Click here to switch to the map view.

The map label for this gene is uahA [H]

Identifier: 21245038

GI number: 21245038

Start: 5111104

End: 5114751

Strand: Reverse

Name: uahA [H]

Synonym: XAC4326

Alternate gene names: 21245038

Gene position: 5114751-5111104 (Counterclockwise)

Preceding gene: 21245039

Following gene: 21245037

Centisome position: 98.83

GC content: 65.32

Gene sequence:

>3648_bases
ATGTTCAAGAAAATCCTCATCGCCAATCGTGGGGAGATCGCGGTGCGCATCGCGCGCACGCTCAAGAAGATGGGAGTGAC
GTCGGTCGCGGTGTATTCCGACGCTGACCATGACAGCCTGCACGTGAGCGTCGCCGACGAAGCTGTGGCGTTGAACAGCG
GCGGCAGCAGCAGCGCCGCCGAAACCTATTTGCGTGGCGATCGCATCCTGGAGATTGCCCGGAAGACCGGTGCCGGGGCC
GTCATCCCCGGTTATGGCTTTCTGTCCGAAAACACCACGTTCGCCGAGCAATGTGCGGAGGCCGGCGTCGTCTTCGTCGG
TCCCACACCCGAGCAAGTGCGCCGCTTTGGCCTCAAGCACACCGCGCGCGCGATCGCCGAGGCCGCTGGCGTGCCGCTGA
CACCTGGCACCGGCCTGCTGCAAAGTCTGGACGATGCGAAAGTCGCTGCACAGCACATCGGGTATCCCGTCATGCTCAAG
AGCACGGCCGGCGGCGGTGGCATCGGTCTCTCGCGCTGCGATAACGCAGCCGAACTGGCCACGGCCTACGATTCGGTACA
GCGCCTTGGCCAGAACTTCTTCAAGGACAGCGGCGTCTTCATCGAAGGCTTCGTTGCCAATGCGCGCCATGTCGAAGTGC
AGATCTTCGGCGACGGCAAGGGACGCGTTGTGGCGCTGGGCGAGCGCGACTGCTCGCTGCAGCGGCGGCACCAGAAGGTG
GTCGAGGAAACACCTGCGCCGCACCTGCCGGACGCGACCCGCGCCGCCTTGCTGGACGCCGCCGTGAAGCTGGGCGAAGC
GGTGAACTATGTCTCGGCCGGCACGGTGGAATTCATCTATGACGCTGCGCGCGATGCCTTCTACTTTCTTGAGGTCAACA
CGCGCCTGCAGGTCGAGCATCCCATCACCGAGGCGGTCACCGGGCTGGATCTGGTGGAATGGATGGTACGCATTGCCGCT
GGCGAGCCGCCATCCTTCGATGATCTGCCCACGCCGCGGGGCACTGCCATCGAAGTGCGCGTCTATGCCGAGAACCCCGT
GCGCGGCTTTCAGCCTGCGCCCGGCATACTGACCGATGTTCAGTTCCCCGAAGACGTGCGCGTGGACACATGGGTGCAGA
CCGGCACCGAGGTGTCTGCCAACTACGACCCACTGATCGCCAAGGTCATCGCCTACGGGGCGCACCGCGAGGAAGCCCGC
CAGAAGTTGCTGATGGCGCTGGAGCTGACGCGCCTGCACGGCAGCGCCACCAACCTGGACTACCTGCGCAGCATCCTGCA
AAGCAGGGAATTTTCGGCCGGGACGGTGTCCACTTTGCTGCTGGACCGCTACGACTATGTCTCGCCCGTGGTCGAGGTGC
TGGAATCGGGCACCTACACCACCGTGCAGGATTACCCTGGACGTACCGGATATTGGGACATCGGCGTGCCGCCCTCCGGA
CCGATGGACGACTACGCCTTTCGCCTGGCCAACCGCATCGTCGGCAACCACGAGAGCGCTGCCGGCCTGGAATGCACGCT
GCAAGGGCCGACACTCAAGTTCCATGGCGATGCGGTGATCGCGCTCACCGGCGCGCCGGCACTGGCGACACTGGACGACG
GTGAACCGCTGCCCTGGTGGAAGCCCATCGCGGTGCGCGCCAGCCAGGTGCTGCGCATCGCCAAGGCCAGCAGCGGTTGC
CGCAGCTACATCGCGATCCGGCGTGGCATCGATGTGCCTGAGTACCTGGGCAGCAAATCCACCTTCGTGCTCGGCCAGTT
CGGCGGCCATGCCGGGCGCACGCTGCGCGTGGGCGACGTGCTGCCCATCAGCCGGCCCGAGCTGGCGGTCTGCACCACGC
CAGCGCCGGCCTGCGTGCCGGCCACGCCACCGCACGAACTGGTGCCCAGCTATGGCAAACACTGGGACATCGGCGTGCTG
TACGGCCCGCACGGCGCGCCGGACTTCTTCAGCGAAGACAGCATCGCCCGCTTTTTCACGACCGACTACCAGGTGCACTA
CAACTCCAACCGCCTGGGCGTGCGGCTGGTGGGTCCCAAGCCCAAGTGGACGCGCAGCGACGGCGGCGAGGCCGGGCTGC
ACCCATCGAATGTGCACGACTGCGTGTATGCCATCGGCAGCATCAACTTCACCGGCGATACGCCGGTGATCCTGACCTGC
GATGGCCCCAGCCTGGGCGGCTTCGTGTGCCCGGCGACCATCGCCAAGGCCGAGCTCTGGAAGGTGGGTCAGGTCAAGCC
GGGCGACACCATCCGCTTCAGGCGCATGGGCTTCGATGAAGCCCTGGCGCTGGAGCAGGCGCAGGACAAGGCCATCCGCC
TGCTGCGCCCGCTGCCGGACCTGTCAGCGCGGGATCTTCCCGCTGCACCGGCGACGGTCTCGGAATGCGTGCTGGCCGAG
CTGCCTGCCGAAGGCCAACGCCCGGCCGTGGCCTACCGGCAGGCTGGAGACAAGTACATCCTGCTCGAATACGGCCCCAA
CGTGCTGGACCTGCGGCTGCGCCTGCGCGTCCATCTGCTCATGGAAGCGCTCAAGGCCGCGAAGCTGGACGGCGTGCATG
AGCTTTCGCCCGGCGTGCGCTCTGTGCAAATTCACTACGACAGCCGCGTCATCGCGCAGTCGGTGCTGGTCGAACGCCTG
ATCGCCTTGGAAACGCAATTGCCCGGCGTGGAGGGTCTTCAGGTCCCGAGCCGCATCGTGCATCTCCCCATGGCCTTCGA
GGATTCGGCCACGCTGGGTGCAGTCACACGCTACATCGAGACGGTGAAGGCCGACGCCCCCTGGCTGCCCAACAACGTGG
ACTTCATCCAGCGCATTAACGGCCTGAGCCGCCGCGAGGATGTTCGCACGACGGTTTTCGAAGCCAGTTACATGGTGATG
GGCCTGGGCGACGTGTACCTGGGCGCGCCCTGTGCCGTGCCGCTGGACCCGCGCCATCGGCTGCTCACGTCCAAGTACAA
CCCGGCACGCACCTTCACGGCTGAAGGCACGGTGGGCATTGGCGGCGTGTACATGTGCATCTATGGCATGGACTCGCCCG
GCGGCTACCAGCTCGTGGGCCGTACGGTGCCGATCTGGAATAAGTTCCTGAGAAACCGCCAGTTCGGCGCGGAGCCCTGG
CTGCTGCGCTTCTTCGACCGGGTGCGCTTCTATCCGGTGACCGAGGTTGAACTGGATCAGTTCCGGGCCGATTTCCGTGC
CGGCCGCACGCACATCAAAGTCGAAGATGCCGTGTTTGATCTGGCCGAGCACGAGCGGCTGTTAGCTCAAGACGCAAGCA
GTATCGAAGCATTCCGGGAGCGGCAGCAGACCGCCTATGCCACTGAAGTGGCGCTGTGGCAGAACGACCCCAAGGTCGAG
GCGGTGGAGGATGCCGAGGAGGCAGTCATGCAGGCTGTCGACGGAAGCGCGGTGGTGGCCGACATGTGGGGCAATGTGTG
GAAGGTTCTTGTCGACGTCGGGCAGGAAGTCCAGATCGGCGAACCGCTGGTGATCCTGGAAGCCATGAAGATGGAGTTCC
AGGTAGCCGCAAGTCAGGCAGGAACGATCGCGGCCTTGCATTGCAAGGCGGGCAAGCCTGTCGCCGCGGGAGACGCGTTG
GTGGTGATTCGACCGCACCCTGTGGCTGCGACTGTGCCTTACGCGTGA

