300971, Blast_Score=258, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17551758, Length=208, Percent_Identity=35.5769230769231, Blast_Score=100, Evalue=9e-22,
Organism=Saccharomyces cerevisiae, GI6324669, Length=220, Percent_Identity=32.7272727272727, Blast_Score=103, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281364072, Length=200, Percent_Identity=36, Blast_Score=104, Evalue=5e-23,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): RPIA_XANAC (Q8PH49)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643718.2
- ProteinModelPortal:   Q8PH49
- SMR:   Q8PH49
- GeneID:   1157482
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC3411
- NMPDR:   fig|190486.1.peg.3362
- HOGENOM:   HBG515603
- OMA:   DLNHTGN
- ProtClustDB:   PRK00702
- BioCyc:   XAXO190486:XAC3411-MONOMER
- BRENDA:   5.3.1.6
- HAMAP:   MF_00170
- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672
- PANTHER:   PTHR11934
- TIGRFAMs:   TIGR00021

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A

EC number: =5.3.1.6

Molecular weight: Translated: 22874; Mature: 22742

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQ
CCHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HGIEVLDLNHTGNLSLYVDGADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQ
CCCEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCC
VPVLGKFPLPVEVIPMARSLVARQILALTGGQPVWRDGVVTDNGNVVLDVHHLQVTDPVG
CCEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEEEEEECCCCC
LERSLNQIPGVVCVGLFARRPADVVIVGGEPPQVI
HHHHHHHCCHHEEHHHHHCCCCCEEEECCCCCCCC
>Mature Secondary Structure 
SEAKRLAAEKAIDYVEDGMIVGVGTGSTVAYFIDALGRIGHRIKGAVSSSEQSTARLRQ
CHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
HGIEVLDLNHTGNLSLYVDGADECDPNRCLIKGGGAALTREKIIAEASERFICIVDPSKQ
CCCEEEEECCCCCEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCC
VPVLGKFPLPVEVIPMARSLVARQILALTGGQPVWRDGVVTDNGNVVLDVHHLQVTDPVG
CCEEECCCCCEEHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCEEEEEEEEEECCCCC
LERSLNQIPGVVCVGLFARRPADVVIVGGEPPQVI
HHHHHHHCCHHEEHHHHHCCCCCEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217