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The map label for this gene is ykoW [H]

Identifier: 21243132

GI number: 21243132

Start: 2793239

End: 2795308

Strand: Direct

Name: ykoW [H]

Synonym: XAC2398

Alternate gene names: 21243132

Gene position: 2793239-2795308 (Clockwise)

Preceding gene: 21243131

Following gene: 21243134

Centisome position: 53.97

GC content: 64.54

Gene sequence:

>2070_bases
ATGCAAAAAGGCAAAGATCTCACCCTCCGCCTGATGATCGTCGACGACAGCGTGGAGAGTGCAGAGACCATCGTCACCGC
GCTGCGCAATGGCGGCATTGCGGTGCGTCCATCGCGACCGCAAAGCCAGGAAGAACTGGCCAGCATGCTGTCGGGCCAGA
TCGATCTGGCCATCCTGGGTCAGGCGCAGCAGATCCCCATGAGCGCCTTGCAGACCCAGATTGCAGGCAGCGGCAAGGAC
ATCCCGATCCTCTTGCTGGCCGAGCGGATCGAAGAGAACGCCCTGGTCGAGGCCGCTTCGCACGGGGTGCGCGCCATCGC
ATTGCGCCACCGCCCCGCACACTTGCTTGCATTGGTGCGCTCGGAATGGGACGACCTGCAGGCCCGCCGTGGACTGCGCC
GCATCGAAGCACAGATGCGCGAGACCGAGCGCCGCTGCGACGCACTCATCGCGTCCTCGCGCGACCCGATCGCCTACGTG
CATGAAGGCATGCATATCCGCGCCAACGATGCCTATCTGGAAATGTTCGGCTTCGAGTCGTTCGACGATGTCGAAGGCAT
CTCGCTGCTGGACATGATCGCCGCGCAGTACGTCGACGATTTCAAACAGCTGCTCAAGGCGATGTCCAAGGGCGAGCCGC
CGCCGGCGCAGTACAAGCTCGATGCACGCCGCGTGGAAGGCGACACCTTCCCGGCCACGATGGAGTTCGCCACCGCCACC
TATGAAGGCGAGCCATGCATCCAGGTGGTGTTCCGGCGCCGCGAGGAGTTCGACCCGGAACTGGCGCGCGAGGTCGAAGA
CTTGCGCCAGCGCGACCAGGTCACCGGCCTGCTCAATCGCCCCACCTTCATGGTGGCGCTGGAACAGGCCGTGGCACAGG
CCGGCCGCAGCGAGGGCCAATCCGGCTTCCTGTTGATCGAGCCGGATCACTACGCACGCATCCTGCCGGAGTTCGGGCTG
GATTCGGCCGATGCGCTGATTGCTGCGCTCGCCGCGCACGTGGCGAGCGTACTGGACGACAGCGTGTTGGCCGCGCGCTT
CGGCGAACACAGTTTCGCCCTGCTGTTGAACGGAAATTACGCGCGCACGCATGCGCTGGCGGAAACCGTGCGCAATGCGT
TCGCGCAGCACGTGTTCAGCGTGGGGACGCGCTCGGCCACGGTGACGGTCAGCATCGGCGGCGTGCAGATCGGCGAGAAG
ATCGCCAGCATCGGACAGGTACTCAATCGCGGCACCGAGGCGGTGCGCACCACTGCCGAGCTCGGTGGCAATGCGGTCAG
CATCTACGATCCGGCTGCGGCGGATCGGGCCGAGGAAGAACGCATCGAACGCTGGGTCGAGCAGTTGCGCGAAGCGCTGG
TCGGCGACGGTTTCCTGCTGCATTACCAGCCGGTGCTCAACCTGCAAGGCGAGCCGCTGGAGCTGTACCAGGCCTTCCTG
CGCCTGGAACGCAATGGCGAAATGATGTCGCCGAACGCGTTCATGGCCATTGCCGAAGAGCACGACCTGGTCACCGAAAT
CGATCGCTGGGTGGTGGCGCGGGCAATCCGGCAACTGGGCGAACGCCAGCGTGCCGGGCACAAGACCCACCTGCTGGTGC
GCATCGGACCGAACTCGTTCTCGGACCCGCAGATGATCGACACCATCCGCGAGCAATTGGCGGTCTACGGCGTTCCCGGT
GAACGGCTGTGGCTGCAGACGCCGGAGTCGAAGGTGTTTACGCACCTGCGCAACGCGCAGCAGTTCCTGGCGGCGGTGTC
GGCGATGGATTGCAAGGTCGGGCTGGAGCAATTCGGCTCGGGCCTGGACTCCTTCCAGTTGCTGGCGCATTTCCACCCGG
CCTTCCTCAAACTGGATCGTGGCATCACCGGCGACATCGCCTCGGCGCGGGACAGCCAGGAAAAGATTCGCGAAATCACC
TCGCGCGCGCAACCGGCCGGCATTCTGACAATGGCCGAATTCGTCGCCGATGCGCAGTCGATGAGCAGCTTCTTCAGTGC
CGGGGTGGACTACGTCCAGGGCGATTTCGTCGCACCGACCGGGCCGTTGATGAATTACGAGTTCGGCTGA

Upstream 100 bases:

>100_bases
TAAATATTGCTCTACGTCTCACACTTGATGCGGCATGCTCCACACACATGGACGTGCCAAACCCCTTCGTGTATTAAAGC
CCGTCTCTAGGGAGCCGCGC

Downstream 100 bases:

>100_bases
AAGCCTGCAGCGCCCGCTCGTTCGCACCATCGCTGGGCAACAAAAAACCCGCATTGCGCGGGTTTTTTGTTGCCTGCCAG
GCAGCCATACACTCGGCAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MQKGKDLTLRLMIVDDSVESAETIVTALRNGGIAVRPSRPQSQEELASMLSGQIDLAILGQAQQIPMSALQTQIAGSGKD
IPILLLAERIEENALVEAASHGVRAIALRHRPAHLLALVRSEWDDLQARRGLRRIEAQMRETERRCDALIASSRDPIAYV
HEGMHIRANDAYLEMFGFESFDDVEGISLLDMIAAQYVDDFKQLLKAMSKGEPPPAQYKLDARRVEGDTFPATMEFATAT
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQSGFLLIEPDHYARILPEFGL
DSADALIAALAAHVASVLDDSVLAARFGEHSFALLLNGNYARTHALAETVRNAFAQHVFSVGTRSATVTVSIGGVQIGEK
IASIGQVLNRGTEAVRTTAELGGNAVSIYDPAAADRAEEERIERWVEQLREALVGDGFLLHYQPVLNLQGEPLELYQAFL
RLERNGEMMSPNAFMAIAEEHDLVTEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSFSDPQMIDTIREQLAVYGVPG
ERLWLQTPESKVFTHLRNAQQFLAAVSAMDCKVGLEQFGSGLDSFQLLAHFHPAFLKLDRGITGDIASARDSQEKIREIT
SRAQPAGILTMAEFVADAQSMSSFFSAGVDYVQGDFVAPTGPLMNYEFG

Sequences:

>Translated_689_residues
MQKGKDLTLRLMIVDDSVESAETIVTALRNGGIAVRPSRPQSQEELASMLSGQIDLAILGQAQQIPMSALQTQIAGSGKD
IPILLLAERIEENALVEAASHGVRAIALRHRPAHLLALVRSEWDDLQARRGLRRIEAQMRETERRCDALIASSRDPIAYV
HEGMHIRANDAYLEMFGFESFDDVEGISLLDMIAAQYVDDFKQLLKAMSKGEPPPAQYKLDARRVEGDTFPATMEFATAT
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQSGFLLIEPDHYARILPEFGL
DSADALIAALAAHVASVLDDSVLAARFGEHSFALLLNGNYARTHALAETVRNAFAQHVFSVGTRSATVTVSIGGVQIGEK
IASIGQVLNRGTEAVRTTAELGGNAVSIYDPAAADRAEEERIERWVEQLREALVGDGFLLHYQPVLNLQGEPLELYQAFL
RLERNGEMMSPNAFMAIAEEHDLVTEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSFSDPQMIDTIREQLAVYGVPG
ERLWLQTPESKVFTHLRNAQQFLAAVSAMDCKVGLEQFGSGLDSFQLLAHFHPAFLKLDRGITGDIASARDSQEKIREIT
SRAQPAGILTMAEFVADAQSMSSFFSAGVDYVQGDFVAPTGPLMNYEFG
>Mature_689_residues
MQKGKDLTLRLMIVDDSVESAETIVTALRNGGIAVRPSRPQSQEELASMLSGQIDLAILGQAQQIPMSALQTQIAGSGKD
IPILLLAERIEENALVEAASHGVRAIALRHRPAHLLALVRSEWDDLQARRGLRRIEAQMRETERRCDALIASSRDPIAYV
HEGMHIRANDAYLEMFGFESFDDVEGISLLDMIAAQYVDDFKQLLKAMSKGEPPPAQYKLDARRVEGDTFPATMEFATAT
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQSGFLLIEPDHYARILPEFGL
DSADALIAALAAHVASVLDDSVLAARFGEHSFALLLNGNYARTHALAETVRNAFAQHVFSVGTRSATVTVSIGGVQIGEK
IASIGQVLNRGTEAVRTTAELGGNAVSIYDPAAADRAEEERIERWVEQLREALVGDGFLLHYQPVLNLQGEPLELYQAFL
RLERNGEMMSPNAFMAIAEEHDLVTEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSFSDPQMIDTIREQLAVYGVPG
ERLWLQTPESKVFTHLRNAQQFLAAVSAMDCKVGLEQFGSGLDSFQLLAHFHPAFLKLDRGITGDIASARDSQEKIREIT
SRAQPAGILTMAEFVADAQSMSSFFSAGVDYVQGDFVAPTGPLMNYEFG

