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The map label for this gene is fruK [H]

Identifier: 21243235

GI number: 21243235

Start: 2926886

End: 2927842

Strand: Direct

Name: fruK [H]

Synonym: XAC2502

Alternate gene names: 21243235

Gene position: 2926886-2927842 (Clockwise)

Preceding gene: 21243234

Following gene: 21243236

Centisome position: 56.55

GC content: 70.85

Gene sequence:

>957_bases
ATGAGCCTGCAGGCCATCACCGTCACGCTGAACCCGGCGATCGACCAGACCATCCAGCTCGAACACCTGCAGCCTGGCGC
CGTGCACCGCGCCAGCAGCGTGCGCAACGATGCCGGCGGCAAGGGCATCAATGTGGCCGCGTGCCTGGCCGACTGGGGCA
GCGAGGTTGCTGCGCTGGGCGCGCTCGGGGTCGGCAATGCCGGCGTATTCGAAGCCCTGTTCCGCGAACGCGGCATCGCC
GATCACTGCCAGCGCGTGGCCGGCGAAACCCGTACCAATCTCAAGTTGGTCGACGCGCGCAGCAACGACACCACCGACAT
CAACCTGCCCGGCCTGCGCTTAGGGCCTGCGCATCTGCAAGGCGTGGCCGATCATCTCGCCCCGCTGCTGCGCCCCGGCC
TGCCGGTGGTGCTGTCGGGCAGCCTGCCGGCCGGGCTGCCGGACGACAGCTGGGCGCAATTGCAGGCCCAGGCCAGCGCT
GCCGGTGCGCGCGTGCTGCTGGACACCAGCGGCATGCCGCTGGTGAGCGCGCTGGATGCCGCGCGCGAGGCGCTGCCGTA
TGCGGTCAAGCCCAATCGCGACGAACTCGCGGCCTGGACCGGCCGCCCGTTGAACGACCGCGGCGCACTCAGCGCCGCCG
CGCACGAACTGATCGCACGCGGCATCCAGCTGGTGGTCATTTCGATGGGCACCGAAGGCGCCCTGTTCGTGCAGCGCGAC
CAGCGGTTGATTGCCCGCCCGCCACGCCTGGCGCACGGCAGCAGCGTGGGCGCAGGCGATGCGATGGTGGCCGGTCTGGC
CGCCGCCTCGCTCGATGCCGCGACCACGCTGGAGCAGTGCGCACGGCTGGCCACGGCGTTTTCGATGTGCCGGCTGGAAA
GCGGCGACGCGCGCCGGATGACCCCAGAGGGCGTGCGCCGCGCCGCAACCGACGTCGTGATCGAAATGCTGTCATGA

Upstream 100 bases:

>100_bases
GCGCCGCGTTGAGCCAGCTGCAACAGCTCGCCGAACAAGCGCTGGCCTGCGAAACCGCCGAACAGGTGCGCGCATTGGAA
GCCAAGCGCGAGGACAAGGC

Downstream 100 bases:

>100_bases
GCCGCCATTGGCCACTGCCGATGCATGCACCCAGGTGGCCGTCGGGCCGGCAGTTGCAGACAGCGGCAGATCGCGCGCAT
CACCGCCACGCATAACGCTT

Product: 1-phosphofructokinase

Products: NA

Alternate protein names: Fructose 1-phosphate kinase [H]

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSLQAITVTLNPAIDQTIQLEHLQPGAVHRASSVRNDAGGKGINVAACLADWGSEVAALGALGVGNAGVFEALFRERGIA
DHCQRVAGETRTNLKLVDARSNDTTDINLPGLRLGPAHLQGVADHLAPLLRPGLPVVLSGSLPAGLPDDSWAQLQAQASA
AGARVLLDTSGMPLVSALDAAREALPYAVKPNRDELAAWTGRPLNDRGALSAAAHELIARGIQLVVISMGTEGALFVQRD
QRLIARPPRLAHGSSVGAGDAMVAGLAAASLDAATTLEQCARLATAFSMCRLESGDARRMTPEGVRRAATDVVIEMLS

Sequences:

>Translated_318_residues
MSLQAITVTLNPAIDQTIQLEHLQPGAVHRASSVRNDAGGKGINVAACLADWGSEVAALGALGVGNAGVFEALFRERGIA
DHCQRVAGETRTNLKLVDARSNDTTDINLPGLRLGPAHLQGVADHLAPLLRPGLPVVLSGSLPAGLPDDSWAQLQAQASA
AGARVLLDTSGMPLVSALDAAREALPYAVKPNRDELAAWTGRPLNDRGALSAAAHELIARGIQLVVISMGTEGALFVQRD
QRLIARPPRLAHGSSVGAGDAMVAGLAAASLDAATTLEQCARLATAFSMCRLESGDARRMTPEGVRRAATDVVIEMLS
>Mature_317_residues
SLQAITVTLNPAIDQTIQLEHLQPGAVHRASSVRNDAGGKGINVAACLADWGSEVAALGALGVGNAGVFEALFRERGIAD
HCQRVAGETRTNLKLVDARSNDTTDINLPGLRLGPAHLQGVADHLAPLLRPGLPVVLSGSLPAGLPDDSWAQLQAQASAA
GARVLLDTSGMPLVSALDAAREALPYAVKPNRDELAAWTGRPLNDRGALSAAAHELIARGIQLVVISMGTEGALFVQRDQ
RLIARPPRLAHGSSVGAGDAMVAGLAAASLDAATTLEQCARLATAFSMCRLESGDARRMTPEGVRRAATDVVIEMLS

Specific function: Unknown

COG id: COG1105

COG function: function code G; Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the carbohydrate kinase pfkB family [H]

Homologues:

Organism=Escherichia coli, GI1788493, Length=267, Percent_Identity=40.4494382022472, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1788017, Length=281, Percent_Identity=29.8932384341637, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022463
- InterPro:   IPR011611
- InterPro:   IPR002173
- InterPro:   IPR017583 [H]

Pfam domain/function: PF00294 PfkB [H]

EC number: =2.7.1.56 [H]

Molecular weight: Translated: 32977; Mature: 32846

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00583 PFKB_KINASES_1 ; PS00584 PFKB_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLQAITVTLNPAIDQTIQLEHLQPGAVHRASSVRNDAGGKGINVAACLADWGSEVAALG
CCCEEEEEEECCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
ALGVGNAGVFEALFRERGIADHCQRVAGETRTNLKLVDARSNDTTDINLPGLRLGPAHLQ
HCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCCEECHHHHH
GVADHLAPLLRPGLPVVLSGSLPAGLPDDSWAQLQAQASAAGARVLLDTSGMPLVSALDA
HHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
AREALPYAVKPNRDELAAWTGRPLNDRGALSAAAHELIARGIQLVVISMGTEGALFVQRD
HHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCEEEEECC
QRLIARPPRLAHGSSVGAGDAMVAGLAAASLDAATTLEQCARLATAFSMCRLESGDARRM
CHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TPEGVRRAATDVVIEMLS
CHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLQAITVTLNPAIDQTIQLEHLQPGAVHRASSVRNDAGGKGINVAACLADWGSEVAALG
CCEEEEEEECCCCCCEEEEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
ALGVGNAGVFEALFRERGIADHCQRVAGETRTNLKLVDARSNDTTDINLPGLRLGPAHLQ
HCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEECCCCCCCEECCCCCEECHHHHH
GVADHLAPLLRPGLPVVLSGSLPAGLPDDSWAQLQAQASAAGARVLLDTSGMPLVSALDA
HHHHHHHHHHCCCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHH
AREALPYAVKPNRDELAAWTGRPLNDRGALSAAAHELIARGIQLVVISMGTEGALFVQRD
HHHHCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCEEEEEEEECCCCEEEEECC
QRLIARPPRLAHGSSVGAGDAMVAGLAAASLDAATTLEQCARLATAFSMCRLESGDARRM
CHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
TPEGVRRAATDVVIEMLS
CHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655739; 12024217 [H]