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The map label for this gene is comM [H]

Identifier: 21244650

GI number: 21244650

Start: 4623041

End: 4624111

Strand: Direct

Name: comM [H]

Synonym: XAC3931

Alternate gene names: 21244650

Gene position: 4623041-4624111 (Clockwise)

Preceding gene: 21244649

Following gene: 21244651

Centisome position: 89.32

GC content: 69.28

Gene sequence:

>1071_bases
ATGAGTCTGGCGCTGGTGCACAGCCGTGCCCGCGTGGGGGTGCATGCGCCTGAGGTTCGGGTGGAAGTGCATCTCTCCGG
CGGGCTTCCCTCTACCCAGATCGTGGGCCTGCCCGAAGCGGCAGTGCGCGAATCGCGCGAGCGCGTACGCGCTGCCCTGC
TATGCGCACAGTTCGAATTCCCCGCCCGGCGCATCACCATCAACCTGGCACCGGCTGATCTACCGAAAGAAGGCGGCCGG
TTCGATCTGCCGATCGCCCTCGGCATCCTGGCTGCCAGCGGGCAGATCGACCGCCAGGCCCTGGCCGATTACGAATTCCT
CGGCGAGCTTGCGCTTACCGGCGAGCTGCGTGGTGTCGACGGCGTGCTGCCCGCGGCGCTGGCGGCCGCGCAGGCCGGGC
GACGGCTGATCGTCCCGCTCGCCAACGGTGCCGAAGCCGCCATCGCCGGGCACGTCGAAGCCTTCACCGCGCGCACCCTG
CTGGAGGTCTGCGCCACGCTCAACGGCAGCCAGAAAGCGCCCGCCGCCGAGCTGGCAGTGCAGGCGCTCGGCGCACGCGC
CCTGCCCGATATGGCCGACGTGCGCGGGCAACCGCACGCACGTCGCGCGCTGGAAATCGCCGCTGCCGGTGGGCACCATC
TGTTGCTGGTCGGCAGCCCCGGTTGCGGCAAGACGCTGCTGGCTTCGCGCCTGCCTGGTCTATTGCCCGAAGCCAGCGAA
GCAGAAGCACTGGAAACCGCTGCAATCACCTCGATCAGCGGCCGTGGGCTGGATCTGGCCCGCTGGCGGCAACGGCCGTA
CCGCGCCCCGCATCACACCGCCAGCGCAGTGGCCCTGGTCGGCGGCGGCACGCATCCGCGCCCCGGCGAGATCTCGCTGT
CTCACAACGGCGTGCTGTTCCTGGACGAATTGCCCGAATGGCAACGGCAAACCCTGGAAGTCTTGCGCGAGCCCTTGGAG
TCGGGCGTGGTCACGATCGCGCGCGCGGCGCGCAGCGTGGATTTTCCGGCGCGCTTTCAATTGGTCGCCGCCATGAATCC
CTGCCCGTGCACACGTAACATGCCGTGCTAA

Upstream 100 bases:

>100_bases
CGACGCACTGGAGCAGGCCGTCGCCGCACTGGAAACACGCGCCCCCGGCGCGCCGCCTGCCGCACCTCCCACCACCACCA
CCTGAGCGAAGGCCACCACC

Downstream 100 bases:

>100_bases
GATCGTCAATGTAACGACAATAGAGTGGACATATGGCGTCCTTGGAACTAGTGAAGCTAGCCAGCCTCCTCCCGGCGATC
ACTGATGAAAAGGTATCTTG

Product: competence-like protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 356; Mature: 355

Protein sequence:

>356_residues
MSLALVHSRARVGVHAPEVRVEVHLSGGLPSTQIVGLPEAAVRESRERVRAALLCAQFEFPARRITINLAPADLPKEGGR
FDLPIALGILAASGQIDRQALADYEFLGELALTGELRGVDGVLPAALAAAQAGRRLIVPLANGAEAAIAGHVEAFTARTL
LEVCATLNGSQKAPAAELAVQALGARALPDMADVRGQPHARRALEIAAAGGHHLLLVGSPGCGKTLLASRLPGLLPEASE
AEALETAAITSISGRGLDLARWRQRPYRAPHHTASAVALVGGGTHPRPGEISLSHNGVLFLDELPEWQRQTLEVLREPLE
SGVVTIARAARSVDFPARFQLVAAMNPCPCTRNMPC

Sequences:

>Translated_356_residues
MSLALVHSRARVGVHAPEVRVEVHLSGGLPSTQIVGLPEAAVRESRERVRAALLCAQFEFPARRITINLAPADLPKEGGR
FDLPIALGILAASGQIDRQALADYEFLGELALTGELRGVDGVLPAALAAAQAGRRLIVPLANGAEAAIAGHVEAFTARTL
LEVCATLNGSQKAPAAELAVQALGARALPDMADVRGQPHARRALEIAAAGGHHLLLVGSPGCGKTLLASRLPGLLPEASE
AEALETAAITSISGRGLDLARWRQRPYRAPHHTASAVALVGGGTHPRPGEISLSHNGVLFLDELPEWQRQTLEVLREPLE
SGVVTIARAARSVDFPARFQLVAAMNPCPCTRNMPC
>Mature_355_residues
SLALVHSRARVGVHAPEVRVEVHLSGGLPSTQIVGLPEAAVRESRERVRAALLCAQFEFPARRITINLAPADLPKEGGRF
DLPIALGILAASGQIDRQALADYEFLGELALTGELRGVDGVLPAALAAAQAGRRLIVPLANGAEAAIAGHVEAFTARTLL
EVCATLNGSQKAPAAELAVQALGARALPDMADVRGQPHARRALEIAAAGGHHLLLVGSPGCGKTLLASRLPGLLPEASEA
EALETAAITSISGRGLDLARWRQRPYRAPHHTASAVALVGGGTHPRPGEISLSHNGVLFLDELPEWQRQTLEVLREPLES
GVVTIARAARSVDFPARFQLVAAMNPCPCTRNMPC

Specific function: Induced during competence development. Not needed for DNA uptake. May be involved in a recombination step [H]

COG id: COG0606

COG function: function code O; Predicted ATPase with chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Mg-chelatase subunits D/I family. ComM subfamily [H]

Homologues:

Organism=Escherichia coli, GI145693202, Length=353, Percent_Identity=55.2407932011331, Blast_Score=377, Evalue=1e-106,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR001208
- InterPro:   IPR004482
- InterPro:   IPR000523
- InterPro:   IPR020568 [H]

Pfam domain/function: PF01078 Mg_chelatase [H]

EC number: NA

Molecular weight: Translated: 37397; Mature: 37265

Theoretical pI: Translated: 7.61; Mature: 7.61

Prosite motif: PS00626 RCC1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLALVHSRARVGVHAPEVRVEVHLSGGLPSTQIVGLPEAAVRESRERVRAALLCAQFEF
CCEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCC
PARRITINLAPADLPKEGGRFDLPIALGILAASGQIDRQALADYEFLGELALTGELRGVD
CCEEEEEEECCCCCCCCCCCEECHHHEEEECCCCCCCHHHHHHHHHHHHHHEECCCCCCC
GVLPAALAAAQAGRRLIVPLANGAEAAIAGHVEAFTARTLLEVCATLNGSQKAPAAELAV
CHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
QALGARALPDMADVRGQPHARRALEIAAAGGHHLLLVGSPGCGKTLLASRLPGLLPEASE
HHHCCCCCCCHHHHCCCCCHHHHEEEEECCCCEEEEEECCCCCHHHHHHHCCCCCCCCCH
AEALETAAITSISGRGLDLARWRQRPYRAPHHTASAVALVGGGTHPRPGEISLSHNGVLF
HHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCEEE
LDELPEWQRQTLEVLREPLESGVVTIARAARSVDFPARFQLVAAMNPCPCTRNMPC
ECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
SLALVHSRARVGVHAPEVRVEVHLSGGLPSTQIVGLPEAAVRESRERVRAALLCAQFEF
CEEEEECCCCCCCCCCCEEEEEEECCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHCCC
PARRITINLAPADLPKEGGRFDLPIALGILAASGQIDRQALADYEFLGELALTGELRGVD
CCEEEEEEECCCCCCCCCCCEECHHHEEEECCCCCCCHHHHHHHHHHHHHHEECCCCCCC
GVLPAALAAAQAGRRLIVPLANGAEAAIAGHVEAFTARTLLEVCATLNGSQKAPAAELAV
CHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
QALGARALPDMADVRGQPHARRALEIAAAGGHHLLLVGSPGCGKTLLASRLPGLLPEASE
HHHCCCCCCCHHHHCCCCCHHHHEEEEECCCCEEEEEECCCCCHHHHHHHCCCCCCCCCH
AEALETAAITSISGRGLDLARWRQRPYRAPHHTASAVALVGGGTHPRPGEISLSHNGVLF
HHHHHHHHHHCCCCCCCCHHHHHCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCEEE
LDELPEWQRQTLEVLREPLESGVVTIARAARSVDFPARFQLVAAMNPCPCTRNMPC
ECCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800; 9457884 [H]