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The map label for this gene is cheW [H]

Identifier: 77748621

GI number: 77748621

Start: 2229212

End: 2230486

Strand: Reverse

Name: cheW [H]

Synonym: XAC1906

Alternate gene names: 77748621

Gene position: 2230486-2229212 (Counterclockwise)

Preceding gene: 21242651

Following gene: 21242649

Centisome position: 43.1

GC content: 68.78

Gene sequence:

>1275_bases
ATGAGCAACTCCACCGCCAACGGTGAATTGGACGATTATCTGGAAGGCCTGCTGCACGATGCGGGCGTGGAGATCGTCGC
CCCGCCCGCGGCCACCGCAGCGACGGTCGATACGCCGCCAATTGCGGATGCCGATCTCGCGCTGGCCGAGCCGCCGGTCG
AGACGGCCGCACTTCCCGAAGCCGCTACTGTCTCCGAGGCTGCCACCTCCAACGCGATTGCCGCGGTGCGTAGCGCCGAT
GCGATCGCCGCCGATTTCCTGGCAGAAATGGACGCCGACCCGGCATTCGCCCCCCCGGTCAAGGCCGCGCCCAGCGCTGC
CGACATCGCCGCCGACTTTCTGGCCGAAATGGATGCCGACCCGGCATTCGCTCCGCCGGTCAAGGCCGCACCCAGCGCCG
CCGACATCGCCGCCGACTTTCTGGCCGAAATGGATGCCGACCCGGCATTCGCTCCGCCGGTCAAGGCCGCACCCAGCGCT
GCGGACATCGCCGCCGACTTTCTGGCCGAAATGGATGCCGACCCGGCGTTCGCTCCGCCGGTCAACGCCGCGCCCAGCGC
TGCCGACATCGCCGCCGACTTTCTGGCCGAAATGGATGCCGACCCGGCGTTCGGAGCCGCACCCACCGCAGTGGACCTGA
TCACCGCAGATCTGCTGGCAGAAATGGATGCCGACCCCGCCTTCGGACTGGAGGCTGCACCGGTCGCGGCGCTCGCACCA
GCCCCGGTCCCAGCGCCCGCCCTGCCCCCGCGTGCAGCACCCGCGCCGGCACGCGCTCCGGCACCGACCGGGCTGCAGGC
ACTGCTGGCGCCTGGCCAGGCCGACAAGATTCACGCCGAACGCCGCGCCAGCGAACGCAGCACCCGCTGGCTGCGTCTGC
GCTGCGGCGAACAGACCTATGCGCTGGAATTGCTCAAGGTGCAGGAAGTGGTGTTGCCGGTGCCGCTGCTGCCGCTGCGC
GGCACGCCCAGCGCCATGCTCGGCATCATGAACCTGCGCGGCCAGGTGGTCCCGGTGATCGATCTGGGCATCCACCTGGG
CTCCTCGCCGGTGGACATGGATCTGCAGACCCGCGTGGTGGTCCTGGAAGAAAACGGCGAAACCATGGGCCTGCGCGTGT
CGGCCGTGGAAGACGTCACCAGCCTCACCGATCAGCAGATCGAGCCGCCGGACAACGCGCGCCTGTGCCGCATCTACAAC
AACCTGTTCCGCGGTGTCGCACGTCTTGGCCATCAGCCGATGATCCTGCTCGATGCCACCCATCTGCTGCATTGA

Upstream 100 bases:

>100_bases
CTGCCGTTGGCGGCGACTATCAGGGCCGCGGTCTGTCCGCGTATCGCCGCGCGCTGGAATGGGTGCTGGCCGATGACGCG
ATGCGTATGGAGCAAGCCGC

Downstream 100 bases:

>100_bases
TGCGCGCCTAGCTTGCCCGCACCTGCACGCACGACGATTCACCGTTAAAGCTTTTCCGCCCCCCGCCGTTAGTACGCATA
GAACCATCCGTTCGGAGCAA

Product: chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MSNSTANGELDDYLEGLLHDAGVEIVAPPAATAATVDTPPIADADLALAEPPVETAALPEAATVSEAATSNAIAAVRSAD
AIAADFLAEMDADPAFAPPVKAAPSAADIAADFLAEMDADPAFAPPVKAAPSAADIAADFLAEMDADPAFAPPVKAAPSA
ADIAADFLAEMDADPAFAPPVNAAPSAADIAADFLAEMDADPAFGAAPTAVDLITADLLAEMDADPAFGLEAAPVAALAP
APVPAPALPPRAAPAPARAPAPTGLQALLAPGQADKIHAERRASERSTRWLRLRCGEQTYALELLKVQEVVLPVPLLPLR
GTPSAMLGIMNLRGQVVPVIDLGIHLGSSPVDMDLQTRVVVLEENGETMGLRVSAVEDVTSLTDQQIEPPDNARLCRIYN
NLFRGVARLGHQPMILLDATHLLH

Sequences:

