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The map label for this gene is cmk

Identifier: 21243034

GI number: 21243034

Start: 2689759

End: 2690442

Strand: Reverse

Name: cmk

Synonym: XAC2299

Alternate gene names: 21243034

Gene position: 2690442-2689759 (Counterclockwise)

Preceding gene: 21243041

Following gene: 21243033

Centisome position: 51.98

GC content: 65.64

Gene sequence:

>684_bases
ATGACCGACCTGTCGCCCGTCCTCACCATCGATGGCCCCTCCGGTGCCGGCAAGGGCACCGTGAGCCGGATCGTGGCCGC
CCGGCTGGGCTGGCATTACCTCGATTCGGGTGCACTGTATCGCGCTGTCGGAGTCGCTGCGAGCTGGGCCGACCTGGATG
TCTCCGACCCGGCAGCGCTGGTGCGCTGCACCTTCGACACCAAGGTGGAATTCGACGATGCGGGAGAGGCAGGGTTGCGC
GTGCTGGTCAATGGCGCAGACGCGACCGGTGAGCTGCGCCTGGAAACTACCGGCGCGCTGGCCTCGGCCATTGCGGCCAT
TCCCGAGGTTCGCAGCGCCCTGAAGGAGCGCCAACGCGCATTCAGGCGCGCGCCCGGCCTGGTTGCCGACGGGCGCGACA
TGGGCACGGTGATCTTTCCCGATGCTGCCTACAAGGTGTTTCTGACCGCCAGTGCCGAAGAACGTGCGGGTCGTCGCCAT
AAACAGTTGATGGAAAAGGGTGTTCCGGTTATCTTTGATGACCTGCTGCGCGAGATCATGGCCCGTGATGCCCGTGATGC
GCAGCGGGTGGTGGCGCCATTGCGGCCGGCCGAAGACGCCGTGCTGATCGATACCAGCGGAATGGGAATCGAAGATGTCG
TCCAGCGTGTGGTCGGGTTGCTCGCAGGCCGCACGCCGTCGTAA

Upstream 100 bases:

>100_bases
CGGCAATTCTAACCGGCTTTTCGTCGTGCTTTCAAGTGGTTGCAGCGCGATCGCGGCGAGCGGCGCTACACTACGGACTG
ATGACCTTCCGGAAACCTGA

Downstream 100 bases:

>100_bases
GCGTTTCGCAAGCGGGTTTGCCCCGCCGACCGTAAGGCGTTCCAAAGCTCCGTCGCGCATCCTGCGTGGCGGTTCTATGA
CTTCCAACCGACTCGCTGTC

Product: cytidylate kinase

Products: NA

Alternate protein names: CK; Cytidine monophosphate kinase; CMP kinase

Number of amino acids: Translated: 227; Mature: 226

Protein sequence:

>227_residues
MTDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAALVRCTFDTKVEFDDAGEAGLR
VLVNGADATGELRLETTGALASAIAAIPEVRSALKERQRAFRRAPGLVADGRDMGTVIFPDAAYKVFLTASAEERAGRRH
KQLMEKGVPVIFDDLLREIMARDARDAQRVVAPLRPAEDAVLIDTSGMGIEDVVQRVVGLLAGRTPS

Sequences:

>Translated_227_residues
MTDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAALVRCTFDTKVEFDDAGEAGLR
VLVNGADATGELRLETTGALASAIAAIPEVRSALKERQRAFRRAPGLVADGRDMGTVIFPDAAYKVFLTASAEERAGRRH
KQLMEKGVPVIFDDLLREIMARDARDAQRVVAPLRPAEDAVLIDTSGMGIEDVVQRVVGLLAGRTPS
>Mature_226_residues
TDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAALVRCTFDTKVEFDDAGEAGLRV
LVNGADATGELRLETTGALASAIAAIPEVRSALKERQRAFRRAPGLVADGRDMGTVIFPDAAYKVFLTASAEERAGRRHK
QLMEKGVPVIFDDLLREIMARDARDAQRVVAPLRPAEDAVLIDTSGMGIEDVVQRVVGLLAGRTPS

Specific function: ATP, Datp, And GTP Are Equally Effective As Phosphate Donors. CMP And Dcmp Are The Best Phosphate Acceptors. [C]

COG id: COG0283

COG function: function code F; Cytidylate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidylate kinase family. Type 1 subfamily

Homologues:

Organism=Escherichia coli, GI1787139, Length=218, Percent_Identity=51.8348623853211, Blast_Score=216, Evalue=7e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KCY_XANAC (Q8PK76)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642616.1
- ProteinModelPortal:   Q8PK76
- SMR:   Q8PK76
- GeneID:   1156370
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2299
- NMPDR:   fig|190486.1.peg.2260
- HOGENOM:   HBG354377
- OMA:   DIGTVIC
- ProtClustDB:   PRK00023
- BioCyc:   XAXO190486:XAC2299-MONOMER
- BRENDA:   2.7.4.14
- GO:   GO:0005737
- HAMAP:   MF_00238
- InterPro:   IPR003136
- InterPro:   IPR011994
- PANTHER:   PTHR21299:SF2
- TIGRFAMs:   TIGR00017

Pfam domain/function: PF02224 Cytidylate_kin

EC number: =2.7.4.14

Molecular weight: Translated: 24096; Mature: 23965

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAAL
CCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEE
VRCTFDTKVEFDDAGEAGLRVLVNGADATGELRLETTGALASAIAAIPEVRSALKERQRA
EEEECCCEECCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
FRRAPGLVADGRDMGTVIFPDAAYKVFLTASAEERAGRRHKQLMEKGVPVIFDDLLREIM
HHHCCCCEECCCCCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ARDARDAQRVVAPLRPAEDAVLIDTSGMGIEDVVQRVVGLLAGRTPS
HCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TDLSPVLTIDGPSGAGKGTVSRIVAARLGWHYLDSGALYRAVGVAASWADLDVSDPAAL
CCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEE
VRCTFDTKVEFDDAGEAGLRVLVNGADATGELRLETTGALASAIAAIPEVRSALKERQRA
EEEECCCEECCCCCCCCCEEEEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHH
FRRAPGLVADGRDMGTVIFPDAAYKVFLTASAEERAGRRHKQLMEKGVPVIFDDLLREIM
HHHCCCCEECCCCCCEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHH
ARDARDAQRVVAPLRPAEDAVLIDTSGMGIEDVVQRVVGLLAGRTPS
HCCCHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217