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The map label for this gene is colR [H]

Identifier: 21243976

GI number: 21243976

Start: 3831602

End: 3832279

Strand: Reverse

Name: colR [H]

Synonym: XAC3250

Alternate gene names: 21243976

Gene position: 3832279-3831602 (Counterclockwise)

Preceding gene: 21243977

Following gene: 21243975

Centisome position: 74.05

GC content: 63.86

Gene sequence:

>678_bases
GTGCGAATTCTAGTAATTGAAGACAACAGCGATATCGCCGCAAATCTTGGCGATTACCTCGAAGACCGGGGTCACACGGT
GGACTTCGCCGCCGACGGGGTGACTGGCCTCCACCTTGCCGTGGTGCACGAGTTCGATGCCATCGTGCTCGACCTCAACC
TGCCTGGCATGGATGGCATCGAGGTCTGCCGCAAGCTGCGCAACGAGGCGCGCAAGCAGACCCCGGTGTTGATGCTGACC
GCGCGCGACTCGCTGGACAACAAGCTGGCCGGCTTCGACTCCGGCGCCGACGACTATCTGATCAAGCCGTTCGCGCTGCA
GGAAGTGGAAGTGCGCCTCAACGCGCTATCGCGTCGCGGCAAGGGCGTGCACACCCGCGTGCTGGAAACCGGCGATCTGG
AATACAACCTGGATACGCTGGAAGTGCGTCGCCGCGGCAAGCTGCTGCAGCTCAACCCCACTGCGCTGAAGATCCTGCAG
GCGCTGATGGAAGCCTCGCCGGCGGTGGTCACGCGCCAGGAACTGGAAACCCGCGTGTGGGGCGAAGAACTGCCCGACTC
CGATTCGTTGCGCGTGCATATCCACGGCCTGCGCGCCGTGGTCGACAAGCCGTTCGATGTGCCGATGATCCAGACCCGCC
ACGGCATCGGCTACCGCATCGCCTCGCCCGATGCCTGA

Upstream 100 bases:

>100_bases
CAGTGCATGACGGCTGCCCAGCGGCGCCGTCAGACCACGGTGAGTCAAGACGAAATTTCTCGGCGCCAGCGCTAAAGACA
GCTTAACGAACGAGGTTCCA

Downstream 100 bases:

>100_bases
AAGTACGAGCGAGACGCGGCCGGCGCGCCGGCGCGGCCGCTATCGGCGGCGCCTGCGCAGCCGCATCATCCTGTCGTTCG
TGTTGTTGGGCTTCTGCCTG

Product: two-component system regulatory protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MRILVIEDNSDIAANLGDYLEDRGHTVDFAADGVTGLHLAVVHEFDAIVLDLNLPGMDGIEVCRKLRNEARKQTPVLMLT
ARDSLDNKLAGFDSGADDYLIKPFALQEVEVRLNALSRRGKGVHTRVLETGDLEYNLDTLEVRRRGKLLQLNPTALKILQ
ALMEASPAVVTRQELETRVWGEELPDSDSLRVHIHGLRAVVDKPFDVPMIQTRHGIGYRIASPDA

Sequences:

>Translated_225_residues
MRILVIEDNSDIAANLGDYLEDRGHTVDFAADGVTGLHLAVVHEFDAIVLDLNLPGMDGIEVCRKLRNEARKQTPVLMLT
ARDSLDNKLAGFDSGADDYLIKPFALQEVEVRLNALSRRGKGVHTRVLETGDLEYNLDTLEVRRRGKLLQLNPTALKILQ
ALMEASPAVVTRQELETRVWGEELPDSDSLRVHIHGLRAVVDKPFDVPMIQTRHGIGYRIASPDA
>Mature_225_residues
MRILVIEDNSDIAANLGDYLEDRGHTVDFAADGVTGLHLAVVHEFDAIVLDLNLPGMDGIEVCRKLRNEARKQTPVLMLT
ARDSLDNKLAGFDSGADDYLIKPFALQEVEVRLNALSRRGKGVHTRVLETGDLEYNLDTLEVRRRGKLLQLNPTALKILQ
ALMEASPAVVTRQELETRVWGEELPDSDSLRVHIHGLRAVVDKPFDVPMIQTRHGIGYRIASPDA

Specific function: Member of the three-protein two-component system HK1/HK2/tcrA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=35.8744394618834, Blast_Score=140, Evalue=9e-35,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=33.4801762114537, Blast_Score=138, Evalue=2e-34,
Organism=Escherichia coli, GI1789402, Length=223, Percent_Identity=38.5650224215247, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1790552, Length=230, Percent_Identity=36.0869565217391, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=219, Percent_Identity=31.5068493150685, Blast_Score=110, Evalue=7e-26,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=32.5892857142857, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=33.3333333333333, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789809, Length=233, Percent_Identity=31.7596566523605, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=30.8035714285714, Blast_Score=97, Evalue=7e-22,
Organism=Escherichia coli, GI1790860, Length=223, Percent_Identity=32.7354260089686, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1790863, Length=230, Percent_Identity=29.1304347826087, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=31.6017316017316, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=27.5109170305677, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1788550, Length=170, Percent_Identity=29.4117647058824, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788713, Length=118, Percent_Identity=33.0508474576271, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1788191, Length=121, Percent_Identity=31.404958677686, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=193, Percent_Identity=29.5336787564767, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25022; Mature: 25022

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVIEDNSDIAANLGDYLEDRGHTVDFAADGVTGLHLAVVHEFDAIVLDLNLPGMDGI
CEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCEEEEEECCCCCCHH
EVCRKLRNEARKQTPVLMLTARDSLDNKLAGFDSGADDYLIKPFALQEVEVRLNALSRRG
HHHHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCC
KGVHTRVLETGDLEYNLDTLEVRRRGKLLQLNPTALKILQALMEASPAVVTRQELETRVW
CCCEEEEEECCCCEECCHHHHHHHCCCEEEECHHHHHHHHHHHHCCCCEEEHHHHHHHHC
GEELPDSDSLRVHIHGLRAVVDKPFDVPMIQTRHGIGYRIASPDA
CCCCCCCCCEEEEEEEEHHHHCCCCCCCEEEECCCCCEEECCCCC
>Mature Secondary Structure
MRILVIEDNSDIAANLGDYLEDRGHTVDFAADGVTGLHLAVVHEFDAIVLDLNLPGMDGI
CEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCCCCEEEEEEECCCEEEEEECCCCCCHH
EVCRKLRNEARKQTPVLMLTARDSLDNKLAGFDSGADDYLIKPFALQEVEVRLNALSRRG
HHHHHHHHHHHHCCCEEEEEECCCCCCHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHCC
KGVHTRVLETGDLEYNLDTLEVRRRGKLLQLNPTALKILQALMEASPAVVTRQELETRVW
CCCEEEEEECCCCEECCHHHHHHHCCCEEEECHHHHHHHHHHHHCCCCEEEHHHHHHHHC
GEELPDSDSLRVHIHGLRAVVDKPFDVPMIQTRHGIGYRIASPDA
CCCCCCCCCEEEEEEEEHHHHCCCCCCCEEEECCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230 [H]