Click here to switch to the map view.

The map label for this gene is ppa

Identifier: 21244167

GI number: 21244167

Start: 4053487

End: 4054023

Strand: Direct

Name: ppa

Synonym: XAC3442

Alternate gene names: 21244167

Gene position: 4053487-4054023 (Clockwise)

Preceding gene: 21244165

Following gene: 21244168

Centisome position: 78.32

GC content: 62.01

Gene sequence:

>537_bases
ATGGGCCTTGAACTGGTCACCTCTGGCAAGAATCTGCCGGAAGAAATCAACGTCGTCATCGAGATCCCCAAGGATTCCGA
GCCGGTCAAGTACGAAGTCGACAAGGCCAGCGGGGCGATCTTCGTGGACCGCATTCTGTCGACCCCGATGCGTTACCCCT
GCAACTATGGCTACGTGCCCAACACCCTGTGCGGCGATGGCGACCCGGCCGACGTGCTGGTGGTGCTGCCGTTGCCATTG
GTGCCGGGCTCGGTGGTGCGCTGCCGTCCGGTGGGCGTGCTGCGCATGAGCGACGAAGCCGGCAGCGACGAAAAGATCCT
GGCCGTGCCGATCGAGAAGATCTTCTCCGGTTACGCGCACATCGAAGACATCAACCAGGTGTCCAGCCACTGGATGGAGC
GTATCGGCCACTTCTTCGAGCACTACAAGGACTTGGAGAAGGGCAAGTGGGTCAAGCTGGATGGCTGGGGCGGCGCGGCC
GAGGCCAAGCGCATCCTGACCGAGTCGGTGGAACGCTACAATTCCGACGCACCCTGA

Upstream 100 bases:

>100_bases
TGCAGCGGTCAGGACATTGCCCATTCAGTGTCGCTGCAGCGCAACAGCCGAACGCGTAGAATCGCGCTCCACATACTGCT
GACGCCTCGGAGCTACCCGC

Downstream 100 bases:

>100_bases
TCCATCGATCGTGATGCTGCCCTGCGTGTAGGGCGGGCGACCGGGATCACGCTTCTGGCGTGATCCCGGTGACCGCAGTC
GGCAGATTGGGTACATTGCC

Product: inorganic pyrophosphatase

Products: NA

Alternate protein names: Pyrophosphate phospho-hydrolase; PPase

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MGLELVTSGKNLPEEINVVIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVPNTLCGDGDPADVLVVLPLPL
VPGSVVRCRPVGVLRMSDEAGSDEKILAVPIEKIFSGYAHIEDINQVSSHWMERIGHFFEHYKDLEKGKWVKLDGWGGAA
EAKRILTESVERYNSDAP

Sequences:

>Translated_178_residues
MGLELVTSGKNLPEEINVVIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVPNTLCGDGDPADVLVVLPLPL
VPGSVVRCRPVGVLRMSDEAGSDEKILAVPIEKIFSGYAHIEDINQVSSHWMERIGHFFEHYKDLEKGKWVKLDGWGGAA
EAKRILTESVERYNSDAP
>Mature_177_residues
GLELVTSGKNLPEEINVVIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVPNTLCGDGDPADVLVVLPLPLV
PGSVVRCRPVGVLRMSDEAGSDEKILAVPIEKIFSGYAHIEDINQVSSHWMERIGHFFEHYKDLEKGKWVKLDGWGGAAE
AKRILTESVERYNSDAP

Specific function: Unknown

COG id: COG0221

COG function: function code C; Inorganic pyrophosphatase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PPase family

Homologues:

Organism=Escherichia coli, GI1790673, Length=172, Percent_Identity=60.4651162790698, Blast_Score=219, Evalue=7e-59,

Paralogues:

None

Copy number: 5480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): IPYR_XANAC (Q8PH18)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643749.1
- ProteinModelPortal:   Q8PH18
- SMR:   Q8PH18
- GeneID:   1157513
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC3442
- HOGENOM:   HBG529150
- OMA:   IMVIMRE
- ProtClustDB:   PRK01250
- BioCyc:   XAXO190486:XAC3442-MONOMER
- BRENDA:   3.6.1.1
- GO:   GO:0005737
- HAMAP:   MF_00209
- InterPro:   IPR008162
- Gene3D:   G3DSA:3.90.80.10
- PANTHER:   PTHR10286

Pfam domain/function: PF00719 Pyrophosphatase; SSF50324 Pyrophosphatase

EC number: =3.6.1.1

Molecular weight: Translated: 19714; Mature: 19583

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS00387 PPASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLELVTSGKNLPEEINVVIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVP
CCCEEEECCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCC
NTLCGDGDPADVLVVLPLPLVPGSVVRCRPVGVLRMSDEAGSDEKILAVPIEKIFSGYAH
CCCCCCCCCCCEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCEEEEEHHHHHCCHHH
IEDINQVSSHWMERIGHFFEHYKDLEKGKWVKLDGWGGAAEAKRILTESVERYNSDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
GLELVTSGKNLPEEINVVIEIPKDSEPVKYEVDKASGAIFVDRILSTPMRYPCNYGYVP
CCEEEECCCCCCCEEEEEEECCCCCCCCEEEECCCCCCCHHHHHHCCCCCCCCCCCCCC
NTLCGDGDPADVLVVLPLPLVPGSVVRCRPVGVLRMSDEAGSDEKILAVPIEKIFSGYAH
CCCCCCCCCCCEEEEEECCCCCCCEEEECCCEEEEECCCCCCCCCEEEEEHHHHHCCHHH
IEDINQVSSHWMERIGHFFEHYKDLEKGKWVKLDGWGGAAEAKRILTESVERYNSDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217