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The map label for this gene is syrE2 [H]

Identifier: 21242834

GI number: 21242834

Start: 2449906

End: 2455932

Strand: Direct

Name: syrE2 [H]

Synonym: XAC2098

Alternate gene names: 21242834

Gene position: 2449906-2455932 (Clockwise)

Preceding gene: 21242833

Following gene: 21242840

Centisome position: 47.34

GC content: 65.22

Gene sequence:

>6027_bases
GTGTTGCAGACGCAGGGAGTCAATCACTACCCGGTGGTGCTCGACGTAGAGGAAATGGATGACGGGATTCGCCTGACGGG
TTATTTGCCAACTGGGTATAGCGCGCTACGGCTGTGCACCTACATGCGATCGGCATTGCAGCAGCTGGCCGACGCGCTCG
AGCATGAGCGGGAGACGCCGATCAACCAGCTGTGCGTGCTGCCGCCAGCAGAGCGCCAGCGTTTGCTGGGCTTCAACCTG
CAGCATCGCGTGCCGGAGCGGATGGACACCGTGCACGGGCTGTTCGAGCGGCAGGTCGCGGCGACACCTGAGGCGGTGGC
GCTGGAGTGCGACGGCCAGCGCCTGCAGTACCGCGAGCTCGATACGCGGGCCAACCAGCTGGCGCATCGGTTGCTGCAAC
TGGGCATCGGGCCGGACGAGCGGGTGGCGATCTGCGTGCAGCGCAGTGCGGAGCTGATCATCGGCCTGCTGGCCATTCTC
AAGGCGGGCGCAGCCTATGTGCCCCTGGACCCGACCTATCCGGCCGAGCGGCTGGCGTATCTGCTGCACGACAGCGCCCC
GCGCGCGGTGCTGGTGCATGCGCCCACCCGCTCGGCGCTGGGCGCTGCGGCGCTGCCATTGATCGACATCGACAATGCCG
CCGCAGGCGAGCTGCCGTGCACCAATCCGCAGGTTCCCGGCCTGACCGCCGCGCATCTGGCGTATGTGATCTACACCTCC
GGTTCCAGCGGCCAGCCCAAGGGGGTGATGGTCGAGCATCGGCAGCTGGCGCAACTGGTGGCCTGGCACACGGCGGCCTT
CGGGGTGGGCGAGGGGACGCGCAGTTCCAGCCTGGCCGGTCTGAGCTTCGATGCGGCGGCCTGGGAGATCTGGCCAAGCC
TGTGCAGCGGTGGCGTGCTGGTGATGCCCAGCGCCGCGCACAGTGCGGATGTGGCATCCCTGCTGCAGTGGTGGCGTGCG
CAGGAGCTGGATGTGAGCTTCCTGCCCACGCCGATCGCCGAGCATGCGTTTGCCGCCGGCATGACGCCCCAGCGTCTGCG
GTGTCTGTTGGTCGGTGGCGATCGTCTGCGGCAGGTGCCCGAGGGCCTGCCGTTTAGCGTGTACAACAATTACGGTCCGA
CCGAGACGACGGTGGTGGCCAGCAGCGGCGTGGTGCCCCCTGGGGTGCCTAACCCGTCCATCGGTCGACCGCTGCCGTAC
CTGCGCGCGTATGTGCTCGATGCCCAGGGGCAGCTTGCGCCGTTGGGTGTGGTGGGTGAGCTGTATCTGGGCGGTGCAGG
GGTGGCCCGCGGGTATCTGGGGCGTGAGGCACTGACGGCCGAGCGCTTCATCGGCGACCCGTTTTATCCGGGCGCGCGGA
TGTACCGCACCGGCGATCTGTGTCGCTGGCTGGACGATGGCCGGCTGGACTATGTCGGCCGCAACGATGCGCAGGTCAAG
ATCCGTGGCCGACGCATCGAGCTGGGCGAAATCCAAGCGCATCTGCTGGCCCATCCACAGGTGCGCGAAGCGGTGGTGCT
GGCCCGCGAGGACGTGGCGGGCGAGCGGCGGCTGGTGGGGTATGTGATCGCCACCGCCGAGGCGCCGACAGCGGCCGAGC
TACAGCGGCATTTGCGCGTGCACTTGCCGGAGTACCTGGTGCCCGAGGCTTTTGTGCCAGTGGACGCGTGGCCGCTGACG
GCCAACGGCAAGCTGGATCGGCACGCATTGCCTGGGCCCGATGCCGCGCAACGCAACCTGCAGACGTATGAGCCGCCTGC
CAATGCGCTGGAGCAGCAGCTGGCCGAAATCTGGCAGGCGGTGCTGGGGGTGGAGCGGGTCGGGCGCCACGATAATTTCT
TCCAGCTCGGCGGGCACTCCCTGCTGGCGGTGACGCTGGTGGAACGGCTGCGCCAGCAGGGTCTTGGCATGGATGTGCGG
GCACTGCTGGGACAGCCCACCTTGGCGGCAACGGCCGCAGCGCTTGGCCGCAGCCAGGAACTGGAGGTGCCGCCGAACCT
GATACCGGCCGGCTGCGCACGCATTACCCCGGAGCTGCTGACACTGGTGGAGTTGTCGCAGGCCACGATCGATCGCATCG
TGGCCACAGTGCCGGGTGGGGCGGCAAACGTGCAGGACATCTATCCACTGGCACCGCTGCAAGAGGGGGTGTTGTATCAC
CATCTGATGGCGCGCCAGGGCGACCCCTATCTGCTGCAGGCACAGTTGGCCTTCGACGACAAACCGTGCCTGGACGCGTT
CGTCGCACTCCTGCAGCGCATGGTCGATCGACACGACATCCTGCGTACCAGTGTGGCCTGGGAGGACTTGGCTGCGCCGG
TGCAGATCGTCTGGCGACAGGCACGTGTAGTTTGCGATCCGGTGCAGTTGAACCCGGACGATGGAGATGTGCTGGAGCAA
CTGCAGGCGCGATTCGATCCATGCCAGTACCGTCTCGCTCTCACCCATGCACCCTTGCTGCAATTGCATTACGCGCAGGA
TCCGCACAATGGCAGGCTGGTGGCGTTACTGCTGTTCCATCACATCGTGCTGGATCACAGCGCACTGGCGGCGATTCGCG
AGGAAATGCAGCACCTGTCCGCAGTCGGTGACGCCGGCCTGCCAACGCCCACGCCCTACCGTACGTATGTGACCCAGGCG
CTGCGGGGCAAGACCCAGGAGGAGCACGAAACCTTCTTCAGGCAATGCCTGGGAGACATCGATACGCCAACGCTGGCTTT
CGACACAGAAGATACGCCCGGCCATCTGCAACCGCTGCAGCAGTCCGACGTACTGCTCGATCCCATGCTCGCCAGTCGGC
TTCGCCGGCAGGCGCGAGATCTGCATCTGAGCGTCGCAAGCCTCCATCACCTGGCCTGGGCGATGGTGCTGGGATCGGGC
GTGGGTCGCGATGATGTCGTCTTCGGCAGCGTCTTGCTCGGGCGCATGCAGGGCGGCCCCGCTGCCGATCGCGCCTTGGG
CATGTTCATCAATAGCCTGCCGATCCGGGTCAGACTCGACGCGCCTGCCGCGGCCGCCGCGCGGCGCACGCACGATGCCT
TGACGGCGCTGATGGCACACGAACATGCATCGCTGGCATTGGCGCAGCGCTGCAGCAGCATTCCCGCTTCGACGCCGCTG
TTCAACGCATTGCTCAATTATCGGCATAGTCCGCCGCTACCGGCAGACGCGACGACATCCGCTGCCTGGCATGGCGTGCA
TGCACTTGGCAGCAGCGAGCGCACCAATTATCCGCTGCTGCTGAGCGTGGATGATCTTGGAGACCAATTCGCGCTGAGCG
TGCAAACCCGTGCGGACATCGGTGCCGAACGCATGTGCGCTTTCATGCAACGCGCACTTGCGCAGTTGGTCGATGCGCTC
GAGCAGTGCTCGGACCTGCCGGTCGGTCAGCTGTGCGTGCTGCCTGCCGACGAACTCGGACAGCTGCTGGACACCTTCAA
CGCCACCGATCGCGACTATCCACATGCACAGACCGTGCATGCGCTGTTCGAGCAGCAGGCGGCACTGACGCCGGAGGCGC
CAGCCGTGATCGATGGAGCGCATCGGTGCAGTTATGCAGCGCTCAACCGCAAGGCCAATCAGCTTGCGCATTACCTGATC
GGCCTGGGAGTAGGGGCGGGCCAGTACGTGGGCATTCGCCTTCCACGTTCGCTGGAGTTGGTGGTCGCGCAATTGGCCAT
CAACAAATGTGCCGCAGCGTATCTGCCGCTGGATGTGCAGTCGCCAGACCAACGTTTGCAGCAGATTCTCGATGAAAGCG
CAGCGCGCTGGGTCGTCAGTCGTAGCGACCAGCCGCTTCCCGATGGTGCTGCACGATTGGACATGGATCTGCTCGACTTG
AGCGCATCGCCCACGCACGATCCGCAGTTGTCCCAGTCCAGCGCGTCGGACGCCTATGTGATGTACACCTCCGGCTCGAC
CGGTGTTCCTAAAGGCGTGCGGATCGCGCATCGGGGCATCAATCGGCTGGTGTGCAACAACGGCTATGCCAAGTTCCAGC
CCGGCGATCGGGTGGCCTTCGCTGCCAATCCGGCCTTCGACGCCAGTACCCTGGAAGTGTGGGCGCCGCTACTCACCGGC
GGCTGCGTAGTGGTGATTGCGCAGGACATCGTGCTGTCGCCAGACCGGCCGCGGGAGTGTTTGCAGAACCAGGCCGTCAA
CGTGCTGTGGCTGACGGCCGGGCTGTTCCATCACCACGCAGCCGTGTTGCTGCCGGCCATTGCGCAGCTGCGTTATCTGA
TCGTGGGCGGTGACGTCCTCGACCCGGCAGTGGTAGCGCGGGTGTTGGCCGAAGGGGCGCCGCAGAGGTTGCTCAACGGA
TACGGGCCGACCGAGACCACGACCTTCGCAACCATCCACTGCATCACCGAAGTCTCCGGCCCCATTCCGATTGGCCGCCC
CATCGGCAATACCCGTGTCTATGTGCTGGATGCGCATGGCACGCCGCTGCCGATCGGCGTGGCGGGCGAGTTGTACATCG
GCGGCGATGGTGTGGCGCTGGGATACCTGCATCAACCGACGCTGACCGCCGAGCGGTTTATTGCCGACCGCTTCAGCGGC
AAGGCGGATGCGCGCCTGTATCGCAGTGGCGATCTGGTGCGCTGGCGGGCGGACGGTGTGCTCGAATACCTGGGCCGCAC
CGATGGGCAGGTCAAAGTGTGCGGTTTCCGTGTTGAATTGGGAGAAATCGCGTCCGCGCTCCAAACGCATCCGGCGGTTG
CGATTGCGGCGGTTGTGCAGCGTGAAGATGTGCGGGGGTCGAAACAGCTGGTGGCTTACTACCAGGTAGACGTGGCAGCG
AACCTCGCTCACGATGCACAGGCGTTACGCATGCATCTGTTGACCCGCGTACCGGATTACATGCTGCCGTCTGCGTATGT
ACAGATGGAGCAATTGCCACTGACCGCCAACGGCAAGCTGGATCGGCATGCCTTGCCGCTGCCGGCACGCAATGATCATG
CTGGCCACGACGACACGCCGCCACAAGGCGAGCTGGAAACATTGCTCCATACGCTGTGGTCGCAGTTACTTCGCATCGAT
CGCATCGGGCGGCACGACGATTTCCTCGCACTGGGCGGTCATTCGCTGCTGCTGGTACGCCTCAATGGCCTGCTGAAGCG
GGCAGGGACGGCGGTGCCGTTATCTGTGCTGAGTGCGCATACCAGTCTGGCGGCGATGGCGACAGCGATCGAGCGGTGGC
GGGAGACCTCAACGCCACCGGGCGTGGTCACCGTGCGGATGGGCGGCGACAAGCGCCCGCTGTTTTTGGTACATGACTTC
AGCGGTCTGGATCTGTATTTTGCGCCCCTGGGCGAGCACCTTGCTCCGGATGTGCCGGTCTATGGGCTGTCCGCTGTTGC
GTTGGGCGCGCCCCAGCCACGTACCGTGCAGGAACTTGCGGCGCGTCTGTTACGTCATCTGCGCGCGGTGCAGCCGCACG
GACCTTACCGGGTTGCCGGCTGGTCATTCGGCGGGCTGTTGGCGTACGAGATTGCCACCCAATTGCTCGCTGTAGATGAG
CTGGTCGAGTTCGTTGGTTTGATCGATACCTATCATCCCTCGCAACTCGATCTCGGTCCAGCCTACATCGATCCTGCGCA
CGCGCCGCAGCGCCTCCTGCTGCAGCACTGCCTGGCCGCGCTGCCGGATGATGAGCAACGTGCCTCTGCCCAGGCCAACC
TGCAGGCACTCGCGGCGCAGGTTGGCCAGTGGGAAGACACGGCATTGATCAGACTGTGCCGCTCGCGCGGCTGGTTGCCG
TCCGCGTGGGCCGACCAGGACGACGCCAGCCTGCCGCAATCGCTGGCGCGCGAGTTCGCACACGGCTATGCACAGCGACA
CTACCTGCCGATGGCCATCCATATGCCGGTCCATCTGTTCGCTGCGGCGCAGGCCCTGGCGCCCCGGTCGGCCAGCGATG
CAGCGCTGGCATGGCAAGCGTTGCTTGGCGCAGACATGCTGACCTGCATCACCGTGCCAGGGGATGGTAATCCCCCCACT
TCTAGCGGTCGCCAGAAGTGGAGCTAA

Upstream 100 bases:

>100_bases
CGTGCTGCCGCCAGCAGAGCGCCAGCGTTTGCTGGGCTTCAACCTGCAGCATCGCGCGGCTGAGGCAGTGGATTCGTTGG
CGCCGTGACCAGGTATCACC

Downstream 100 bases:

>100_bases
GCGGCCATCGCCAACTTCATGGCAGGCGTGATGCCGCCGAGCGCCATATTCGGGCGCTCGTGGTTGTACGTCCATAGCCA
GCGGGTGGCTTTGTCCTGCA

Product: ATP-dependent serine activating enzyme

Products: pyrophosphate; AMP; enterobactin; pyrophosphate; L-Seryl-AMP [C]

Alternate protein names: Tyrocidine synthase III; ATP-dependent asparagine adenylase; AsnA; Asparagine activase; ATP-dependent glutamine adenylase; GlnA; Glutamine activase; ATP-dependent tyrosine adenylase; TyrA; Tyrosine activase; ATP-dependent valine adenylase; ValA; Valine activase; ATP-dependent ornithine adenylase; OrnA; Ornithine activase; ATP-dependent leucine adenylase; LeuA; Leucine activase [H]

Number of amino acids: Translated: 2008; Mature: 2008

Protein sequence:

>2008_residues
MLQTQGVNHYPVVLDVEEMDDGIRLTGYLPTGYSALRLCTYMRSALQQLADALEHERETPINQLCVLPPAERQRLLGFNL
QHRVPERMDTVHGLFERQVAATPEAVALECDGQRLQYRELDTRANQLAHRLLQLGIGPDERVAICVQRSAELIIGLLAIL
KAGAAYVPLDPTYPAERLAYLLHDSAPRAVLVHAPTRSALGAAALPLIDIDNAAAGELPCTNPQVPGLTAAHLAYVIYTS
GSSGQPKGVMVEHRQLAQLVAWHTAAFGVGEGTRSSSLAGLSFDAAAWEIWPSLCSGGVLVMPSAAHSADVASLLQWWRA
QELDVSFLPTPIAEHAFAAGMTPQRLRCLLVGGDRLRQVPEGLPFSVYNNYGPTETTVVASSGVVPPGVPNPSIGRPLPY
LRAYVLDAQGQLAPLGVVGELYLGGAGVARGYLGREALTAERFIGDPFYPGARMYRTGDLCRWLDDGRLDYVGRNDAQVK
IRGRRIELGEIQAHLLAHPQVREAVVLAREDVAGERRLVGYVIATAEAPTAAELQRHLRVHLPEYLVPEAFVPVDAWPLT
ANGKLDRHALPGPDAAQRNLQTYEPPANALEQQLAEIWQAVLGVERVGRHDNFFQLGGHSLLAVTLVERLRQQGLGMDVR
ALLGQPTLAATAAALGRSQELEVPPNLIPAGCARITPELLTLVELSQATIDRIVATVPGGAANVQDIYPLAPLQEGVLYH
HLMARQGDPYLLQAQLAFDDKPCLDAFVALLQRMVDRHDILRTSVAWEDLAAPVQIVWRQARVVCDPVQLNPDDGDVLEQ
LQARFDPCQYRLALTHAPLLQLHYAQDPHNGRLVALLLFHHIVLDHSALAAIREEMQHLSAVGDAGLPTPTPYRTYVTQA
LRGKTQEEHETFFRQCLGDIDTPTLAFDTEDTPGHLQPLQQSDVLLDPMLASRLRRQARDLHLSVASLHHLAWAMVLGSG
VGRDDVVFGSVLLGRMQGGPAADRALGMFINSLPIRVRLDAPAAAAARRTHDALTALMAHEHASLALAQRCSSIPASTPL
FNALLNYRHSPPLPADATTSAAWHGVHALGSSERTNYPLLLSVDDLGDQFALSVQTRADIGAERMCAFMQRALAQLVDAL
EQCSDLPVGQLCVLPADELGQLLDTFNATDRDYPHAQTVHALFEQQAALTPEAPAVIDGAHRCSYAALNRKANQLAHYLI
GLGVGAGQYVGIRLPRSLELVVAQLAINKCAAAYLPLDVQSPDQRLQQILDESAARWVVSRSDQPLPDGAARLDMDLLDL
SASPTHDPQLSQSSASDAYVMYTSGSTGVPKGVRIAHRGINRLVCNNGYAKFQPGDRVAFAANPAFDASTLEVWAPLLTG
GCVVVIAQDIVLSPDRPRECLQNQAVNVLWLTAGLFHHHAAVLLPAIAQLRYLIVGGDVLDPAVVARVLAEGAPQRLLNG
YGPTETTTFATIHCITEVSGPIPIGRPIGNTRVYVLDAHGTPLPIGVAGELYIGGDGVALGYLHQPTLTAERFIADRFSG
KADARLYRSGDLVRWRADGVLEYLGRTDGQVKVCGFRVELGEIASALQTHPAVAIAAVVQREDVRGSKQLVAYYQVDVAA
NLAHDAQALRMHLLTRVPDYMLPSAYVQMEQLPLTANGKLDRHALPLPARNDHAGHDDTPPQGELETLLHTLWSQLLRID
RIGRHDDFLALGGHSLLLVRLNGLLKRAGTAVPLSVLSAHTSLAAMATAIERWRETSTPPGVVTVRMGGDKRPLFLVHDF
SGLDLYFAPLGEHLAPDVPVYGLSAVALGAPQPRTVQELAARLLRHLRAVQPHGPYRVAGWSFGGLLAYEIATQLLAVDE
LVEFVGLIDTYHPSQLDLGPAYIDPAHAPQRLLLQHCLAALPDDEQRASAQANLQALAAQVGQWEDTALIRLCRSRGWLP
SAWADQDDASLPQSLAREFAHGYAQRHYLPMAIHMPVHLFAAAQALAPRSASDAALAWQALLGADMLTCITVPGDGNPPT
SSGRQKWS

Sequences:

>Translated_2008_residues
MLQTQGVNHYPVVLDVEEMDDGIRLTGYLPTGYSALRLCTYMRSALQQLADALEHERETPINQLCVLPPAERQRLLGFNL
QHRVPERMDTVHGLFERQVAATPEAVALECDGQRLQYRELDTRANQLAHRLLQLGIGPDERVAICVQRSAELIIGLLAIL
KAGAAYVPLDPTYPAERLAYLLHDSAPRAVLVHAPTRSALGAAALPLIDIDNAAAGELPCTNPQVPGLTAAHLAYVIYTS
GSSGQPKGVMVEHRQLAQLVAWHTAAFGVGEGTRSSSLAGLSFDAAAWEIWPSLCSGGVLVMPSAAHSADVASLLQWWRA
QELDVSFLPTPIAEHAFAAGMTPQRLRCLLVGGDRLRQVPEGLPFSVYNNYGPTETTVVASSGVVPPGVPNPSIGRPLPY
LRAYVLDAQGQLAPLGVVGELYLGGAGVARGYLGREALTAERFIGDPFYPGARMYRTGDLCRWLDDGRLDYVGRNDAQVK
IRGRRIELGEIQAHLLAHPQVREAVVLAREDVAGERRLVGYVIATAEAPTAAELQRHLRVHLPEYLVPEAFVPVDAWPLT
ANGKLDRHALPGPDAAQRNLQTYEPPANALEQQLAEIWQAVLGVERVGRHDNFFQLGGHSLLAVTLVERLRQQGLGMDVR
ALLGQPTLAATAAALGRSQELEVPPNLIPAGCARITPELLTLVELSQATIDRIVATVPGGAANVQDIYPLAPLQEGVLYH
HLMARQGDPYLLQAQLAFDDKPCLDAFVALLQRMVDRHDILRTSVAWEDLAAPVQIVWRQARVVCDPVQLNPDDGDVLEQ
LQARFDPCQYRLALTHAPLLQLHYAQDPHNGRLVALLLFHHIVLDHSALAAIREEMQHLSAVGDAGLPTPTPYRTYVTQA
LRGKTQEEHETFFRQCLGDIDTPTLAFDTEDTPGHLQPLQQSDVLLDPMLASRLRRQARDLHLSVASLHHLAWAMVLGSG
VGRDDVVFGSVLLGRMQGGPAADRALGMFINSLPIRVRLDAPAAAAARRTHDALTALMAHEHASLALAQRCSSIPASTPL
FNALLNYRHSPPLPADATTSAAWHGVHALGSSERTNYPLLLSVDDLGDQFALSVQTRADIGAERMCAFMQRALAQLVDAL
EQCSDLPVGQLCVLPADELGQLLDTFNATDRDYPHAQTVHALFEQQAALTPEAPAVIDGAHRCSYAALNRKANQLAHYLI
GLGVGAGQYVGIRLPRSLELVVAQLAINKCAAAYLPLDVQSPDQRLQQILDESAARWVVSRSDQPLPDGAARLDMDLLDL
SASPTHDPQLSQSSASDAYVMYTSGSTGVPKGVRIAHRGINRLVCNNGYAKFQPGDRVAFAANPAFDASTLEVWAPLLTG
GCVVVIAQDIVLSPDRPRECLQNQAVNVLWLTAGLFHHHAAVLLPAIAQLRYLIVGGDVLDPAVVARVLAEGAPQRLLNG
YGPTETTTFATIHCITEVSGPIPIGRPIGNTRVYVLDAHGTPLPIGVAGELYIGGDGVALGYLHQPTLTAERFIADRFSG
KADARLYRSGDLVRWRADGVLEYLGRTDGQVKVCGFRVELGEIASALQTHPAVAIAAVVQREDVRGSKQLVAYYQVDVAA
NLAHDAQALRMHLLTRVPDYMLPSAYVQMEQLPLTANGKLDRHALPLPARNDHAGHDDTPPQGELETLLHTLWSQLLRID
RIGRHDDFLALGGHSLLLVRLNGLLKRAGTAVPLSVLSAHTSLAAMATAIERWRETSTPPGVVTVRMGGDKRPLFLVHDF
SGLDLYFAPLGEHLAPDVPVYGLSAVALGAPQPRTVQELAARLLRHLRAVQPHGPYRVAGWSFGGLLAYEIATQLLAVDE
LVEFVGLIDTYHPSQLDLGPAYIDPAHAPQRLLLQHCLAALPDDEQRASAQANLQALAAQVGQWEDTALIRLCRSRGWLP
SAWADQDDASLPQSLAREFAHGYAQRHYLPMAIHMPVHLFAAAQALAPRSASDAALAWQALLGADMLTCITVPGDGNPPT
SSGRQKWS
>Mature_2008_residues
MLQTQGVNHYPVVLDVEEMDDGIRLTGYLPTGYSALRLCTYMRSALQQLADALEHERETPINQLCVLPPAERQRLLGFNL
QHRVPERMDTVHGLFERQVAATPEAVALECDGQRLQYRELDTRANQLAHRLLQLGIGPDERVAICVQRSAELIIGLLAIL
KAGAAYVPLDPTYPAERLAYLLHDSAPRAVLVHAPTRSALGAAALPLIDIDNAAAGELPCTNPQVPGLTAAHLAYVIYTS
GSSGQPKGVMVEHRQLAQLVAWHTAAFGVGEGTRSSSLAGLSFDAAAWEIWPSLCSGGVLVMPSAAHSADVASLLQWWRA
QELDVSFLPTPIAEHAFAAGMTPQRLRCLLVGGDRLRQVPEGLPFSVYNNYGPTETTVVASSGVVPPGVPNPSIGRPLPY
LRAYVLDAQGQLAPLGVVGELYLGGAGVARGYLGREALTAERFIGDPFYPGARMYRTGDLCRWLDDGRLDYVGRNDAQVK
IRGRRIELGEIQAHLLAHPQVREAVVLAREDVAGERRLVGYVIATAEAPTAAELQRHLRVHLPEYLVPEAFVPVDAWPLT
ANGKLDRHALPGPDAAQRNLQTYEPPANALEQQLAEIWQAVLGVERVGRHDNFFQLGGHSLLAVTLVERLRQQGLGMDVR
ALLGQPTLAATAAALGRSQELEVPPNLIPAGCARITPELLTLVELSQATIDRIVATVPGGAANVQDIYPLAPLQEGVLYH
HLMARQGDPYLLQAQLAFDDKPCLDAFVALLQRMVDRHDILRTSVAWEDLAAPVQIVWRQARVVCDPVQLNPDDGDVLEQ
LQARFDPCQYRLALTHAPLLQLHYAQDPHNGRLVALLLFHHIVLDHSALAAIREEMQHLSAVGDAGLPTPTPYRTYVTQA
LRGKTQEEHETFFRQCLGDIDTPTLAFDTEDTPGHLQPLQQSDVLLDPMLASRLRRQARDLHLSVASLHHLAWAMVLGSG
VGRDDVVFGSVLLGRMQGGPAADRALGMFINSLPIRVRLDAPAAAAARRTHDALTALMAHEHASLALAQRCSSIPASTPL
FNALLNYRHSPPLPADATTSAAWHGVHALGSSERTNYPLLLSVDDLGDQFALSVQTRADIGAERMCAFMQRALAQLVDAL
EQCSDLPVGQLCVLPADELGQLLDTFNATDRDYPHAQTVHALFEQQAALTPEAPAVIDGAHRCSYAALNRKANQLAHYLI
GLGVGAGQYVGIRLPRSLELVVAQLAINKCAAAYLPLDVQSPDQRLQQILDESAARWVVSRSDQPLPDGAARLDMDLLDL
SASPTHDPQLSQSSASDAYVMYTSGSTGVPKGVRIAHRGINRLVCNNGYAKFQPGDRVAFAANPAFDASTLEVWAPLLTG
GCVVVIAQDIVLSPDRPRECLQNQAVNVLWLTAGLFHHHAAVLLPAIAQLRYLIVGGDVLDPAVVARVLAEGAPQRLLNG
YGPTETTTFATIHCITEVSGPIPIGRPIGNTRVYVLDAHGTPLPIGVAGELYIGGDGVALGYLHQPTLTAERFIADRFSG
KADARLYRSGDLVRWRADGVLEYLGRTDGQVKVCGFRVELGEIASALQTHPAVAIAAVVQREDVRGSKQLVAYYQVDVAA
NLAHDAQALRMHLLTRVPDYMLPSAYVQMEQLPLTANGKLDRHALPLPARNDHAGHDDTPPQGELETLLHTLWSQLLRID
RIGRHDDFLALGGHSLLLVRLNGLLKRAGTAVPLSVLSAHTSLAAMATAIERWRETSTPPGVVTVRMGGDKRPLFLVHDF
SGLDLYFAPLGEHLAPDVPVYGLSAVALGAPQPRTVQELAARLLRHLRAVQPHGPYRVAGWSFGGLLAYEIATQLLAVDE
LVEFVGLIDTYHPSQLDLGPAYIDPAHAPQRLLLQHCLAALPDDEQRASAQANLQALAAQVGQWEDTALIRLCRSRGWLP
SAWADQDDASLPQSLAREFAHGYAQRHYLPMAIHMPVHLFAAAQALAPRSASDAALAWQALLGADMLTCITVPGDGNPPT
SSGRQKWS

Specific function: Incorporates six amino acids (for tyrocidine A, Asn, Gln, Tyr, Val, Orn, and Leu) in their L-configuration into the peptide product [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 6 acyl carrier domains [H]

Homologues:

Organism=Homo sapiens, GI45580730, Length=448, Percent_Identity=27.4553571428571, Blast_Score=116, Evalue=2e-25,
Organism=Homo sapiens, GI187761345, Length=564, Percent_Identity=26.241134751773, Blast_Score=102, Evalue=5e-21,
Organism=Homo sapiens, GI187761343, Length=564, Percent_Identity=26.241134751773, Blast_Score=102, Evalue=5e-21,
Organism=Homo sapiens, GI38505220, Length=505, Percent_Identity=23.5643564356436, Blast_Score=86, Evalue=5e-16,
Organism=Homo sapiens, GI115511026, Length=396, Percent_Identity=26.010101010101, Blast_Score=80, Evalue=2e-14,
Organism=Homo sapiens, GI122937307, Length=501, Percent_Identity=23.1536926147705, Blast_Score=78, Evalue=8e-14,
Organism=Homo sapiens, GI157311624, Length=503, Percent_Identity=23.0616302186879, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI157311622, Length=503, Percent_Identity=23.0616302186879, Blast_Score=74, Evalue=1e-12,
Organism=Homo sapiens, GI58082049, Length=503, Percent_Identity=22.8628230616302, Blast_Score=72, Evalue=7e-12,
Organism=Homo sapiens, GI156151445, Length=204, Percent_Identity=28.4313725490196, Blast_Score=70, Evalue=2e-11,
Organism=Escherichia coli, GI1786801, Length=945, Percent_Identity=33.4391534391534, Blast_Score=338, Evalue=2e-93,
Organism=Escherichia coli, GI145693145, Length=519, Percent_Identity=25.8188824662813, Blast_Score=112, Evalue=2e-25,
Organism=Escherichia coli, GI1786810, Length=521, Percent_Identity=28.0230326295585, Blast_Score=100, Evalue=2e-21,
Organism=Escherichia coli, GI1789201, Length=362, Percent_Identity=27.0718232044199, Blast_Score=88, Evalue=5e-18,
Organism=Escherichia coli, GI1790505, Length=538, Percent_Identity=24.1635687732342, Blast_Score=81, Evalue=7e-16,
Organism=Escherichia coli, GI1788107, Length=553, Percent_Identity=23.869801084991, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17556356, Length=568, Percent_Identity=26.4084507042254, Blast_Score=163, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI17550940, Length=677, Percent_Identity=22.7474150664697, Blast_Score=131, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI32564422, Length=426, Percent_Identity=22.3004694835681, Blast_Score=77, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32564420, Length=426, Percent_Identity=22.3004694835681, Blast_Score=77, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560308, Length=358, Percent_Identity=26.2569832402235, Blast_Score=76, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6319591, Length=698, Percent_Identity=25.9312320916905, Blast_Score=221, Evalue=1e-57,
Organism=Saccharomyces cerevisiae, GI6319699, Length=488, Percent_Identity=23.155737704918, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24648676, Length=697, Percent_Identity=29.2682926829268, Blast_Score=210, Evalue=7e-54,
Organism=Drosophila melanogaster, GI24581924, Length=533, Percent_Identity=24.577861163227, Blast_Score=93, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24582852, Length=367, Percent_Identity=23.1607629427793, Blast_Score=82, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19922652, Length=358, Percent_Identity=25.6983240223464, Blast_Score=70, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010071
- InterPro:   IPR009081
- InterPro:   IPR020845
- InterPro:   IPR000873
- InterPro:   IPR001242
- InterPro:   IPR006163
- InterPro:   IPR020806
- InterPro:   IPR006162
- InterPro:   IPR001031 [H]

Pfam domain/function: PF00501 AMP-binding; PF00668 Condensation; PF00550 PP-binding; PF00975 Thioesterase [H]

EC number: 2.7.7.- [C]

Molecular weight: Translated: 217506; Mature: 217506

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50075 ACP_DOMAIN ; PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTQGVNHYPVVLDVEEMDDGIRLTGYLPTGYSALRLCTYMRSALQQLADALEHERETP
CCCCCCCCCCCEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
INQLCVLPPAERQRLLGFNLQHRVPERMDTVHGLFERQVAATPEAVALECDGQRLQYREL
HHHEEECCCHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHH
DTRANQLAHRLLQLGIGPDERVAICVQRSAELIIGLLAILKAGAAYVPLDPTYPAERLAY
HHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHH
LLHDSAPRAVLVHAPTRSALGAAALPLIDIDNAAAGELPCTNPQVPGLTAAHLAYVIYTS
HHHCCCCCEEEEECCCCHHCCHHHCCEEECCCCCCCCCCCCCCCCCCCHHHEEEEEEEEC
GSSGQPKGVMVEHRQLAQLVAWHTAAFGVGEGTRSSSLAGLSFDAAAWEIWPSLCSGGVL
CCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEE
VMPSAAHSADVASLLQWWRAQELDVSFLPTPIAEHAFAAGMTPQRLRCLLVGGDRLRQVP
EECCCCCHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHCCCCHHHEEEEEECCHHHHHCC
EGLPFSVYNNYGPTETTVVASSGVVPPGVPNPSIGRPLPYLRAYVLDAQGQLAPLGVVGE
CCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEECCCHHHH
LYLGGAGVARGYLGREALTAERFIGDPFYPGARMYRTGDLCRWLDDGRLDYVGRNDAQVK
HHCCCCHHHHHHHCHHHHHHHHHCCCCCCCCCCEEECCCHHHHHCCCCEEECCCCCCEEE
IRGRRIELGEIQAHLLAHPQVREAVVLAREDVAGERRLVGYVIATAEAPTAAELQRHLRV
EECCEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHH
HLPEYLVPEAFVPVDAWPLTANGKLDRHALPGPDAAQRNLQTYEPPANALEQQLAEIWQA
CCCHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHH
VLGVERVGRHDNFFQLGGHSLLAVTLVERLRQQGLGMDVRALLGQPTLAATAAALGRSQE
HHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHCCCCC
LEVPPNLIPAGCARITPELLTLVELSQATIDRIVATVPGGAANVQDIYPLAPLQEGVLYH
CCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
HLMARQGDPYLLQAQLAFDDKPCLDAFVALLQRMVDRHDILRTSVAWEDLAAPVQIVWRQ
HHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARVVCDPVQLNPDDGDVLEQLQARFDPCQYRLALTHAPLLQLHYAQDPHNGRLVALLLFH
HHHEECCCEECCCCHHHHHHHHHHCCCHHEEEEECCCCCCEEEECCCCCCCCCHHHHHHH
HIVLDHSALAAIREEMQHLSAVGDAGLPTPTPYRTYVTQALRGKTQEEHETFFRQCLGDI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCC
DTPTLAFDTEDTPGHLQPLQQSDVLLDPMLASRLRRQARDLHLSVASLHHLAWAMVLGSG
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VGRDDVVFGSVLLGRMQGGPAADRALGMFINSLPIRVRLDAPAAAAARRTHDALTALMAH
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
EHASLALAQRCSSIPASTPLFNALLNYRHSPPLPADATTSAAWHGVHALGSSERTNYPLL
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEE
LSVDDLGDQFALSVQTRADIGAERMCAFMQRALAQLVDALEQCSDLPVGQLCVLPADELG
EEECCCCCCEEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHH
QLLDTFNATDRDYPHAQTVHALFEQQAALTPEAPAVIDGAHRCSYAALNRKANQLAHYLI
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHH
GLGVGAGQYVGIRLPRSLELVVAQLAINKCAAAYLPLDVQSPDQRLQQILDESAARWVVS
HHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
RSDQPLPDGAARLDMDLLDLSASPTHDPQLSQSSASDAYVMYTSGSTGVPKGVRIAHRGI
CCCCCCCCCHHHCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCC
NRLVCNNGYAKFQPGDRVAFAANPAFDASTLEVWAPLLTGGCVVVIAQDIVLSPDRPREC
HHEEECCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEHHHEECCCCHHHH
LQNQAVNVLWLTAGLFHHHAAVLLPAIAQLRYLIVGGDVLDPAVVARVLAEGAPQRLLNG
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCHHHHHCC
YGPTETTTFATIHCITEVSGPIPIGRPIGNTRVYVLDAHGTPLPIGVAGELYIGGDGVAL
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCEECCCEEEEECCCCEEE
GYLHQPTLTAERFIADRFSGKADARLYRSGDLVRWRADGVLEYLGRTDGQVKVCGFRVEL
EEEECCCHHHHHHHHHHHCCCCCCEEEECCCEEEEEHHHHHHHHCCCCCCEEEEEEEEEH
GEIASALQTHPAVAIAAVVQREDVRGSKQLVAYYQVDVAANLAHDAQALRMHLLTRVPDY
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCHH
MLPSAYVQMEQLPLTANGKLDRHALPLPARNDHAGHDDTPPQGELETLLHTLWSQLLRID
HCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RIGRHDDFLALGGHSLLLVRLNGLLKRAGTAVPLSVLSAHTSLAAMATAIERWRETSTPP
HCCCCCCEEEECCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GVVTVRMGGDKRPLFLVHDFSGLDLYFAPLGEHLAPDVPVYGLSAVALGAPQPRTVQELA
CEEEEEECCCCCCEEEEEECCCCEEEEECCCHHCCCCCCCCCCHHEEECCCCCHHHHHHH
ARLLRHLRAVQPHGPYRVAGWSFGGLLAYEIATQLLAVDELVEFVGLIDTYHPSQLDLGP
HHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AYIDPAHAPQRLLLQHCLAALPDDEQRASAQANLQALAAQVGQWEDTALIRLCRSRGWLP
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
SAWADQDDASLPQSLAREFAHGYAQRHYLPMAIHMPVHLFAAAQALAPRSASDAALAWQA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCCCHHHHHHHH
LLGADMLTCITVPGDGNPPTSSGRQKWS
HHCCCEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLQTQGVNHYPVVLDVEEMDDGIRLTGYLPTGYSALRLCTYMRSALQQLADALEHERETP
CCCCCCCCCCCEEEEHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
INQLCVLPPAERQRLLGFNLQHRVPERMDTVHGLFERQVAATPEAVALECDGQRLQYREL
HHHEEECCCHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHH
DTRANQLAHRLLQLGIGPDERVAICVQRSAELIIGLLAILKAGAAYVPLDPTYPAERLAY
HHHHHHHHHHHHHHCCCCCCCEEEEHHHHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHH
LLHDSAPRAVLVHAPTRSALGAAALPLIDIDNAAAGELPCTNPQVPGLTAAHLAYVIYTS
HHHCCCCCEEEEECCCCHHCCHHHCCEEECCCCCCCCCCCCCCCCCCCHHHEEEEEEEEC
GSSGQPKGVMVEHRQLAQLVAWHTAAFGVGEGTRSSSLAGLSFDAAAWEIWPSLCSGGVL
CCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEE
VMPSAAHSADVASLLQWWRAQELDVSFLPTPIAEHAFAAGMTPQRLRCLLVGGDRLRQVP
EECCCCCHHHHHHHHHHHCCCCCCCEECCCCHHHHHHHCCCCHHHEEEEEECCHHHHHCC
EGLPFSVYNNYGPTETTVVASSGVVPPGVPNPSIGRPLPYLRAYVLDAQGQLAPLGVVGE
CCCCEEEECCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCEECCCHHHH
LYLGGAGVARGYLGREALTAERFIGDPFYPGARMYRTGDLCRWLDDGRLDYVGRNDAQVK
HHCCCCHHHHHHHCHHHHHHHHHCCCCCCCCCCEEECCCHHHHHCCCCEEECCCCCCEEE
IRGRRIELGEIQAHLLAHPQVREAVVLAREDVAGERRLVGYVIATAEAPTAAELQRHLRV
EECCEEEHHHHHHHHHCCCHHHHHHHHHHHHCCCCCEEEEEEEEECCCCCHHHHHHHHHH
HLPEYLVPEAFVPVDAWPLTANGKLDRHALPGPDAAQRNLQTYEPPANALEQQLAEIWQA
CCCHHHCCCCCCCCCCEECCCCCCCCCCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHHHH
VLGVERVGRHDNFFQLGGHSLLAVTLVERLRQQGLGMDVRALLGQPTLAATAAALGRSQE
HHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHCCCCC
LEVPPNLIPAGCARITPELLTLVELSQATIDRIVATVPGGAANVQDIYPLAPLQEGVLYH
CCCCCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHH
HLMARQGDPYLLQAQLAFDDKPCLDAFVALLQRMVDRHDILRTSVAWEDLAAPVQIVWRQ
HHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARVVCDPVQLNPDDGDVLEQLQARFDPCQYRLALTHAPLLQLHYAQDPHNGRLVALLLFH
HHHEECCCEECCCCHHHHHHHHHHCCCHHEEEEECCCCCCEEEECCCCCCCCCHHHHHHH
HIVLDHSALAAIREEMQHLSAVGDAGLPTPTPYRTYVTQALRGKTQEEHETFFRQCLGDI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHCCC
DTPTLAFDTEDTPGHLQPLQQSDVLLDPMLASRLRRQARDLHLSVASLHHLAWAMVLGSG
CCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VGRDDVVFGSVLLGRMQGGPAADRALGMFINSLPIRVRLDAPAAAAARRTHDALTALMAH
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHH
EHASLALAQRCSSIPASTPLFNALLNYRHSPPLPADATTSAAWHGVHALGSSERTNYPLL
HHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCEE
LSVDDLGDQFALSVQTRADIGAERMCAFMQRALAQLVDALEQCSDLPVGQLCVLPADELG
EEECCCCCCEEEEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHH
QLLDTFNATDRDYPHAQTVHALFEQQAALTPEAPAVIDGAHRCSYAALNRKANQLAHYLI
HHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHHHHHHHHHHHH
GLGVGAGQYVGIRLPRSLELVVAQLAINKCAAAYLPLDVQSPDQRLQQILDESAARWVVS
HHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHC
RSDQPLPDGAARLDMDLLDLSASPTHDPQLSQSSASDAYVMYTSGSTGVPKGVRIAHRGI
CCCCCCCCCHHHCCHHHHCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCHHHHHHCC
NRLVCNNGYAKFQPGDRVAFAANPAFDASTLEVWAPLLTGGCVVVIAQDIVLSPDRPREC
HHEEECCCCEEECCCCEEEEECCCCCCCHHHHHHHHHHCCCEEEEEEHHHEECCCCHHHH
LQNQAVNVLWLTAGLFHHHAAVLLPAIAQLRYLIVGGDVLDPAVVARVLAEGAPQRLLNG
HHCCCCEEEEEHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHHHHHHHCCCHHHHHCC
YGPTETTTFATIHCITEVSGPIPIGRPIGNTRVYVLDAHGTPLPIGVAGELYIGGDGVAL
CCCCCCCCEEEEEEEECCCCCCCCCCCCCCCEEEEEECCCCCCEECCCEEEEECCCCEEE
GYLHQPTLTAERFIADRFSGKADARLYRSGDLVRWRADGVLEYLGRTDGQVKVCGFRVEL
EEEECCCHHHHHHHHHHHCCCCCCEEEECCCEEEEEHHHHHHHHCCCCCCEEEEEEEEEH
GEIASALQTHPAVAIAAVVQREDVRGSKQLVAYYQVDVAANLAHDAQALRMHLLTRVPDY
HHHHHHHHHCCHHHHHHHHHHHCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCHH
MLPSAYVQMEQLPLTANGKLDRHALPLPARNDHAGHDDTPPQGELETLLHTLWSQLLRID
HCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
RIGRHDDFLALGGHSLLLVRLNGLLKRAGTAVPLSVLSAHTSLAAMATAIERWRETSTPP
HCCCCCCEEEECCCEEEEHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
GVVTVRMGGDKRPLFLVHDFSGLDLYFAPLGEHLAPDVPVYGLSAVALGAPQPRTVQELA
CEEEEEECCCCCCEEEEEECCCCEEEEECCCHHCCCCCCCCCCHHEEECCCCCHHHHHHH
ARLLRHLRAVQPHGPYRVAGWSFGGLLAYEIATQLLAVDELVEFVGLIDTYHPSQLDLGP
HHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
AYIDPAHAPQRLLLQHCLAALPDDEQRASAQANLQALAAQVGQWEDTALIRLCRSRGWLP
CCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
SAWADQDDASLPQSLAREFAHGYAQRHYLPMAIHMPVHLFAAAQALAPRSASDAALAWQA
CCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHCCCCCCHHHHHHHH
LLGADMLTCITVPGDGNPPTSSGRQKWS
HHCCCEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Phosphopantetheine. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 6 ATP; L-serine; 2,3-dihydroxybenzoate [C]

Specific reaction: 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Seryl-AMP 6 ATP + 3 L-serine + 3 2,3-dihydroxybenzoate = 6 pyrophosphate + 6 AMP + enterobactin ATP + L-serine = pyrophosphate + L-Ser

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9352938; 10801488 [H]