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The map label for this gene is rrpX [H]

Identifier: 21243215

GI number: 21243215

Start: 2890564

End: 2891808

Strand: Direct

Name: rrpX [H]

Synonym: XAC2482

Alternate gene names: 21243215

Gene position: 2890564-2891808 (Clockwise)

Preceding gene: 21243214

Following gene: 21243216

Centisome position: 55.85

GC content: 63.45

Gene sequence:

>1245_bases
GTGCTGTTGGTGGAGAACTCGCGCACGTTCACCAGCATGCTGCGCGAAGCCATCGAGCAACGCGTGGAACTCCCGGTCAC
GGTCGTCTCGACCCTGGCCGAAGCGGCGCGTGTATTGGACGAAGAGGACGGCTGGTTTCTGGTCCTCACCGGCCTGGTGC
TGGTCGATGGCGACCGCGACAAGGTCGTGGAATTCTTTCTCTCGCGCAAACTGCCCACCGTGGTGGTCAGCGGCGTGTAC
GACGAAGACCTGCGCCAGCGCGTGCTGCAGCAGCAGATCATCGATTACGTGCTGAAAAATGCACCGGGCAGCATCGAGTA
CCTGGCATGGCTGGTGCAGCGCCTGGAGCGCAATCGCCGGATCGCCGCCCTGGTGGTGGACGATTCGCTGTCGGCACGCA
CCTATGCCGGCGCCCTGCTGTCGATGTACGGCTACCGCGTGGTGCTGGCGGCCGACGGCGCTGCCGGGCTGGACGCGATC
GAACGCGACCCCGACATTCGCCTGACCATCGTCGACCAGGAAATGCCTGGAATGGATGGCGTGGAATTCACCCGCCGGCT
GCGCGCGATCCGCTCGCGCGACAAGGTGGCGGTGATCGGCATATCCGGCAACAGCGATTCGTCGCTGATCCCGCGTTTCC
TGAAGAACGGCGCCAACGACTTCCTGCGCAAACCCTTTTCGCGCGAAGAATTCTTCTGCCGCGTGTCGCAGAACGTGGAC
CAGTTGGAACTGATCGGCACGCTGCAGGATCTTGCCACCCGCGACTTCCTCACCGGCCTGCCCAACCGGCGCTATTTTCT
GGAACAGAGCCAACGGGTCATTCCAAAGCTGTTGTTGGAGGACCAGACGGTGACCGCCGCGATGGTGGATATCGACCATT
TCAAGCACATCAACGACACCTGGGGCCATGAAGCCGGCGACCAAGCGTTGCGTGCGGTGGCCGCGTCGGTGTCCGGGCAT
GCGCGGCCGCAAGATCTGGTCGCACGCTTCGGTGGCGAAGAATTCTGCCTGTTGGTGCCCGGGCTGGATGCCGCCAACGC
CACCAGCTATTTCGAAACCCTGCGCGAGCGCATCAGCGCCCTGCGCGTGCGCGTGGGAGACGAGACGTTGAGCATGACGG
TGAGCATCGGCGTATGCATCGCCAGCGAAAGCGACCAGTCGCTGCATTACCTGCTGAACGAAGCGGACAAGCACCTGTAT
CTGGCCAAGGCCGGCGGCCGTAACCAGGTGCGTCTGGCAAGCTGA

Upstream 100 bases:

>100_bases
GCAGGGCCGTTAGCTGACCTGACGGTTCGATCCAGACGGCCAGCCGATGTCCCCAGGTACCCTACATCGCAATAGTGAAA
GTGCAGTCCTACCGCAGCGG

Downstream 100 bases:

>100_bases
TCCCGCATCGTCTGCAGGCCCAAGCGGCGCGTGCGGATGACGCGCCTGCCGACATGCCTTGATCCAGATCAACGCCCGGC
CGGCGCGCGTGGCTTACCGT

Product: transcriptional regulator

Products: NA

Alternate protein names: Stalked cell differentiation-controlling protein; Diguanylate cyclase; DGC; Diguanylate kinase [H]

Number of amino acids: Translated: 414; Mature: 414

Protein sequence:

>414_residues
MLLVENSRTFTSMLREAIEQRVELPVTVVSTLAEAARVLDEEDGWFLVLTGLVLVDGDRDKVVEFFLSRKLPTVVVSGVY
DEDLRQRVLQQQIIDYVLKNAPGSIEYLAWLVQRLERNRRIAALVVDDSLSARTYAGALLSMYGYRVVLAADGAAGLDAI
ERDPDIRLTIVDQEMPGMDGVEFTRRLRAIRSRDKVAVIGISGNSDSSLIPRFLKNGANDFLRKPFSREEFFCRVSQNVD
QLELIGTLQDLATRDFLTGLPNRRYFLEQSQRVIPKLLLEDQTVTAAMVDIDHFKHINDTWGHEAGDQALRAVAASVSGH
ARPQDLVARFGGEEFCLLVPGLDAANATSYFETLRERISALRVRVGDETLSMTVSIGVCIASESDQSLHYLLNEADKHLY
LAKAGGRNQVRLAS

Sequences:

>Translated_414_residues
MLLVENSRTFTSMLREAIEQRVELPVTVVSTLAEAARVLDEEDGWFLVLTGLVLVDGDRDKVVEFFLSRKLPTVVVSGVY
DEDLRQRVLQQQIIDYVLKNAPGSIEYLAWLVQRLERNRRIAALVVDDSLSARTYAGALLSMYGYRVVLAADGAAGLDAI
ERDPDIRLTIVDQEMPGMDGVEFTRRLRAIRSRDKVAVIGISGNSDSSLIPRFLKNGANDFLRKPFSREEFFCRVSQNVD
QLELIGTLQDLATRDFLTGLPNRRYFLEQSQRVIPKLLLEDQTVTAAMVDIDHFKHINDTWGHEAGDQALRAVAASVSGH
ARPQDLVARFGGEEFCLLVPGLDAANATSYFETLRERISALRVRVGDETLSMTVSIGVCIASESDQSLHYLLNEADKHLY
LAKAGGRNQVRLAS
>Mature_414_residues
MLLVENSRTFTSMLREAIEQRVELPVTVVSTLAEAARVLDEEDGWFLVLTGLVLVDGDRDKVVEFFLSRKLPTVVVSGVY
DEDLRQRVLQQQIIDYVLKNAPGSIEYLAWLVQRLERNRRIAALVVDDSLSARTYAGALLSMYGYRVVLAADGAAGLDAI
ERDPDIRLTIVDQEMPGMDGVEFTRRLRAIRSRDKVAVIGISGNSDSSLIPRFLKNGANDFLRKPFSREEFFCRVSQNVD
QLELIGTLQDLATRDFLTGLPNRRYFLEQSQRVIPKLLLEDQTVTAAMVDIDHFKHINDTWGHEAGDQALRAVAASVSGH
ARPQDLVARFGGEEFCLLVPGLDAANATSYFETLRERISALRVRVGDETLSMTVSIGVCIASESDQSLHYLLNEADKHLY
LAKAGGRNQVRLAS

Specific function: Catalyzes the condensation of two GTP molecules to the cyclic dinucleotide di-GMP (c-di-GMP), which acts as a secondary messenger [H]

COG id: COG3706

COG function: function code T; Response regulator containing a CheY-like receiver domain and a GGDEF domain

Gene ontology:

Cell location: Cytoplasm. Note=Phosphorylated PleD localizes to the differentiating pole [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 response regulatory domains [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=169, Percent_Identity=36.094674556213, Blast_Score=107, Evalue=1e-24,
Organism=Escherichia coli, GI1787262, Length=167, Percent_Identity=35.9281437125749, Blast_Score=105, Evalue=6e-24,
Organism=Escherichia coli, GI87082007, Length=169, Percent_Identity=36.094674556213, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI87081881, Length=180, Percent_Identity=38.8888888888889, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1788085, Length=165, Percent_Identity=35.1515151515151, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI145693134, Length=192, Percent_Identity=30.7291666666667, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1787802, Length=203, Percent_Identity=32.0197044334975, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI1787541, Length=197, Percent_Identity=30.4568527918782, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788381, Length=159, Percent_Identity=28.9308176100629, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=30.188679245283, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87081974, Length=151, Percent_Identity=29.8013245033113, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI87081977, Length=104, Percent_Identity=37.5, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR011006
- InterPro:   IPR000160
- InterPro:   IPR001789 [H]

Pfam domain/function: PF00990 GGDEF; PF00072 Response_reg [H]

EC number: =2.7.7.65 [H]

Molecular weight: Translated: 46185; Mature: 46185

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLVENSRTFTSMLREAIEQRVELPVTVVSTLAEAARVLDEEDGWFLVLTGLVLVDGDRD
CEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCHH
KVVEFFLSRKLPTVVVSGVYDEDLRQRVLQQQIIDYVLKNAPGSIEYLAWLVQRLERNRR
HHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
IAALVVDDSLSARTYAGALLSMYGYRVVLAADGAAGLDAIERDPDIRLTIVDQEMPGMDG
EEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHCCCCCEEEEEEECCCCCCCH
VEFTRRLRAIRSRDKVAVIGISGNSDSSLIPRFLKNGANDFLRKPFSREEFFCRVSQNVD
HHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCH
QLELIGTLQDLATRDFLTGLPNRRYFLEQSQRVIPKLLLEDQTVTAAMVDIDHFKHINDT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHH
WGHEAGDQALRAVAASVSGHARPQDLVARFGGEEFCLLVPGLDAANATSYFETLRERISA
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
LRVRVGDETLSMTVSIGVCIASESDQSLHYLLNEADKHLYLAKAGGRNQVRLAS
HHHEECCCCEEEEEEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCEEECC
>Mature Secondary Structure
MLLVENSRTFTSMLREAIEQRVELPVTVVSTLAEAARVLDEEDGWFLVLTGLVLVDGDRD
CEEECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCEEEEEEEEEEEECCHH
KVVEFFLSRKLPTVVVSGVYDEDLRQRVLQQQIIDYVLKNAPGSIEYLAWLVQRLERNRR
HHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCC
IAALVVDDSLSARTYAGALLSMYGYRVVLAADGAAGLDAIERDPDIRLTIVDQEMPGMDG
EEEEEEECCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHHCCCCCEEEEEEECCCCCCCH
VEFTRRLRAIRSRDKVAVIGISGNSDSSLIPRFLKNGANDFLRKPFSREEFFCRVSQNVD
HHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCH
QLELIGTLQDLATRDFLTGLPNRRYFLEQSQRVIPKLLLEDQTVTAAMVDIDHFKHINDT
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCHH
WGHEAGDQALRAVAASVSGHARPQDLVARFGGEEFCLLVPGLDAANATSYFETLRERISA
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHH
LRVRVGDETLSMTVSIGVCIASESDQSLHYLLNEADKHLYLAKAGGRNQVRLAS
HHHEECCCCEEEEEEEEEEEECCCCCHHHHHHHHCCCEEEEEECCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA