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The map label for this gene is yceE [C]

Identifier: 21243905

GI number: 21243905

Start: 3740675

End: 3741871

Strand: Direct

Name: yceE [C]

Synonym: XAC3179

Alternate gene names: 21243905

Gene position: 3740675-3741871 (Clockwise)

Preceding gene: 77748704

Following gene: 21243906

Centisome position: 72.28

GC content: 68.5

Gene sequence:

>1197_bases
ATGAGGCGCATCCTGGGTCCGGTACTGGCTGCGCATTATCTGGCGGCATTCACGGCGCTGGGCATGCCGCTGTTTCTGCC
GCAGGTCTTGGCCGAACTCGCACCGTCGGCCGCCGTGGGCTGGAGCGGCGTGCTGTATGTATTGCCCACGCTTTGCACCG
CGCTGACGGCAAGCACCTGGGGGCGTTGGGCGGACCGCAATGGACGCAAGCGTTCGCTGCTGCGCGCACAACTGGGCCTG
GCGCTGGGCTTTGCGATTGCCGGCTTCGCGCCGTCGCTGACCTGGCTGGTGATCGGCCTGATCGTACAGGGCACCTGTGG
CGGTTCGCTGGCGGCGGCAAATGCGTATCTGGCCAGCCAGCCGCAGGCCGGCCCGTTGGCGCGTGCGTTGGACTGGACAC
AGTATTCGGCCCGGCTTGCCATGGTGAGTGCACCTGCACTGCTGGGCCTGGCACTGGCGCTGGGCCCTGCGCAATCGCTG
TATCGCGCACTGGCGTTGCTGCCATTGATTGCGTTTGCGTTGACGTGGCGCCTGCCGGCCGATCAGCCTGCTGCGCGAGA
ACCCGCTGCCGGCACACCTGCTACGTCCTTGAAGCACGCCGCTTCATCGCCTGCATCGCCGCGCACCGTTGCCGCGACCT
CGTGGCCAGCCCTGCTGCTCGCCCAGTTCTTGTTCTGCTTCGCGATGGTGGTGACGTTCCCGTATTTCATCCCGTACGCG
CTCGCGCGCGGCGCCGGCCACGATGCGCTTGCCGGCCTGCTCTACAGCCTGCCGCATCTGGTGTATCTGGTGGTGCTGCC
GTGGTGGCGACGCGGCGATGGCGAGGCGTGGCTGGTACCGGGCCTGGCGTTGTTCGCGGCGGCCTGCGTGTGGCAGGCGC
TGTTGCACGATGCGCTCGCACTGGCAGCAGCGCGGCTGTTGTTCGGCTTCGGCATGCTGTTCGGGCTGCGTGGGCTCAAC
CGCAGCTTGGCGCACATCGCCAGCGGGCATAGCGCCGGGCGCCTGTTCGGCCGCTTCGATGCCTGCGGCAAATGGGCCGG
TGTGTTCGCCGGTGCCGCTGCCGGCGCATTGGCACAGGCGTCCGGCCCCGCCACCCCTTTCCTGGCTGCCGCGCTGGCCG
CGGCCGCTGCTGCACTCACCGTCCTGGTGCGCTTCCCTTCGAGGAGAACTGCCGATGTCGCCGCACACGATGCATGA

Upstream 100 bases:

>100_bases
CCGACATCAACAAGTTCTACGGCGACAGCGCGCCCAATCCGTTCGGCGATGCGTTCGCCGATGCGCGACATCCGCCGCGC
AGGCAAGCGGGCGCGCCGCG

Downstream 100 bases:

>100_bases
CCCCTGGTACGACAGCATGGCCGACGCGCAGGCCTGCAGCTGCTGGTTGAACTGCTATCTGCGCGAATTCGCGATTCCGC
AGCATGCGGTGCAGTTCGAC

Product: transport protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MRRILGPVLAAHYLAAFTALGMPLFLPQVLAELAPSAAVGWSGVLYVLPTLCTALTASTWGRWADRNGRKRSLLRAQLGL
ALGFAIAGFAPSLTWLVIGLIVQGTCGGSLAAANAYLASQPQAGPLARALDWTQYSARLAMVSAPALLGLALALGPAQSL
YRALALLPLIAFALTWRLPADQPAAREPAAGTPATSLKHAASSPASPRTVAATSWPALLLAQFLFCFAMVVTFPYFIPYA
LARGAGHDALAGLLYSLPHLVYLVVLPWWRRGDGEAWLVPGLALFAAACVWQALLHDALALAAARLLFGFGMLFGLRGLN
RSLAHIASGHSAGRLFGRFDACGKWAGVFAGAAAGALAQASGPATPFLAAALAAAAAALTVLVRFPSRRTADVAAHDA

