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The map label for this gene is uahA [H]

Identifier: 21245039

GI number: 21245039

Start: 5114835

End: 5116634

Strand: Reverse

Name: uahA [H]

Synonym: XAC4327

Alternate gene names: 21245039

Gene position: 5116634-5114835 (Counterclockwise)

Preceding gene: 21245040

Following gene: 21245038

Centisome position: 98.86

GC content: 67.17

Gene sequence:

>1800_bases
ATGACCCACACCGCTTTTTGGACCTTGGCCGATTGGCAATCCGCGTATGCGCAGGGCGCCGCTCCTGCCGAACTGCTGTC
TTGCCTCATCGCCGGCTTGCCGCAAGGTGATGTCGCCTGGATTTCCCGGCTTTCCCTGGACGGCCTGCAGTCCCGGCTTG
CCGGACTTGCCCAACAACTGATGCAGGTTGGCGGCGACCTGTCTAGGCTGCCGCTCTATGGCGTGCCCTTCGCCGCGAAG
GACAACATCGATGTCGCGGGGTTGCCTACGACCTGCGCCTGCCCGGAGTTCGCCTACCAGCCGACACACAACGCCGCCGT
GATCGATCGGCTTGAAGCCGCTGGCGCGGTGGTCATCGGTAAGACCAACCTTGACCAGTTCGCCACCGGCCTGGTGGGCA
CGCGCTCGCCCTATGGCCCGGTGCCCAATGCCTTCAAAGCCGAGTACATCAGTGGTGGATCCAGCTCGGGCTCGGCCTCC
GTGGTGGCTCGTGGTCTCGTGCCGTTTGCGCTGGGGACCGATACCGCCGGCTCCGGCCGCGTGCCGGCCGGCCACAACAA
CCTGGTAGGCCTGAAGCCTACACGCGGAATGGTCAGCAACCGCGGACTGGTGCCTGCCTGCCGCACGCTGGATTGCATCA
CGGTGCTGGCACTGAGCGTAGACGACGCCGATGCAGCGCTGCGCGCGATGGGCGGCTTCGATGCCTCCGATGCGTATTCG
CGTCAGGCACCGGTCCGTCCTGCCAGCTGGCCCGCCAAGCCGGTGCTGGGCATTCCCGCCTCGCCCGACTGGTTTGGCGA
TATCCAGGCCGAGCGCGTCTACACCGATGCGCTGCGACGGTTGGAAACCATCGGCGTGGAACTGGAGCTGATCGACTTCG
CGCCGCTGTTCGAGGTCGCTGCGCTGCTCTACGAAGGCCCCTGGGTGGGCGAACGCTACGCCGCCATTGAGGAGCTGATG
AACGCCAAGCCAGAAGTCGTGCACCCGGTGGTGCGCGCCATCGTTCAAAAGGCGACGAACTTCAGCGCGGTGGACGCCTA
CAAGGCCGAGTACCGCCGCATGGCGCTGGCACGCAAGGCCGAAGCGCTGATGCAGGGCCTCGACGGCCTGCTGGTGCCCA
CCGCGCCCAGCATCTACACCATTGAGCAGTTGCTGGCCGACCCGGTGACGATGAACGCGCGCATGGGCGTCTACACAAAC
TTCGTGAACCTACTCGACTTTAGCGCCATTGCGCTGCCGGCTGGCATGCGCGCCGATGGGTTGCCGGCAGGCATCACGCT
GATCGCACCGGCTTGGCACGAGGCGCGGCTGATCGCGTTCGGCCGGCGCTGGCAGGCGGCAGCGCCCTGGAAGCGCGGTG
CTTCGCAGCAGGAGCTGCCACCGGTCGATGTGCCAGCCGCCCCAAGCCTCGATGGCCACGTCATCGTCGCGGTCGTCGGC
GCGCACCTATCGGGCATGCCTCTGAACGGGCAGCTCACCGAGCGCGGCGCCACGCTGCTGGAGAGCACGCACACCTCGGC
GGCGTATCGCCTCTATGCCTTGCCCGGGACCGTGCCGCCCAAGCCGGGGATGCTGCGCACGGGCGAAGGCGCGCCCATCG
CGGTCGAACTGTGGGCCATGCCGGTCGAGCGCTACGGCTCCTTCGTCGCCTTGATCCCATCGCCCTTGGGGATCGGCAGC
CTGGATCTGATCGATGGCCGCACGGTCCAGGGTTTCATCTGCGAGTCCTGGGCCACGCGGGGGGCGGAGGACATCACCGC
GCTAGGCGGTTGGCGTGCTTACGTGGCCCGGAAGAACTAG

Upstream 100 bases:

>100_bases
ATCACATCAAGAATTCTCAGATGGATATCAGTTGCTGGAGTCGACCAGTCGCCGCGCATGCCGGGGAGCTTCCCGCGGTC
ATCCAACTTGTCGAGCGACC

Downstream 100 bases:

>100_bases
GCCATCGCGCCCGAACTTCACCTACCCATTCGCAGTGGGCTCCGGTCGGAGGCCAAGCCGCTGCATCGCCCGGAGCACGC
CATATGTTCAAGAAAATCCT

Product: allophanate hydrolase

Products: NA

Alternate protein names: Glu-ADT subunit A [H]

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MTHTAFWTLADWQSAYAQGAAPAELLSCLIAGLPQGDVAWISRLSLDGLQSRLAGLAQQLMQVGGDLSRLPLYGVPFAAK
DNIDVAGLPTTCACPEFAYQPTHNAAVIDRLEAAGAVVIGKTNLDQFATGLVGTRSPYGPVPNAFKAEYISGGSSSGSAS
VVARGLVPFALGTDTAGSGRVPAGHNNLVGLKPTRGMVSNRGLVPACRTLDCITVLALSVDDADAALRAMGGFDASDAYS
RQAPVRPASWPAKPVLGIPASPDWFGDIQAERVYTDALRRLETIGVELELIDFAPLFEVAALLYEGPWVGERYAAIEELM
NAKPEVVHPVVRAIVQKATNFSAVDAYKAEYRRMALARKAEALMQGLDGLLVPTAPSIYTIEQLLADPVTMNARMGVYTN
FVNLLDFSAIALPAGMRADGLPAGITLIAPAWHEARLIAFGRRWQAAAPWKRGASQQELPPVDVPAAPSLDGHVIVAVVG
AHLSGMPLNGQLTERGATLLESTHTSAAYRLYALPGTVPPKPGMLRTGEGAPIAVELWAMPVERYGSFVALIPSPLGIGS
LDLIDGRTVQGFICESWATRGAEDITALGGWRAYVARKN

Sequences:

>Translated_599_residues
MTHTAFWTLADWQSAYAQGAAPAELLSCLIAGLPQGDVAWISRLSLDGLQSRLAGLAQQLMQVGGDLSRLPLYGVPFAAK
DNIDVAGLPTTCACPEFAYQPTHNAAVIDRLEAAGAVVIGKTNLDQFATGLVGTRSPYGPVPNAFKAEYISGGSSSGSAS
VVARGLVPFALGTDTAGSGRVPAGHNNLVGLKPTRGMVSNRGLVPACRTLDCITVLALSVDDADAALRAMGGFDASDAYS
RQAPVRPASWPAKPVLGIPASPDWFGDIQAERVYTDALRRLETIGVELELIDFAPLFEVAALLYEGPWVGERYAAIEELM
NAKPEVVHPVVRAIVQKATNFSAVDAYKAEYRRMALARKAEALMQGLDGLLVPTAPSIYTIEQLLADPVTMNARMGVYTN
FVNLLDFSAIALPAGMRADGLPAGITLIAPAWHEARLIAFGRRWQAAAPWKRGASQQELPPVDVPAAPSLDGHVIVAVVG
AHLSGMPLNGQLTERGATLLESTHTSAAYRLYALPGTVPPKPGMLRTGEGAPIAVELWAMPVERYGSFVALIPSPLGIGS
LDLIDGRTVQGFICESWATRGAEDITALGGWRAYVARKN
>Mature_598_residues
THTAFWTLADWQSAYAQGAAPAELLSCLIAGLPQGDVAWISRLSLDGLQSRLAGLAQQLMQVGGDLSRLPLYGVPFAAKD
NIDVAGLPTTCACPEFAYQPTHNAAVIDRLEAAGAVVIGKTNLDQFATGLVGTRSPYGPVPNAFKAEYISGGSSSGSASV
VARGLVPFALGTDTAGSGRVPAGHNNLVGLKPTRGMVSNRGLVPACRTLDCITVLALSVDDADAALRAMGGFDASDAYSR
QAPVRPASWPAKPVLGIPASPDWFGDIQAERVYTDALRRLETIGVELELIDFAPLFEVAALLYEGPWVGERYAAIEELMN
AKPEVVHPVVRAIVQKATNFSAVDAYKAEYRRMALARKAEALMQGLDGLLVPTAPSIYTIEQLLADPVTMNARMGVYTNF
VNLLDFSAIALPAGMRADGLPAGITLIAPAWHEARLIAFGRRWQAAAPWKRGASQQELPPVDVPAAPSLDGHVIVAVVGA
HLSGMPLNGQLTERGATLLESTHTSAAYRLYALPGTVPPKPGMLRTGEGAPIAVELWAMPVERYGSFVALIPSPLGIGSL
DLIDGRTVQGFICESWATRGAEDITALGGWRAYVARKN

Specific function: Furnishes a means for formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu- tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activa

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amidase family [H]

Homologues:

Organism=Homo sapiens, GI222831590, Length=435, Percent_Identity=29.8850574712644, Blast_Score=144, Evalue=2e-34,
Organism=Homo sapiens, GI195972892, Length=171, Percent_Identity=29.2397660818713, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17543272, Length=400, Percent_Identity=28.25, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17537465, Length=416, Percent_Identity=28.3653846153846, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17556264, Length=236, Percent_Identity=27.9661016949153, Blast_Score=79, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17538252, Length=133, Percent_Identity=28.5714285714286, Blast_Score=69, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6319685, Length=609, Percent_Identity=44.4991789819376, Blast_Score=488, Evalue=1e-138,
Organism=Saccharomyces cerevisiae, GI6323950, Length=227, Percent_Identity=33.920704845815, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24648113, Length=461, Percent_Identity=29.0672451193059, Blast_Score=113, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21356731, Length=138, Percent_Identity=34.7826086956522, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24652985, Length=401, Percent_Identity=24.9376558603491, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI19922090, Length=401, Percent_Identity=24.9376558603491, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24652981, Length=401, Percent_Identity=24.9376558603491, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24652983, Length=401, Percent_Identity=24.9376558603491, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000120
- InterPro:   IPR020556
- InterPro:   IPR004412 [H]

Pfam domain/function: PF01425 Amidase [H]

EC number: 6.3.5.-

Molecular weight: Translated: 63306; Mature: 63175

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTAFWTLADWQSAYAQGAAPAELLSCLIAGLPQGDVAWISRLSLDGLQSRLAGLAQQL
CCCEEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MQVGGDLSRLPLYGVPFAAKDNIDVAGLPTTCACPEFAYQPTHNAAVIDRLEAAGAVVIG
HHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEE
KTNLDQFATGLVGTRSPYGPVPNAFKAEYISGGSSSGSASVVARGLVPFALGTDTAGSGR
CCCHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHCCEEEEECCCCCCCCC
VPAGHNNLVGLKPTRGMVSNRGLVPACRTLDCITVLALSVDDADAALRAMGGFDASDAYS
CCCCCCCEEECCCCCCHHCCCCCCCHHHHHHEEHHEEEECCCHHHHHHHHCCCCCCCCCC
RQAPVRPASWPAKPVLGIPASPDWFGDIQAERVYTDALRRLETIGVELELIDFAPLFEVA
CCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHH
ALLYEGPWVGERYAAIEELMNAKPEVVHPVVRAIVQKATNFSAVDAYKAEYRRMALARKA
HHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EALMQGLDGLLVPTAPSIYTIEQLLADPVTMNARMGVYTNFVNLLDFSAIALPAGMRADG
HHHHHCCCCEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
LPAGITLIAPAWHEARLIAFGRRWQAAAPWKRGASQQELPPVDVPAAPSLDGHVIVAVVG
CCCCEEEEECCCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
AHLSGMPLNGQLTERGATLLESTHTSAAYRLYALPGTVPPKPGMLRTGEGAPIAVELWAM
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCCCCEEEEEEEC
PVERYGSFVALIPSPLGIGSLDLIDGRTVQGFICESWATRGAEDITALGGWRAYVARKN
CHHHCCCEEEECCCCCCCCCEEEECCCCEEHHHHHHHHCCCCHHHHHHCCEEEEEEECC
>Mature Secondary Structure 
THTAFWTLADWQSAYAQGAAPAELLSCLIAGLPQGDVAWISRLSLDGLQSRLAGLAQQL
CCEEEEEHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
MQVGGDLSRLPLYGVPFAAKDNIDVAGLPTTCACPEFAYQPTHNAAVIDRLEAAGAVVIG
HHHCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCEEEEE
KTNLDQFATGLVGTRSPYGPVPNAFKAEYISGGSSSGSASVVARGLVPFALGTDTAGSGR
CCCHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHCCEEEEECCCCCCCCC
VPAGHNNLVGLKPTRGMVSNRGLVPACRTLDCITVLALSVDDADAALRAMGGFDASDAYS
CCCCCCCEEECCCCCCHHCCCCCCCHHHHHHEEHHEEEECCCHHHHHHHHCCCCCCCCCC
RQAPVRPASWPAKPVLGIPASPDWFGDIQAERVYTDALRRLETIGVELELIDFAPLFEVA
CCCCCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHH
ALLYEGPWVGERYAAIEELMNAKPEVVHPVVRAIVQKATNFSAVDAYKAEYRRMALARKA
HHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
EALMQGLDGLLVPTAPSIYTIEQLLADPVTMNARMGVYTNFVNLLDFSAIALPAGMRADG
HHHHHCCCCEECCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
LPAGITLIAPAWHEARLIAFGRRWQAAAPWKRGASQQELPPVDVPAAPSLDGHVIVAVVG
CCCCEEEEECCCCCEEEEEECCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEC
AHLSGMPLNGQLTERGATLLESTHTSAAYRLYALPGTVPPKPGMLRTGEGAPIAVELWAM
CCCCCCCCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCEEECCCCCCEEEEEEEC
PVERYGSFVALIPSPLGIGSLDLIDGRTVQGFICESWATRGAEDITALGGWRAYVARKN
CHHHCCCEEEECCCCCCCCCEEEECCCCEEHHHHHHHHCCCCHHHHHHCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA