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The map label for this gene is yciK [H]

Identifier: 21243404

GI number: 21243404

Start: 3134861

End: 3135595

Strand: Reverse

Name: yciK [H]

Synonym: XAC2675

Alternate gene names: 21243404

Gene position: 3135595-3134861 (Counterclockwise)

Preceding gene: 21243405

Following gene: 21243403

Centisome position: 60.58

GC content: 69.25

Gene sequence:

>735_bases
GTGCAGGCCCAGTCGCAGTCGGCTGCCTTGTCGGGACGTGTCGTGCTGATCACCGGCGCCGCTGGTGGCCTTGGCGCCGC
TGCGGCGCAGGCATGCGCGGCGGCAGGCGCCACGGTGGTCCTGCTTGGTCGCAAGGTGCGCCCGCTGGAACGCATCTACG
ACGCGGTTGCAGCGCTGGGTGACGAGCCGCTGCTATATCCGCTGGATCTGGCCGGCGCCACGCCGGACGACTACGCCACG
CTTGCGCAACGGTTGCAGACCGAGCTTGGTGGCCTGCATGGCCTGCTGCACTGCGCCGCCGACTTTTCCGGCCTGACGCC
AACCGAACTCGTCTTACCTACCGATTTCGCACGCACCTTGCACGTCGACCTGACCGCGCGCGCCTGGCTGACCCAGGCAT
GCTTGCCGCTGTTGCGGCAGCAGGACGATGCGGCAGTCGTCTTCGTGGTGGACGACCCCGCGCGTGTGGGTCAGGCCTAT
TGGGGAGCGTATGGCGCCGCCCAGCATGCGCAGCGCGGCTTGATCGCCACCTTGCATCATGAAACCGCCGCCGGCCCGGT
GCGCGTCAGCGGCCTGCAGCCCGGCCCGATGCGCACCGCATTGCGCGCACGCGCTTTCACCCATCACGAAGACAACGACG
CGGTCGAGGCCGCACGTTACGCCCCTGCGTGCGTCGGCGTACTGTCAGCCGCGGGGGCGATGCATCGCGGTGCGATCTGG
AGTCCGCCGGTATGA

Upstream 100 bases:

>100_bases
TCCATGGCGAGCTGATCGGCGGCTGCGACATCACGCTGGAGCTGTTCGAAGCCGGCGAGCTCAAGCGCATCGTCAGCGAG
GCGTACCAGCCGTGAGTTCG

Downstream 100 bases:

>100_bases
CCATTCTTTCCGCGGCGCTGCTGCTGTTCCTGATTCTCGACCCGCTGGGCAACATTCCAGTGTTTCTCAGCGTGCTCAAG
CCGCTGCCGCCCAAGCGCCA

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MQAQSQSAALSGRVVLITGAAGGLGAAAAQACAAAGATVVLLGRKVRPLERIYDAVAALGDEPLLYPLDLAGATPDDYAT
LAQRLQTELGGLHGLLHCAADFSGLTPTELVLPTDFARTLHVDLTARAWLTQACLPLLRQQDDAAVVFVVDDPARVGQAY
WGAYGAAQHAQRGLIATLHHETAAGPVRVSGLQPGPMRTALRARAFTHHEDNDAVEAARYAPACVGVLSAAGAMHRGAIW
SPPV

Sequences:

>Translated_244_residues
MQAQSQSAALSGRVVLITGAAGGLGAAAAQACAAAGATVVLLGRKVRPLERIYDAVAALGDEPLLYPLDLAGATPDDYAT
LAQRLQTELGGLHGLLHCAADFSGLTPTELVLPTDFARTLHVDLTARAWLTQACLPLLRQQDDAAVVFVVDDPARVGQAY
WGAYGAAQHAQRGLIATLHHETAAGPVRVSGLQPGPMRTALRARAFTHHEDNDAVEAARYAPACVGVLSAAGAMHRGAIW
SPPV
>Mature_244_residues
MQAQSQSAALSGRVVLITGAAGGLGAAAAQACAAAGATVVLLGRKVRPLERIYDAVAALGDEPLLYPLDLAGATPDDYAT
LAQRLQTELGGLHGLLHCAADFSGLTPTELVLPTDFARTLHVDLTARAWLTQACLPLLRQQDDAAVVFVVDDPARVGQAY
WGAYGAAQHAQRGLIATLHHETAAGPVRVSGLQPGPMRTALRARAFTHHEDNDAVEAARYAPACVGVLSAAGAMHRGAIW
SPPV

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Escherichia coli, GI1787526, Length=207, Percent_Identity=36.231884057971, Blast_Score=112, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21358495, Length=215, Percent_Identity=30.6976744186047, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI21355319, Length=209, Percent_Identity=28.2296650717703, Blast_Score=71, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 25303; Mature: 25303

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAQSQSAALSGRVVLITGAAGGLGAAAAQACAAAGATVVLLGRKVRPLERIYDAVAALG
CCCCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCC
DEPLLYPLDLAGATPDDYATLAQRLQTELGGLHGLLHCAADFSGLTPTELVLPTDFARTL
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEE
HVDLTARAWLTQACLPLLRQQDDAAVVFVVDDPARVGQAYWGAYGAAQHAQRGLIATLHH
EEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECC
ETAAGPVRVSGLQPGPMRTALRARAFTHHEDNDAVEAARYAPACVGVLSAAGAMHRGAIW
CCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SPPV
CCCC
>Mature Secondary Structure
MQAQSQSAALSGRVVLITGAAGGLGAAAAQACAAAGATVVLLGRKVRPLERIYDAVAALG
CCCCCCCHHHCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHCC
DEPLLYPLDLAGATPDDYATLAQRLQTELGGLHGLLHCAADFSGLTPTELVLPTDFARTL
CCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEE
HVDLTARAWLTQACLPLLRQQDDAAVVFVVDDPARVGQAYWGAYGAAQHAQRGLIATLHH
EEEHHHHHHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHCCCEEEECC
ETAAGPVRVSGLQPGPMRTALRARAFTHHEDNDAVEAARYAPACVGVLSAAGAMHRGAIW
CCCCCCEEECCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SPPV
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]