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The map label for this gene is gluQ

Identifier: 21243134

GI number: 21243134

Start: 2796385

End: 2797284

Strand: Direct

Name: gluQ

Synonym: XAC2400

Alternate gene names: 21243134

Gene position: 2796385-2797284 (Clockwise)

Preceding gene: 21243132

Following gene: 21243135

Centisome position: 54.03

GC content: 70.33

Gene sequence:

>900_bases
ATGCCTTCGCCCCCTTATCTCGGCCGCTTCGCGCCCTCGCCCACCGGCCCCCTGCACTTCGGCTCCCTGCTGGCTGCATT
CGGCAGCTGGCTGCTGGCCCGGCATGCCGGTGGGCAGTGGTGCGTGCGCATCGAAGACATCGATCCGCCGCGTGCCGAGC
CCGGTGCCTGTGAACGTCAGCTGCGCACGCTGGCCGCATTCGGGCTGCACTCGGACCTGCCGGTAATTCGGCAGTCCGAG
CGCGATGCGGCCTACACCGCGGCAATCACCCGGCTGCTGCAGACCGGCCAGGCATTCGAATGCAGCTGCAGCCGTGCCGA
TCTGGCCGGCATGGGCGGCATCCACCACGCCTGCGTTGCGCCGCTGGGCGAGCGCCGTGCGGTGCGCCTGCGGGTGCCGC
CGCAACCACCGGTCGGCTTCGACGACGCCTTACAAGGCCCGGTACTGCAGGATGTCTACGCCGAGGTGGGCGATGTGGTG
TTGCGCCGCGCCGATGGGTATTGGGCGTACCAACTGGCGGTGGTGGTGGACGATGCGGCGCAGGGCATCACCGACGTGGT
GCGCGGCGCCGACCTGCTCGACTCCACCCCGCGCCAGATGGTGCTGCAGCGCGCACTGGGCCTGCCGCAGCCGCGCTACT
TGCACCTGCCGCTGATGCTGGATCGCGACGGCCGCAAGCTGTCCAAGTCACACGATGCACCCGCGCTGGACGACGCCGAT
CCACTGCCGGCCCTGCACGCCGCCTGGGCGGCCCTGGGTCAAGAGTCCGACGCGCTGCCGCGGCATGCAGCCGTGGAAAC
CGTGCTGCAGCACGCCGTGCAGCATTTTTCGCCACGGCTGCTTCCGCGCCAACGCGAGCTGGACCTCGATGAGCGCGCAT
CCGGCCTCCAGCGTGACTAG

Upstream 100 bases:

>100_bases
CATGGCGCGATGGCTCCACGGATGCGGGGTGAACTGTTGCGGATCTGCGGGTGTTGCGGCTTGAAATCAAGCAAGCACCT
GACCGACGATTCAGCTGCCC

Downstream 100 bases:

>100_bases
AATTGCGGCCCAGCAACGGCATCCGGGCGCAGCACCCCGCGCCCCAATCGCCCTCAGCCTCACTTGTTGATTGGAGTCGT
CATGACATCTCGCGTCGCAT

Product: aminoacyl-tRNA synthetase:glutamyl-like protein

Products: NA

Alternate protein names: Glu-Q-RSs

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MPSPPYLGRFAPSPTGPLHFGSLLAAFGSWLLARHAGGQWCVRIEDIDPPRAEPGACERQLRTLAAFGLHSDLPVIRQSE
RDAAYTAAITRLLQTGQAFECSCSRADLAGMGGIHHACVAPLGERRAVRLRVPPQPPVGFDDALQGPVLQDVYAEVGDVV
LRRADGYWAYQLAVVVDDAAQGITDVVRGADLLDSTPRQMVLQRALGLPQPRYLHLPLMLDRDGRKLSKSHDAPALDDAD
PLPALHAAWAALGQESDALPRHAAVETVLQHAVQHFSPRLLPRQRELDLDERASGLQRD

Sequences:

>Translated_299_residues
MPSPPYLGRFAPSPTGPLHFGSLLAAFGSWLLARHAGGQWCVRIEDIDPPRAEPGACERQLRTLAAFGLHSDLPVIRQSE
RDAAYTAAITRLLQTGQAFECSCSRADLAGMGGIHHACVAPLGERRAVRLRVPPQPPVGFDDALQGPVLQDVYAEVGDVV
LRRADGYWAYQLAVVVDDAAQGITDVVRGADLLDSTPRQMVLQRALGLPQPRYLHLPLMLDRDGRKLSKSHDAPALDDAD
PLPALHAAWAALGQESDALPRHAAVETVLQHAVQHFSPRLLPRQRELDLDERASGLQRD
>Mature_298_residues
PSPPYLGRFAPSPTGPLHFGSLLAAFGSWLLARHAGGQWCVRIEDIDPPRAEPGACERQLRTLAAFGLHSDLPVIRQSER
DAAYTAAITRLLQTGQAFECSCSRADLAGMGGIHHACVAPLGERRAVRLRVPPQPPVGFDDALQGPVLQDVYAEVGDVVL
RRADGYWAYQLAVVVDDAAQGITDVVRGADLLDSTPRQMVLQRALGLPQPRYLHLPLMLDRDGRKLSKSHDAPALDDADP
LPALHAAWAALGQESDALPRHAAVETVLQHAVQHFSPRLLPRQRELDLDERASGLQRD

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily

Homologues:

Organism=Homo sapiens, GI134288884, Length=248, Percent_Identity=36.2903225806452, Blast_Score=131, Evalue=6e-31,
Organism=Escherichia coli, GI226510925, Length=285, Percent_Identity=47.3684210526316, Blast_Score=236, Evalue=2e-63,
Organism=Escherichia coli, GI1788743, Length=247, Percent_Identity=36.8421052631579, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI71993394, Length=313, Percent_Identity=32.2683706070287, Blast_Score=127, Evalue=8e-30,
Organism=Saccharomyces cerevisiae, GI6324540, Length=264, Percent_Identity=35.2272727272727, Blast_Score=147, Evalue=2e-36,
Organism=Drosophila melanogaster, GI24665321, Length=249, Percent_Identity=35.7429718875502, Blast_Score=137, Evalue=8e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLUQ_XANAC (Q8PJX7)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642716.1
- ProteinModelPortal:   Q8PJX7
- SMR:   Q8PJX7
- GeneID:   1156471
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2400
- NMPDR:   fig|190486.1.peg.2360
- HOGENOM:   HBG628189
- OMA:   DWPRDPD
- ProtClustDB:   PRK05710
- BioCyc:   XAXO190486:XAC2400-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01428
- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR03838

Pfam domain/function: PF00749 tRNA-synt_1c

EC number: NA

Molecular weight: Translated: 32522; Mature: 32391

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 45-45 BINDING 170-170 BINDING 188-188 BINDING 229-229

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPPYLGRFAPSPTGPLHFGSLLAAFGSWLLARHAGGQWCVRIEDIDPPRAEPGACERQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHH
LRTLAAFGLHSDLPVIRQSERDAAYTAAITRLLQTGQAFECSCSRADLAGMGGIHHACVA
HHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHC
PLGERRAVRLRVPPQPPVGFDDALQGPVLQDVYAEVGDVVLRRADGYWAYQLAVVVDDAA
CCCCCCEEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECHHH
QGITDVVRGADLLDSTPRQMVLQRALGLPQPRYLHLPLMLDRDGRKLSKSHDAPALDDAD
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHCCCCCCCCCCC
PLPALHAAWAALGQESDALPRHAAVETVLQHAVQHFSPRLLPRQRELDLDERASGLQRD
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHCCCCCC
>Mature Secondary Structure 
PSPPYLGRFAPSPTGPLHFGSLLAAFGSWLLARHAGGQWCVRIEDIDPPRAEPGACERQ
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHHHH
LRTLAAFGLHSDLPVIRQSERDAAYTAAITRLLQTGQAFECSCSRADLAGMGGIHHACVA
HHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCHHHHHHC
PLGERRAVRLRVPPQPPVGFDDALQGPVLQDVYAEVGDVVLRRADGYWAYQLAVVVDDAA
CCCCCCEEEEECCCCCCCCCCHHHCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECHHH
QGITDVVRGADLLDSTPRQMVLQRALGLPQPRYLHLPLMLDRDGRKLSKSHDAPALDDAD
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHCCCCCCCCCCC
PLPALHAAWAALGQESDALPRHAAVETVLQHAVQHFSPRLLPRQRELDLDERASGLQRD
CCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHCCCHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217