>Translated_424_residues
MSNSTANGELDDYLEGLLHDAGVEIVAPPAATAATVDTPPIADADLALAEPPVETAALPEAATVSEAATSNAIAAVRSAD
AIAADFLAEMDADPAFAPPVKAAPSAADIAADFLAEMDADPAFAPPVKAAPSAADIAADFLAEMDADPAFAPPVKAAPSA
ADIAADFLAEMDADPAFAPPVNAAPSAADIAADFLAEMDADPAFGAAPTAVDLITADLLAEMDADPAFGLEAAPVAALAP
APVPAPALPPRAAPAPARAPAPTGLQALLAPGQADKIHAERRASERSTRWLRLRCGEQTYALELLKVQEVVLPVPLLPLR
GTPSAMLGIMNLRGQVVPVIDLGIHLGSSPVDMDLQTRVVVLEENGETMGLRVSAVEDVTSLTDQQIEPPDNARLCRIYN
NLFRGVARLGHQPMILLDATHLLH
>Mature_423_residues
SNSTANGELDDYLEGLLHDAGVEIVAPPAATAATVDTPPIADADLALAEPPVETAALPEAATVSEAATSNAIAAVRSADA
IAADFLAEMDADPAFAPPVKAAPSAADIAADFLAEMDADPAFAPPVKAAPSAADIAADFLAEMDADPAFAPPVKAAPSAA
DIAADFLAEMDADPAFAPPVNAAPSAADIAADFLAEMDADPAFGAAPTAVDLITADLLAEMDADPAFGLEAAPVAALAPA
PVPAPALPPRAAPAPARAPAPTGLQALLAPGQADKIHAERRASERSTRWLRLRCGEQTYALELLKVQEVVLPVPLLPLRG
TPSAMLGIMNLRGQVVPVIDLGIHLGSSPVDMDLQTRVVVLEENGETMGLRVSAVEDVTSLTDQQIEPPDNARLCRIYNN
LFRGVARLGHQPMILLDATHLLH

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. It physically bridges CheA to the MCPs (methyl-accepting chemotaxis proteins) to allow regulated phosphotransfer to CheY and CheB [H]

COG id: COG0835

COG function: function code NT; Chemotaxis signal transduction protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cheW-like domain [H]

Homologues:

Organism=Escherichia coli, GI1788196, Length=149, Percent_Identity=33.5570469798658, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002545 [H]

Pfam domain/function: PF01584 CheW [H]

EC number: NA

Molecular weight: Translated: 43474; Mature: 43343

Theoretical pI: Translated: 3.90; Mature: 3.90

Prosite motif: PS50851 CHEW

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNSTANGELDDYLEGLLHDAGVEIVAPPAATAATVDTPPIADADLALAEPPVETAALPE
CCCCCCCCCHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCHHHCCCC
AATVSEAATSNAIAAVRSADAIAADFLAEMDADPAFAPPVKAAPSAADIAADFLAEMDAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
PAFAPPVKAAPSAADIAADFLAEMDADPAFAPPVKAAPSAADIAADFLAEMDADPAFAPP
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
VNAAPSAADIAADFLAEMDADPAFGAAPTAVDLITADLLAEMDADPAFGLEAAPVAALAP
CCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCC
APVPAPALPPRAAPAPARAPAPTGLQALLAPGQADKIHAERRASERSTRWLRLRCGEQTY
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCEEEEEEECCHHH
ALELLKVQEVVLPVPLLPLRGTPSAMLGIMNLRGQVVPVIDLGIHLGSSPVDMDLQTRVV
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECEECCCCCCCCCCCEEEE
VLEENGETMGLRVSAVEDVTSLTDQQIEPPDNARLCRIYNNLFRGVARLGHQPMILLDAT
EEECCCCEEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECH
HLLH
HHCC
>Mature Secondary Structure 
SNSTANGELDDYLEGLLHDAGVEIVAPPAATAATVDTPPIADADLALAEPPVETAALPE
CCCCCCCCHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCCCCCCCCCCCCHHHCCCC
AATVSEAATSNAIAAVRSADAIAADFLAEMDADPAFAPPVKAAPSAADIAADFLAEMDAD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCC
PAFAPPVKAAPSAADIAADFLAEMDADPAFAPPVKAAPSAADIAADFLAEMDADPAFAPP
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
VNAAPSAADIAADFLAEMDADPAFGAAPTAVDLITADLLAEMDADPAFGLEAAPVAALAP
CCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCC
APVPAPALPPRAAPAPARAPAPTGLQALLAPGQADKIHAERRASERSTRWLRLRCGEQTY
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCEEEEEEECCHHH
ALELLKVQEVVLPVPLLPLRGTPSAMLGIMNLRGQVVPVIDLGIHLGSSPVDMDLQTRVV
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCEEEEEEECEECCCCCCCCCCCEEEE
VLEENGETMGLRVSAVEDVTSLTDQQIEPPDNARLCRIYNNLFRGVARLGHQPMILLDAT
EEECCCCEEEEEEHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECH
HLLH
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]