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The map label for this gene is yegE [H]

Identifier: 21245070

GI number: 21245070

Start: 5151929

End: 5153656

Strand: Reverse

Name: yegE [H]

Synonym: XAC4358

Alternate gene names: 21245070

Gene position: 5153656-5151929 (Counterclockwise)

Preceding gene: 21245071

Following gene: 21245069

Centisome position: 99.58

GC content: 68.58

Gene sequence:

>1728_bases
GTGTCATCTGCGTCCAGCGAGGCCCAGCGCCTGGCACGTCTGGCGTTGTTGCAGGTGGTCGACACCGCCGCCGAGCCGTT
CTTCGATGCGCTGGCCGCTGCCGCGCAGGCGATCGCCGGTACCCCCATCGCACTGGTCTCGCTGGTGGACGAACGTCGGC
AGTGGTGGAAGGCCAACATCGGCCTGCCGGGGGTTTCGGAAACCCCACGCGAGCTGGCGTTCTGCACCTACACCATCCAG
GGCGATGCGGTGATGGAAGTGCGCGACGCGCCGGCCGACCCACGCTTCCACGACAACGCCCTGGTCACCGATGCGCCCGG
TATCCGCTATTACGCCGGTGCGCCCATCGTGCTGCCGGATGGCTTACGCATGGGCACCGTGTGCGTGATCGACCAGCGCC
CGCGCGCGCTGGAGCCGGCGCAGTTGCAGGCCTTGCAGCAACTGGCCAAGGTGGCTGCCGAAGGCCTGGAGCAACGCCGC
GTGATGCTCGAGCGTGAGGCGGCCAACGCCCAGCTGCAGCAGCGGCTGCGCGAGAGCGAGGCGTTTCTGGAGCGCACCGG
TCGGGTGGCCGGGGTCGGCGGGTGGGAGGTGGATGTGGCCAGCGGCACGCTGATCTGGTCGGACCAGACCTGCCGGCTGC
ACGATGTTCCGCCCGGTTACCGGCCCAGCCTGACCGAGGCGATCGGCTTCTACCCGCTGGAGGCGCGAGCGGTCATCACC
GAAGCGGTCGACGCCTGCGTGCGGGACGGCACGTCCTGGGATCTGGAGCTGCCGCTGACCAGCGCCACCGGGCGGCGGCT
ATGGGTACACAGCACCGGCTCGGTGGAACATGTGGATGGGCGCAAACGCCTGATCGGCGCGGTCCAGGACGTGACCGACC
GGCATCGGGCGGTGGATGCGCTGGCCGCCAGCGAGCGCAAGTTCCGCAAGATGTTCCAGTACAGCCTGGGCCTGATCTGC
ACCCACGACATGCATGGCCGGCTGGTCAGCATCAACCCGGCCGCCGCACGCTCGCTCGGCCGCAGCGTCGAGCAGATGGA
AGGCCGCTCGCTGGTGGAATTCGTGCGCCCCGAGCGCCACGCCGCCTTGCGGGGGTACCTCTCGCGGATGGTGCTCGATG
GCCAGGATTCGGGCGTGATCGAACTGGTGGCCGGCGACGGCAGTCTGCGCCATTGGCAGTACCACAACGTGCTGGACGTG
GAATCCGACGCCACGGTGGTGCTGGCACATGCCCAGGACATCACCAACCAGTACCGGCAGGAAAAGCAGCTGTTGGAATG
GTCGTTCACCGACCCGCTGACCAACTGCTACAACCGCCGCTTCCTGGACGAGCTGGACAAGCGCGACCCCGCCGTGCGCT
GGGGTTGCATCGTGGTGGATCTGGACAAGTTCAAACTGGTCAACGACACCCATGGCCACCAGCGTGGCGACGAGGTGTTG
GTGCAGATGGCGTGGTTCCTCAACCAGCCGCTGCGCACCCAGGACCGCCTGGTACGCCTGGGCGGCGACGAATTCCTGGT
GTTGCTGCACCAGGCCAGCCAGACACAGCTGGACGCGTTGAAGCGCGACTACATGGGGGCCAGCGAGGACGCGCCGATCC
GCTTCACCCTCGGCACCGCCCTGCGCCAGGACGGCGAAGCGCTGGCGGCGGTGGTCGATCGCGCCGACCACTCGCTGTAC
TCGCTGCGCCGCGCCCGCCGCGGCACGGGTACCAGCGACCAGCGCTGA

Upstream 100 bases:

>100_bases
CGGTGGCGCACGCAACGCCGCCTTGGCGGGTATGCGCAGTCCGCTAGACTGCGCGGATTGCCCGGCTGCGAGCGCTCCGT
TGAACCAGTGCGATACCGTC

Downstream 100 bases:

