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The map label for this gene is glnA [H]

Identifier: 21243213

GI number: 21243213

Start: 2887730

End: 2889109

Strand: Direct

Name: glnA [H]

Synonym: XAC2480

Alternate gene names: 21243213

Gene position: 2887730-2889109 (Clockwise)

Preceding gene: 21243201

Following gene: 21243214

Centisome position: 55.8

GC content: 66.45

Gene sequence:

>1380_bases
ATGGCTTCCGAGACTTCCGTCGCGTCCCTGCCCGCTGCCGATGCCCACACCCTCTCTCGCATCGCCGGGTGCGAGTCTGT
CGATCTGTTATTGCCCGACACCAATGGCGTGCTGCGCGGCAAGCGCGTAACCGCCGATGCGCTGAGCAAGGTGTATCGCG
ACGGCGTGTGCCTGCCGATGTCGCTGATCGCCACCGACATCACCGGCAACACCGTGGAAGAAACCGGTCTTGGCTACGCG
ATCGGCGACGCCGACCGCATCTGCCGGCCGATCGAAGGCTCGCTACGACTGGTGCCCTGGGCGCCACGGCCGATGGCGCA
GCTGTTGCTGGCGATGCACACACCCGAAGGCGGGCTGTTCGAAGTCGCCCCGCGGGCGGTGTTGCAGCGCGTGCTGCAGG
GGTTTGGCGCACTCGGCCTGACCCCGGTCATCGCCGTAGAGCTTGAGTTCTATCTGTTCGATGCGGTGGCCGATGCGCAG
GGGCGCCCGCAAACCCCGCGCGACCCGATCACCGGCGAACGCAGCGACAGCACGCAGGTATATTCGCTGCAGGATCTGGA
CGACCAGCGTGGCTTCACCGATGCGGTCACCGTCGCTTGCAGACAGCAAGGCATTCCGGCCGACACCGCCGTGGCCGAGT
ACGCACCCGGCCAGTTCGAAATCAATCTGCAACACCGTGCCGATGCGGTGGCCGCCTGCGACGAGGCGGTTCTGCTCAAG
CGCACCATCAAGGCCATTGCGCAGCAACGGGGCAAGCTAGCCAGTTTCATGGCCAAGCCTTTCCCCGGCCAGGCCGGCAG
CGGTTTGCATGTGCATGTGAGCCTGCTCGATGCCGCCGGGCACAACGTGCTGGCCAGCGCCGCCGACGCGCCTGCGCAGT
CGCTACGCCACGCCATCGCCGGGCTACAGCGGCATGCAGATGCCTCGCTCTTGATGTTCGCCCCGCATGCCAACAGCTAT
CGCCGCTTCGTCAGCAATGCGTTCGTGCCGCTGGATGCGAGCTGGGGCTTCAACAACCGTACCGTGGCACTGCGCATCCC
GCACAGCGATGCGCACAACACCCGCATCGAACACCGCATTGCCGGCGCCGATGCCAACCCATATCTGGCCGCTGCAGCCG
TGCTGGCCGCGATGCTGGACGGCCTGCGGCAGCCGGCCGAACCCACCGCGCCGGTCACCGGCAATGCGTACGCACAGTCG
GTGTTCGCCCCACGCAGCTGGCAAGGCGCGGTGGATGCGTTCCTCGGCAGCGACTTCATCGGCGAGCAGTTCGGCACGCA
GTTCCAGCACGTATTCGGCCAGCAGAAACAACGCGAGCTGCTCGACTACCAGGCGCAGGTACCGGACCTGGATTACGCGC
GGTACCTGCGCACCGTGTGA

Upstream 100 bases:

>100_bases
AGTTACCGCGCCATCGCCGGCATTGCCAGGCGCGCCAGTGCGCTTGCGATTGCTCACGCGCGCTTTGCTACGCTGCGCGG
CGACTTCGCAGGTGTTGCCC

Downstream 100 bases:

>100_bases
TGGCTCGCCCGCACGCGCCACTGCCGCACAGCAACTCGCCGGGCAACGGGTATCCGGACAGCTGGTACGCACGCAGCACG
CCAGCCCTACCCCAACAATC

Product: glutamine synthase

Products: NA

Alternate protein names: Gamma-Glu-Put synthetase; Glutamate--putrescine ligase [H]

Number of amino acids: Translated: 459; Mature: 458

Protein sequence:

>459_residues
MASETSVASLPAADAHTLSRIAGCESVDLLLPDTNGVLRGKRVTADALSKVYRDGVCLPMSLIATDITGNTVEETGLGYA
IGDADRICRPIEGSLRLVPWAPRPMAQLLLAMHTPEGGLFEVAPRAVLQRVLQGFGALGLTPVIAVELEFYLFDAVADAQ
GRPQTPRDPITGERSDSTQVYSLQDLDDQRGFTDAVTVACRQQGIPADTAVAEYAPGQFEINLQHRADAVAACDEAVLLK
RTIKAIAQQRGKLASFMAKPFPGQAGSGLHVHVSLLDAAGHNVLASAADAPAQSLRHAIAGLQRHADASLLMFAPHANSY
RRFVSNAFVPLDASWGFNNRTVALRIPHSDAHNTRIEHRIAGADANPYLAAAAVLAAMLDGLRQPAEPTAPVTGNAYAQS
VFAPRSWQGAVDAFLGSDFIGEQFGTQFQHVFGQQKQRELLDYQAQVPDLDYARYLRTV

Sequences:

>Translated_459_residues
MASETSVASLPAADAHTLSRIAGCESVDLLLPDTNGVLRGKRVTADALSKVYRDGVCLPMSLIATDITGNTVEETGLGYA
IGDADRICRPIEGSLRLVPWAPRPMAQLLLAMHTPEGGLFEVAPRAVLQRVLQGFGALGLTPVIAVELEFYLFDAVADAQ
GRPQTPRDPITGERSDSTQVYSLQDLDDQRGFTDAVTVACRQQGIPADTAVAEYAPGQFEINLQHRADAVAACDEAVLLK
RTIKAIAQQRGKLASFMAKPFPGQAGSGLHVHVSLLDAAGHNVLASAADAPAQSLRHAIAGLQRHADASLLMFAPHANSY
RRFVSNAFVPLDASWGFNNRTVALRIPHSDAHNTRIEHRIAGADANPYLAAAAVLAAMLDGLRQPAEPTAPVTGNAYAQS
VFAPRSWQGAVDAFLGSDFIGEQFGTQFQHVFGQQKQRELLDYQAQVPDLDYARYLRTV
>Mature_458_residues
ASETSVASLPAADAHTLSRIAGCESVDLLLPDTNGVLRGKRVTADALSKVYRDGVCLPMSLIATDITGNTVEETGLGYAI
GDADRICRPIEGSLRLVPWAPRPMAQLLLAMHTPEGGLFEVAPRAVLQRVLQGFGALGLTPVIAVELEFYLFDAVADAQG
RPQTPRDPITGERSDSTQVYSLQDLDDQRGFTDAVTVACRQQGIPADTAVAEYAPGQFEINLQHRADAVAACDEAVLLKR
TIKAIAQQRGKLASFMAKPFPGQAGSGLHVHVSLLDAAGHNVLASAADAPAQSLRHAIAGLQRHADASLLMFAPHANSYR
RFVSNAFVPLDASWGFNNRTVALRIPHSDAHNTRIEHRIAGADANPYLAAAAVLAAMLDGLRQPAEPTAPVTGNAYAQSV
FAPRSWQGAVDAFLGSDFIGEQFGTQFQHVFGQQKQRELLDYQAQVPDLDYARYLRTV

