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The map label for this gene is aldH [H]

Identifier: 21243279

GI number: 21243279

Start: 3002894

End: 3004510

Strand: Reverse

Name: aldH [H]

Synonym: XAC2546

Alternate gene names: 21243279

Gene position: 3004510-3002894 (Counterclockwise)

Preceding gene: 21243280

Following gene: 21243278

Centisome position: 58.05

GC content: 68.95

Gene sequence:

>1617_bases
ATGAACGATACGAACCACTCCATTCCCGCGGCAGCAGCCGAGATCCTGCTGGCAGGCCGATGGCAAGCCAGCCGCGCCGC
CACCGGCAGCTTCCGTGCTGCCGACCCGGCCGCCGGCGAACCAATCGGGCCCTACTTTCCGGTCAGTGGCGCGGACGATG
TGGAAGCGGCCGTGGTTGCGGCGCAGGCAGTGGCGGCGGAGTTGGCGGCCGCACCGGTCGAGCGGATCGCGGCCTTTCTG
GAAGCCTATGCCGATGCGCTAGATGCCGATGCCGATACCCTGGTCGCGCTGGCGCATGCCGAGACGGCGTTACCGGCGCC
CACACGCTTGCGCGGTAACGAACTGCCGCGCACCAGCGGCCAACTGCGGCAGGCCGCACGGGCCGTGCGCAGCTACAGCT
GGACCCAGCCCATCATCGACAGCGCGGCAGATCTGCGTTCGCACCTGGCGCCGCTGGGCAAACCGGTGCTGGTATTCGGC
CCGAACAACTTTCCGTTCGCGTTCAATGCAATTGCCGGCAGCGATTTCGCCTCGGCGATTGCCGCGCGCAACCCGGTCAT
CGCCAAGGCGCATCCGTTGCATCCGGCCACCAGCCAGCGCATGGCGCAGCTCGCGCATCAGGCCTTGCTCGCGGCCGGTC
TGCCTGCGGCGGCGGTGCAACTGCTGTATCACTTCGACAATGCCATCGGCCTGCGATTGGCGGGCGATGCGCGGCTGGGC
GCGATCGGATTCACTGGCAGCCGTGCCGGTGGGCTGGCCCTGAAGGCCGCCGCAGACGCGGCGGGCGTGCCGTTTTATGC
CGAGCTTTCCAGCGTCAACCCGGTCTTCCTGTTGCCGGGCGCGCTGGCCGAACGCGGCGATGCGCTTGCGCAGGAATTCT
TCGCCTCCTGCACGCTGGGTAGCGGGCAGTTCTGCACCAATCCCGGTGTGGTGGTGGTGCCGCATGGCGCGGCTGGCGAT
GCGTTCGTTGCGGCCAGCAAGGCGCATTTCGAAGCGGCCATGCCGATGGTGCTGTTCTCCGCCTCTGGTGTAGAAGGCGT
GCAACGCGGCGTGGCGAGCCTACGTGCGGCCGGCGCCGGCATGCTGGCCGGCGGGCACACCGGCGAGGATGGCTACCGCT
ATGCGCCGACCTTGTTGAGCGTGGATGCGCAAGCCTTCCTCGCCAATCCGCACGCCCTGCAGGCCGAAGCCTTCGGGCCT
GTGAGCCTGCTGGTGCGCGCAGCCGATGTGGCGCAGATGGCACAGGTGGCTGCTGCGTTCGAAGGCAATCTGACCGGCAC
GTTGTACCGCGCGGCCGACGGCCGCGACGATGCCGCGTGGCAGACCATCGCCCCGGTGCTGCGTGCGCGGGTAGGGCGCT
TGATCAACAGCAAGATGCCAACCGGCGTGGCCGTGAGCGCTGCGCAAAACCACGGTGGCCCGTTCCCGAGCACCGGGCAT
CCGGGCTTCACGGCGGTGGGCATGCCCGGCGCCATCCGCCGTTTTGCCGCCTTGCACAGTTACGACGCGGTGCCCGATGC
ACTGCTGCCCGCCGAACTGCGCCAGCGCAATCCGGGCGGCGTGGCACGTCTGGTCGACGGGCAATGGAGCACGGCCGATC
TTGGAGCCGGCGCATGA

Upstream 100 bases:

