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The map label for this gene is yggV [C]

Identifier: 21244124

GI number: 21244124

Start: 4005456

End: 4006079

Strand: Direct

Name: yggV [C]

Synonym: XAC3399

Alternate gene names: 21244124

Gene position: 4005456-4006079 (Clockwise)

Preceding gene: 21244123

Following gene: 21244125

Centisome position: 77.39

GC content: 65.38

Gene sequence:

>624_bases
GTGGGATCTACTGGAGCCAAAGCAATGAAACAACTGGTCCTGGCCAGCGGCAACGCCGGCAAGCTGGAAGAACTGCGCGC
CATGCTGGCCGGCCTGCCGCTGCGCGTCGTCGCGCAAGGCGAGCTCGGCGTGGAAGATGTTCCGGAAACCGGCCTGACCT
TCGTCGAGAACGCCCTGATCAAGGCGCGCCATGCCAGCGCAGTGACCGGCTTGCCGGCGCTGGCCGATGATTCGGGGCTG
ATCGTGGATGCATTGGATGGCGCACCCGGTCTGTACAGCGCGCGCTATGCCGGCAGCCCGACCAACGCGTTGGCCAACAA
CGCCAAGTTGCTCGACGCGATGCGCGAGGTTCCGAGCGATCGCCGCAGCGCGCGGTTTTATGCGGTGATCGTGTTGCTGC
GGCATCCGGAAGATCCGCAGCCGCTGATCGCCGAAGGCAGCTGGGAAGGGGTGATCACCACGCAACCGCGCGGCGATGGC
GGCTTCGGCTACAACCCGGTGTTTCTGGATCCGGTGTATGGCCTGACCGCGGCGGAGATGGACACCGCGTTGAAGAACCG
CCTGAGCCATCGTGCGGTCGCCCTGGCCACGCTGCAGCACAAGCTGCATGCGATGTCGCTGTAA

Upstream 100 bases:

>100_bases
ACCACGCGGCCATGCAGGCGTTCGGCGTGGAATTTCTGGAAACCCCGCGCGAAGAGCCGTACGGCACGGTCGTGGTCTTC
CGCGATCTGTACGGCACCAA

Downstream 100 bases:

>100_bases
GGCACGCCTCGCGCAATGCCCCAGCTGATTCCACCGCCGCTGTCGCTCTACGTGCACCTGCCCTGGTGCGTGCGCAAATG
CCCGTACTGCGATTTCAACT

Product: deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MGSTGAKAMKQLVLASGNAGKLEELRAMLAGLPLRVVAQGELGVEDVPETGLTFVENALIKARHASAVTGLPALADDSGL
IVDALDGAPGLYSARYAGSPTNALANNAKLLDAMREVPSDRRSARFYAVIVLLRHPEDPQPLIAEGSWEGVITTQPRGDG
GFGYNPVFLDPVYGLTAAEMDTALKNRLSHRAVALATLQHKLHAMSL

Sequences:

>Translated_207_residues
MGSTGAKAMKQLVLASGNAGKLEELRAMLAGLPLRVVAQGELGVEDVPETGLTFVENALIKARHASAVTGLPALADDSGL
IVDALDGAPGLYSARYAGSPTNALANNAKLLDAMREVPSDRRSARFYAVIVLLRHPEDPQPLIAEGSWEGVITTQPRGDG
GFGYNPVFLDPVYGLTAAEMDTALKNRLSHRAVALATLQHKLHAMSL
>Mature_206_residues
GSTGAKAMKQLVLASGNAGKLEELRAMLAGLPLRVVAQGELGVEDVPETGLTFVENALIKARHASAVTGLPALADDSGLI
VDALDGAPGLYSARYAGSPTNALANNAKLLDAMREVPSDRRSARFYAVIVLLRHPEDPQPLIAEGSWEGVITTQPRGDGG
FGYNPVFLDPVYGLTAAEMDTALKNRLSHRAVALATLQHKLHAMSL

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Escherichia coli, GI1789324, Length=190, Percent_Identity=56.3157894736842, Blast_Score=224, Evalue=5e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_XANAC (Q8PH61)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_643706.1
- ProteinModelPortal:   Q8PH61
- GeneID:   1157470
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC3399
- NMPDR:   fig|190486.1.peg.3350
- HOGENOM:   HBG697237
- OMA:   TGVTFAE
- ProtClustDB:   PRK00120
- BioCyc:   XAXO190486:XAC3399-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067
- TIGRFAMs:   TIGR00042

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 21792; Mature: 21661

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGSTGAKAMKQLVLASGNAGKLEELRAMLAGLPLRVVAQGELGVEDVPETGLTFVENALI
CCCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
KARHASAVTGLPALADDSGLIVDALDGAPGLYSARYAGSPTNALANNAKLLDAMREVPSD
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
RRSARFYAVIVLLRHPEDPQPLIAEGSWEGVITTQPRGDGGFGYNPVFLDPVYGLTAAEM
HHCCEEEEEEEEEECCCCCCCEEECCCCCCEEEECCCCCCCCCCCCEEECCCCCCHHHHH
DTALKNRLSHRAVALATLQHKLHAMSL
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GSTGAKAMKQLVLASGNAGKLEELRAMLAGLPLRVVAQGELGVEDVPETGLTFVENALI
CCHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCHHHHHHHHHH
KARHASAVTGLPALADDSGLIVDALDGAPGLYSARYAGSPTNALANNAKLLDAMREVPSD
HHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCC
RRSARFYAVIVLLRHPEDPQPLIAEGSWEGVITTQPRGDGGFGYNPVFLDPVYGLTAAEM
HHCCEEEEEEEEEECCCCCCCEEECCCCCCEEEECCCCCCCCCCCCEEECCCCCCHHHHH
DTALKNRLSHRAVALATLQHKLHAMSL
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217