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The map label for this gene is laaA [H]

Identifier: 21243714

GI number: 21243714

Start: 3492487

End: 3493428

Strand: Reverse

Name: laaA [H]

Synonym: XAC2987

Alternate gene names: 21243714

Gene position: 3493428-3492487 (Counterclockwise)

Preceding gene: 21243715

Following gene: 21243713

Centisome position: 67.5

GC content: 66.35

Gene sequence:

>942_bases
ATGCAGTGCACCGAGGGTTACGTCGAATTCCGCGGCTACCGCACCTGGTACCGCATTACCGGCGACCTGTGCGCGGATGC
CTGCCCGCTACTGGTGCTGCACGGCGGTCCCGGGTGCACGCACGACTACGTGGACAGCTTCAAGGACCTGGCGGCCAACG
GCCGCGCGGTGATCCACTACGACCAGCTGGGCAACGGCAACTCCACCCATCTGCGCAATGCCGAGCCAGGCTTCTGGACA
GTGGGGCTGTTCCTGGACGAGCTGCAGACGCTGATCGCGCATCTGGGGCTGTCGCAATACGCATTGCTGGGCCAGTCCTG
GGGCGGAATGCTGGCAGCCGAACATGCGGTGCGCCGTCCGGCCGGCCTGCGGGCGCTGGTGATCGCCAATTCGCCCGCCT
CGATGGGGTTGTGGCGCGCTGCTGCGCTGCGCCTGCGCGCGCGCCTGCCCGAGGATATCCAGGCCGCACTGGACGAGCAC
GAAGCCGCCGGTACGCTGGATCATCCGGCCTATCGCGCCGCCAGTCAGGTGTTCTACGCGCAGCACGTGTGTCGCGTGCT
GCCGTGGCCTGCCGAGGTCGCGCGTACGTTTGCCGCCATCGACGCCGATCCAACCGTGTATCACGCCATGAACGGCCCGA
CCGAATTCCACGTGGTGGGCAGCCTGCGCAACTGGAGCATCATCGAGCGCCTGCACCGCATCACCGCACCCACGCTGGTG
CTCTCTGGCAAGTACGATGAAGCCACGCCGGAAACCGTCGAGCCCTATGCGCGGTTGATTCCGGATGCGCGCTGGCACGT
GTTCGCCAACTCCAGCCACATGCCGCACGTGGAAGAACGCGTGGCGTGCATGCGCCTGGTCGGCAATTTCCTGGACGATC
AGACACCGTGGCCCGGTGGCCAGATATTGCGCTCGTCAGCACTGGCCAATCGCGCTGTTTGA

Upstream 100 bases:

>100_bases
CGCATCCGGGCGCGCCCAAACCTGTGAAATTTGCCAGTTAACGCCGCTCGGCGCGCTCGCTAGGCTCGGGCCTCATCATT
GCCGTAGGCAGGCGCAGGTC

Downstream 100 bases:

>100_bases
GCGTGCAGGGTGCGTGTGCGATGGCCAGCGGGCCGATCGACCGCACTGCGTTTAGCTGCCTGCCTGCTGCGATGATGCGG
CGATGGGCGGACACCATCAA

Product: proline imino-peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 313

Protein sequence:

>313_residues
MQCTEGYVEFRGYRTWYRITGDLCADACPLLVLHGGPGCTHDYVDSFKDLAANGRAVIHYDQLGNGNSTHLRNAEPGFWT
VGLFLDELQTLIAHLGLSQYALLGQSWGGMLAAEHAVRRPAGLRALVIANSPASMGLWRAAALRLRARLPEDIQAALDEH
EAAGTLDHPAYRAASQVFYAQHVCRVLPWPAEVARTFAAIDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHRITAPTLV
LSGKYDEATPETVEPYARLIPDARWHVFANSSHMPHVEERVACMRLVGNFLDDQTPWPGGQILRSSALANRAV

Sequences:

>Translated_313_residues
MQCTEGYVEFRGYRTWYRITGDLCADACPLLVLHGGPGCTHDYVDSFKDLAANGRAVIHYDQLGNGNSTHLRNAEPGFWT
VGLFLDELQTLIAHLGLSQYALLGQSWGGMLAAEHAVRRPAGLRALVIANSPASMGLWRAAALRLRARLPEDIQAALDEH
EAAGTLDHPAYRAASQVFYAQHVCRVLPWPAEVARTFAAIDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHRITAPTLV
LSGKYDEATPETVEPYARLIPDARWHVFANSSHMPHVEERVACMRLVGNFLDDQTPWPGGQILRSSALANRAV
>Mature_313_residues
MQCTEGYVEFRGYRTWYRITGDLCADACPLLVLHGGPGCTHDYVDSFKDLAANGRAVIHYDQLGNGNSTHLRNAEPGFWT
VGLFLDELQTLIAHLGLSQYALLGQSWGGMLAAEHAVRRPAGLRALVIANSPASMGLWRAAALRLRARLPEDIQAALDEH
EAAGTLDHPAYRAASQVFYAQHVCRVLPWPAEVARTFAAIDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHRITAPTLV
LSGKYDEATPETVEPYARLIPDARWHVFANSSHMPHVEERVACMRLVGNFLDDQTPWPGGQILRSSALANRAV

Specific function: Hydrolyzes L-prolinamide, L-proline-p-nitroanilide, L- alaninamide, L-methioninamide, piperidine-2-carboxamide and piperazine-2-carboxamide. Has a much lower activity towards piperazine-2-tert-butylcarboxamide. Does not hydrolyze dipeptides and D-prolinam

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005945
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.5.1.101 [H]

Molecular weight: Translated: 34539; Mature: 34539

Theoretical pI: Translated: 6.67; Mature: 6.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQCTEGYVEFRGYRTWYRITGDLCADACPLLVLHGGPGCTHDYVDSFKDLAANGRAVIHY
CCCCCCHHHHHCEEEEEEEEHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEE
DQLGNGNSTHLRNAEPGFWTVGLFLDELQTLIAHLGLSQYALLGQSWGGMLAAEHAVRRP
CCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCC
AGLRALVIANSPASMGLWRAAALRLRARLPEDIQAALDEHEAAGTLDHPAYRAASQVFYA
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
QHVCRVLPWPAEVARTFAAIDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHRITAPTLV
HHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCEEE
LSGKYDEATPETVEPYARLIPDARWHVFANSSHMPHVEERVACMRLVGNFLDDQTPWPGG
EECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCH
QILRSSALANRAV
HHHHHHHHHHCCC
>Mature Secondary Structure
MQCTEGYVEFRGYRTWYRITGDLCADACPLLVLHGGPGCTHDYVDSFKDLAANGRAVIHY
CCCCCCHHHHHCEEEEEEEEHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEE
DQLGNGNSTHLRNAEPGFWTVGLFLDELQTLIAHLGLSQYALLGQSWGGMLAAEHAVRRP
CCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCHHHHHHHHCCC
AGLRALVIANSPASMGLWRAAALRLRARLPEDIQAALDEHEAAGTLDHPAYRAASQVFYA
CCCEEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
QHVCRVLPWPAEVARTFAAIDADPTVYHAMNGPTEFHVVGSLRNWSIIERLHRITAPTLV
HHHHHHCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEEECCCCCHHHHHHHHHCCCEEE
LSGKYDEATPETVEPYARLIPDARWHVFANSSHMPHVEERVACMRLVGNFLDDQTPWPGG
EECCCCCCCCHHHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCH
QILRSSALANRAV
HHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA