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The map label for this gene is yieH [H]

Identifier: 21243610

GI number: 21243610

Start: 3383134

End: 3383811

Strand: Reverse

Name: yieH [H]

Synonym: XAC2883

Alternate gene names: 21243610

Gene position: 3383811-3383134 (Counterclockwise)

Preceding gene: 21243613

Following gene: 21243607

Centisome position: 65.38

GC content: 64.75

Gene sequence:

>678_bases
ATGGCGTACGAGCTACTGATCAGTGACTGTGATGGCGTTCTTGTCGACAGCGAGATATTGGCCGACCGGGTAATGCGTGA
GGCGCTGGCGTCTTTCGTGCCAAGCGAGCCGCTGGAACATCTGCTGGAAACCACCTTCGGGCAGACCACACGCGAGGTGT
TGCGGCGGGTGGAAGAGCGCTTTGCGCTGCGGTTGCCGGAGACGTTACTGGCGCAGATCCAGGTGCGCAGCGAGGCATTG
ATCCAGGCGCAGGTGCAGCCGATCGCAGGCGTACGCGAGGCGTTGGAGCAGATTCCGCTGCCGTTGGCGGTCGCCTCCAA
TAGCCGGCGCCACAATGTGATTGCCTCGGTGGAACGGGCCGGGCTCACCGCACGTGCGGCGGGACGTATTTTCAGCGCCG
ACATGGTGGAGCGGCCCAAGCCGGCACCGGACGTGTATCTGCTGGCGGCACGCACCGCCGGGGTCGCACCGGAGCGTTGT
CTGGTCATCGAAGACAGCCCGACCGGTGCAACGGCGGCCGTGACGGCCGGCATGCAGGTGGTGGGGTTTGCCGGTGCGAG
CCACATTCCACCGGGGCATGGCGATACCTTGCGCCGCATCGGTGTGCTTGAGGTGTTCGACGATATGCGTGATTTGCCTG
CGTTGTTTGCGCTGCTGGCGCAAAAGCGCGCCGGGTAA

Upstream 100 bases:

>100_bases
GCCGCGAGCGGCGACGGTATCCATCGCCACAGCCTGCTGCCCCACAGCCGACGGTCACACCGGGGCCGGCATAATGGCGC
TTTGCGAGCAGATGGGTGCA

Downstream 100 bases:

>100_bases
GGCGATAGCTTGGTGAGCGGAGTGTGCGGGGTACTCAGCGCTTGCGCGACACATAGTGGATCCGTCCATGGACGTTCTTG
CGTGTCATTCATGCAACCAA

Product: hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 225; Mature: 224

Protein sequence:

>225_residues
MAYELLISDCDGVLVDSEILADRVMREALASFVPSEPLEHLLETTFGQTTREVLRRVEERFALRLPETLLAQIQVRSEAL
IQAQVQPIAGVREALEQIPLPLAVASNSRRHNVIASVERAGLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPERC
LVIEDSPTGATAAVTAGMQVVGFAGASHIPPGHGDTLRRIGVLEVFDDMRDLPALFALLAQKRAG

Sequences:

>Translated_225_residues
MAYELLISDCDGVLVDSEILADRVMREALASFVPSEPLEHLLETTFGQTTREVLRRVEERFALRLPETLLAQIQVRSEAL
IQAQVQPIAGVREALEQIPLPLAVASNSRRHNVIASVERAGLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPERC
LVIEDSPTGATAAVTAGMQVVGFAGASHIPPGHGDTLRRIGVLEVFDDMRDLPALFALLAQKRAG
>Mature_224_residues
AYELLISDCDGVLVDSEILADRVMREALASFVPSEPLEHLLETTFGQTTREVLRRVEERFALRLPETLLAQIQVRSEALI
QAQVQPIAGVREALEQIPLPLAVASNSRRHNVIASVERAGLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPERCL
VIEDSPTGATAAVTAGMQVVGFAGASHIPPGHGDTLRRIGVLEVFDDMRDLPALFALLAQKRAG

Specific function: Catalyzes the dephosphorylation of the artificial chromogenic substrate p-nitrophenyl phosphate (pNPP) and of the natural substrates phosphoenolpyruvate and AMP [H]

COG id: COG0637

COG function: function code R; Predicted phosphatase/phosphohexomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1790151, Length=190, Percent_Identity=27.3684210526316, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789046, Length=182, Percent_Identity=31.3186813186813, Blast_Score=64, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17137324, Length=183, Percent_Identity=31.1475409836066, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: NA

Molecular weight: Translated: 24249; Mature: 24118

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYELLISDCDGVLVDSEILADRVMREALASFVPSEPLEHLLETTFGQTTREVLRRVEER
CCCEEEEECCCCEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHH
FALRLPETLLAQIQVRSEALIQAQVQPIAGVREALEQIPLPLAVASNSRRHNVIASVERA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHH
GLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPERCLVIEDSPTGATAAVTAGMQV
CCHHHHHCCHHHHHHHCCCCCCCCEEEEEEHHCCCCCCEEEEEECCCCCCHHHHHHCHHH
VGFAGASHIPPGHGDTLRRIGVLEVFDDMRDLPALFALLAQKRAG
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AYELLISDCDGVLVDSEILADRVMREALASFVPSEPLEHLLETTFGQTTREVLRRVEER
CCEEEEECCCCEEECHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHH
FALRLPETLLAQIQVRSEALIQAQVQPIAGVREALEQIPLPLAVASNSRRHNVIASVERA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHH
GLTARAAGRIFSADMVERPKPAPDVYLLAARTAGVAPERCLVIEDSPTGATAAVTAGMQV
CCHHHHHCCHHHHHHHCCCCCCCCEEEEEEHHCCCCCCEEEEEECCCCCCHHHHHHCHHH
VGFAGASHIPPGHGDTLRRIGVLEVFDDMRDLPALFALLAQKRAG
EEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]