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The map label for this gene is cysJ [H]

Identifier: 21244055

GI number: 21244055

Start: 3922907

End: 3924754

Strand: Direct

Name: cysJ [H]

Synonym: XAC3330

Alternate gene names: 21244055

Gene position: 3922907-3924754 (Clockwise)

Preceding gene: 21244050

Following gene: 21244056

Centisome position: 75.8

GC content: 69.16

Gene sequence:

>1848_bases
ATGACCGCCGCCAGTTCCGCGCTACCGCCCAGCCCCTTGCCCGACGAGCGCAAGGTGCTGCTGGACCGGTTGGTCGACGG
CCTGGACACCGCATCGCTGTGGTGGCTGTCCGGCTACGCTGCCGGGCTGGCGCAGGGCCATCCGCCGCGCTCGCTGGCGG
TGTTGCCGGGCGGACAGGCGCACCCACTCGCCCAGGAAGGCCAACGCCTGACCGTGGTGTACGGCAGCCAGACCGGCAAT
GCCCGTCGCGAGGCAGAGCACCTAGCCGCCGAGGCCGAAGCCGCGGGTCTGAGCGTGCGCCTGGTGCGCGCCGACGCCTA
CCCCACCCGCGAGCTGGCCAGTGAGCGGCTGTTGTATGTGGTGATCAGCACCCAGGGCGAAGGTGACCCGCCAGACGATG
CGATCGGCCTGGTGGAATTCCTGAGCAGCCGGCGCGCGCCTAAGGTGCCCGAGCTCAAGTACGCGGTCCTGGGCCTGGGC
GATTCCAGTTATGCCGATTTCTGCGGTATTGCCCGGCGCATCGACGAGCGCCTGGCCGAACTGGGCGGCAGCCGCGTGCA
GCCGCGCGGCGAAGCCGATCTGGACATCGACAGCGTTGCCCTGCCGTGGCGCGCACAGGCGCTCACGCATGCGCGCGAGC
AGCTCAAGGGCGGCCTGCACTCGGCCACGGTCACGCCGCTGCGCAGCAGCCCGGCCACGCCGGTGTGGTCGCACCAGCAG
CCGTTCGCCGCCGAGTTGTTGTCCAATCAGATCATCAGCGGACGCGACTTCAAGGGCCCGGGATTTCGCGTCTATGCGGC
GCCCGGCAAGCGCGTGCGGCATCTGGAATTTTCGCTGCAAGGCAGCGGCCTGAGCTATGAGCCGGGCGACGCGCTGGGCA
TCCGCCACCGCAATCCGCCCGCATTGGTCGATGCGGTGCTGCAGACCTTGCGGTTGGACGGCGATGCCGCGGTCACCATC
GGCGAGCAGACATTGGAATTGCATGCATGGCTCGCCACCCAGCGCGAACTGACCAAGCTGTCGCGGCCGTTCCTCACCGC
ACATGCCGAGCGCGCAGGCGCGCAAGAACTGCAAGCGCTGCTCGCCCCCACCCAGACTGCCGGCCTGGCGTCGCTGCTCG
CCGATCATCAAGTGATCGACGTGCTGCGCCGCTGGCCGGCGGATTGGGACCACGCCGGCCTGCTCGCCGCGCTGCGTCCC
CTCACCCCGCGGCTGTACTCCGTCGCCTCCAGCCGCAAGCGCGTGGGCGATGAAGTGCATCTGACCGTGGACGAGGTCAC
CTACCAGGCGCATGGGCATGCGCATCTGGGTGCGGCCAGCGGCTTTCTGGCCGCGCTTGGCGAAGGCGACACCGCGCCGG
TCTACATCGAACCGAACGAGCGCTTCCGGGTACCGGCCGATGCCGATCGCGACATCCTGATGATCGGCCCGGGCACCGGC
GTGGCGCCGTTCCGCGGCTTCGTGCAGGAGCGCGCGGAAACCGGCGCCAAGGGCCGTAACTGGCTGTTCTTCGGCGCCCA
GCATTTCAATACCGATTTCCTGTACCAGGCCGAATGGCAGCTGGCCCTGCGACGCGGCGAGTTGCACGCGCTGGATCTGG
CGTTCTCGCGCGACCAGGCCGAAAAGCTCTACGTGCAACATCGCCTGCGCGCGCGTGGCGCCGAGGTCTATGCCTGGCTG
CAGGGCGGCGCGCACGTGTATGTGTGCGGCGCCACCAGCATGGGCAAGGACGTGCATGCGGCCCTGCTCGACATCGTCGC
CACCCACGGCGCCCAGGATGCCGAGGCCGCCGCCGCGTATCTCACCCAACTGCAGGTGGAGGGACGCTATGCACGGGATG
TCTATTAG

Upstream 100 bases:

>100_bases
CGAAATAAGCGCCCGGCATAACGCGATAACGGCAATTCCTTTCTGGTGGGCGCAACGCTTCCCTAACATCGTCACTCTCA
TCACCCCCCCCCGGATCCGA

Downstream 100 bases:

>100_bases
TGCCGGGAATCGCGAGTGGGGAATCGGGAATGGGAAGAGCCCATGTCCGAGTTCTTCCGACCAACTGCGCCGCTTTTCAC
GATTCCCCATTCCCGATTCT

Product: NADPH-sulfite reductase flavoprotein subunit

Products: NA

Alternate protein names: SiR-FP [H]

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MTAASSALPPSPLPDERKVLLDRLVDGLDTASLWWLSGYAAGLAQGHPPRSLAVLPGGQAHPLAQEGQRLTVVYGSQTGN
ARREAEHLAAEAEAAGLSVRLVRADAYPTRELASERLLYVVISTQGEGDPPDDAIGLVEFLSSRRAPKVPELKYAVLGLG
DSSYADFCGIARRIDERLAELGGSRVQPRGEADLDIDSVALPWRAQALTHAREQLKGGLHSATVTPLRSSPATPVWSHQQ
PFAAELLSNQIISGRDFKGPGFRVYAAPGKRVRHLEFSLQGSGLSYEPGDALGIRHRNPPALVDAVLQTLRLDGDAAVTI
GEQTLELHAWLATQRELTKLSRPFLTAHAERAGAQELQALLAPTQTAGLASLLADHQVIDVLRRWPADWDHAGLLAALRP
LTPRLYSVASSRKRVGDEVHLTVDEVTYQAHGHAHLGAASGFLAALGEGDTAPVYIEPNERFRVPADADRDILMIGPGTG
VAPFRGFVQERAETGAKGRNWLFFGAQHFNTDFLYQAEWQLALRRGELHALDLAFSRDQAEKLYVQHRLRARGAEVYAWL
QGGAHVYVCGATSMGKDVHAALLDIVATHGAQDAEAAAAYLTQLQVEGRYARDVY

Sequences:

>Translated_615_residues
MTAASSALPPSPLPDERKVLLDRLVDGLDTASLWWLSGYAAGLAQGHPPRSLAVLPGGQAHPLAQEGQRLTVVYGSQTGN
ARREAEHLAAEAEAAGLSVRLVRADAYPTRELASERLLYVVISTQGEGDPPDDAIGLVEFLSSRRAPKVPELKYAVLGLG
DSSYADFCGIARRIDERLAELGGSRVQPRGEADLDIDSVALPWRAQALTHAREQLKGGLHSATVTPLRSSPATPVWSHQQ
PFAAELLSNQIISGRDFKGPGFRVYAAPGKRVRHLEFSLQGSGLSYEPGDALGIRHRNPPALVDAVLQTLRLDGDAAVTI
GEQTLELHAWLATQRELTKLSRPFLTAHAERAGAQELQALLAPTQTAGLASLLADHQVIDVLRRWPADWDHAGLLAALRP
LTPRLYSVASSRKRVGDEVHLTVDEVTYQAHGHAHLGAASGFLAALGEGDTAPVYIEPNERFRVPADADRDILMIGPGTG
VAPFRGFVQERAETGAKGRNWLFFGAQHFNTDFLYQAEWQLALRRGELHALDLAFSRDQAEKLYVQHRLRARGAEVYAWL
QGGAHVYVCGATSMGKDVHAALLDIVATHGAQDAEAAAAYLTQLQVEGRYARDVY
>Mature_614_residues
TAASSALPPSPLPDERKVLLDRLVDGLDTASLWWLSGYAAGLAQGHPPRSLAVLPGGQAHPLAQEGQRLTVVYGSQTGNA
RREAEHLAAEAEAAGLSVRLVRADAYPTRELASERLLYVVISTQGEGDPPDDAIGLVEFLSSRRAPKVPELKYAVLGLGD
SSYADFCGIARRIDERLAELGGSRVQPRGEADLDIDSVALPWRAQALTHAREQLKGGLHSATVTPLRSSPATPVWSHQQP
FAAELLSNQIISGRDFKGPGFRVYAAPGKRVRHLEFSLQGSGLSYEPGDALGIRHRNPPALVDAVLQTLRLDGDAAVTIG
EQTLELHAWLATQRELTKLSRPFLTAHAERAGAQELQALLAPTQTAGLASLLADHQVIDVLRRWPADWDHAGLLAALRPL
TPRLYSVASSRKRVGDEVHLTVDEVTYQAHGHAHLGAASGFLAALGEGDTAPVYIEPNERFRVPADADRDILMIGPGTGV
APFRGFVQERAETGAKGRNWLFFGAQHFNTDFLYQAEWQLALRRGELHALDLAFSRDQAEKLYVQHRLRARGAEVYAWLQ
GGAHVYVCGATSMGKDVHAALLDIVATHGAQDAEAAAAYLTQLQVEGRYARDVY

Specific function: Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow f

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 flavodoxin-like domain [H]

Homologues:

Organism=Homo sapiens, GI127139033, Length=618, Percent_Identity=28.4789644012945, Blast_Score=221, Evalue=2e-57,
Organism=Homo sapiens, GI7657393, Length=612, Percent_Identity=31.6993464052288, Blast_Score=215, Evalue=8e-56,
Organism=Homo sapiens, GI24041029, Length=604, Percent_Identity=31.4569536423841, Blast_Score=214, Evalue=2e-55,
Organism=Homo sapiens, GI221316709, Length=612, Percent_Identity=31.6993464052288, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI221316705, Length=621, Percent_Identity=31.2399355877617, Blast_Score=208, Evalue=1e-53,
Organism=Homo sapiens, GI221316707, Length=537, Percent_Identity=32.0297951582868, Blast_Score=201, Evalue=2e-51,
Organism=Homo sapiens, GI40254422, Length=656, Percent_Identity=28.3536585365854, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI10835173, Length=649, Percent_Identity=25.57781201849, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI169790956, Length=402, Percent_Identity=28.3582089552239, Blast_Score=130, Evalue=5e-30,
Organism=Homo sapiens, GI169790958, Length=402, Percent_Identity=28.3582089552239, Blast_Score=129, Evalue=6e-30,
Organism=Escherichia coli, GI1789123, Length=621, Percent_Identity=42.512077294686, Blast_Score=454, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17554134, Length=610, Percent_Identity=28.0327868852459, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17566446, Length=592, Percent_Identity=26.1824324324324, Blast_Score=129, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI17531441, Length=390, Percent_Identity=26.6666666666667, Blast_Score=97, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32563863, Length=125, Percent_Identity=38.4, Blast_Score=83, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6321832, Length=643, Percent_Identity=27.2161741835148, Blast_Score=176, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6321143, Length=372, Percent_Identity=28.2258064516129, Blast_Score=130, Evalue=7e-31,
Organism=Drosophila melanogaster, GI17137192, Length=624, Percent_Identity=28.525641025641, Blast_Score=205, Evalue=6e-53,
Organism=Drosophila melanogaster, GI24582192, Length=526, Percent_Identity=26.615969581749, Blast_Score=172, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24660907, Length=584, Percent_Identity=28.7671232876712, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24660903, Length=584, Percent_Identity=28.7671232876712, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24583543, Length=665, Percent_Identity=26.7669172932331, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI78706876, Length=665, Percent_Identity=26.7669172932331, Blast_Score=166, Evalue=6e-41,
Organism=Drosophila melanogaster, GI78706872, Length=662, Percent_Identity=26.7371601208459, Blast_Score=166, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010199
- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001094
- InterPro:   IPR008254
- InterPro:   IPR001709
- InterPro:   IPR023173
- InterPro:   IPR001433
- InterPro:   IPR017938 [H]

Pfam domain/function: PF00667 FAD_binding_1; PF00258 Flavodoxin_1; PF00175 NAD_binding_1 [H]

EC number: =1.8.1.2 [H]

Molecular weight: Translated: 66559; Mature: 66427

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50902 FLAVODOXIN_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAASSALPPSPLPDERKVLLDRLVDGLDTASLWWLSGYAAGLAQGHPPRSLAVLPGGQA
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
HPLAQEGQRLTVVYGSQTGNARREAEHLAAEAEAAGLSVRLVRADAYPTRELASERLLYV
CCHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHCCCEEEE
VISTQGEGDPPDDAIGLVEFLSSRRAPKVPELKYAVLGLGDSSYADFCGIARRIDERLAE
EEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
LGGSRVQPRGEADLDIDSVALPWRAQALTHAREQLKGGLHSATVTPLRSSPATPVWSHQQ
HCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCC
PFAAELLSNQIISGRDFKGPGFRVYAAPGKRVRHLEFSLQGSGLSYEPGDALGIRHRNPP
CHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCH
ALVDAVLQTLRLDGDAAVTIGEQTLELHAWLATQRELTKLSRPFLTAHAERAGAQELQAL
HHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHH
LAPTQTAGLASLLADHQVIDVLRRWPADWDHAGLLAALRPLTPRLYSVASSRKRVGDEVH
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEE
LTVDEVTYQAHGHAHLGAASGFLAALGEGDTAPVYIEPNERFRVPADADRDILMIGPGTG
EEEEHEEEECCCCEECCHHHHHHHCCCCCCCCCEEECCCCCEECCCCCCCCEEEECCCCC
VAPFRGFVQERAETGAKGRNWLFFGAQHFNTDFLYQAEWQLALRRGELHALDLAFSRDQA
CHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCEEEEHHHHHHHHCCCEEEEEEECCHHHH
EKLYVQHRLRARGAEVYAWLQGGAHVYVCGATSMGKDVHAALLDIVATHGAQDAEAAAAY
HHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
LTQLQVEGRYARDVY
HHHHHCCCCHHCCCC
>Mature Secondary Structure 
TAASSALPPSPLPDERKVLLDRLVDGLDTASLWWLSGYAAGLAQGHPPRSLAVLPGGQA
CCCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCCC
HPLAQEGQRLTVVYGSQTGNARREAEHLAAEAEAAGLSVRLVRADAYPTRELASERLLYV
CCHHHCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHCCCEEEE
VISTQGEGDPPDDAIGLVEFLSSRRAPKVPELKYAVLGLGDSSYADFCGIARRIDERLAE
EEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHH
LGGSRVQPRGEADLDIDSVALPWRAQALTHAREQLKGGLHSATVTPLRSSPATPVWSHQQ
HCCCCCCCCCCCCCCCCCEECCHHHHHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCCC
PFAAELLSNQIISGRDFKGPGFRVYAAPGKRVRHLEFSLQGSGLSYEPGDALGIRHRNPP
CHHHHHHHHHCCCCCCCCCCCEEEEECCCCEEEEEEEEEECCCCCCCCCCCCCCCCCCCH
ALVDAVLQTLRLDGDAAVTIGEQTLELHAWLATQRELTKLSRPFLTAHAERAGAQELQAL
HHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHHHHH
LAPTQTAGLASLLADHQVIDVLRRWPADWDHAGLLAALRPLTPRLYSVASSRKRVGDEVH
HCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCEEE
LTVDEVTYQAHGHAHLGAASGFLAALGEGDTAPVYIEPNERFRVPADADRDILMIGPGTG
EEEEHEEEECCCCEECCHHHHHHHCCCCCCCCCEEECCCCCEECCCCCCCCEEEECCCCC
VAPFRGFVQERAETGAKGRNWLFFGAQHFNTDFLYQAEWQLALRRGELHALDLAFSRDQA
CHHHHHHHHHHHHCCCCCCEEEEEEHHHCCCCEEEEHHHHHHHHCCCEEEEEEECCHHHH
EKLYVQHRLRARGAEVYAWLQGGAHVYVCGATSMGKDVHAALLDIVATHGAQDAEAAAAY
HHHHHHHHHHHCCCEEEEEEECCCEEEEEECCCCCCHHHHHHHHHHHHCCCCHHHHHHHH
LTQLQVEGRYARDVY
HHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA