Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 21243494

GI number: 21243494

Start: 3240181

End: 3241626

Strand: Reverse

Name: tldD [H]

Synonym: XAC2767

Alternate gene names: 21243494

Gene position: 3241626-3240181 (Counterclockwise)

Preceding gene: 21243496

Following gene: 21243492

Centisome position: 62.63

GC content: 68.4

Gene sequence:

>1446_bases
ATGACCGATAACGCTCTCACTCTGGCCGAAACCCGGCTGCTGCTTCCCTCCGGCCTGGACGCCGGCCATCTCGACCGCAC
CTTCGGCGCCCTGCTGGGCCCGGGCATCGACTTCGGCGATCTGTATTTCCAGCATTCGCGGCGCGAGAGCTGGAGCGTGG
AAGACGGCATCGTCAAGGACGGTGCGCACTCCATCGAGCAAGGCGTGGGCGTGCGCGCAATCGCCGGCGAGAAAACCGGC
TTCGCCTATTCCGACGATATCCATCGCGATGCCCTGCTCGAAGCAGCGCAGTCCGCGCGCGCGATCTCGCGCGAGGGCGG
CGCGCAATCCACCCGCTCGCTGGTGCGCGGCAGTGGCCGTGCGCTGTACCCGGCCACCGACCCGATCGACGACATGGACA
GCGCCACCAAGGTGGACCTGCTGCGCCGGATCGACCAATTCCTGCGCGCTGCCGACCCGCGCGTCAAGCAGGTGATGGTG
AGCCTGTCCGGCGGCGTGGACACGGTGCTGATCGCCCGCAGCGATGGCGTGCTGGCAGCGGACGTGCGCCCGCTGGTGCG
CTTGAACGTGCAGGTGATCGTCGAACAGGGCGGCCGGCGCGAATCCGGTTATTCCGGCGGCGGCGGGCGCTATGGCTATG
CCGACCTGTTCGCCGACGGCCGCCCGGAAGGCTTCGCGCGCGAAGCGCTGCGCCAGGCGCTGGTGAATCTGGATGCGATC
CCGGCGCCGGCCGGGGTGATGCCGGTAGTGCTCGGCCCGGGCTGGCCCGGCGTGCTGTTGCACGAGGCGGTGGGCCACGG
CCTGGAAGGCGACTTCAACCGCAAGGGCACCAGCGTCTACGCCGGGCGCATCGGCGAGCGCGTGGCCTCGCCGGGCGTGA
CCATCGTCGATGACGGCACCCTGGACGGCCGTCGCGGCTCGCTCAATATCGACGACGAAGGCACGCCCAGCCAGTGCACC
ACGCTGATCGAAGACGGCGTGCTGGTGGGTTACATGCAGGACAGCCACAACGCGCGCCTGATGGGCGTTGCGCCCACCGG
CAACGGCCGCCGCGAATCGTTCGCGCACCTGACCATGCCGCGCATGACCAATACCTACATGCGTGCCGGCCAGCACGACC
CGGAAGAGATGATCCGCTCGGTCAAGAAGGGCATCTATGCGGTGAACTTCGGCGGCGGCCAGGTCGACATCACCAGCGGC
AAGTACGTGTTCTCCGCGACCGAGGCCTACCTGATCGAAGACGGCAAGGTCACCGCACCGGTCAAGGGCGCCACCCTGAT
CGGCAACGGCCCGGAGACCATGCAGAAGGTACGCATGATCGGCAACGACCTGGCATTGGATGAAGGCGTGGGCGTGTGCG
GCAAGGACGGGCAGAGCGTGCCGGTCGGCGTCGGCCAGCCGTCGCTGTTGATCGACGGCATCACGGTTGGCGGAACGCAG
GCCTGA

Upstream 100 bases:

>100_bases
TGCGCGGGCGATCGGTGAAGAGCTGACCGACGATGATAGCTGCGCCGCATGTTCAGCCGAACGACTTGTCTCCCCGGCGT
CCGGGCCCCATCCTGACCGC

Downstream 100 bases:

>100_bases
GATGCGGGGAATCGGGAATCGGGATAGGGGAATCGCAGCGGCAGGAGCGCAGAGCAGCGCGTCGGGCCTTTGCCGTTTGC
CGGTTCAGCAGAGGGGAATC

Product: TldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTDNALTLAETRLLLPSGLDAGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKDGAHSIEQGVGVRAIAGEKTG
FAYSDDIHRDALLEAAQSARAISREGGAQSTRSLVRGSGRALYPATDPIDDMDSATKVDLLRRIDQFLRAADPRVKQVMV
SLSGGVDTVLIARSDGVLAADVRPLVRLNVQVIVEQGGRRESGYSGGGGRYGYADLFADGRPEGFAREALRQALVNLDAI
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTPSQCT
TLIEDGVLVGYMQDSHNARLMGVAPTGNGRRESFAHLTMPRMTNTYMRAGQHDPEEMIRSVKKGIYAVNFGGGQVDITSG
KYVFSATEAYLIEDGKVTAPVKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTQ
A

Sequences:

>Translated_481_residues
MTDNALTLAETRLLLPSGLDAGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKDGAHSIEQGVGVRAIAGEKTG
FAYSDDIHRDALLEAAQSARAISREGGAQSTRSLVRGSGRALYPATDPIDDMDSATKVDLLRRIDQFLRAADPRVKQVMV
SLSGGVDTVLIARSDGVLAADVRPLVRLNVQVIVEQGGRRESGYSGGGGRYGYADLFADGRPEGFAREALRQALVNLDAI
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTPSQCT
TLIEDGVLVGYMQDSHNARLMGVAPTGNGRRESFAHLTMPRMTNTYMRAGQHDPEEMIRSVKKGIYAVNFGGGQVDITSG
KYVFSATEAYLIEDGKVTAPVKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTQ
A
>Mature_480_residues
TDNALTLAETRLLLPSGLDAGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKDGAHSIEQGVGVRAIAGEKTGF
AYSDDIHRDALLEAAQSARAISREGGAQSTRSLVRGSGRALYPATDPIDDMDSATKVDLLRRIDQFLRAADPRVKQVMVS
LSGGVDTVLIARSDGVLAADVRPLVRLNVQVIVEQGGRRESGYSGGGGRYGYADLFADGRPEGFAREALRQALVNLDAIP
APAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTPSQCTT
LIEDGVLVGYMQDSHNARLMGVAPTGNGRRESFAHLTMPRMTNTYMRAGQHDPEEMIRSVKKGIYAVNFGGGQVDITSGK
YVFSATEAYLIEDGKVTAPVKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTQA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=479, Percent_Identity=62.2129436325678, Blast_Score=571, Evalue=1e-164,
Organism=Escherichia coli, GI1790682, Length=319, Percent_Identity=23.8244514106583, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 50709; Mature: 50578

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNALTLAETRLLLPSGLDAGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKD
CCCCCEEHHHHEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHC
GAHSIEQGVGVRAIAGEKTGFAYSDDIHRDALLEAAQSARAISREGGAQSTRSLVRGSGR
CHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
ALYPATDPIDDMDSATKVDLLRRIDQFLRAADPRVKQVMVSLSGGVDTVLIARSDGVLAA
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCEEEE
DVRPLVRLNVQVIVEQGGRRESGYSGGGGRYGYADLFADGRPEGFAREALRQALVNLDAI
CCCHHHHEEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCC
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGT
CCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEECCC
LDGRRGSLNIDDEGTPSQCTTLIEDGVLVGYMQDSHNARLMGVAPTGNGRRESFAHLTMP
CCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCCCCCHHHHEEECC
RMTNTYMRAGQHDPEEMIRSVKKGIYAVNFGGGQVDITSGKYVFSATEAYLIEDGKVTAP
HHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEEEEECCEEECC
VKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTQ
CCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
A
C
>Mature Secondary Structure 
TDNALTLAETRLLLPSGLDAGHLDRTFGALLGPGIDFGDLYFQHSRRESWSVEDGIVKD
CCCCEEHHHHEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCHHC
GAHSIEQGVGVRAIAGEKTGFAYSDDIHRDALLEAAQSARAISREGGAQSTRSLVRGSGR
CHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCC
ALYPATDPIDDMDSATKVDLLRRIDQFLRAADPRVKQVMVSLSGGVDTVLIARSDGVLAA
EECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCEEEE
DVRPLVRLNVQVIVEQGGRRESGYSGGGGRYGYADLFADGRPEGFAREALRQALVNLDAI
CCCHHHHEEEEEEEECCCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHHHHHHHHCCCCC
PAPAGVMPVVLGPGWPGVLLHEAVGHGLEGDFNRKGTSVYAGRIGERVASPGVTIVDDGT
CCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCCEEEHHHHHHHHCCCCCEEEECCC
LDGRRGSLNIDDEGTPSQCTTLIEDGVLVGYMQDSHNARLMGVAPTGNGRRESFAHLTMP
CCCCCCCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCCEEEEEECCCCCCCHHHHEEECC
RMTNTYMRAGQHDPEEMIRSVKKGIYAVNFGGGQVDITSGKYVFSATEAYLIEDGKVTAP
HHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEEEEECCEEECC
VKGATLIGNGPETMQKVRMIGNDLALDEGVGVCGKDGQSVPVGVGQPSLLIDGITVGGTQ
CCCCEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]