Specific function: Involved in the breakdown of putrescine via the biosynthesis of gamma-L-glutamylputrescine [H]

COG id: COG0174

COG function: function code E; Glutamine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutamine synthetase family [H]

Homologues:

Organism=Homo sapiens, GI221307485, Length=419, Percent_Identity=25.0596658711217, Blast_Score=104, Evalue=2e-22,
Organism=Escherichia coli, GI87081870, Length=442, Percent_Identity=42.3076923076923, Blast_Score=346, Evalue=2e-96,
Organism=Escherichia coli, GI1790301, Length=301, Percent_Identity=28.9036544850498, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008147
- InterPro:   IPR014746
- InterPro:   IPR008146 [H]

Pfam domain/function: PF00120 Gln-synt_C [H]

EC number: =6.3.1.11 [H]

Molecular weight: Translated: 49191; Mature: 49060

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00181 GLNA_ATP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASETSVASLPAADAHTLSRIAGCESVDLLLPDTNGVLRGKRVTADALSKVYRDGVCLPM
CCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEECHHHHHHHHHCCCCCCH
SLIATDITGNTVEETGLGYAIGDADRICRPIEGSLRLVPWAPRPMAQLLLAMHTPEGGLF
HHHHCCCCCCCHHHCCCCEEECCHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCEE
EVAPRAVLQRVLQGFGALGLTPVIAVELEFYLFDAVADAQGRPQTPRDPITGERSDSTQV
HHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE
YSLQDLDDQRGFTDAVTVACRQQGIPADTAVAEYAPGQFEINLQHRADAVAACDEAVLLK
EEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHH
RTIKAIAQQRGKLASFMAKPFPGQAGSGLHVHVSLLDAAGHNVLASAADAPAQSLRHAIA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCHHHHCCCCHHHHHHHHHH
GLQRHADASLLMFAPHANSYRRFVSNAFVPLDASWGFNNRTVALRIPHSDAHNTRIEHRI
HHHHCCCCEEEEECCCCHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHEE
AGADANPYLAAAAVLAAMLDGLRQPAEPTAPVTGNAYAQSVFAPRSWQGAVDAFLGSDFI
ECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHCCHHH
GEQFGTQFQHVFGQQKQRELLDYQAQVPDLDYARYLRTV
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHCC
>Mature Secondary Structure 
ASETSVASLPAADAHTLSRIAGCESVDLLLPDTNGVLRGKRVTADALSKVYRDGVCLPM
CCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCCEECHHHHHHHHHCCCCCCH
SLIATDITGNTVEETGLGYAIGDADRICRPIEGSLRLVPWAPRPMAQLLLAMHTPEGGLF
HHHHCCCCCCCHHHCCCCEEECCHHHHCCCCCCCEEEECCCCCHHHHHHHHHCCCCCCEE
EVAPRAVLQRVLQGFGALGLTPVIAVELEFYLFDAVADAQGRPQTPRDPITGERSDSTQV
HHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEE
YSLQDLDDQRGFTDAVTVACRQQGIPADTAVAEYAPGQFEINLQHRADAVAACDEAVLLK
EEECCCCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHH
RTIKAIAQQRGKLASFMAKPFPGQAGSGLHVHVSLLDAAGHNVLASAADAPAQSLRHAIA
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCCHHHHCCCCHHHHHHHHHH
GLQRHADASLLMFAPHANSYRRFVSNAFVPLDASWGFNNRTVALRIPHSDAHNTRIEHRI
HHHHCCCCEEEEECCCCHHHHHHHHCCCEEEECCCCCCCCEEEEECCCCCCCCCCHHHEE
AGADANPYLAAAAVLAAMLDGLRQPAEPTAPVTGNAYAQSVFAPRSWQGAVDAFLGSDFI
ECCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHCCHHH
GEQFGTQFQHVFGQQKQRELLDYQAQVPDLDYARYLRTV
HHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]