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The map label for this gene is ttgC [H]

Identifier: 21242883

GI number: 21242883

Start: 2507090

End: 2508574

Strand: Direct

Name: ttgC [H]

Synonym: XAC2148

Alternate gene names: 21242883

Gene position: 2507090-2508574 (Clockwise)

Preceding gene: 21242882

Following gene: 77748631

Centisome position: 48.44

GC content: 69.56

Gene sequence:

>1485_bases
ATGACAGACGTTCGCAACGCATTGCTCGCCAGTGCCGTGGCGGCATCGCTCGCCGCCTGCGCAGTAGGACCGGACTTTCA
GCGCCCCGCTGCGCCTGCTGCCGATCGCTACACCGCCAACGCGTTACCGGTAACGACCGCAGCCGCCGACGTAGCACATG
GTGGTGCGCAAGAGTTCGAGCCTGGGCAGGAACTGCCGGCCGCCTGGTGGCGCGCATTCGGCTCGCCGCAACTGAATGCT
GTGGTGGAGCGGGCATTGCGTGCCAATCCGGATCTGCAAGCCGCCGACGCAGCGCTTCGCCAGGCGCAACAGACGCTGGC
CGCGCAACGCGGTGCCTGGCGACCGCAAGCGGATCTGCGTGTGGATGCCAGCCGGCAACGCGACTCGGTGGTGCCGGCGC
CGGATGCCGGCATCGACACACCGTATGCGCTACGCACCGCCCAACTCAGCGTCAGCTATACGCTGGACGTGTTTGGCGGC
ACGCGGCGGCAAGTGGAAGCGGCGGGTGCGCAGGCACAGGCGCAGCGCGATCAGCGCGATGCGGCGTACCTGAGCCTCAC
CGCCAACGTGGTGAACGCGGCCATCGGCGAAGCGGCCGTGCGCGCGCAACTGGATGCGGCGCGCGCGCAGGTCGCCATCG
CCAAGCAGCTCTGCACGCTCACCGCGCGCCAGCAGGCGCTTGGCGCACTCGGCGCAGCGCAGGTGCTGGCCCAACGCACT
GCGCTGGCACAGGCGCAGGCCGCGGTGCCGGCACTGGAAAAGCAGCTGGAACAACAACGGACCCTGCTCGCGATTCTGGG
CGGGCAACTGCCTGGCGACGCTGCGGGTGAGGCATTTACGCTGGATACCTTGCAGCTTCCGGCGCAACTGCCGTTATCGT
TGCCCTCGCGGTTGCTCGATCGCCGCCCGGACATCCGCGCCGCCGAAGCGCAGGCGCATGCTGCCAGCGCATTGATCGGC
GTGGCGGCGGCTGCGCGCTTGCCGTCCATTAGCTTAAGTGCGGCCAGCGGCGGCTCTGCATCCGGTGTCGGGCGCATGTT
CGCGGCCGGCAATACGCAATGGTCGGTGGCCGGCGGCCTGCTGCAGCCACTGTTCCATGGCGGCGCACTTGCGCATCAGC
AACGGGCGGCCGAAGCTGGCTACACGCAGGCCATGGCGCAGTACCGCAGCGTGGTGTTGAACGCATTTGGCGAGGTTTCC
AACGCGCTCACCGCGCTGCAGAGCGACGCGCAGAGCCTGCACGCCTGTGCCGATGCGCAAGCGCTGGCGGAGCGCACGCT
GGCGCTGGTGCGACGTCAACAGGCGGTTGGTGCGGTGGGCATGGCGGATCTGCTGCAGGCGCAGCAGGCCTACCAGAGCA
CGCAGGCCGCCACGGTCCAGGCACAGGCCGCGCGCTACACCGACACCGTGGCGCTGTATCAGGCCCTGGGTGGCGGGCCG
TGGTGGTCGCCAGCGGCCCGCACGCCCAAGCCCGCGGTTCCATGA

Upstream 100 bases:

>100_bases
TGGTCACCGCCACGCTACTCACCTTGGTGTTGTTGCCATCGCTGTACTACCTGATGGAAGCCTTCGTCGCAACGCGCCAG
GGCCGTCAGGGGACGACACC

Downstream 100 bases:

>100_bases
ATCACGCGCTGCATCCAGCGCCGGTTGCGTAACGGCGGCGCCGCCAGCTGAGACAATCGCCGCCATGCGCATGACCTCTC
TCTTCCGCTCGCCACCCACG

Product: outer membrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MTDVRNALLASAVAASLAACAVGPDFQRPAAPAADRYTANALPVTTAAADVAHGGAQEFEPGQELPAAWWRAFGSPQLNA
VVERALRANPDLQAADAALRQAQQTLAAQRGAWRPQADLRVDASRQRDSVVPAPDAGIDTPYALRTAQLSVSYTLDVFGG
TRRQVEAAGAQAQAQRDQRDAAYLSLTANVVNAAIGEAAVRAQLDAARAQVAIAKQLCTLTARQQALGALGAAQVLAQRT
ALAQAQAAVPALEKQLEQQRTLLAILGGQLPGDAAGEAFTLDTLQLPAQLPLSLPSRLLDRRPDIRAAEAQAHAASALIG
VAAAARLPSISLSAASGGSASGVGRMFAAGNTQWSVAGGLLQPLFHGGALAHQQRAAEAGYTQAMAQYRSVVLNAFGEVS
NALTALQSDAQSLHACADAQALAERTLALVRRQQAVGAVGMADLLQAQQAYQSTQAATVQAQAARYTDTVALYQALGGGP
WWSPAARTPKPAVP

