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The map label for this gene is dpm1 [H]

Identifier: 21244628

GI number: 21244628

Start: 4594482

End: 4595288

Strand: Direct

Name: dpm1 [H]

Synonym: XAC3909

Alternate gene names: 21244628

Gene position: 4594482-4595288 (Clockwise)

Preceding gene: 21244627

Following gene: 21244629

Centisome position: 88.77

GC content: 65.18

Gene sequence:

>807_bases
GTGCATGCTTCATGCCTGACTCAGAGAGTCAGGGCACAATGCCCGATCTTTTTCGCTCAGCCTTCATCCGGCCACCCTGC
AACCATGAGCCAACCTCAGCTGTCCGTCGTCGTCCCGGTATTCAACGAGCGCGATAACGTCGCCACGCTGGTGGGCGAAA
TCGTCAGCGCCCTGCGCGGCGTGGTGGCCTTCGAAATCGTGTATGTCGACGACCATTCGCGCGACGACACGCTCGCAGTG
CTGCAAGGCCTGAAGAGCACCACACCGGAACTGCGCGTGCTGCATCATGTGACCCAGAGCGGCCAGAGCACGGCGGTGCG
CAGCGGGGTGAAGGCCGCGCGCGCCAGCTGGATCGCCACGCTCGATGGCGACGGCCAGAACGACCCGGCCGACATCCCCA
AGCTGCTGATCGCGCGCAGCCAGGCGCAGGCGCAGGTGAAGCTGTTCGCCGGCTGGCGGGTCAATCGCCAGGATTCTGGC
TCCAAGCGCTGGGCCAGCAAATGGGCCAATGCGATCCGCTCGCGCATGCTGCGCGACAATACGCCCGACACCGGCTGCGG
CATCAAGCTGTTCGAGCGCGAGGCATTTCTGGACCTGCCCTACTTCGACCACATGCACCGCTATTTGCCGGCGTTGATGC
AGCGCGCCGGCTGGCGCACGGTGAGCGTGCCGGTCAACCATCGCCACCGCACCGCCGGCGTGTCCAAGTACAACAATCTC
AATCGCGCCCTGGTCGGCATCCGCGACCTGCTCGGTGTGGCCTGGCTGATCACCCGCAGCAAGCGCACAGTGGTGCAGGA
ACGCTGA

Upstream 100 bases:

>100_bases
ACGACGCGTGATCGGCCCGCTAGCCCAACACCTTCGCAGCCTTGCCACGTCCCCATCATTCACTACAGGCTGCTTCCAAC
CGGTCCAATGCGCATAACGC

Downstream 100 bases:

>100_bases
TGGACCCGTCCTTTCTCGACCAGCAACTGACCTGGCTGTACTGGACAGGCATCCATGTGACCGGGTGGAAGCTGATCGGC
TATGTCGGCGCGCTGATGTT

Product: dolichol-phosphate mannosyltransferase

Products: NA

Alternate protein names: Undecaprenyl-phosphate Ara4FN transferase; Ara4FN transferase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MHASCLTQRVRAQCPIFFAQPSSGHPATMSQPQLSVVVPVFNERDNVATLVGEIVSALRGVVAFEIVYVDDHSRDDTLAV
LQGLKSTTPELRVLHHVTQSGQSTAVRSGVKAARASWIATLDGDGQNDPADIPKLLIARSQAQAQVKLFAGWRVNRQDSG
SKRWASKWANAIRSRMLRDNTPDTGCGIKLFEREAFLDLPYFDHMHRYLPALMQRAGWRTVSVPVNHRHRTAGVSKYNNL
NRALVGIRDLLGVAWLITRSKRTVVQER

Sequences:

>Translated_268_residues
MHASCLTQRVRAQCPIFFAQPSSGHPATMSQPQLSVVVPVFNERDNVATLVGEIVSALRGVVAFEIVYVDDHSRDDTLAV
LQGLKSTTPELRVLHHVTQSGQSTAVRSGVKAARASWIATLDGDGQNDPADIPKLLIARSQAQAQVKLFAGWRVNRQDSG
SKRWASKWANAIRSRMLRDNTPDTGCGIKLFEREAFLDLPYFDHMHRYLPALMQRAGWRTVSVPVNHRHRTAGVSKYNNL
NRALVGIRDLLGVAWLITRSKRTVVQER
>Mature_268_residues
MHASCLTQRVRAQCPIFFAQPSSGHPATMSQPQLSVVVPVFNERDNVATLVGEIVSALRGVVAFEIVYVDDHSRDDTLAV
LQGLKSTTPELRVLHHVTQSGQSTAVRSGVKAARASWIATLDGDGQNDPADIPKLLIARSQAQAQVKLFAGWRVNRQDSG
SKRWASKWANAIRSRMLRDNTPDTGCGIKLFEREAFLDLPYFDHMHRYLPALMQRAGWRTVSVPVNHRHRTAGVSKYNNL
NRALVGIRDLLGVAWLITRSKRTVVQER

Specific function: Catalyzes the transfer of 4-deoxy-4-formamido-L- arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides [H]

COG id: COG0463

COG function: function code M; Glycosyltransferases involved in cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 2 family [H]

Homologues:

Organism=Escherichia coli, GI1788588, Length=208, Percent_Identity=27.8846153846154, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787259, Length=104, Percent_Identity=30.7692307692308, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788692, Length=225, Percent_Identity=26.2222222222222, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71999402, Length=222, Percent_Identity=25.6756756756757, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24585265, Length=232, Percent_Identity=24.5689655172414, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022857
- InterPro:   IPR001173 [H]

Pfam domain/function: PF00535 Glycos_transf_2 [H]

EC number: =2.7.8.30 [H]

Molecular weight: Translated: 29852; Mature: 29852

Theoretical pI: Translated: 10.89; Mature: 10.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHASCLTQRVRAQCPIFFAQPSSGHPATMSQPQLSVVVPVFNERDNVATLVGEIVSALRG
CCHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
VVAFEIVYVDDHSRDDTLAVLQGLKSTTPELRVLHHVTQSGQSTAVRSGVKAARASWIAT
HHEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEE
LDGDGQNDPADIPKLLIARSQAQAQVKLFAGWRVNRQDSGSKRWASKWANAIRSRMLRDN
ECCCCCCCHHHHHHHHHHHHHHHHEEEEEECEECCCCCCCHHHHHHHHHHHHHHHHHCCC
TPDTGCGIKLFEREAFLDLPYFDHMHRYLPALMQRAGWRTVSVPVNHRHRTAGVSKYNNL
CCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHCCHHHHHHH
NRALVGIRDLLGVAWLITRSKRTVVQER
HHHHHHHHHHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure
MHASCLTQRVRAQCPIFFAQPSSGHPATMSQPQLSVVVPVFNERDNVATLVGEIVSALRG
CCHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHH
VVAFEIVYVDDHSRDDTLAVLQGLKSTTPELRVLHHVTQSGQSTAVRSGVKAARASWIAT
HHEEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEEE
LDGDGQNDPADIPKLLIARSQAQAQVKLFAGWRVNRQDSGSKRWASKWANAIRSRMLRDN
ECCCCCCCHHHHHHHHHHHHHHHHEEEEEECEECCCCCCCHHHHHHHHHHHHHHHHHCCC
TPDTGCGIKLFEREAFLDLPYFDHMHRYLPALMQRAGWRTVSVPVNHRHRTAGVSKYNNL
CCCCCCCEEEEEHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHCCHHHHHHH
NRALVGIRDLLGVAWLITRSKRTVVQER
HHHHHHHHHHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12219091 [H]