Upstream 100 bases:

>100_bases
TGGCCCGGAAGAACTAGGCCATCGCGCCCGAACTTCACCTACCCATTCGCAGTGGGCTCCGGTCGGAGGCCAAGCCGCTG
CATCGCCCGGAGCACGCCAT

Downstream 100 bases:

>100_bases
TGGGGGTGCGCCGCGGTCGGTATGCCTGTGACGTCGCCACCAGCGGGAAGCGCCAGTGCTCCCTGGTGGAGAGCTTCTTC
GGCCAGCCCGAACGCGAGAG

Product: urea amidolyase

Products: NA

Alternate protein names: Acetyl-CoA carboxylase subunit A; ACC [H]

Number of amino acids: Translated: 1215; Mature: 1215

Protein sequence:

>1215_residues
MFKKILIANRGEIAVRIARTLKKMGVTSVAVYSDADHDSLHVSVADEAVALNSGGSSSAAETYLRGDRILEIARKTGAGA
VIPGYGFLSENTTFAEQCAEAGVVFVGPTPEQVRRFGLKHTARAIAEAAGVPLTPGTGLLQSLDDAKVAAQHIGYPVMLK
STAGGGGIGLSRCDNAAELATAYDSVQRLGQNFFKDSGVFIEGFVANARHVEVQIFGDGKGRVVALGERDCSLQRRHQKV
VEETPAPHLPDATRAALLDAAVKLGEAVNYVSAGTVEFIYDAARDAFYFLEVNTRLQVEHPITEAVTGLDLVEWMVRIAA
GEPPSFDDLPTPRGTAIEVRVYAENPVRGFQPAPGILTDVQFPEDVRVDTWVQTGTEVSANYDPLIAKVIAYGAHREEAR
QKLLMALELTRLHGSATNLDYLRSILQSREFSAGTVSTLLLDRYDYVSPVVEVLESGTYTTVQDYPGRTGYWDIGVPPSG
PMDDYAFRLANRIVGNHESAAGLECTLQGPTLKFHGDAVIALTGAPALATLDDGEPLPWWKPIAVRASQVLRIAKASSGC
RSYIAIRRGIDVPEYLGSKSTFVLGQFGGHAGRTLRVGDVLPISRPELAVCTTPAPACVPATPPHELVPSYGKHWDIGVL
YGPHGAPDFFSEDSIARFFTTDYQVHYNSNRLGVRLVGPKPKWTRSDGGEAGLHPSNVHDCVYAIGSINFTGDTPVILTC
DGPSLGGFVCPATIAKAELWKVGQVKPGDTIRFRRMGFDEALALEQAQDKAIRLLRPLPDLSARDLPAAPATVSECVLAE
LPAEGQRPAVAYRQAGDKYILLEYGPNVLDLRLRLRVHLLMEALKAAKLDGVHELSPGVRSVQIHYDSRVIAQSVLVERL
IALETQLPGVEGLQVPSRIVHLPMAFEDSATLGAVTRYIETVKADAPWLPNNVDFIQRINGLSRREDVRTTVFEASYMVM
GLGDVYLGAPCAVPLDPRHRLLTSKYNPARTFTAEGTVGIGGVYMCIYGMDSPGGYQLVGRTVPIWNKFLRNRQFGAEPW
LLRFFDRVRFYPVTEVELDQFRADFRAGRTHIKVEDAVFDLAEHERLLAQDASSIEAFRERQQTAYATEVALWQNDPKVE
AVEDAEEAVMQAVDGSAVVADMWGNVWKVLVDVGQEVQIGEPLVILEAMKMEFQVAASQAGTIAALHCKAGKPVAAGDAL
VVIRPHPVAATVPYA

Sequences:

>Translated_1215_residues
MFKKILIANRGEIAVRIARTLKKMGVTSVAVYSDADHDSLHVSVADEAVALNSGGSSSAAETYLRGDRILEIARKTGAGA
VIPGYGFLSENTTFAEQCAEAGVVFVGPTPEQVRRFGLKHTARAIAEAAGVPLTPGTGLLQSLDDAKVAAQHIGYPVMLK
STAGGGGIGLSRCDNAAELATAYDSVQRLGQNFFKDSGVFIEGFVANARHVEVQIFGDGKGRVVALGERDCSLQRRHQKV
VEETPAPHLPDATRAALLDAAVKLGEAVNYVSAGTVEFIYDAARDAFYFLEVNTRLQVEHPITEAVTGLDLVEWMVRIAA
GEPPSFDDLPTPRGTAIEVRVYAENPVRGFQPAPGILTDVQFPEDVRVDTWVQTGTEVSANYDPLIAKVIAYGAHREEAR
QKLLMALELTRLHGSATNLDYLRSILQSREFSAGTVSTLLLDRYDYVSPVVEVLESGTYTTVQDYPGRTGYWDIGVPPSG
PMDDYAFRLANRIVGNHESAAGLECTLQGPTLKFHGDAVIALTGAPALATLDDGEPLPWWKPIAVRASQVLRIAKASSGC
RSYIAIRRGIDVPEYLGSKSTFVLGQFGGHAGRTLRVGDVLPISRPELAVCTTPAPACVPATPPHELVPSYGKHWDIGVL
YGPHGAPDFFSEDSIARFFTTDYQVHYNSNRLGVRLVGPKPKWTRSDGGEAGLHPSNVHDCVYAIGSINFTGDTPVILTC
DGPSLGGFVCPATIAKAELWKVGQVKPGDTIRFRRMGFDEALALEQAQDKAIRLLRPLPDLSARDLPAAPATVSECVLAE
LPAEGQRPAVAYRQAGDKYILLEYGPNVLDLRLRLRVHLLMEALKAAKLDGVHELSPGVRSVQIHYDSRVIAQSVLVERL
IALETQLPGVEGLQVPSRIVHLPMAFEDSATLGAVTRYIETVKADAPWLPNNVDFIQRINGLSRREDVRTTVFEASYMVM
GLGDVYLGAPCAVPLDPRHRLLTSKYNPARTFTAEGTVGIGGVYMCIYGMDSPGGYQLVGRTVPIWNKFLRNRQFGAEPW
LLRFFDRVRFYPVTEVELDQFRADFRAGRTHIKVEDAVFDLAEHERLLAQDASSIEAFRERQQTAYATEVALWQNDPKVE
AVEDAEEAVMQAVDGSAVVADMWGNVWKVLVDVGQEVQIGEPLVILEAMKMEFQVAASQAGTIAALHCKAGKPVAAGDAL
VVIRPHPVAATVPYA
>Mature_1215_residues
MFKKILIANRGEIAVRIARTLKKMGVTSVAVYSDADHDSLHVSVADEAVALNSGGSSSAAETYLRGDRILEIARKTGAGA
VIPGYGFLSENTTFAEQCAEAGVVFVGPTPEQVRRFGLKHTARAIAEAAGVPLTPGTGLLQSLDDAKVAAQHIGYPVMLK
STAGGGGIGLSRCDNAAELATAYDSVQRLGQNFFKDSGVFIEGFVANARHVEVQIFGDGKGRVVALGERDCSLQRRHQKV
VEETPAPHLPDATRAALLDAAVKLGEAVNYVSAGTVEFIYDAARDAFYFLEVNTRLQVEHPITEAVTGLDLVEWMVRIAA
GEPPSFDDLPTPRGTAIEVRVYAENPVRGFQPAPGILTDVQFPEDVRVDTWVQTGTEVSANYDPLIAKVIAYGAHREEAR
QKLLMALELTRLHGSATNLDYLRSILQSREFSAGTVSTLLLDRYDYVSPVVEVLESGTYTTVQDYPGRTGYWDIGVPPSG
PMDDYAFRLANRIVGNHESAAGLECTLQGPTLKFHGDAVIALTGAPALATLDDGEPLPWWKPIAVRASQVLRIAKASSGC
RSYIAIRRGIDVPEYLGSKSTFVLGQFGGHAGRTLRVGDVLPISRPELAVCTTPAPACVPATPPHELVPSYGKHWDIGVL
YGPHGAPDFFSEDSIARFFTTDYQVHYNSNRLGVRLVGPKPKWTRSDGGEAGLHPSNVHDCVYAIGSINFTGDTPVILTC
DGPSLGGFVCPATIAKAELWKVGQVKPGDTIRFRRMGFDEALALEQAQDKAIRLLRPLPDLSARDLPAAPATVSECVLAE
LPAEGQRPAVAYRQAGDKYILLEYGPNVLDLRLRLRVHLLMEALKAAKLDGVHELSPGVRSVQIHYDSRVIAQSVLVERL
IALETQLPGVEGLQVPSRIVHLPMAFEDSATLGAVTRYIETVKADAPWLPNNVDFIQRINGLSRREDVRTTVFEASYMVM
GLGDVYLGAPCAVPLDPRHRLLTSKYNPARTFTAEGTVGIGGVYMCIYGMDSPGGYQLVGRTVPIWNKFLRNRQFGAEPW
LLRFFDRVRFYPVTEVELDQFRADFRAGRTHIKVEDAVFDLAEHERLLAQDASSIEAFRERQQTAYATEVALWQNDPKVE
AVEDAEEAVMQAVDGSAVVADMWGNVWKVLVDVGQEVQIGEPLVILEAMKMEFQVAASQAGTIAALHCKAGKPVAAGDAL
VVIRPHPVAATVPYA

Specific function: This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA [H]

COG id: COG0439

COG function: function code I; Biotin carboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 biotin carboxylation domain [H]

Homologues:

Organism=Homo sapiens, GI116805327, Length=447, Percent_Identity=47.2035794183445, Blast_Score=402, Evalue=1e-112,
Organism=Homo sapiens, GI65506442, Length=446, Percent_Identity=44.8430493273543, Blast_Score=351, Evalue=2e-96,
Organism=Homo sapiens, GI189095269, Length=446, Percent_Identity=44.8430493273543, Blast_Score=351, Evalue=2e-96,
Organism=Homo sapiens, GI295821183, Length=446, Percent_Identity=44.8430493273543, Blast_Score=351, Evalue=2e-96,
Organism=Homo sapiens, GI106049528, Length=451, Percent_Identity=41.9068736141907, Blast_Score=317, Evalue=5e-86,
Organism=Homo sapiens, GI106049295, Length=451, Percent_Identity=41.9068736141907, Blast_Score=317, Evalue=5e-86,
Organism=Homo sapiens, GI106049292, Length=451, Percent_Identity=41.9068736141907, Blast_Score=317, Evalue=5e-86,
Organism=Homo sapiens, GI38679971, Length=509, Percent_Identity=31.041257367387, Blast_Score=234, Evalue=3e-61,
Organism=Homo sapiens, GI38679960, Length=509, Percent_Identity=31.041257367387, Blast_Score=234, Evalue=3e-61,
Organism=Homo sapiens, GI38679974, Length=509, Percent_Identity=31.041257367387, Blast_Score=234, Evalue=3e-61,
Organism=Homo sapiens, GI38679977, Length=509, Percent_Identity=31.041257367387, Blast_Score=234, Evalue=3e-61,
Organism=Homo sapiens, GI38679967, Length=509, Percent_Identity=31.041257367387, Blast_Score=234, Evalue=3e-61,
Organism=Homo sapiens, GI134142062, Length=507, Percent_Identity=29.7830374753452, Blast_Score=219, Evalue=1e-56,
Organism=Escherichia coli, GI1789654, Length=448, Percent_Identity=41.5178571428571, Blast_Score=322, Evalue=7e-89,
Organism=Escherichia coli, GI1786930, Length=327, Percent_Identity=32.4159021406728, Blast_Score=132, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI71987519, Length=440, Percent_Identity=49.7727272727273, Blast_Score=397, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17567343, Length=446, Percent_Identity=44.6188340807175, Blast_Score=357, Evalue=2e-98,
Organism=Caenorhabditis elegans, GI17562816, Length=453, Percent_Identity=43.046357615894, Blast_Score=330, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI133931226, Length=492, Percent_Identity=28.8617886178862, Blast_Score=195, Evalue=1e-49,
Organism=Caenorhabditis elegans, GI71997168, Length=508, Percent_Identity=27.755905511811, Blast_Score=193, Evalue=4e-49,
Organism=Caenorhabditis elegans, GI71997163, Length=508, Percent_Identity=27.755905511811, Blast_Score=193, Evalue=5e-49,
