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The map label for this gene is ugd [H]

Identifier: 21244306

GI number: 21244306

Start: 4247266

End: 4248432

Strand: Reverse

Name: ugd [H]

Synonym: XAC3581

Alternate gene names: 21244306

Gene position: 4248432-4247266 (Counterclockwise)

Preceding gene: 21244307

Following gene: 21244303

Centisome position: 82.09

GC content: 61.61

Gene sequence:

>1167_bases
ATGAAGATCGCTGTCGCGGGTACCGGCTATGTCGGTCTGTCCAATGGCGTGTTGCTCGCCAGGCACCATGAAGTGGTGGC
GCTGGACATCGTCGAGTCCAAGGTCAAGTTGCTCAACGAAGGCCGCTCGCCGATCGTCGACAAGGAACTCGAGGCCGCGC
TGGCCCAGGGTGGCCTGAACTTCAAGGCCACCCTGGACGCCAACGAGGCGTTTGCCGGCGCGGAGTTCGTGATCATCGCC
ACACCCACTGACTACGATCCGGACACCAACTATTTCAACACCGGGTCGATCGAGGTCGTGATCGCCAAGGTGCTGGAGAT
CAATCCGCAGGCGACCATGGTGATCAAATCCACCATTCCGGTCGGCTACGTCGCCAAGGTGCGCGCGCAGTTCGGGACCG
ACAACATCATCTTCTCGCCGGAATTCCTGCGCGAAGGCCGGGCGTTGTACGACAACCTGTACCCGTCCCGGATCATCGTC
GGCGAACGTTCGGCGCGCGCGGAGACCTTCGCGCGGCTGTTGCAGCAAGGCGCGCTCAAGCCCGACGTGCCGGTGTTGTT
CACCGAGCCGACCGAGGCCGAGGCGATCAAGCTGTTCGCCAATACCTACCTGGCGATGCGCGTGTCCTACTTCAACGAAC
TGGACACCTACGCGCTCACCCATGGGTTGGACAGCCGCCAGATCATCGAGGGCATTTGCCTGGATCCGCGTATCGGCAGC
CACTACAACAACCCGTCCTTCGGCTATGGCGGTTACTGCCTGCCTAAGGACACCAAGCAGCTGTTGGCCAACTACCAGAG
CGTGCCGCAGACCATCATCCGGGCGATCGTCGATTCCAACACGACCCGCAAGGACTTCATCGCCGCCGACGTGCTGCGAC
GCAATCCCAAGGTGGTCGGCATCTATCGGCTGATCATGAAGGCCGGGTCCGACAATTTCCGTTCGTCCAGCATCCAGGGG
GTGATGAAGCGCCTCAAGGCCAAGGGCGTGGACGTCATCGTGTACGAGCCGACCTTGAAAGATCCTGAGTTCTTCCGCTC
GCGCGTGGTCAACGACCTGCAGGCCTTCAAGCGCGAGGCCGACGTCATCATCAGCAACCGCATGGCCGAGGCGCTGCAGG
ACGTGCAGGACAAGGTGTATACGCGCGACCTGTTCGGCGACAACTGA

Upstream 100 bases:

>100_bases
GCGCGCCAGCCCCATTGCGGGCTCGGCCGCACCGTCATCACGCCATGGCCTGCATGCAGCGCGCTACATCCTCCCCCATC
CAATGTCGCAAGGAATTCCA

Downstream 100 bases:

>100_bases
GCCAGACCGGCGCTCAGTCCTGGCGGGTGGTGCCACCCGCCAGGTCACCCAGCTCACGGCGCTGCGGCGCTATTTGCCGC
CTCACGCAGCTACAGCGGTG

Product: UDP-glucose dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIAVAGTGYVGLSNGVLLARHHEVVALDIVESKVKLLNEGRSPIVDKELEAALAQGGLNFKATLDANEAFAGAEFVIIA
TPTDYDPDTNYFNTGSIEVVIAKVLEINPQATMVIKSTIPVGYVAKVRAQFGTDNIIFSPEFLREGRALYDNLYPSRIIV
GERSARAETFARLLQQGALKPDVPVLFTEPTEAEAIKLFANTYLAMRVSYFNELDTYALTHGLDSRQIIEGICLDPRIGS
HYNNPSFGYGGYCLPKDTKQLLANYQSVPQTIIRAIVDSNTTRKDFIAADVLRRNPKVVGIYRLIMKAGSDNFRSSSIQG
VMKRLKAKGVDVIVYEPTLKDPEFFRSRVVNDLQAFKREADVIISNRMAEALQDVQDKVYTRDLFGDN

Sequences:

>Translated_388_residues
MKIAVAGTGYVGLSNGVLLARHHEVVALDIVESKVKLLNEGRSPIVDKELEAALAQGGLNFKATLDANEAFAGAEFVIIA
TPTDYDPDTNYFNTGSIEVVIAKVLEINPQATMVIKSTIPVGYVAKVRAQFGTDNIIFSPEFLREGRALYDNLYPSRIIV
GERSARAETFARLLQQGALKPDVPVLFTEPTEAEAIKLFANTYLAMRVSYFNELDTYALTHGLDSRQIIEGICLDPRIGS
HYNNPSFGYGGYCLPKDTKQLLANYQSVPQTIIRAIVDSNTTRKDFIAADVLRRNPKVVGIYRLIMKAGSDNFRSSSIQG
VMKRLKAKGVDVIVYEPTLKDPEFFRSRVVNDLQAFKREADVIISNRMAEALQDVQDKVYTRDLFGDN
>Mature_388_residues
MKIAVAGTGYVGLSNGVLLARHHEVVALDIVESKVKLLNEGRSPIVDKELEAALAQGGLNFKATLDANEAFAGAEFVIIA
TPTDYDPDTNYFNTGSIEVVIAKVLEINPQATMVIKSTIPVGYVAKVRAQFGTDNIIFSPEFLREGRALYDNLYPSRIIV
GERSARAETFARLLQQGALKPDVPVLFTEPTEAEAIKLFANTYLAMRVSYFNELDTYALTHGLDSRQIIEGICLDPRIGS
HYNNPSFGYGGYCLPKDTKQLLANYQSVPQTIIRAIVDSNTTRKDFIAADVLRRNPKVVGIYRLIMKAGSDNFRSSSIQG
VMKRLKAKGVDVIVYEPTLKDPEFFRSRVVNDLQAFKREADVIISNRMAEALQDVQDKVYTRDLFGDN

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=386, Percent_Identity=25.1295336787565, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI296040438, Length=259, Percent_Identity=26.2548262548263, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI296040443, Length=233, Percent_Identity=26.1802575107296, Blast_Score=78, Evalue=2e-14,
Organism=Escherichia coli, GI1788340, Length=388, Percent_Identity=71.3917525773196, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI48994968, Length=379, Percent_Identity=25.065963060686, Blast_Score=84, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17560350, Length=398, Percent_Identity=27.8894472361809, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI17136908, Length=387, Percent_Identity=24.2894056847545, Blast_Score=95, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 42998; Mature: 42998

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVAGTGYVGLSNGVLLARHHEVVALDIVESKVKLLNEGRSPIVDKELEAALAQGGLN
CEEEEECCCCEECCCCEEEEECCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
FKATLDANEAFAGAEFVIIATPTDYDPDTNYFNTGSIEVVIAKVLEINPQATMVIKSTIP
EEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHEEEEHHHHCCCCEEEEEEECCC
VGYVAKVRAQFGTDNIIFSPEFLREGRALYDNLYPSRIIVGERSARAETFARLLQQGALK
CCHHHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCC
PDVPVLFTEPTEAEAIKLFANTYLAMRVSYFNELDTYALTHGLDSRQIIEGICLDPRIGS
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCC
HYNNPSFGYGGYCLPKDTKQLLANYQSVPQTIIRAIVDSNTTRKDFIAADVLRRNPKVVG
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEH
IYRLIMKAGSDNFRSSSIQGVMKRLKAKGVDVIVYEPTLKDPEFFRSRVVNDLQAFKREA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
DVIISNRMAEALQDVQDKVYTRDLFGDN
HHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKIAVAGTGYVGLSNGVLLARHHEVVALDIVESKVKLLNEGRSPIVDKELEAALAQGGLN
CEEEEECCCCEECCCCEEEEECCCEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCC
FKATLDANEAFAGAEFVIIATPTDYDPDTNYFNTGSIEVVIAKVLEINPQATMVIKSTIP
EEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHEEEEHHHHCCCCEEEEEEECCC
VGYVAKVRAQFGTDNIIFSPEFLREGRALYDNLYPSRIIVGERSARAETFARLLQQGALK
CCHHHHHHHHCCCCCEEECHHHHHCCHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCC
PDVPVLFTEPTEAEAIKLFANTYLAMRVSYFNELDTYALTHGLDSRQIIEGICLDPRIGS
CCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCC
HYNNPSFGYGGYCLPKDTKQLLANYQSVPQTIIRAIVDSNTTRKDFIAADVLRRNPKVVG
CCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCEEH
IYRLIMKAGSDNFRSSSIQGVMKRLKAKGVDVIVYEPTLKDPEFFRSRVVNDLQAFKREA
HHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHH
DVIISNRMAEALQDVQDKVYTRDLFGDN
HHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9383197 [H]