>100_bases
CCGTCTGCGCAGGCTTTGCGCAGACGGAAGCTGCACCGAACCCATGTGAGAGGCCGCGGACGTGCCGATGAATACGCGTT
CGCCTATCATGTAAACGTTT

Product: hypothetical protein

Products: NA

Alternate protein names: DGC [H]

Number of amino acids: Translated: 575; Mature: 574

Protein sequence:

>575_residues
MSSASSEAQRLARLALLQVVDTAAEPFFDALAAAAQAIAGTPIALVSLVDERRQWWKANIGLPGVSETPRELAFCTYTIQ
GDAVMEVRDAPADPRFHDNALVTDAPGIRYYAGAPIVLPDGLRMGTVCVIDQRPRALEPAQLQALQQLAKVAAEGLEQRR
VMLEREAANAQLQQRLRESEAFLERTGRVAGVGGWEVDVASGTLIWSDQTCRLHDVPPGYRPSLTEAIGFYPLEARAVIT
EAVDACVRDGTSWDLELPLTSATGRRLWVHSTGSVEHVDGRKRLIGAVQDVTDRHRAVDALAASERKFRKMFQYSLGLIC
THDMHGRLVSINPAAARSLGRSVEQMEGRSLVEFVRPERHAALRGYLSRMVLDGQDSGVIELVAGDGSLRHWQYHNVLDV
ESDATVVLAHAQDITNQYRQEKQLLEWSFTDPLTNCYNRRFLDELDKRDPAVRWGCIVVDLDKFKLVNDTHGHQRGDEVL
VQMAWFLNQPLRTQDRLVRLGGDEFLVLLHQASQTQLDALKRDYMGASEDAPIRFTLGTALRQDGEALAAVVDRADHSLY
SLRRARRGTGTSDQR

Sequences:

>Translated_575_residues
MSSASSEAQRLARLALLQVVDTAAEPFFDALAAAAQAIAGTPIALVSLVDERRQWWKANIGLPGVSETPRELAFCTYTIQ
GDAVMEVRDAPADPRFHDNALVTDAPGIRYYAGAPIVLPDGLRMGTVCVIDQRPRALEPAQLQALQQLAKVAAEGLEQRR
VMLEREAANAQLQQRLRESEAFLERTGRVAGVGGWEVDVASGTLIWSDQTCRLHDVPPGYRPSLTEAIGFYPLEARAVIT
EAVDACVRDGTSWDLELPLTSATGRRLWVHSTGSVEHVDGRKRLIGAVQDVTDRHRAVDALAASERKFRKMFQYSLGLIC
THDMHGRLVSINPAAARSLGRSVEQMEGRSLVEFVRPERHAALRGYLSRMVLDGQDSGVIELVAGDGSLRHWQYHNVLDV
ESDATVVLAHAQDITNQYRQEKQLLEWSFTDPLTNCYNRRFLDELDKRDPAVRWGCIVVDLDKFKLVNDTHGHQRGDEVL
VQMAWFLNQPLRTQDRLVRLGGDEFLVLLHQASQTQLDALKRDYMGASEDAPIRFTLGTALRQDGEALAAVVDRADHSLY
SLRRARRGTGTSDQR
>Mature_574_residues
SSASSEAQRLARLALLQVVDTAAEPFFDALAAAAQAIAGTPIALVSLVDERRQWWKANIGLPGVSETPRELAFCTYTIQG
DAVMEVRDAPADPRFHDNALVTDAPGIRYYAGAPIVLPDGLRMGTVCVIDQRPRALEPAQLQALQQLAKVAAEGLEQRRV
MLEREAANAQLQQRLRESEAFLERTGRVAGVGGWEVDVASGTLIWSDQTCRLHDVPPGYRPSLTEAIGFYPLEARAVITE
AVDACVRDGTSWDLELPLTSATGRRLWVHSTGSVEHVDGRKRLIGAVQDVTDRHRAVDALAASERKFRKMFQYSLGLICT
HDMHGRLVSINPAAARSLGRSVEQMEGRSLVEFVRPERHAALRGYLSRMVLDGQDSGVIELVAGDGSLRHWQYHNVLDVE
SDATVVLAHAQDITNQYRQEKQLLEWSFTDPLTNCYNRRFLDELDKRDPAVRWGCIVVDLDKFKLVNDTHGHQRGDEVLV
QMAWFLNQPLRTQDRLVRLGGDEFLVLLHQASQTQLDALKRDYMGASEDAPIRFTLGTALRQDGEALAAVVDRADHSLYS
LRRARRGTGTSDQR

Specific function: Cyclic-di-GMP is a second messenger which controls cell surface-associated traits in bacteria [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PAS (PER-ARNT-SIM) domains [H]

Homologues:

Organism=Escherichia coli, GI1788381, Length=429, Percent_Identity=25.8741258741259, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081881, Length=192, Percent_Identity=31.7708333333333, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI145693134, Length=154, Percent_Identity=31.8181818181818, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787262, Length=126, Percent_Identity=34.1269841269841, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787541, Length=182, Percent_Identity=29.6703296703297, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI87081974, Length=99, Percent_Identity=37.3737373737374, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082007, Length=111, Percent_Identity=38.7387387387387, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR007895
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013656
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF05231 MASE1; PF08447 PAS_3; PF08448 PAS_4 [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 63908; Mature: 63777

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSASSEAQRLARLALLQVVDTAAEPFFDALAAAAQAIAGTPIALVSLVDERRQWWKANI
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
GLPGVSETPRELAFCTYTIQGDAVMEVRDAPADPRFHDNALVTDAPGIRYYAGAPIVLPD
CCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEECCCCCEEECCCCEECCC
GLRMGTVCVIDQRPRALEPAQLQALQQLAKVAAEGLEQRRVMLEREAANAQLQQRLRESE
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFLERTGRVAGVGGWEVDVASGTLIWSDQTCRLHDVPPGYRPSLTEAIGFYPLEARAVIT
HHHHHCCCEEECCCEEEEECCCEEEECCCCEEEECCCCCCCCCHHHHHCCCCCHHHHHHH
EAVDACVRDGTSWDLELPLTSATGRRLWVHSTGSVEHVDGRKRLIGAVQDVTDRHRAVDA
HHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHH
LAASERKFRKMFQYSLGLICTHDMHGRLVSINPAAARSLGRSVEQMEGRSLVEFVRPERH
HHHHHHHHHHHHHHHCCEEEEECCCCEEEEECHHHHHHHHHHHHHHCCHHHHHHHCCHHH
AALRGYLSRMVLDGQDSGVIELVAGDGSLRHWQYHNVLDVESDATVVLAHAQDITNQYRQ
HHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCEEECCCCCEEEEEEHHHHHHHHHH
EKQLLEWSFTDPLTNCYNRRFLDELDKRDPAVRWGCIVVDLDKFKLVNDTHGHQRGDEVL
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCEEEECCCCCCCHHHHHH
VQMAWFLNQPLRTQDRLVRLGGDEFLVLLHQASQTQLDALKRDYMGASEDAPIRFTLGTA
HHHHHHHCCCCCCHHHHEEECCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECHH
LRQDGEALAAVVDRADHSLYSLRRARRGTGTSDQR
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SSASSEAQRLARLALLQVVDTAAEPFFDALAAAAQAIAGTPIALVSLVDERRQWWKANI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCC
GLPGVSETPRELAFCTYTIQGDAVMEVRDAPADPRFHDNALVTDAPGIRYYAGAPIVLPD
CCCCCCCCCCCEEEEEEEECCCEEEEEECCCCCCCCCCCEEEECCCCCEEECCCCEECCC
GLRMGTVCVIDQRPRALEPAQLQALQQLAKVAAEGLEQRRVMLEREAANAQLQQRLRESE
CCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFLERTGRVAGVGGWEVDVASGTLIWSDQTCRLHDVPPGYRPSLTEAIGFYPLEARAVIT
HHHHHCCCEEECCCEEEEECCCEEEECCCCEEEECCCCCCCCCHHHHHCCCCCHHHHHHH
EAVDACVRDGTSWDLELPLTSATGRRLWVHSTGSVEHVDGRKRLIGAVQDVTDRHRAVDA
HHHHHHHHCCCCCEEEEEEECCCCCEEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHHH
LAASERKFRKMFQYSLGLICTHDMHGRLVSINPAAARSLGRSVEQMEGRSLVEFVRPERH
HHHHHHHHHHHHHHHCCEEEEECCCCEEEEECHHHHHHHHHHHHHHCCHHHHHHHCCHHH
AALRGYLSRMVLDGQDSGVIELVAGDGSLRHWQYHNVLDVESDATVVLAHAQDITNQYRQ
HHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCEEECCCCCEEEEEEHHHHHHHHHH
EKQLLEWSFTDPLTNCYNRRFLDELDKRDPAVRWGCIVVDLDKFKLVNDTHGHQRGDEVL
HHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEEEEECCEEEECCCCCCCHHHHHH
VQMAWFLNQPLRTQDRLVRLGGDEFLVLLHQASQTQLDALKRDYMGASEDAPIRFTLGTA
HHHHHHHCCCCCCHHHHEEECCCEEEEEEECCCHHHHHHHHHHHCCCCCCCCEEEEECHH
LRQDGEALAAVVDRADHSLYSLRRARRGTGTSDQR
HHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 6094528; 7984428 [H]