Organism=Saccharomyces cerevisiae, GI6319685, Length=1214, Percent_Identity=51.9769357495881, Blast_Score=1277, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319695, Length=448, Percent_Identity=39.0625, Blast_Score=293, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6321376, Length=448, Percent_Identity=39.9553571428571, Blast_Score=285, Evalue=3e-77,
Organism=Saccharomyces cerevisiae, GI6323863, Length=466, Percent_Identity=32.8326180257511, Blast_Score=242, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6324343, Length=513, Percent_Identity=30.6042884990253, Blast_Score=231, Evalue=8e-61,
Organism=Drosophila melanogaster, GI24651757, Length=452, Percent_Identity=47.5663716814159, Blast_Score=401, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24651759, Length=416, Percent_Identity=45.9134615384615, Blast_Score=356, Evalue=6e-98,
Organism=Drosophila melanogaster, GI281363050, Length=451, Percent_Identity=39.9113082039911, Blast_Score=308, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24652224, Length=451, Percent_Identity=39.9113082039911, Blast_Score=308, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24652222, Length=451, Percent_Identity=39.9113082039911, Blast_Score=308, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24652220, Length=451, Percent_Identity=39.9113082039911, Blast_Score=308, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24652218, Length=451, Percent_Identity=39.9113082039911, Blast_Score=308, Evalue=1e-83,
Organism=Drosophila melanogaster, GI24652212, Length=451, Percent_Identity=39.9113082039911, Blast_Score=308, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24652210, Length=451, Percent_Identity=39.9113082039911, Blast_Score=308, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24652214, Length=451, Percent_Identity=39.9113082039911, Blast_Score=308, Evalue=2e-83,
Organism=Drosophila melanogaster, GI19921944, Length=451, Percent_Identity=39.9113082039911, Blast_Score=308, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24652216, Length=451, Percent_Identity=39.9113082039911, Blast_Score=308, Evalue=2e-83,
Organism=Drosophila melanogaster, GI161076409, Length=503, Percent_Identity=29.6222664015905, Blast_Score=214, Evalue=4e-55,
Organism=Drosophila melanogaster, GI161076407, Length=503, Percent_Identity=29.6222664015905, Blast_Score=214, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24586460, Length=503, Percent_Identity=29.6222664015905, Blast_Score=214, Evalue=4e-55,
Organism=Drosophila melanogaster, GI24586458, Length=503, Percent_Identity=29.6222664015905, Blast_Score=213, Evalue=5e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR011764
- InterPro:   IPR005482
- InterPro:   IPR005479
- InterPro:   IPR005481
- InterPro:   IPR013817
- InterPro:   IPR016185
- InterPro:   IPR011054 [H]

Pfam domain/function: PF02785 Biotin_carb_C; PF00289 CPSase_L_chain; PF02786 CPSase_L_D2 [H]

EC number: =6.3.4.14; =6.4.1.2 [H]

Molecular weight: Translated: 131835; Mature: 131835

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: PS50975 ATP_GRASP ; PS00866 CPSASE_1 ; PS00867 CPSASE_2 ; PS50979 BC ; PS50968 BIOTINYL_LIPOYL ; PS00188 BIOTIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKKILIANRGEIAVRIARTLKKMGVTSVAVYSDADHDSLHVSVADEAVALNSGGSSSAA
CCCEEEEECCCCEEHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCEEEECCCCCCHHH
ETYLRGDRILEIARKTGAGAVIPGYGFLSENTTFAEQCAEAGVVFVGPTPEQVRRFGLKH
HHHHCCHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHCCEEEECCCHHHHHHHHHHH
TARAIAEAAGVPLTPGTGLLQSLDDAKVAAQHIGYPVMLKSTAGGGGIGLSRCDNAAELA
HHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCHHHHH
TAYDSVQRLGQNFFKDSGVFIEGFVANARHVEVQIFGDGKGRVVALGERDCSLQRRHQKV
HHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCCCEEEECCCCCHHHHHHHHH
VEETPAPHLPDATRAALLDAAVKLGEAVNYVSAGTVEFIYDAARDAFYFLEVNTRLQVEH
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEECCEEEECC
PITEAVTGLDLVEWMVRIAAGEPPSFDDLPTPRGTAIEVRVYAENPVRGFQPAPGILTDV
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEECC
QFPEDVRVDTWVQTGTEVSANYDPLIAKVIAYGAHREEARQKLLMALELTRLHGSATNLD
CCCCCCCEEHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHH
YLRSILQSREFSAGTVSTLLLDRYDYVSPVVEVLESGTYTTVQDYPGRTGYWDIGVPPSG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCC
PMDDYAFRLANRIVGNHESAAGLECTLQGPTLKFHGDAVIALTGAPALATLDDGEPLPWW
CCHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCCEEEEEECCCEEEECCCCCCCCCC
KPIAVRASQVLRIAKASSGCRSYIAIRRGIDVPEYLGSKSTFVLGQFGGHAGRTLRVGDV
CHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHCCCCEEEEEECCCCCCCEEEECCC
LPISRPELAVCTTPAPACVPATPPHELVPSYGKHWDIGVLYGPHGAPDFFSEDSIARFFT
CCCCCCCEEEECCCCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEE
TDYQVHYNSNRLGVRLVGPKPKWTRSDGGEAGLHPSNVHDCVYAIGSINFTGDTPVILTC
EEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCEEECCCCCEEEEE
DGPSLGGFVCPATIAKAELWKVGQVKPGDTIRFRRMGFDEALALEQAQDKAIRLLRPLPD
CCCCCCCEECCHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
LSARDLPAAPATVSECVLAELPAEGQRPAVAYRQAGDKYILLEYGPNVLDLRLRLRVHLL
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHCCCEEEEEEECCCEEEHHHHHHHHHH
MEALKAAKLDGVHELSPGVRSVQIHYDSRVIAQSVLVERLIALETQLPGVEGLQVPSRIV
HHHHHHHHCCCHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHE
HLPMAFEDSATLGAVTRYIETVKADAPWLPNNVDFIQRINGLSRREDVRTTVFEASYMVM
EECEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHEEEEE
GLGDVYLGAPCAVPLDPRHRLLTSKYNPARTFTAEGTVGIGGVYMCIYGMDSPGGYQLVG
ECCCHHCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEECCCCCCEEEEC
RTVPIWNKFLRNRQFGAEPWLLRFFDRVRFYPVTEVELDQFRADFRAGRTHIKVEDAVFD
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCEEEEEHHHHHH
LAEHERLLAQDASSIEAFRERQQTAYATEVALWQNDPKVEAVEDAEEAVMQAVDGSAVVA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEH
DMWGNVWKVLVDVGQEVQIGEPLVILEAMKMEFQVAASQAGTIAALHCKAGKPVAAGDAL
HHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCEECCCEE
VVIRPHPVAATVPYA
EEECCCCCEECCCCC
>Mature Secondary Structure
MFKKILIANRGEIAVRIARTLKKMGVTSVAVYSDADHDSLHVSVADEAVALNSGGSSSAA
CCCEEEEECCCCEEHHHHHHHHHCCCCEEEEEECCCCCEEEEEECCCEEEECCCCCCHHH
ETYLRGDRILEIARKTGAGAVIPGYGFLSENTTFAEQCAEAGVVFVGPTPEQVRRFGLKH
HHHHCCHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHCCEEEECCCHHHHHHHHHHH
TARAIAEAAGVPLTPGTGLLQSLDDAKVAAQHIGYPVMLKSTAGGGGIGLSRCDNAAELA
HHHHHHHHCCCCCCCCCHHHHHCHHHHHHHHHCCCEEEEEECCCCCCCCHHHCCCHHHHH
TAYDSVQRLGQNFFKDSGVFIEGFVANARHVEVQIFGDGKGRVVALGERDCSLQRRHQKV
HHHHHHHHHHHHHHCCCCCEEEEEECCCEEEEEEEEECCCCCEEEECCCCCHHHHHHHHH
VEETPAPHLPDATRAALLDAAVKLGEAVNYVSAGTVEFIYDAARDAFYFLEVNTRLQVEH
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEEEEECCEEEECC
PITEAVTGLDLVEWMVRIAAGEPPSFDDLPTPRGTAIEVRVYAENPVRGFQPAPGILTDV
CHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCEECC
QFPEDVRVDTWVQTGTEVSANYDPLIAKVIAYGAHREEARQKLLMALELTRLHGSATNLD
CCCCCCCEEHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCHH
YLRSILQSREFSAGTVSTLLLDRYDYVSPVVEVLESGTYTTVQDYPGRTGYWDIGVPPSG
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCC
PMDDYAFRLANRIVGNHESAAGLECTLQGPTLKFHGDAVIALTGAPALATLDDGEPLPWW
CCHHHHHHHHHHHHCCCCCCCCEEEEEECCEEEECCCEEEEEECCCEEEECCCCCCCCCC
KPIAVRASQVLRIAKASSGCRSYIAIRRGIDVPEYLGSKSTFVLGQFGGHAGRTLRVGDV
CHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCHHHHCCCCEEEEEECCCCCCCEEEECCC
LPISRPELAVCTTPAPACVPATPPHELVPSYGKHWDIGVLYGPHGAPDFFSEDSIARFFT
CCCCCCCEEEECCCCCCCCCCCCCHHHCCCCCCCEEEEEEECCCCCCCCCCCCCEEEEEE
TDYQVHYNSNRLGVRLVGPKPKWTRSDGGEAGLHPSNVHDCVYAIGSINFTGDTPVILTC
EEEEEEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCEEECCCCCEEEEE
DGPSLGGFVCPATIAKAELWKVGQVKPGDTIRFRRMGFDEALALEQAQDKAIRLLRPLPD
CCCCCCCEECCHHHHHHHHHCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
LSARDLPAAPATVSECVLAELPAEGQRPAVAYRQAGDKYILLEYGPNVLDLRLRLRVHLL
CCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHCCCEEEEEEECCCEEEHHHHHHHHHH
MEALKAAKLDGVHELSPGVRSVQIHYDSRVIAQSVLVERLIALETQLPGVEGLQVPSRIV
HHHHHHHHCCCHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHE
HLPMAFEDSATLGAVTRYIETVKADAPWLPNNVDFIQRINGLSRREDVRTTVFEASYMVM
EECEECCCCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHEEEEE
GLGDVYLGAPCAVPLDPRHRLLTSKYNPARTFTAEGTVGIGGVYMCIYGMDSPGGYQLVG
ECCCHHCCCCCCCCCCCHHHHHHCCCCCCEEEECCCCCCCCEEEEEEEECCCCCCEEEEC
RTVPIWNKFLRNRQFGAEPWLLRFFDRVRFYPVTEVELDQFRADFRAGRTHIKVEDAVFD
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHEECCCCCHHHHHHHHHHCCCEEEEEHHHHHH
LAEHERLLAQDASSIEAFRERQQTAYATEVALWQNDPKVEAVEDAEEAVMQAVDGSAVVA
HHHHHHHHHHCHHHHHHHHHHHHHHHHHEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEH
DMWGNVWKVLVDVGQEVQIGEPLVILEAMKMEFQVAASQAGTIAALHCKAGKPVAAGDAL
HHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCEEEEEECCCCCEECCCEE
VVIRPHPVAATVPYA
EEECCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]