>100_bases
ATGCGGATGTGGCATCCAGTGCCGCATCCTCATCGTCTTTCTGGTCGGCCGCCAGCGCACCGAGCGCCGGACCTGCCTCC
CTGTCACCGAAGGTGCCGCA

Downstream 100 bases:

>100_bases
AGCGACAGATCGGCGGGCTGTCGCTGGAGCAAGCGCGTGCGCAACTCGCGCCGTGGACACAACGCGCCGCGCCGATCGCC
GCGGACGAATACGAGCGCCG

Product: ketoglutarate semialdehyde dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MNDTNHSIPAAAAEILLAGRWQASRAATGSFRAADPAAGEPIGPYFPVSGADDVEAAVVAAQAVAAELAAAPVERIAAFL
EAYADALDADADTLVALAHAETALPAPTRLRGNELPRTSGQLRQAARAVRSYSWTQPIIDSAADLRSHLAPLGKPVLVFG
PNNFPFAFNAIAGSDFASAIAARNPVIAKAHPLHPATSQRMAQLAHQALLAAGLPAAAVQLLYHFDNAIGLRLAGDARLG
AIGFTGSRAGGLALKAAADAAGVPFYAELSSVNPVFLLPGALAERGDALAQEFFASCTLGSGQFCTNPGVVVVPHGAAGD
AFVAASKAHFEAAMPMVLFSASGVEGVQRGVASLRAAGAGMLAGGHTGEDGYRYAPTLLSVDAQAFLANPHALQAEAFGP
VSLLVRAADVAQMAQVAAAFEGNLTGTLYRAADGRDDAAWQTIAPVLRARVGRLINSKMPTGVAVSAAQNHGGPFPSTGH
PGFTAVGMPGAIRRFAALHSYDAVPDALLPAELRQRNPGGVARLVDGQWSTADLGAGA

Sequences:

>Translated_538_residues
MNDTNHSIPAAAAEILLAGRWQASRAATGSFRAADPAAGEPIGPYFPVSGADDVEAAVVAAQAVAAELAAAPVERIAAFL
EAYADALDADADTLVALAHAETALPAPTRLRGNELPRTSGQLRQAARAVRSYSWTQPIIDSAADLRSHLAPLGKPVLVFG
PNNFPFAFNAIAGSDFASAIAARNPVIAKAHPLHPATSQRMAQLAHQALLAAGLPAAAVQLLYHFDNAIGLRLAGDARLG
AIGFTGSRAGGLALKAAADAAGVPFYAELSSVNPVFLLPGALAERGDALAQEFFASCTLGSGQFCTNPGVVVVPHGAAGD
AFVAASKAHFEAAMPMVLFSASGVEGVQRGVASLRAAGAGMLAGGHTGEDGYRYAPTLLSVDAQAFLANPHALQAEAFGP
VSLLVRAADVAQMAQVAAAFEGNLTGTLYRAADGRDDAAWQTIAPVLRARVGRLINSKMPTGVAVSAAQNHGGPFPSTGH
PGFTAVGMPGAIRRFAALHSYDAVPDALLPAELRQRNPGGVARLVDGQWSTADLGAGA
>Mature_538_residues
MNDTNHSIPAAAAEILLAGRWQASRAATGSFRAADPAAGEPIGPYFPVSGADDVEAAVVAAQAVAAELAAAPVERIAAFL
EAYADALDADADTLVALAHAETALPAPTRLRGNELPRTSGQLRQAARAVRSYSWTQPIIDSAADLRSHLAPLGKPVLVFG
PNNFPFAFNAIAGSDFASAIAARNPVIAKAHPLHPATSQRMAQLAHQALLAAGLPAAAVQLLYHFDNAIGLRLAGDARLG
AIGFTGSRAGGLALKAAADAAGVPFYAELSSVNPVFLLPGALAERGDALAQEFFASCTLGSGQFCTNPGVVVVPHGAAGD
AFVAASKAHFEAAMPMVLFSASGVEGVQRGVASLRAAGAGMLAGGHTGEDGYRYAPTLLSVDAQAFLANPHALQAEAFGP
VSLLVRAADVAQMAQVAAAFEGNLTGTLYRAADGRDDAAWQTIAPVLRARVGRLINSKMPTGVAVSAAQNHGGPFPSTGH
PGFTAVGMPGAIRRFAALHSYDAVPDALLPAELRQRNPGGVARLVDGQWSTADLGAGA

Specific function: Catalyzes the oxidation of long-chain aliphatic aldehydes to acids. May be implicated in controlling luminescence as it catalyzes the oxidation of the fatty aldehyde substrate for the light-emitting reaction [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787250, Length=280, Percent_Identity=29.6428571428571, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1787558, Length=425, Percent_Identity=26.5882352941176, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016162
- InterPro:   IPR015590 [H]

Pfam domain/function: PF00171 Aldedh [H]

EC number: =1.2.1.4 [H]

Molecular weight: Translated: 54757; Mature: 54757

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDTNHSIPAAAAEILLAGRWQASRAATGSFRAADPAAGEPIGPYFPVSGADDVEAAVVA
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AQAVAAELAAAPVERIAAFLEAYADALDADADTLVALAHAETALPAPTRLRGNELPRTSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEHHHHHCCCCCCCCCCCCCCCCHH
QLRQAARAVRSYSWTQPIIDSAADLRSHLAPLGKPVLVFGPNNFPFAFNAIAGSDFASAI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCHHHHHH
AARNPVIAKAHPLHPATSQRMAQLAHQALLAAGLPAAAVQLLYHFDNAIGLRLAGDARLG
HHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCEE
AIGFTGSRAGGLALKAAADAAGVPFYAELSSVNPVFLLPGALAERGDALAQEFFASCTLG
EEECCCCCCCCEEEEECCCCCCCCEEEHHCCCCCEEEECCHHHHHHHHHHHHHHHHHCCC
SGQFCTNPGVVVVPHGAAGDAFVAASKAHFEAAMPMVLFSASGVEGVQRGVASLRAAGAG
CCCEECCCCEEEEECCCCCCHHEEECHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCC
MLAGGHTGEDGYRYAPTLLSVDAQAFLANPHALQAEAFGPVSLLVRAADVAQMAQVAAAF
EEECCCCCCCCCEECCHHEECCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EGNLTGTLYRAADGRDDAAWQTIAPVLRARVGRLINSKMPTGVAVSAAQNHGGPFPSTGH
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCC
PGFTAVGMPGAIRRFAALHSYDAVPDALLPAELRQRNPGGVARLVDGQWSTADLGAGA
CCEEEECCCHHHHHHHHHHHCCCCCCHHCCHHHHCCCCCCEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MNDTNHSIPAAAAEILLAGRWQASRAATGSFRAADPAAGEPIGPYFPVSGADDVEAAVVA
CCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
AQAVAAELAAAPVERIAAFLEAYADALDADADTLVALAHAETALPAPTRLRGNELPRTSG
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHEEEHHHHHCCCCCCCCCCCCCCCCHH
QLRQAARAVRSYSWTQPIIDSAADLRSHLAPLGKPVLVFGPNNFPFAFNAIAGSDFASAI
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEECCCCHHHHHH
AARNPVIAKAHPLHPATSQRMAQLAHQALLAAGLPAAAVQLLYHFDNAIGLRLAGDARLG
HHCCCCEECCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCEE
AIGFTGSRAGGLALKAAADAAGVPFYAELSSVNPVFLLPGALAERGDALAQEFFASCTLG
EEECCCCCCCCEEEEECCCCCCCCEEEHHCCCCCEEEECCHHHHHHHHHHHHHHHHHCCC
SGQFCTNPGVVVVPHGAAGDAFVAASKAHFEAAMPMVLFSASGVEGVQRGVASLRAAGAG
CCCEECCCCEEEEECCCCCCHHEEECHHHHHHHCCCCEEECCCHHHHHHHHHHHHHCCCC
MLAGGHTGEDGYRYAPTLLSVDAQAFLANPHALQAEAFGPVSLLVRAADVAQMAQVAAAF
EEECCCCCCCCCEECCHHEECCHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
EGNLTGTLYRAADGRDDAAWQTIAPVLRARVGRLINSKMPTGVAVSAAQNHGGPFPSTGH
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHHCCCCCCCCCC
PGFTAVGMPGAIRRFAALHSYDAVPDALLPAELRQRNPGGVARLVDGQWSTADLGAGA
CCEEEECCCHHHHHHHHHHHCCCCCCHHCCHHHHCCCCCCEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8527447; 10903148 [H]