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The map label for this gene is exuR [H]

Identifier: 21243326

GI number: 21243326

Start: 3056086

End: 3057207

Strand: Direct

Name: exuR [H]

Synonym: XAC2595

Alternate gene names: 21243326

Gene position: 3056086-3057207 (Clockwise)

Preceding gene: 21243297

Following gene: 21243330

Centisome position: 59.05

GC content: 66.67

Gene sequence:

>1122_bases
ATGACCATCAAGGGTAAAGCCACCTCGCTGGATATCGCCTACCTGGCCGGCGTGTCGCAGCCGACCGTGTCGCGCGCACT
CCGCGGCAGCCCGATGGTCAACGAGGAAACCCGCAAGCGCATCCTGCGCATCGCCCGCGAGCTGAACTACAAGGTCGACA
AGAACGCCTCCTCGCTACGGCTGCGCAATGCCGGCACGCTGGCACTGCTGTTCTTCGAAGACCCCACTGCCGACGACTCG
CTGATCAACCCGTTCTTCCATTCGATGCTGGGCTCGATCACCCGTGCCTGCGCGCTGCAGGGCTACGACCTGCTGGTGTC
GTTCCAGCAGTTGTCCAAGGATTGGCAGGCCGATTATGAAGACAGCAACAAGGCCGACGGCATCATCCTGCTGGGCTATG
GCGACTATCAGCAATCGCGCCAACGGCTGCAGCTGCTGGTCGAGCAAGGCACCCACTTCGTGCGCTGGGGCGCGGCCCTG
CCCGGCCAGCCCGGCATTTCGATCGGCAGCGACAATTACCAGGGCGGGCTGGACATTACCGACCATCTGCTGGCGCAGGG
CTGCCGGCGCATCGCGTTCCTCGGACACGCGTCCAACCACTACCCCGAATTCGAAGAACGCTACCGCGGCCATGCCACGG
CGCTGGCGCAGCACGGCCTGGTAGCCGACCCGGCGCTGCAGTTCGATGCGATCACCACCGAGTTGTCCGGTTACTCCGCG
TGCCTGGCCCTGCTGGACAGCGGCAATGCGTTCGATGCGGTCTGCGCAGCCAGCGATCTGATCGCGATCGGTGCGATGCG
CGCCCTGCGCGAGCGCGGCCTGCGAGTGCCGCAGGACGTGGCGGTCAGCGGCTTCGACGATATTGCGTTGGCGGCGTCGG
TTGCGCCGGCGTTGTCGACCGTGCAGCAGGACACCAAGCAGGCCGGCACACTGCTGGTGGAAAGTCTGGTTGCCTTGATT
CGCGGCGAAGCGGCGCAGAGCCGCACGATTCCGGTGCGCCTGGCGCTACGCGATTCCTCGCGCAGCAGCGGGCTGCAGCC
GCCACTGGGTTGGGCGCCGTCCGGCGCAGAGGCCGGCGATGCGATGACGGGTCGAGCGGCGGATGGGGCGGTCAGGGGCT
GA

Upstream 100 bases:

>100_bases
GGCATGAATGGTAAACCAATCAGACGCCCGCTGCGTACGGCGGCACGGCGCTGGCAGGCGCATGGCATGATGCCGGCCAC
CTGTCCTGCCGTTGCCAATC

Downstream 100 bases:

>100_bases
TTCGGGATCGGGACCCGGGACAGCGCGCCGGTTGGGTTGCGAGATCTCGCAACCCGCTGGGTGCGTCGTAGGAGCGCCCG
CGGGCGCGACGCGTTACCGG

Product: maltose transport gene repressor

Products: NA

Alternate protein names: Probable galacturonate locus repressor [H]

Number of amino acids: Translated: 373; Mature: 372

Protein sequence:

>373_residues
MTIKGKATSLDIAYLAGVSQPTVSRALRGSPMVNEETRKRILRIARELNYKVDKNASSLRLRNAGTLALLFFEDPTADDS
LINPFFHSMLGSITRACALQGYDLLVSFQQLSKDWQADYEDSNKADGIILLGYGDYQQSRQRLQLLVEQGTHFVRWGAAL
PGQPGISIGSDNYQGGLDITDHLLAQGCRRIAFLGHASNHYPEFEERYRGHATALAQHGLVADPALQFDAITTELSGYSA
CLALLDSGNAFDAVCAASDLIAIGAMRALRERGLRVPQDVAVSGFDDIALAASVAPALSTVQQDTKQAGTLLVESLVALI
RGEAAQSRTIPVRLALRDSSRSSGLQPPLGWAPSGAEAGDAMTGRAADGAVRG

Sequences:

>Translated_373_residues
MTIKGKATSLDIAYLAGVSQPTVSRALRGSPMVNEETRKRILRIARELNYKVDKNASSLRLRNAGTLALLFFEDPTADDS
LINPFFHSMLGSITRACALQGYDLLVSFQQLSKDWQADYEDSNKADGIILLGYGDYQQSRQRLQLLVEQGTHFVRWGAAL
PGQPGISIGSDNYQGGLDITDHLLAQGCRRIAFLGHASNHYPEFEERYRGHATALAQHGLVADPALQFDAITTELSGYSA
CLALLDSGNAFDAVCAASDLIAIGAMRALRERGLRVPQDVAVSGFDDIALAASVAPALSTVQQDTKQAGTLLVESLVALI
RGEAAQSRTIPVRLALRDSSRSSGLQPPLGWAPSGAEAGDAMTGRAADGAVRG
>Mature_372_residues
TIKGKATSLDIAYLAGVSQPTVSRALRGSPMVNEETRKRILRIARELNYKVDKNASSLRLRNAGTLALLFFEDPTADDSL
INPFFHSMLGSITRACALQGYDLLVSFQQLSKDWQADYEDSNKADGIILLGYGDYQQSRQRLQLLVEQGTHFVRWGAALP
GQPGISIGSDNYQGGLDITDHLLAQGCRRIAFLGHASNHYPEFEERYRGHATALAQHGLVADPALQFDAITTELSGYSAC
LALLDSGNAFDAVCAASDLIAIGAMRALRERGLRVPQDVAVSGFDDIALAASVAPALSTVQQDTKQAGTLLVESLVALIR
GEAAQSRTIPVRLALRDSSRSSGLQPPLGWAPSGAEAGDAMTGRAADGAVRG

Specific function: Transcriptional repressor for the exu locus which is required for galacturonate utilization (Probable) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789068, Length=337, Percent_Identity=29.9703264094956, Blast_Score=121, Evalue=6e-29,
Organism=Escherichia coli, GI1790194, Length=327, Percent_Identity=29.0519877675841, Blast_Score=116, Evalue=3e-27,
Organism=Escherichia coli, GI1790369, Length=344, Percent_Identity=28.1976744186047, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789202, Length=299, Percent_Identity=31.1036789297659, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787580, Length=339, Percent_Identity=27.4336283185841, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1790715, Length=324, Percent_Identity=25.9259259259259, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789456, Length=350, Percent_Identity=28.2857142857143, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1787948, Length=349, Percent_Identity=26.647564469914, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI48994940, Length=334, Percent_Identity=24.251497005988, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788474, Length=313, Percent_Identity=27.7955271565495, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI1786540, Length=345, Percent_Identity=27.2463768115942, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1787906, Length=381, Percent_Identity=24.9343832020997, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 39898; Mature: 39767

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIKGKATSLDIAYLAGVSQPTVSRALRGSPMVNEETRKRILRIARELNYKVDKNASSLR
CCCCCCCCEEEHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEE
LRNAGTLALLFFEDPTADDSLINPFFHSMLGSITRACALQGYDLLVSFQQLSKDWQADYE
EECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
DSNKADGIILLGYGDYQQSRQRLQLLVEQGTHFVRWGAALPGQPGISIGSDNYQGGLDIT
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHH
DHLLAQGCRRIAFLGHASNHYPEFEERYRGHATALAQHGLVADPALQFDAITTELSGYSA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
CLALLDSGNAFDAVCAASDLIAIGAMRALRERGLRVPQDVAVSGFDDIALAASVAPALST
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
VQQDTKQAGTLLVESLVALIRGEAAQSRTIPVRLALRDSSRSSGLQPPLGWAPSGAEAGD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
AMTGRAADGAVRG
CCCCCCCCCCCCC
>Mature Secondary Structure 
TIKGKATSLDIAYLAGVSQPTVSRALRGSPMVNEETRKRILRIARELNYKVDKNASSLR
CCCCCCCEEEHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCEE
LRNAGTLALLFFEDPTADDSLINPFFHSMLGSITRACALQGYDLLVSFQQLSKDWQADYE
EECCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCC
DSNKADGIILLGYGDYQQSRQRLQLLVEQGTHFVRWGAALPGQPGISIGSDNYQGGLDIT
CCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCHH
DHLLAQGCRRIAFLGHASNHYPEFEERYRGHATALAQHGLVADPALQFDAITTELSGYSA
HHHHHHHHHHHHHCCCCCCCCCCHHHHHCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHH
CLALLDSGNAFDAVCAASDLIAIGAMRALRERGLRVPQDVAVSGFDDIALAASVAPALST
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHH
VQQDTKQAGTLLVESLVALIRGEAAQSRTIPVRLALRDSSRSSGLQPPLGWAPSGAEAGD
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCCCCC
AMTGRAADGAVRG
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9579062; 9384377 [H]