Sequences:

>Translated_494_residues
MTDVRNALLASAVAASLAACAVGPDFQRPAAPAADRYTANALPVTTAAADVAHGGAQEFEPGQELPAAWWRAFGSPQLNA
VVERALRANPDLQAADAALRQAQQTLAAQRGAWRPQADLRVDASRQRDSVVPAPDAGIDTPYALRTAQLSVSYTLDVFGG
TRRQVEAAGAQAQAQRDQRDAAYLSLTANVVNAAIGEAAVRAQLDAARAQVAIAKQLCTLTARQQALGALGAAQVLAQRT
ALAQAQAAVPALEKQLEQQRTLLAILGGQLPGDAAGEAFTLDTLQLPAQLPLSLPSRLLDRRPDIRAAEAQAHAASALIG
VAAAARLPSISLSAASGGSASGVGRMFAAGNTQWSVAGGLLQPLFHGGALAHQQRAAEAGYTQAMAQYRSVVLNAFGEVS
NALTALQSDAQSLHACADAQALAERTLALVRRQQAVGAVGMADLLQAQQAYQSTQAATVQAQAARYTDTVALYQALGGGP
WWSPAARTPKPAVP
>Mature_493_residues
TDVRNALLASAVAASLAACAVGPDFQRPAAPAADRYTANALPVTTAAADVAHGGAQEFEPGQELPAAWWRAFGSPQLNAV
VERALRANPDLQAADAALRQAQQTLAAQRGAWRPQADLRVDASRQRDSVVPAPDAGIDTPYALRTAQLSVSYTLDVFGGT
RRQVEAAGAQAQAQRDQRDAAYLSLTANVVNAAIGEAAVRAQLDAARAQVAIAKQLCTLTARQQALGALGAAQVLAQRTA
LAQAQAAVPALEKQLEQQRTLLAILGGQLPGDAAGEAFTLDTLQLPAQLPLSLPSRLLDRRPDIRAAEAQAHAASALIGV
AAAARLPSISLSAASGGSASGVGRMFAAGNTQWSVAGGLLQPLFHGGALAHQQRAAEAGYTQAMAQYRSVVLNAFGEVSN
ALTALQSDAQSLHACADAQALAERTLALVRRQQAVGAVGMADLLQAQQAYQSTQAATVQAQAARYTDTVALYQALGGGPW
WSPAARTPKPAVP

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=484, Percent_Identity=25.6198347107438, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI2367348, Length=451, Percent_Identity=26.3858093126386, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 50985; Mature: 50854

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDVRNALLASAVAASLAACAVGPDFQRPAAPAADRYTANALPVTTAAADVAHGGAQEFE
CCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
PGQELPAAWWRAFGSPQLNAVVERALRANPDLQAADAALRQAQQTLAAQRGAWRPQADLR
CCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
VDASRQRDSVVPAPDAGIDTPYALRTAQLSVSYTLDVFGGTRRQVEAAGAQAQAQRDQRD
ECCCCCCCCCCCCCCCCCCCCHHEEEEEEEEEEEEEECCCCHHHHHHHCHHHHHHHHHHH
AAYLSLTANVVNAAIGEAAVRAQLDAARAQVAIAKQLCTLTARQQALGALGAAQVLAQRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAQAQAAVPALEKQLEQQRTLLAILGGQLPGDAAGEAFTLDTLQLPAQLPLSLPSRLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHCCCCCCCCHHHHHHH
RRPDIRAAEAQAHAASALIGVAAAARLPSISLSAASGGSASGVGRMFAAGNTQWSVAGGL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHCCCCCCCHHHHHH
LQPLFHGGALAHQQRAAEAGYTQAMAQYRSVVLNAFGEVSNALTALQSDAQSLHACADAQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAERTLALVRRQQAVGAVGMADLLQAQQAYQSTQAATVQAQAARYTDTVALYQALGGGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WWSPAARTPKPAVP
CCCCCCCCCCCCCC
>Mature Secondary Structure 
TDVRNALLASAVAASLAACAVGPDFQRPAAPAADRYTANALPVTTAAADVAHGGAQEFE
CHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCC
PGQELPAAWWRAFGSPQLNAVVERALRANPDLQAADAALRQAQQTLAAQRGAWRPQADLR
CCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
VDASRQRDSVVPAPDAGIDTPYALRTAQLSVSYTLDVFGGTRRQVEAAGAQAQAQRDQRD
ECCCCCCCCCCCCCCCCCCCCHHEEEEEEEEEEEEEECCCCHHHHHHHCHHHHHHHHHHH
AAYLSLTANVVNAAIGEAAVRAQLDAARAQVAIAKQLCTLTARQQALGALGAAQVLAQRT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAQAQAAVPALEKQLEQQRTLLAILGGQLPGDAAGEAFTLDTLQLPAQLPLSLPSRLLD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHCCCCCCCCHHHHHHH
RRPDIRAAEAQAHAASALIGVAAAARLPSISLSAASGGSASGVGRMFAAGNTQWSVAGGL
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHCCCCCCCHHHHHH
LQPLFHGGALAHQQRAAEAGYTQAMAQYRSVVLNAFGEVSNALTALQSDAQSLHACADAQ
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAERTLALVRRQQAVGAVGMADLLQAQQAYQSTQAATVQAQAARYTDTVALYQALGGGP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
WWSPAARTPKPAVP
CCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]