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The map label for this gene is cox11 [H]

Identifier: 21244609

GI number: 21244609

Start: 4568299

End: 4568895

Strand: Reverse

Name: cox11 [H]

Synonym: XAC3885

Alternate gene names: 21244609

Gene position: 4568895-4568299 (Counterclockwise)

Preceding gene: 21244610

Following gene: 21244608

Centisome position: 88.28

GC content: 65.66

Gene sequence:

>597_bases
GTGAGTGCACGCGCGCCCGCACATGCACCAACCGCCGGCTTGTTCAAGCTGCTGGGCGTGGTGCTGGGCGTGTTTGTGCT
GACGTTTTCCCTGGTGCCGCTCTACCGCATCGCCTGCGAGAAAGTGTTTGGCATCCGCATGGAGCGTGCGCCTGGCAGCA
CGCGCGCAAACGCGGGCGCGCCACCTGCCGCCGGCAAGCGCACGGTGCGCGTGGAGTTCGATGGCGGGGTCAATTCCAAA
CTGCCGTGGACCTTCCATCCCGAACAGATGACGATGGATGTGGTGCCGGGCGAGCTCAACGAGGCGCTGTATTTCGCGCG
CAACGATGGCGCGCGTGCGGTGGTGGGCAGTGCGGTGCCCTCGGTTGCCCCTGCACGTGCGTCGGGCTACTTCAACAAAA
CCGAGTGCTTCTGCTTTACCGCGCAGACCTTGCAAGCCGGCGAAACGCGCGACATGCCGCTGCGTTTCATCGTCGACCCC
GCACTGCCGCCGGAAGTCACCACGATTACCTTGTCCTATACGTTCTATCGCAACGACGCGCTGACCTCGGAACTGCAGGG
CGGCGGCACGTCTGCCGCGCCGCGCGCCGCACCCTGA

Upstream 100 bases:

>100_bases
AGGCGCAGCAGCGCCGTGCGGTACGCCGTACCGCAATCACGGTCGGCATCATCGCGTTGCTGATCTATGCAGGCTTCATC
GCCTCGGGAGTCATCGGGCG

Downstream 100 bases:

>100_bases
TTCTTCATCCACACGCACCACGACACGGAAGCAACGCCATGGCCGATCACAGTCCCAACGCCGACGCGTATTTCGTCCCG
AGCCAGAGCAAATGGCCCTT

Product: cytochrome C oxidase assembly protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MSARAPAHAPTAGLFKLLGVVLGVFVLTFSLVPLYRIACEKVFGIRMERAPGSTRANAGAPPAAGKRTVRVEFDGGVNSK
LPWTFHPEQMTMDVVPGELNEALYFARNDGARAVVGSAVPSVAPARASGYFNKTECFCFTAQTLQAGETRDMPLRFIVDP
ALPPEVTTITLSYTFYRNDALTSELQGGGTSAAPRAAP

Sequences:

>Translated_198_residues
MSARAPAHAPTAGLFKLLGVVLGVFVLTFSLVPLYRIACEKVFGIRMERAPGSTRANAGAPPAAGKRTVRVEFDGGVNSK
LPWTFHPEQMTMDVVPGELNEALYFARNDGARAVVGSAVPSVAPARASGYFNKTECFCFTAQTLQAGETRDMPLRFIVDP
ALPPEVTTITLSYTFYRNDALTSELQGGGTSAAPRAAP
>Mature_197_residues
SARAPAHAPTAGLFKLLGVVLGVFVLTFSLVPLYRIACEKVFGIRMERAPGSTRANAGAPPAAGKRTVRVEFDGGVNSKL
PWTFHPEQMTMDVVPGELNEALYFARNDGARAVVGSAVPSVAPARASGYFNKTECFCFTAQTLQAGETRDMPLRFIVDPA
LPPEVTTITLSYTFYRNDALTSELQGGGTSAAPRAAP

Specific function: Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I [H]

COG id: COG3175

COG function: function code O; Cytochrome oxidase assembly factor

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX11/CtaG family [H]

Homologues:

Organism=Homo sapiens, GI4758034, Length=162, Percent_Identity=34.5679012345679, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI242247057, Length=124, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI242247061, Length=116, Percent_Identity=30.1724137931034, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71990692, Length=170, Percent_Identity=34.7058823529412, Blast_Score=104, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6325125, Length=160, Percent_Identity=37.5, Blast_Score=110, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24581944, Length=182, Percent_Identity=32.4175824175824, Blast_Score=105, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007533 [H]

Pfam domain/function: PF04442 CtaG_Cox11 [H]

EC number: NA

Molecular weight: Translated: 21080; Mature: 20949

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARAPAHAPTAGLFKLLGVVLGVFVLTFSLVPLYRIACEKVFGIRMERAPGSTRANAGA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCC
PPAAGKRTVRVEFDGGVNSKLPWTFHPEQMTMDVVPGELNEALYFARNDGARAVVGSAVP
CCCCCCEEEEEEECCCCCCCCCEEECCCCEEEECCCCCCCCEEEEEECCCCEEEECCCCC
SVAPARASGYFNKTECFCFTAQTLQAGETRDMPLRFIVDPALPPEVTTITLSYTFYRNDA
CCCCCHHCCCCCCCEEEEEEHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEEECCC
LTSELQGGGTSAAPRAAP
HHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SARAPAHAPTAGLFKLLGVVLGVFVLTFSLVPLYRIACEKVFGIRMERAPGSTRANAGA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCC
PPAAGKRTVRVEFDGGVNSKLPWTFHPEQMTMDVVPGELNEALYFARNDGARAVVGSAVP
CCCCCCEEEEEEECCCCCCCCCEEECCCCEEEECCCCCCCCEEEEEECCCCEEEECCCCC
SVAPARASGYFNKTECFCFTAQTLQAGETRDMPLRFIVDPALPPEVTTITLSYTFYRNDA
CCCCCHHCCCCCCCEEEEEEHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEEEEEEECCC
LTSELQGGGTSAAPRAAP
HHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA