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The map label for this gene is cox3 [H]

Identifier: 21244608

GI number: 21244608

Start: 4567385

End: 4568260

Strand: Reverse

Name: cox3 [H]

Synonym: XAC3884

Alternate gene names: 21244608

Gene position: 4568260-4567385 (Counterclockwise)

Preceding gene: 21244609

Following gene: 21244606

Centisome position: 88.27

GC content: 61.42

Gene sequence:

>876_bases
ATGGCCGATCACAGTCCCAACGCCGACGCGTATTTCGTCCCGAGCCAGAGCAAATGGCCCTTTGTCGGGTCGATTGCGAT
GTTCGTGATGATGATCGGCGTGGCCAGCTGGCTCAACGACGCCGCATGGGGGCGCTGGACCTTCTTCGCCGGCGTGGCGA
TGCTGCTGGCGACGTTGTTCATGTGGTTTGGCGATGTCATCCGCGAATCCAATGCCGGGCATTACAACCGCCAGGTGGAT
GGCTCGTTCCGCATGGGGATGGTGTGGTTCATCTTCTCCGAGGTGATGTTCTTCTGCGCGTTCTTCGGTGCGCTGTTCTA
CACGCGTGTGCTGACGCTGCCCTGGCTGGGCGGGGAAGGCGACGGCGTGATGACCAACGAACTGCTGTGGAATGGCTATT
CCGCTGCCTGGCCGACCAATGGCCCGGGCACGATCGGTGGGCAGTTCCAGACCATCCCGGCCTGGGGCCTGCCGCTGATC
AATACGCTGATCCTGCTCAGCTCCGGCGTGACCTTGACCATCGCCCACCACGCACTCAAGGGCGGGCGCCGTGGCGCGCT
CTTGTTATGGCTGGGGTTGACCGTGCTGCTGGGTTGCGTGTTCCTGTTCTTGCAGGCCGAGGAATACATCCACGCCTATA
CCGAGCTCAATCTCACGCTGGGCTCGGGCATCTACGGTTCGACGTTCTTCATGCTGACCGGCTTCCACGGCATGCACGTG
CTGCTGGGCACGATCATGTTGGCAGTGATGTGGCTGCGCGCGGCGAAAGGGCACTTCAGCCGCGACAATCACTTCGCTTT
CGAAGCGGCTGCGTGGTACTGGCACTTCGTCGACGTGGTGTGGCTGGCGCTGTTTTTGTTCGTGTATGTCCTTTGA

Upstream 100 bases:

>100_bases
ACGCGCTGACCTCGGAACTGCAGGGCGGCGGCACGTCTGCCGCGCCGCGCGCCGCACCCTGATTCTTCATCCACACGCAC
CACGACACGGAAGCAACGCC

Downstream 100 bases:

>100_bases
GAATCGGGAGTCGGGAATCGCCAGAGCGAGCCTGCTTTTGACTTTTACGATTCCCTACTCCCAATTCCCCTTTCCCGGCT
CCTCAGCGGCCGAGCCCATG

Product: cytochrome C oxidase subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III; Oxidase aa(3) subunit 3 [H]

Number of amino acids: Translated: 291; Mature: 290

Protein sequence:

>291_residues
MADHSPNADAYFVPSQSKWPFVGSIAMFVMMIGVASWLNDAAWGRWTFFAGVAMLLATLFMWFGDVIRESNAGHYNRQVD
GSFRMGMVWFIFSEVMFFCAFFGALFYTRVLTLPWLGGEGDGVMTNELLWNGYSAAWPTNGPGTIGGQFQTIPAWGLPLI
NTLILLSSGVTLTIAHHALKGGRRGALLLWLGLTVLLGCVFLFLQAEEYIHAYTELNLTLGSGIYGSTFFMLTGFHGMHV
LLGTIMLAVMWLRAAKGHFSRDNHFAFEAAAWYWHFVDVVWLALFLFVYVL

Sequences:

>Translated_291_residues
MADHSPNADAYFVPSQSKWPFVGSIAMFVMMIGVASWLNDAAWGRWTFFAGVAMLLATLFMWFGDVIRESNAGHYNRQVD
GSFRMGMVWFIFSEVMFFCAFFGALFYTRVLTLPWLGGEGDGVMTNELLWNGYSAAWPTNGPGTIGGQFQTIPAWGLPLI
NTLILLSSGVTLTIAHHALKGGRRGALLLWLGLTVLLGCVFLFLQAEEYIHAYTELNLTLGSGIYGSTFFMLTGFHGMHV
LLGTIMLAVMWLRAAKGHFSRDNHFAFEAAAWYWHFVDVVWLALFLFVYVL
>Mature_290_residues
ADHSPNADAYFVPSQSKWPFVGSIAMFVMMIGVASWLNDAAWGRWTFFAGVAMLLATLFMWFGDVIRESNAGHYNRQVDG
SFRMGMVWFIFSEVMFFCAFFGALFYTRVLTLPWLGGEGDGVMTNELLWNGYSAAWPTNGPGTIGGQFQTIPAWGLPLIN
TLILLSSGVTLTIAHHALKGGRRGALLLWLGLTVLLGCVFLFLQAEEYIHAYTELNLTLGSGIYGSTFFMLTGFHGMHVL
LGTIMLAVMWLRAAKGHFSRDNHFAFEAAAWYWHFVDVVWLALFLFVYVL

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=284, Percent_Identity=38.3802816901408, Blast_Score=171, Evalue=7e-43,
Organism=Escherichia coli, GI1786633, Length=170, Percent_Identity=30.5882352941176, Blast_Score=69, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6226542, Length=274, Percent_Identity=30.2919708029197, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 32535; Mature: 32404

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADHSPNADAYFVPSQSKWPFVGSIAMFVMMIGVASWLNDAAWGRWTFFAGVAMLLATLF
CCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MWFGDVIRESNAGHYNRQVDGSFRMGMVWFIFSEVMFFCAFFGALFYTRVLTLPWLGGEG
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DGVMTNELLWNGYSAAWPTNGPGTIGGQFQTIPAWGLPLINTLILLSSGVTLTIAHHALK
CCCCHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHC
GGRRGALLLWLGLTVLLGCVFLFLQAEEYIHAYTELNLTLGSGIYGSTFFMLTGFHGMHV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCHHHHH
LLGTIMLAVMWLRAAKGHFSRDNHFAFEAAAWYWHFVDVVWLALFLFVYVL
HHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
ADHSPNADAYFVPSQSKWPFVGSIAMFVMMIGVASWLNDAAWGRWTFFAGVAMLLATLF
CCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
MWFGDVIRESNAGHYNRQVDGSFRMGMVWFIFSEVMFFCAFFGALFYTRVLTLPWLGGEG
HHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DGVMTNELLWNGYSAAWPTNGPGTIGGQFQTIPAWGLPLINTLILLSSGVTLTIAHHALK
CCCCHHHHHHCCCCCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCCEEEEEHHHHC
GGRRGALLLWLGLTVLLGCVFLFLQAEEYIHAYTELNLTLGSGIYGSTFFMLTGFHGMHV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHCCHHHHH
LLGTIMLAVMWLRAAKGHFSRDNHFAFEAAAWYWHFVDVVWLALFLFVYVL
HHHHHHHHHHHHHHHCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3019767; 2832167; 7651515 [H]