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=423, Percent_Identity=24.113475177305, Blast_Score=111, Evalue=2e-25,
Organism=Escherichia coli, GI1788849, Length=242, Percent_Identity=26.0330578512397, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI87081921, Length=427, Percent_Identity=23.1850117096019, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI1790496, Length=236, Percent_Identity=22.8813559322034, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788381, Length=432, Percent_Identity=22.6851851851852, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI226510982, Length=436, Percent_Identity=23.394495412844, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI87082096, Length=238, Percent_Identity=21.4285714285714, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI87081980, Length=233, Percent_Identity=27.0386266094421, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1789650, Length=347, Percent_Identity=22.478386167147, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 76016; Mature: 76016

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKGKDLTLRLMIVDDSVESAETIVTALRNGGIAVRPSRPQSQEELASMLSGQIDLAILG
CCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCCEEEEC
QAQQIPMSALQTQIAGSGKDIPILLLAERIEENALVEAASHGVRAIALRHRPAHLLALVR
CCHHCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
SEWDDLQARRGLRRIEAQMRETERRCDALIASSRDPIAYVHEGMHIRANDAYLEMFGFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECCCEEEEECCCC
FDDVEGISLLDMIAAQYVDDFKQLLKAMSKGEPPPAQYKLDARRVEGDTFPATMEFATAT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCCCCCCCCHHHEEEE
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQ
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
SGFLLIEPDHYARILPEFGLDSADALIAALAAHVASVLDDSVLAARFGEHSFALLLNGNY
CCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCH
ARTHALAETVRNAFAQHVFSVGTRSATVTVSIGGVQIGEKIASIGQVLNRGTEAVRTTAE
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHH
LGGNAVSIYDPAAADRAEEERIERWVEQLREALVGDGFLLHYQPVLNLQGEPLELYQAFL
HCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHHHHHHHH
RLERNGEMMSPNAFMAIAEEHDLVTEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSF
HHHCCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
SDPQMIDTIREQLAVYGVPGERLWLQTPESKVFTHLRNAQQFLAAVSAMDCKVGLEQFGS
CCCHHHHHHHHHHHEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLDSFQLLAHFHPAFLKLDRGITGDIASARDSQEKIREITSRAQPAGILTMAEFVADAQS
CCHHHHHHHHHCHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MSSFFSAGVDYVQGDFVAPTGPLMNYEFG
HHHHHHHCCHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQKGKDLTLRLMIVDDSVESAETIVTALRNGGIAVRPSRPQSQEELASMLSGQIDLAILG
CCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCCEEEEC
QAQQIPMSALQTQIAGSGKDIPILLLAERIEENALVEAASHGVRAIALRHRPAHLLALVR
CCHHCCHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHH
SEWDDLQARRGLRRIEAQMRETERRCDALIASSRDPIAYVHEGMHIRANDAYLEMFGFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECCCEEEEECCCC
FDDVEGISLLDMIAAQYVDDFKQLLKAMSKGEPPPAQYKLDARRVEGDTFPATMEFATAT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCCCCCCCCHHHEEEE
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQ
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
SGFLLIEPDHYARILPEFGLDSADALIAALAAHVASVLDDSVLAARFGEHSFALLLNGNY
CCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCH
ARTHALAETVRNAFAQHVFSVGTRSATVTVSIGGVQIGEKIASIGQVLNRGTEAVRTTAE
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHH
LGGNAVSIYDPAAADRAEEERIERWVEQLREALVGDGFLLHYQPVLNLQGEPLELYQAFL
HCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHHHHHHHH
RLERNGEMMSPNAFMAIAEEHDLVTEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSF
HHHCCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
SDPQMIDTIREQLAVYGVPGERLWLQTPESKVFTHLRNAQQFLAAVSAMDCKVGLEQFGS
CCCHHHHHHHHHHHEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GLDSFQLLAHFHPAFLKLDRGITGDIASARDSQEKIREITSRAQPAGILTMAEFVADAQS
CCHHHHHHHHHCHHHHHCCCCCCCCHHHCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MSSFFSAGVDYVQGDFVAPTGPLMNYEFG
HHHHHHHCCHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]