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The map label for this gene is ttuB [H]

Identifier: 21245073

GI number: 21245073

Start: 5156406

End: 5157776

Strand: Reverse

Name: ttuB [H]

Synonym: XAC4361

Alternate gene names: 21245073

Gene position: 5157776-5156406 (Counterclockwise)

Preceding gene: 21245074

Following gene: 21245072

Centisome position: 99.66

GC content: 67.98

Gene sequence:

>1371_bases
GTGTGGTGCCGATGCCAGGGCACTGCGTGCCGGTGGGCCTACCGACTGCTGGAGCGTGCGATGACCCAAGCCACCCGGCC
CCTGCCGCCCTCCGATGGCATGGGCCCGACCTACCGCAAGATCCTGTGGCGGCTGATCCCGTTCCTGTTCGTCTGCTACC
TGTTCAATTACCTGGACCGGGTCAACGTCGGCTTCGCCAAACTGCAGATGCTGGGCGACCTGGGCATGAGCGAGACCGTG
TACGGGCTGGGCGCGGGCATCTTCTTCATCGGTTACCTGGCCTGCGGGGTGCCGAGCAATCTGATCCTGCAGCGCATCGG
TGCCCGGCGCTGGGTGGCGATCATGATGGTCAGCTGGGGCCTGCTCTCCACCTGCCTGCTGTTCGTGCGCACCCCGGCCG
GCTTCTACACCCTGCGCCTGCTCACCGGTGCGGCCGAGGCGGGCTTCTTCCCCGGCATCGTGCTGTACCTGACGCGCTGG
TTCCCGCGTGCCCGGCATGGCCGGGTCATGACCGTCTTCATGTCGGCGATCCCGATCTCCGGGGTACTGGGCGGGCCGTT
GTCCGGCTGGATCCTGGGTCACTTCTCGGCCGGGCAGGGCGGCCTGGCCGGCTGGCAATGGATGTTCCTGCTGCAGGGCC
TGCCGACCGTGGTGCTGGGCATCGGGGTGTGGTTCCTGCTCAGCGACGGCGTGCAACAGGCCAGCTGGCTCAACCCGCAG
GAAAAACAGGCCTTGGCACGCGTGCTGGCCGAGGACGAAGCCGGCAAGCCGGCCGGTGCGTCCACTTCGCTGGGCGCGGT
GCTGCGTAACCCGGCGGTGTGGCTGCTGGGCACGGTGTATTTCTGCATCCAGAGCGGGGTGTATGCGATCAACTTCTGGT
TGCCTTCGATCATCCAGGGCAGCGGCGTCACCGACCCGATCCGCATCGGTCTGATGAGCGCCATCCCGTACCTGGCCGCG
GCGGTGTTCATGGTGTTGATGGGCCGTTCGGCCGACCGCCGCGGCGAACGTCGCTGGCACTTGGTGATTCCGTTGCTGAT
GGGCGCGGCCGGCCTGTGCATTGCCGCCAGCGTCAGCGACAACCTGGGCCTGGCCTTGTTCGGCATGACCCTGGCCACGA
TGGGGGCGGTCAGCGGCTTGCCGCTGTTCTGGCCGCTGACCAACGGCTTTCTCACTGTCGCCGCCGCCGCCGGTGGACTG
GCGCTGATCAATTCCACCGGCCAGGTCGCCGGCTTCGTCAGCCCGTATCTGGTGGGCTGGATCAAGGACACCACCCACAG
CACCGAAGTGGCGCTGTACGTGCTGGCCGGCGCCATGCTGCTGGGCGCCGCGCTGGTGCTGCGGGTGCCGGCGCGCGCGG
TGAACCAGTGA

Upstream 100 bases:

>100_bases
TTGGGCAGTTGCACAAAAACCGGCGTCTTCATGCCCGCAGACAGGTAGCAGGCTGACGATGCTTCCGGGAAAAAGCTCCA
ACTAGAATGCGCCGACCCCC

Downstream 100 bases:

>100_bases
TGTGCCCGTCCCAGCGAGTGTCCGCATGAAGATCGTCATTGCCCCCGATTCGTACAAGGAAAGCCTGTCCGCGCTGGACG
TGGCGACGCAGATCGAGGCG

Product: MFS transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MWCRCQGTACRWAYRLLERAMTQATRPLPPSDGMGPTYRKILWRLIPFLFVCYLFNYLDRVNVGFAKLQMLGDLGMSETV
YGLGAGIFFIGYLACGVPSNLILQRIGARRWVAIMMVSWGLLSTCLLFVRTPAGFYTLRLLTGAAEAGFFPGIVLYLTRW
FPRARHGRVMTVFMSAIPISGVLGGPLSGWILGHFSAGQGGLAGWQWMFLLQGLPTVVLGIGVWFLLSDGVQQASWLNPQ
EKQALARVLAEDEAGKPAGASTSLGAVLRNPAVWLLGTVYFCIQSGVYAINFWLPSIIQGSGVTDPIRIGLMSAIPYLAA
AVFMVLMGRSADRRGERRWHLVIPLLMGAAGLCIAASVSDNLGLALFGMTLATMGAVSGLPLFWPLTNGFLTVAAAAGGL
ALINSTGQVAGFVSPYLVGWIKDTTHSTEVALYVLAGAMLLGAALVLRVPARAVNQ

Sequences:

>Translated_456_residues
MWCRCQGTACRWAYRLLERAMTQATRPLPPSDGMGPTYRKILWRLIPFLFVCYLFNYLDRVNVGFAKLQMLGDLGMSETV
YGLGAGIFFIGYLACGVPSNLILQRIGARRWVAIMMVSWGLLSTCLLFVRTPAGFYTLRLLTGAAEAGFFPGIVLYLTRW
FPRARHGRVMTVFMSAIPISGVLGGPLSGWILGHFSAGQGGLAGWQWMFLLQGLPTVVLGIGVWFLLSDGVQQASWLNPQ
EKQALARVLAEDEAGKPAGASTSLGAVLRNPAVWLLGTVYFCIQSGVYAINFWLPSIIQGSGVTDPIRIGLMSAIPYLAA
AVFMVLMGRSADRRGERRWHLVIPLLMGAAGLCIAASVSDNLGLALFGMTLATMGAVSGLPLFWPLTNGFLTVAAAAGGL
ALINSTGQVAGFVSPYLVGWIKDTTHSTEVALYVLAGAMLLGAALVLRVPARAVNQ
>Mature_456_residues
MWCRCQGTACRWAYRLLERAMTQATRPLPPSDGMGPTYRKILWRLIPFLFVCYLFNYLDRVNVGFAKLQMLGDLGMSETV
YGLGAGIFFIGYLACGVPSNLILQRIGARRWVAIMMVSWGLLSTCLLFVRTPAGFYTLRLLTGAAEAGFFPGIVLYLTRW
FPRARHGRVMTVFMSAIPISGVLGGPLSGWILGHFSAGQGGLAGWQWMFLLQGLPTVVLGIGVWFLLSDGVQQASWLNPQ
EKQALARVLAEDEAGKPAGASTSLGAVLRNPAVWLLGTVYFCIQSGVYAINFWLPSIIQGSGVTDPIRIGLMSAIPYLAA
AVFMVLMGRSADRRGERRWHLVIPLLMGAAGLCIAASVSDNLGLALFGMTLATMGAVSGLPLFWPLTNGFLTVAAAAGGL
ALINSTGQVAGFVSPYLVGWIKDTTHSTEVALYVLAGAMLLGAALVLRVPARAVNQ

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=386, Percent_Identity=22.7979274611399, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI87082071, Length=421, Percent_Identity=36.8171021377672, Blast_Score=239, Evalue=3e-64,
Organism=Escherichia coli, GI2367379, Length=461, Percent_Identity=25.3796095444685, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1789152, Length=418, Percent_Identity=24.6411483253589, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789515, Length=425, Percent_Identity=24.4705882352941, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI87082320, Length=447, Percent_Identity=23.489932885906, Blast_Score=76, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17552542, Length=396, Percent_Identity=24.4949494949495, Blast_Score=65, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=233, Percent_Identity=26.1802575107296, Blast_Score=95, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6321698, Length=359, Percent_Identity=23.6768802228412, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6319876, Length=256, Percent_Identity=26.5625, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324410, Length=149, Percent_Identity=26.8456375838926, Blast_Score=69, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323032, Length=239, Percent_Identity=23.4309623430962, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=252, Percent_Identity=22.2222222222222, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24584153, Length=377, Percent_Identity=25.1989389920424, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24583789, Length=371, Percent_Identity=24.5283018867925, Blast_Score=69, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49074; Mature: 49074

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCC
>Mature Secondary Structure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HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]