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The map label for this gene is ipsI [H]

Identifier: 21244303

GI number: 21244303

Start: 4243325

End: 4244056

Strand: Reverse

Name: ipsI [H]

Synonym: XAC3578

Alternate gene names: 21244303

Gene position: 4244056-4243325 (Counterclockwise)

Preceding gene: 21244306

Following gene: 21244302

Centisome position: 82.0

GC content: 63.11

Gene sequence:

>732_bases
ATGCGCAGCGAAGGACGTGGTGCGGCAAGCGGCAAACGCTATGCCGATGCCAAGGCAGCACTGGGCGGGGTACTGGCCAA
TGGTCAGACCCTGGCGGTGGGCGGCTTTGGGTTGTGTGGAATCCCGGAGGCATTGATTGCAGCCGTGCGCGACAGTGGGG
TCGGCGGGTTGACCGTGATCTCCAACAACGCTGGCGTCGACGGATTCGGGCTTGGTCAATTATTGGCCACCCGGCAGATC
CGCAAGATGATTTCGTCCTACGTGGGCGAAAACAAGGAATTCGAACGCCAATACCTGGCGGGCGAACTCGAGCTGGAGTT
CAATCCGCAAGGCACCCTGGCCGAGCGTTTGCGCGCCGGTGGCGCGGGCATTCCTGCGTTTTACACCGCCACCGGCTACG
GCACGATCGTGGCCGAGGGCAAGGAAACGCGCGAATTCGACGGCAAGCATTACGTGCTGGAAACCGCGTTGCAGGCCGAC
GTGGCGCTGGTCAAGGCATGGCGCGCCGATACCGCTGGCAACCTGGTATTCCGCAAGACCGCGCGCAATTTCAATCCCGC
CTGCGCCATGGCCGGACGCGTGTGCATCGCCGAGGTCGAGGACATCGTGGAGCTGGGCGTCATCGATCCGGATCAGGTGC
ATCTGCCCGGCATTTACGTGGACCGCCTGGTGCTCAACGCCACGCCGGAAAAACGCATCGAACAGCGCACCGTGCGCGAA
GGACAGCAGTGA

Upstream 100 bases:

>100_bases
GCGGCTGCGCTGTGTCTTGGGTGTGGCGGAATTGCGACCGGGGACAGGGAACAGTCAGCGGATAGAATGGGCGCTTCACA
TCAGCGAGGTGAGGGCGGTG

Downstream 100 bases:

>100_bases
TGGCCTGGACCAGAGACCAGATGGCCGCACGCGCGGCACGCGAACTGACCGATGGCGCCTACGTCAACCTGGGCATCGGC
TTGCCGACGCTGGTCGCCAA

Product: IpsJ protein

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 243; Mature: 243

Protein sequence:

>243_residues
MRSEGRGAASGKRYADAKAALGGVLANGQTLAVGGFGLCGIPEALIAAVRDSGVGGLTVISNNAGVDGFGLGQLLATRQI
RKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAGGAGIPAFYTATGYGTIVAEGKETREFDGKHYVLETALQAD
VALVKAWRADTAGNLVFRKTARNFNPACAMAGRVCIAEVEDIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
GQQ

Sequences:

>Translated_243_residues
MRSEGRGAASGKRYADAKAALGGVLANGQTLAVGGFGLCGIPEALIAAVRDSGVGGLTVISNNAGVDGFGLGQLLATRQI
RKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAGGAGIPAFYTATGYGTIVAEGKETREFDGKHYVLETALQAD
VALVKAWRADTAGNLVFRKTARNFNPACAMAGRVCIAEVEDIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
GQQ
>Mature_243_residues
MRSEGRGAASGKRYADAKAALGGVLANGQTLAVGGFGLCGIPEALIAAVRDSGVGGLTVISNNAGVDGFGLGQLLATRQI
RKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAGGAGIPAFYTATGYGTIVAEGKETREFDGKHYVLETALQAD
VALVKAWRADTAGNLVFRKTARNFNPACAMAGRVCIAEVEDIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
GQQ

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=55.4655870445344, Blast_Score=280, Evalue=6e-76,
Organism=Homo sapiens, GI11545841, Length=245, Percent_Identity=54.2857142857143, Blast_Score=247, Evalue=8e-66,
Organism=Escherichia coli, GI1788551, Length=204, Percent_Identity=42.6470588235294, Blast_Score=182, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17531517, Length=244, Percent_Identity=56.9672131147541, Blast_Score=267, Evalue=4e-72,
Organism=Drosophila melanogaster, GI21358325, Length=249, Percent_Identity=48.995983935743, Blast_Score=242, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24655794, Length=249, Percent_Identity=48.995983935743, Blast_Score=241, Evalue=2e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25826; Mature: 25826

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSEGRGAASGKRYADAKAALGGVLANGQTLAVGGFGLCGIPEALIAAVRDSGVGGLTVI
CCCCCCCCCCCCHHHHHHHHHHHHEECCCEEEECCCCCCCHHHHHHHHHHCCCCCCEEEE
SNNAGVDGFGLGQLLATRQIRKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAG
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCC
GAGIPAFYTATGYGTIVAEGKETREFDGKHYVLETALQADVALVKAWRADTAGNLVFRKT
CCCCCEEEEECCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
ARNFNPACAMAGRVCIAEVEDIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
CCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCEECCCEEEHHHEECCCCHHHHHHHHHHC
GQQ
CCC
>Mature Secondary Structure
MRSEGRGAASGKRYADAKAALGGVLANGQTLAVGGFGLCGIPEALIAAVRDSGVGGLTVI
CCCCCCCCCCCCHHHHHHHHHHHHEECCCEEEECCCCCCCHHHHHHHHHHCCCCCCEEEE
SNNAGVDGFGLGQLLATRQIRKMISSYVGENKEFERQYLAGELELEFNPQGTLAERLRAG
ECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHHHCC
GAGIPAFYTATGYGTIVAEGKETREFDGKHYVLETALQADVALVKAWRADTAGNLVFRKT
CCCCCEEEEECCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEC
ARNFNPACAMAGRVCIAEVEDIVELGVIDPDQVHLPGIYVDRLVLNATPEKRIEQRTVRE
CCCCCHHHHHHCCHHHHHHHHHHHHCCCCCCCEECCCEEEHHHEECCCCHHHHHHHHHHC
GQQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]