Sequences:

>Translated_398_residues
MRRILGPVLAAHYLAAFTALGMPLFLPQVLAELAPSAAVGWSGVLYVLPTLCTALTASTWGRWADRNGRKRSLLRAQLGL
ALGFAIAGFAPSLTWLVIGLIVQGTCGGSLAAANAYLASQPQAGPLARALDWTQYSARLAMVSAPALLGLALALGPAQSL
YRALALLPLIAFALTWRLPADQPAAREPAAGTPATSLKHAASSPASPRTVAATSWPALLLAQFLFCFAMVVTFPYFIPYA
LARGAGHDALAGLLYSLPHLVYLVVLPWWRRGDGEAWLVPGLALFAAACVWQALLHDALALAAARLLFGFGMLFGLRGLN
RSLAHIASGHSAGRLFGRFDACGKWAGVFAGAAAGALAQASGPATPFLAAALAAAAAALTVLVRFPSRRTADVAAHDA
>Mature_398_residues
MRRILGPVLAAHYLAAFTALGMPLFLPQVLAELAPSAAVGWSGVLYVLPTLCTALTASTWGRWADRNGRKRSLLRAQLGL
ALGFAIAGFAPSLTWLVIGLIVQGTCGGSLAAANAYLASQPQAGPLARALDWTQYSARLAMVSAPALLGLALALGPAQSL
YRALALLPLIAFALTWRLPADQPAAREPAAGTPATSLKHAASSPASPRTVAATSWPALLLAQFLFCFAMVVTFPYFIPYA
LARGAGHDALAGLLYSLPHLVYLVVLPWWRRGDGEAWLVPGLALFAAACVWQALLHDALALAAARLLFGFGMLFGLRGLN
RSLAHIASGHSAGRLFGRFDACGKWAGVFAGAAAGALAQASGPATPFLAAALAAAAAALTVLVRFPSRRTADVAAHDA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 41286; Mature: 41286

Theoretical pI: Translated: 10.72; Mature: 10.72

Prosite motif: PS00356 HTH_LACI_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRILGPVLAAHYLAAFTALGMPLFLPQVLAELAPSAAVGWSGVLYVLPTLCTALTASTW
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHH
GRWADRNGRKRSLLRAQLGLALGFAIAGFAPSLTWLVIGLIVQGTCGGSLAAANAYLASQ
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
PQAGPLARALDWTQYSARLAMVSAPALLGLALALGPAQSLYRALALLPLIAFALTWRLPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
DQPAAREPAAGTPATSLKHAASSPASPRTVAATSWPALLLAQFLFCFAMVVTFPYFIPYA
CCCCCCCCCCCCCHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LARGAGHDALAGLLYSLPHLVYLVVLPWWRRGDGEAWLVPGLALFAAACVWQALLHDALA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
LAAARLLFGFGMLFGLRGLNRSLAHIASGHSAGRLFGRFDACGKWAGVFAGAAAGALAQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGPATPFLAAALAAAAAALTVLVRFPSRRTADVAAHDA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRRILGPVLAAHYLAAFTALGMPLFLPQVLAELAPSAAVGWSGVLYVLPTLCTALTASTW
CCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHH
GRWADRNGRKRSLLRAQLGLALGFAIAGFAPSLTWLVIGLIVQGTCGGSLAAANAYLASQ
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
PQAGPLARALDWTQYSARLAMVSAPALLGLALALGPAQSLYRALALLPLIAFALTWRLPA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
DQPAAREPAAGTPATSLKHAASSPASPRTVAATSWPALLLAQFLFCFAMVVTFPYFIPYA
CCCCCCCCCCCCCHHHHHHHCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
LARGAGHDALAGLLYSLPHLVYLVVLPWWRRGDGEAWLVPGLALFAAACVWQALLHDALA
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHH
LAAARLLFGFGMLFGLRGLNRSLAHIASGHSAGRLFGRFDACGKWAGVFAGAAAGALAQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SGPATPFLAAALAAAAAALTVLVRFPSRRTADVAAHDA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]