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The map label for this gene is dapA [H]

Identifier: 21243280

GI number: 21243280

Start: 3004721

End: 3005629

Strand: Reverse

Name: dapA [H]

Synonym: XAC2547

Alternate gene names: 21243280

Gene position: 3005629-3004721 (Counterclockwise)

Preceding gene: 21243281

Following gene: 21243279

Centisome position: 58.07

GC content: 66.34

Gene sequence:

>909_bases
ATGAGCAATGCTGCGTTCTGGCACGGCGTGCTGCCGGCCATCACCACTCCGTTCACCGCTAACGGCGACATCGACCACGA
CTTCCTCGGCAAGCACGCCAATCAACTGGTGGATGCCGGTTGCACCGCGATCGTGCCGCTGGGCTCGTTGGGCGAAGCTG
CGACCTTGAGCGTGGAAGACAAGCTGGCGATCCTGCGCACGCTGGTCACCGCCTTGAACGGTCGCGTGCCGGTGGTGCCG
GGCATCGCGAGCCTGGCCACCGGCGAAGCGGTCGCGCTGGCCAAGGCGGCCAAGGACATCGGCTGCGGCGGCTTGATGGT
GCTGCCGCCGTACGTGTACTCCACCGATTGGCGCGAAATGGGCGCGCATGTGCGCGCGGTGATCGGCGCAACCGATCTGC
CGGTGATCCTGTACAACAACCCGGTCGCCTACAAGACCGATTTCGGCCCGGCGCAGATCGCCGAGCTGGCCGCCGAATTC
CCGAACCTGCAGGCAGTGAAGGAATCGTCCGGCGACGTGCGCCGCTTCGCCGCACTGCAGGAATTGCTGGGCGATCGCCT
GGCGCTGCTGGTGGGCATGGACGATGCCATCGTCGAAGGCCTGAGCATGGGCGCCAAGGGTTGGATCGCCGGCCTGGTCA
ATGCGTATCCGAAGGAATCGGTGCGCCTGTTCGAACTCGCCCGCGATGGCGGTTACCCGGCGGCCAGGGAGCTTTACCAC
TGGTTCCTGCCGCTGCTGCGCCTGGATACGGTGCCCACCTTCGTGCAGCTGATCAAACTGGTGCAGGCCAAGGTCGGCAT
GGGCAGCGAGCAGGTGCGTGCGCCGCGCCTGGTGGTGGCCGGTGCCGAGCGCGATGCCGCGTTGAAGGTCATCGACCATG
CCATCGCCACCGCGCCCAAGTTGTCTTGA

Upstream 100 bases:

>100_bases
CCGATCTTTCCACCGACGCCGGCCGCCGGCCGCCGTTGTTCCCGGTCCGCCTCGCGGCGCTGGCCGACTCGTTCACTTCC
GACTCGCAAGGGAAACACCC

Downstream 100 bases:

>100_bases
TGGCGCCATGATGCTGCCATCGTCTGTTGCGCCTGCGGGTGAGCGCAGGGTGCGAGTCGTGCGGGTTCGTGCCACGCGCC
TTGCCTGCGCGCGGGGCGAT

Product: dihydrodipicolinate synthetase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MSNAAFWHGVLPAITTPFTANGDIDHDFLGKHANQLVDAGCTAIVPLGSLGEAATLSVEDKLAILRTLVTALNGRVPVVP
GIASLATGEAVALAKAAKDIGCGGLMVLPPYVYSTDWREMGAHVRAVIGATDLPVILYNNPVAYKTDFGPAQIAELAAEF
PNLQAVKESSGDVRRFAALQELLGDRLALLVGMDDAIVEGLSMGAKGWIAGLVNAYPKESVRLFELARDGGYPAARELYH
WFLPLLRLDTVPTFVQLIKLVQAKVGMGSEQVRAPRLVVAGAERDAALKVIDHAIATAPKLS

Sequences:

>Translated_302_residues
MSNAAFWHGVLPAITTPFTANGDIDHDFLGKHANQLVDAGCTAIVPLGSLGEAATLSVEDKLAILRTLVTALNGRVPVVP
GIASLATGEAVALAKAAKDIGCGGLMVLPPYVYSTDWREMGAHVRAVIGATDLPVILYNNPVAYKTDFGPAQIAELAAEF
PNLQAVKESSGDVRRFAALQELLGDRLALLVGMDDAIVEGLSMGAKGWIAGLVNAYPKESVRLFELARDGGYPAARELYH
WFLPLLRLDTVPTFVQLIKLVQAKVGMGSEQVRAPRLVVAGAERDAALKVIDHAIATAPKLS
>Mature_301_residues
SNAAFWHGVLPAITTPFTANGDIDHDFLGKHANQLVDAGCTAIVPLGSLGEAATLSVEDKLAILRTLVTALNGRVPVVPG
IASLATGEAVALAKAAKDIGCGGLMVLPPYVYSTDWREMGAHVRAVIGATDLPVILYNNPVAYKTDFGPAQIAELAAEFP
NLQAVKESSGDVRRFAALQELLGDRLALLVGMDDAIVEGLSMGAKGWIAGLVNAYPKESVRLFELARDGGYPAARELYHW
FLPLLRLDTVPTFVQLIKLVQAKVGMGSEQVRAPRLVVAGAERDAALKVIDHAIATAPKLS

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI13540533, Length=280, Percent_Identity=23.9285714285714, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI31543060, Length=235, Percent_Identity=24.2553191489362, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1788823, Length=291, Percent_Identity=27.8350515463918, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI87082415, Length=289, Percent_Identity=27.681660899654, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786463, Length=263, Percent_Identity=28.5171102661597, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1789620, Length=212, Percent_Identity=27.8301886792453, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31938; Mature: 31807

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNAAFWHGVLPAITTPFTANGDIDHDFLGKHANQLVDAGCTAIVPLGSLGEAATLSVED
CCCCCHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEECHHH
KLAILRTLVTALNGRVPVVPGIASLATGEAVALAKAAKDIGCGGLMVLPPYVYSTDWREM
HHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHH
GAHVRAVIGATDLPVILYNNPVAYKTDFGPAQIAELAAEFPNLQAVKESSGDVRRFAALQ
HHHHHHHHCCCCCCEEEECCCEEEECCCCHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHH
ELLGDRLALLVGMDDAIVEGLSMGAKGWIAGLVNAYPKESVRLFELARDGGYPAARELYH
HHHHHHHEEEECCCHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHH
WFLPLLRLDTVPTFVQLIKLVQAKVGMGSEQVRAPRLVVAGAERDAALKVIDHAIATAPK
HHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCC
LS
CC
>Mature Secondary Structure 
SNAAFWHGVLPAITTPFTANGDIDHDFLGKHANQLVDAGCTAIVPLGSLGEAATLSVED
CCCCHHHCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEECCCCCCCEEECHHH
KLAILRTLVTALNGRVPVVPGIASLATGEAVALAKAAKDIGCGGLMVLPPYVYSTDWREM
HHHHHHHHHHHHCCCCCCCCCHHHHHCCHHHHHHHHHHHCCCCCEEECCCCCCCCCHHHH
GAHVRAVIGATDLPVILYNNPVAYKTDFGPAQIAELAAEFPNLQAVKESSGDVRRFAALQ
HHHHHHHHCCCCCCEEEECCCEEEECCCCHHHHHHHHHHCCCHHHHHHCCCHHHHHHHHH
ELLGDRLALLVGMDDAIVEGLSMGAKGWIAGLVNAYPKESVRLFELARDGGYPAARELYH
HHHHHHHEEEECCCHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHHH
WFLPLLRLDTVPTFVQLIKLVQAKVGMGSEQVRAPRLVVAGAERDAALKVIDHAIATAPK
HHHHHHHHCCHHHHHHHHHHHHHHHCCCHHHHCCCEEEEECCCCHHHHHHHHHHHHCCCC
LS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA