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The map label for this gene is infA

Identifier: 21242746

GI number: 21242746

Start: 2338149

End: 2338367

Strand: Reverse

Name: infA

Synonym: XAC2002

Alternate gene names: 21242746

Gene position: 2338367-2338149 (Counterclockwise)

Preceding gene: 21242747

Following gene: 21242743

Centisome position: 45.18

GC content: 54.79

Gene sequence:

>219_bases
ATGTCGAAAGACGACTCCATTGAATTCGAAGGCAGCGTCAGCGAGACGCTTCCCAACACCACGTTCCGGGTCAAGCTGGA
GAACGGGCATGAAATCATCGCCCACATCTCCGGCCGTATGCGCAAGAACTACATCCGCATCCTGACCGGCGACCGGGTCA
AAGTTGAGATGACTCCCTACGACCTGACCAAGGGTCGTATTACCTACCGCATGAAGTAA

Upstream 100 bases:

>100_bases
GTGAAGCCCGCTTAACATAAAATTTGCACCACGGGGAGATGGCGCGTAAAATGCCGTCCCTTACGGCCCTGCCGGGCCAG
CCGTGATTGCACAGGATTAC

Downstream 100 bases:

>100_bases
GCGGTTCTGGTGCCGAGGCGCGAGGCGGCCATTGGCCGCTTTTTGTCGTGCCCATAATTCGAGCAGTGATGCGTTTCTAC
TGCCGGCAAGTTCCGCAGAG

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 72; Mature: 71

Protein sequence:

>72_residues
MSKDDSIEFEGSVSETLPNTTFRVKLENGHEIIAHISGRMRKNYIRILTGDRVKVEMTPYDLTKGRITYRMK

Sequences:

>Translated_72_residues
MSKDDSIEFEGSVSETLPNTTFRVKLENGHEIIAHISGRMRKNYIRILTGDRVKVEMTPYDLTKGRITYRMK
>Mature_71_residues
SKDDSIEFEGSVSETLPNTTFRVKLENGHEIIAHISGRMRKNYIRILTGDRVKVEMTPYDLTKGRITYRMK

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=70, Percent_Identity=72.8571428571428, Blast_Score=114, Evalue=8e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_XANAC (Q8PL04)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642328.1
- ProteinModelPortal:   Q8PL04
- SMR:   Q8PL04
- GeneID:   1156073
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2002
- HOGENOM:   HBG286099
- OMA:   KMRMHFI
- ProtClustDB:   PRK00276
- BioCyc:   XAXO190486:XAC2002-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 8376; Mature: 8245

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDDSIEFEGSVSETLPNTTFRVKLENGHEIIAHISGRMRKNYIRILTGDRVKVEMTPY
CCCCCCEEECCCCHHCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCEEEEEECCC
DLTKGRITYRMK
CCCCCEEEEEEC
>Mature Secondary Structure 
SKDDSIEFEGSVSETLPNTTFRVKLENGHEIIAHISGRMRKNYIRILTGDRVKVEMTPY
CCCCCEEECCCCHHCCCCCEEEEEECCCCEEEEEECCCCCCCEEEEEECCEEEEEECCC
DLTKGRITYRMK
CCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217