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The map label for this gene is yggW [H]

Identifier: 21244125

GI number: 21244125

Start: 4006095

End: 4007252

Strand: Direct

Name: yggW [H]

Synonym: XAC3400

Alternate gene names: 21244125

Gene position: 4006095-4007252 (Clockwise)

Preceding gene: 21244124

Following gene: 77748713

Centisome position: 77.4

GC content: 65.11

Gene sequence:

>1158_bases
ATGCCCCAGCTGATTCCACCGCCGCTGTCGCTCTACGTGCACCTGCCCTGGTGCGTGCGCAAATGCCCGTACTGCGATTT
CAACTCGCATGCGGCAAAGGGCGCATTGCCGTTCGAGGCGTACGTGGACGCGCTGATCCGCGACCTGGATGCGGACCTGC
CGTTGGTCTGGGGCCGCGTGGTGCATTCGGTGTTCTTCGGCGGCGGCACGCCCAGCCTGTTTCCGCCGCAGGCGATCGAC
CGCTTTCTGCAGGCAGCAGCGGCGCGGCTGCGTTTTGCCCCGAATCTTGAGATCACCCTGGAAACCAATCCCGGTACCGC
CGAGCATGGCCGTTTCGAGCATTACCGCGCTGCTGGCGTGAATCGCCTGAGCTTCGGTGTGCAGACCTTCGACGATGTGG
CGCTGCAGCGACTCGGCCGTATTCACGACAGCGCCGAAGCCGAGCGCGCGATCAAACTGGCGCAGGACGCCGGCTACGAT
AATTTCAACATCGACCTGATGTACGCACTGCCCGAGCAGACGCTGATGCAGGCCGAGCACGATCTGGAGCGCGCCTTCGC
GCTGCAGCCGGCGCACCTGTCGCATTACCAGCTCACGCTGGAGCCGAACACGGTGTTCTTCGCGCGGCCGCCCAAGGGCA
TTCCCGACGACGATGCCGCCTGGGATATCCAGGAACACTGCCAAGGCCTGCTGGCCGACGCCGGCTACGCCCAGTACGAA
GTCAGCGCATATGCCAAGCCGGGGCGGCAGTGCGCGCACAACCTCAACTACTGGCGGTTCGGCGATTACCTGGGCATCGG
CGCGGGCGCGCACGGCAAGATCAGCTCCGGTGCCGAAGCGCACGTGCTGCGGCGCTGGAAGCACAAGCATCCGCAGAGCT
ATCTGGCCAGCGCCGGCACTGCTGCATCCATCGGCGGCGATGAAATCGTACCGGGCGAACGGCTGCCGTTCGAATACATG
CTCAATCTGCTGCGCCTGCATGAGGGCTTCCGGCTAAGCGATTTCGAGGCGTCGACTGGCCTTGCGGCCTGCGCCATCGA
GGCGCCGCTGGCGCGCGCAGTGGCAAAGGGCTGGATGAGGCAGCAAGACGGGCGCGTGGTGCCGACCGAGCTGGGACGGC
GTTTCACCAATGATGTGGTCGAGTTGTTCCTGGTCTAG

Upstream 100 bases:

>100_bases
GGACACCGCGTTGAAGAACCGCCTGAGCCATCGTGCGGTCGCCCTGGCCACGCTGCAGCACAAGCTGCATGCGATGTCGC
TGTAAGGCACGCCTCGCGCA

Downstream 100 bases:

>100_bases
GCGCAGCGAGCGACTGCGCTCACTGCCAGGTCGGCGTGGCCGGGCGCTTGGCATCGGCATGTACCGCCTGCGCACAGTGC
GTCCAGTGCGCCATCCACGC

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 385; Mature: 384

Protein sequence:

>385_residues
MPQLIPPPLSLYVHLPWCVRKCPYCDFNSHAAKGALPFEAYVDALIRDLDADLPLVWGRVVHSVFFGGGTPSLFPPQAID
RFLQAAAARLRFAPNLEITLETNPGTAEHGRFEHYRAAGVNRLSFGVQTFDDVALQRLGRIHDSAEAERAIKLAQDAGYD
NFNIDLMYALPEQTLMQAEHDLERAFALQPAHLSHYQLTLEPNTVFFARPPKGIPDDDAAWDIQEHCQGLLADAGYAQYE
VSAYAKPGRQCAHNLNYWRFGDYLGIGAGAHGKISSGAEAHVLRRWKHKHPQSYLASAGTAASIGGDEIVPGERLPFEYM
LNLLRLHEGFRLSDFEASTGLAACAIEAPLARAVAKGWMRQQDGRVVPTELGRRFTNDVVELFLV

Sequences:

>Translated_385_residues
MPQLIPPPLSLYVHLPWCVRKCPYCDFNSHAAKGALPFEAYVDALIRDLDADLPLVWGRVVHSVFFGGGTPSLFPPQAID
RFLQAAAARLRFAPNLEITLETNPGTAEHGRFEHYRAAGVNRLSFGVQTFDDVALQRLGRIHDSAEAERAIKLAQDAGYD
NFNIDLMYALPEQTLMQAEHDLERAFALQPAHLSHYQLTLEPNTVFFARPPKGIPDDDAAWDIQEHCQGLLADAGYAQYE
VSAYAKPGRQCAHNLNYWRFGDYLGIGAGAHGKISSGAEAHVLRRWKHKHPQSYLASAGTAASIGGDEIVPGERLPFEYM
LNLLRLHEGFRLSDFEASTGLAACAIEAPLARAVAKGWMRQQDGRVVPTELGRRFTNDVVELFLV
>Mature_384_residues
PQLIPPPLSLYVHLPWCVRKCPYCDFNSHAAKGALPFEAYVDALIRDLDADLPLVWGRVVHSVFFGGGTPSLFPPQAIDR
FLQAAAARLRFAPNLEITLETNPGTAEHGRFEHYRAAGVNRLSFGVQTFDDVALQRLGRIHDSAEAERAIKLAQDAGYDN
FNIDLMYALPEQTLMQAEHDLERAFALQPAHLSHYQLTLEPNTVFFARPPKGIPDDDAAWDIQEHCQGLLADAGYAQYEV
SAYAKPGRQCAHNLNYWRFGDYLGIGAGAHGKISSGAEAHVLRRWKHKHPQSYLASAGTAASIGGDEIVPGERLPFEYML
NLLRLHEGFRLSDFEASTGLAACAIEAPLARAVAKGWMRQQDGRVVPTELGRRFTNDVVELFLV

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=277, Percent_Identity=39.3501805054152, Blast_Score=190, Evalue=2e-48,
Organism=Escherichia coli, GI1789325, Length=378, Percent_Identity=51.0582010582011, Blast_Score=374, Evalue=1e-105,
Organism=Escherichia coli, GI87082341, Length=247, Percent_Identity=31.1740890688259, Blast_Score=126, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 42685; Mature: 42554

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQLIPPPLSLYVHLPWCVRKCPYCDFNSHAAKGALPFEAYVDALIRDLDADLPLVWGRV
CCCCCCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
VHSVFFGGGTPSLFPPQAIDRFLQAAAARLRFAPNLEITLETNPGTAEHGRFEHYRAAGV
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHCC
NRLSFGVQTFDDVALQRLGRIHDSAEAERAIKLAQDAGYDNFNIDLMYALPEQTLMQAEH
CHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHH
DLERAFALQPAHLSHYQLTLEPNTVFFARPPKGIPDDDAAWDIQEHCQGLLADAGYAQYE
HHHHHHHCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEE
VSAYAKPGRQCAHNLNYWRFGDYLGIGAGAHGKISSGAEAHVLRRWKHKHPQSYLASAGT
HHHHCCCHHHHHHCCCCEEECCEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCC
AASIGGDEIVPGERLPFEYMLNLLRLHEGFRLSDFEASTGLAACAIEAPLARAVAKGWMR
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QQDGRVVPTELGRRFTNDVVELFLV
HCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PQLIPPPLSLYVHLPWCVRKCPYCDFNSHAAKGALPFEAYVDALIRDLDADLPLVWGRV
CCCCCCCCEEEEECCHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHH
VHSVFFGGGTPSLFPPQAIDRFLQAAAARLRFAPNLEITLETNPGTAEHGRFEHYRAAGV
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCHHHHHHCC
NRLSFGVQTFDDVALQRLGRIHDSAEAERAIKLAQDAGYDNFNIDLMYALPEQTLMQAEH
CHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHH
DLERAFALQPAHLSHYQLTLEPNTVFFARPPKGIPDDDAAWDIQEHCQGLLADAGYAQYE
HHHHHHHCCCCCCCEEEEEECCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEE
VSAYAKPGRQCAHNLNYWRFGDYLGIGAGAHGKISSGAEAHVLRRWKHKHPQSYLASAGT
HHHHCCCHHHHHHCCCCEEECCEEEECCCCCCCCCCCHHHHHHHHHHHCCCHHHHHHCCC
AASIGGDEIVPGERLPFEYMLNLLRLHEGFRLSDFEASTGLAACAIEAPLARAVAKGWMR
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
QQDGRVVPTELGRRFTNDVVELFLV
HCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]