Click here to switch to the map view.

The map label for this gene is cobU [H]

Identifier: 21243913

GI number: 21243913

Start: 3750130

End: 3750651

Strand: Reverse

Name: cobU [H]

Synonym: XAC3187

Alternate gene names: 21243913

Gene position: 3750651-3750130 (Counterclockwise)

Preceding gene: 21243914

Following gene: 21243912

Centisome position: 72.47

GC content: 65.9

Gene sequence:

>522_bases
ATGCAGCACCTGATTCTTGGCGGCGCCCGTTCGGGCAAGAGCGCACTGGCCGAGCGCATCGCGGCAGCGTCCGGGCGCGC
AGTGACCTACCTGGCTACAGCGCAAGCCTTCGATGAGGAAATGCACCGGCGCATTGCCCATCACCGCAGCCAACGCCCAG
CGCATTGGCAGTGCGTGGAAGAGCCCATCGCGCTGGCGGCAAGCCTGCAGGCGCATGCCGCGCCGGATCGCTGCGTGCTG
GTGGATTGCCTGACCCTGTGGCTGAGCAACCTGCTTGGTCACCCGGATGCGGACGTATTCGCGCGCGAGCGCGACGCACT
GCTGGCAACGCTGCCGCAGTTGCCGGGGCAGATCCTGCTGGTCAGCAACGAAGTGGGGCAGGGCATCGTGCCGTTGGGTG
AACTCACGCGTCGGTTTGTGGACGAGGCTGGCTGGCTGCATCAGGCATTGGCGCTACAGTGCGAGCGTGTGGTGTTGGTG
GTGGCAGGGTTGCCGATGGTGTTGAAAGGAGAGCGCGTGTGA

Upstream 100 bases:

>100_bases
TTGCCGCGCTACGCGAAGCCAGCCTGGAACGTCTGGCCGATGCGGTGCACACGCATCTGGATACCGCCGCACTGACACGC
CTCATCAGCAGGGAGGCGGC

Downstream 100 bases:

>100_bases
GGAGCGATTGGATCTTTGGTGCCTGCGCAGTGCCGGACGCGCGCATGCGCTCTGCCGCGCTTGCCCGGCAGGAACAGCTG
ACCAAGCCGCCCGGCGCGCT

Product: adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase

Products: NA

Alternate protein names: Adenosylcobinamide kinase; Adenosylcobinamide-phosphate guanylyltransferase [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MQHLILGGARSGKSALAERIAAASGRAVTYLATAQAFDEEMHRRIAHHRSQRPAHWQCVEEPIALAASLQAHAAPDRCVL
VDCLTLWLSNLLGHPDADVFARERDALLATLPQLPGQILLVSNEVGQGIVPLGELTRRFVDEAGWLHQALALQCERVVLV
VAGLPMVLKGERV

Sequences:

>Translated_173_residues
MQHLILGGARSGKSALAERIAAASGRAVTYLATAQAFDEEMHRRIAHHRSQRPAHWQCVEEPIALAASLQAHAAPDRCVL
VDCLTLWLSNLLGHPDADVFARERDALLATLPQLPGQILLVSNEVGQGIVPLGELTRRFVDEAGWLHQALALQCERVVLV
VAGLPMVLKGERV
>Mature_173_residues
MQHLILGGARSGKSALAERIAAASGRAVTYLATAQAFDEEMHRRIAHHRSQRPAHWQCVEEPIALAASLQAHAAPDRCVL
VDCLTLWLSNLLGHPDADVFARERDALLATLPQLPGQILLVSNEVGQGIVPLGELTRRFVDEAGWLHQALALQCERVVLV
VAGLPMVLKGERV

Specific function: Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate [H]

COG id: COG2087

COG function: function code H; Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788302, Length=182, Percent_Identity=40.6593406593407, Blast_Score=117, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003203 [H]

Pfam domain/function: PF02283 CobU [H]

EC number: =2.7.1.156; =2.7.7.62 [H]

Molecular weight: Translated: 18796; Mature: 18796

Theoretical pI: Translated: 6.95; Mature: 6.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHLILGGARSGKSALAERIAAASGRAVTYLATAQAFDEEMHRRIAHHRSQRPAHWQCVE
CCCEEECCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EPIALAASLQAHAAPDRCVLVDCLTLWLSNLLGHPDADVFARERDALLATLPQLPGQILL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
VSNEVGQGIVPLGELTRRFVDEAGWLHQALALQCERVVLVVAGLPMVLKGERV
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCC
>Mature Secondary Structure
MQHLILGGARSGKSALAERIAAASGRAVTYLATAQAFDEEMHRRIAHHRSQRPAHWQCVE
CCCEEECCCCCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
EPIALAASLQAHAAPDRCVLVDCLTLWLSNLLGHPDADVFARERDALLATLPQLPGQILL
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEE
VSNEVGQGIVPLGELTRRFVDEAGWLHQALALQCERVVLVVAGLPMVLKGERV
EECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]