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The map label for this gene is lolA

Identifier: 21242752

GI number: 21242752

Start: 2346431

End: 2347060

Strand: Direct

Name: lolA

Synonym: XAC2008

Alternate gene names: 21242752

Gene position: 2346431-2347060 (Clockwise)

Preceding gene: 21242751

Following gene: 161485713

Centisome position: 45.34

GC content: 64.29

Gene sequence:

>630_bases
ATGCATCGCCAGCTCCGTTATGCCGTCCTTGCCACTGCTCTGTTCGCCAGCACTGCGTTTGCCGGTGCGCGCCAGGAGCT
GGATACCTTCACGCGAGGGTTGAAGGGTCTGGATGGGCAGTTCAGTCAGCGCGTGACCGACGCGAATGGCCGGGTCAAGG
AGACCTCGAGCGGGCGGGTTGCACTGGCAACGCCGCGCCAGTTCCGTTGGGAATACGCCAAGCCCTACAAGCAGCTGATC
GTGGCCGATGGCAAGAAGGTCTGGGTATTCGACCCGGATCTGGAGCAGGTCACCGTGCGCGCACAGGGCAGCGAAGAACA
GAACAGCCCGCTGGTTGCGTTGATCGACCCGGCGCTTCTGGACAAGAAGTACGACGTCAGCGAAGAAGCCGCGCCACGCG
ACGGCCTGCAGTGGCTGTCGCTGACGCCCAAGGTAGACACCGACGCCAGCTTCCAGATCGCCTCGCTGGGGTTCGGCAGG
GAAGGCCTGGCCAGGATGGAAGTGGTAGACGCGGTCGGCCAGCGCACCGCGATCGGCTTTAGCGGCTGGAAGCGCAATCC
GGCGTTTGCTGCAGACACCTTCCGCTATACGCCGGCCAAGGGCGTGGATGTGGTGGGCGACGCGCAGTAA

Upstream 100 bases:

>100_bases
TTGCCGCGCACACGCTGCCATCTGAACACGTCGTGCGATAGCGCTCGCCCATTCATCTATGAAGTATCAGAATCTACGCA
TTCCCTTCTGGAAGACCGCG

Downstream 100 bases:

>100_bases
AAGCGTCTGCGGCACGCTCGGATGAAGGCATGGCGTAGCGAGCGGCGGCTGTGCCTGTGAGGGCCGCGGCAGTCGCTGTG
GCTCGACCGAGACGCCCTAC

Product: outer-membrane lipoprotein carrier protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 209; Mature: 209

Protein sequence:

>209_residues
MHRQLRYAVLATALFASTAFAGARQELDTFTRGLKGLDGQFSQRVTDANGRVKETSSGRVALATPRQFRWEYAKPYKQLI
VADGKKVWVFDPDLEQVTVRAQGSEEQNSPLVALIDPALLDKKYDVSEEAAPRDGLQWLSLTPKVDTDASFQIASLGFGR
EGLARMEVVDAVGQRTAIGFSGWKRNPAFAADTFRYTPAKGVDVVGDAQ

Sequences:

>Translated_209_residues
MHRQLRYAVLATALFASTAFAGARQELDTFTRGLKGLDGQFSQRVTDANGRVKETSSGRVALATPRQFRWEYAKPYKQLI
VADGKKVWVFDPDLEQVTVRAQGSEEQNSPLVALIDPALLDKKYDVSEEAAPRDGLQWLSLTPKVDTDASFQIASLGFGR
EGLARMEVVDAVGQRTAIGFSGWKRNPAFAADTFRYTPAKGVDVVGDAQ
>Mature_209_residues
MHRQLRYAVLATALFASTAFAGARQELDTFTRGLKGLDGQFSQRVTDANGRVKETSSGRVALATPRQFRWEYAKPYKQLI
VADGKKVWVFDPDLEQVTVRAQGSEEQNSPLVALIDPALLDKKYDVSEEAAPRDGLQWLSLTPKVDTDASFQIASLGFGR
EGLARMEVVDAVGQRTAIGFSGWKRNPAFAADTFRYTPAKGVDVVGDAQ

Specific function: Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the l

COG id: COG2834

COG function: function code M; Outer membrane lipoprotein-sorting protein

Gene ontology:

Cell location: Periplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lolA family

Homologues:

Organism=Escherichia coli, GI145693108, Length=199, Percent_Identity=25.1256281407035, Blast_Score=75, Evalue=2e-15,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): LOLA_XANAC (Q8PKZ8)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642334.1
- ProteinModelPortal:   Q8PKZ8
- SMR:   Q8PKZ8
- GeneID:   1156079
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2008
- NMPDR:   fig|190486.1.peg.1978
- HOGENOM:   HBG688940
- OMA:   MELRDAF
- ProtClustDB:   PRK00031
- BioCyc:   XAXO190486:XAC2008-MONOMER
- HAMAP:   MF_00240
- InterPro:   IPR004564
- InterPro:   IPR018323
- TIGRFAMs:   TIGR00547

Pfam domain/function: PF03548 LolA

EC number: NA

Molecular weight: Translated: 22956; Mature: 22956

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHRQLRYAVLATALFASTAFAGARQELDTFTRGLKGLDGQFSQRVTDANGRVKETSSGRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCEEECCCCEE
ALATPRQFRWEYAKPYKQLIVADGKKVWVFDPDLEQVTVRAQGSEEQNSPLVALIDPALL
EEECCHHHCCCHHHHHHHHEEECCCEEEEECCCHHEEEEEECCCCCCCCCEEEEECHHHH
DKKYDVSEEAAPRDGLQWLSLTPKVDTDASFQIASLGFGREGLARMEVVDAVGQRTAIGF
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEECC
SGWKRNPAFAADTFRYTPAKGVDVVGDAQ
CCCCCCCCCEECCEEECCCCCCCCCCCCC
>Mature Secondary Structure
MHRQLRYAVLATALFASTAFAGARQELDTFTRGLKGLDGQFSQRVTDANGRVKETSSGRV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHEECCCCCEEECCCCEE
ALATPRQFRWEYAKPYKQLIVADGKKVWVFDPDLEQVTVRAQGSEEQNSPLVALIDPALL
EEECCHHHCCCHHHHHHHHEEECCCEEEEECCCHHEEEEEECCCCCCCCCEEEEECHHHH
DKKYDVSEEAAPRDGLQWLSLTPKVDTDASFQIASLGFGREGLARMEVVDAVGQRTAIGF
CCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCEEECC
SGWKRNPAFAADTFRYTPAKGVDVVGDAQ
CCCCCCCCCEECCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217