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The map label for this gene is aat

Identifier: 21242747

GI number: 21242747

Start: 2338448

End: 2339197

Strand: Reverse

Name: aat

Synonym: XAC2003

Alternate gene names: 21242747

Gene position: 2339197-2338448 (Counterclockwise)

Preceding gene: 21242748

Following gene: 21242746

Centisome position: 45.2

GC content: 66.27

Gene sequence:

>750_bases
ATGGCGCGCCATCTCCCCTTTCTGCTCGATGCCGATCCAACGGCACCGTTTCCGCCGGCCGCACAGGCCCTGCGCGACCC
GGACGGCCTGCTCGCCATCGGCGGCGACCTGGCGCCGCAGCGGCTGCTCAATGCCTATGCGCATGGCATTTTCCCGTGGT
TTTCGCAGGACCAGCCGATCCTGTGGTGGAGTCCGGACCCGCGCATGGTGTTTCGCACCGATGCGCTGCGCCTGTCGTCG
CGTTTCAGGCGTCAGCTACGCAGCAGCAGCTGGACCGTACGTGCCGACACCGCCTTCGAACAAGTCATCGACGCTTGCGC
GTCGGTTCCGCGCGCTGGCCAGGACGGCACCTGGATCACCGCACAGATGCAGCAGGCATACATCGCGTTGCACGAGCTGG
GCCATGCGCACTCACTGGAAGTGTTCGACGGCACGCGCCTGGTGGGCGGCATCTACGGCGTGGCGATCGGCCAGATGTTT
TTCGGCGAAAGCATGTTCAGCGCCCAAAGCGGCGGCTCCAAGGTGGCACTGGCCGCGCTAGCGATGCATCTGCACACCGA
AGGTTGGCCGCTGCTCGACGCGCAAGTGGAAAACCCGCACCTGCTCAGCCTGGGAGCGCAGCGCTTGCCGCGCGCGCAGT
TTCTGCAACAGGTACAGTTGCAGGTCGCCCGCCCCGCCCTGCCCGGCACGTGGTCCGGACGCTACGGACAACGCCCCGCC
AGCTCACTTGGTGAAGCCCGCTTAACATAA

Upstream 100 bases:

>100_bases
CGGTGCACGCCGATTCCGTGAAACGGTCGCAGACTCACCTTGCGGCAGGCTCGTGCCGCGGTCAGCGCAGTCGGCTTGCC
AGCTGCCCTACACTGCGCAG

Downstream 100 bases:

>100_bases
AATTTGCACCACGGGGAGATGGCGCGTAAAATGCCGTCCCTTACGGCCCTGCCGGGCCAGCCGTGATTGCACAGGATTAC
ATGTCGAAAGACGACTCCAT

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MARHLPFLLDADPTAPFPPAAQALRDPDGLLAIGGDLAPQRLLNAYAHGIFPWFSQDQPILWWSPDPRMVFRTDALRLSS
RFRRQLRSSSWTVRADTAFEQVIDACASVPRAGQDGTWITAQMQQAYIALHELGHAHSLEVFDGTRLVGGIYGVAIGQMF
FGESMFSAQSGGSKVALAALAMHLHTEGWPLLDAQVENPHLLSLGAQRLPRAQFLQQVQLQVARPALPGTWSGRYGQRPA
SSLGEARLT

Sequences:

>Translated_249_residues
MARHLPFLLDADPTAPFPPAAQALRDPDGLLAIGGDLAPQRLLNAYAHGIFPWFSQDQPILWWSPDPRMVFRTDALRLSS
RFRRQLRSSSWTVRADTAFEQVIDACASVPRAGQDGTWITAQMQQAYIALHELGHAHSLEVFDGTRLVGGIYGVAIGQMF
FGESMFSAQSGGSKVALAALAMHLHTEGWPLLDAQVENPHLLSLGAQRLPRAQFLQQVQLQVARPALPGTWSGRYGQRPA
SSLGEARLT
>Mature_248_residues
ARHLPFLLDADPTAPFPPAAQALRDPDGLLAIGGDLAPQRLLNAYAHGIFPWFSQDQPILWWSPDPRMVFRTDALRLSSR
FRRQLRSSSWTVRADTAFEQVIDACASVPRAGQDGTWITAQMQQAYIALHELGHAHSLEVFDGTRLVGGIYGVAIGQMFF
GESMFSAQSGGSKVALAALAMHLHTEGWPLLDAQVENPHLLSLGAQRLPRAQFLQQVQLQVARPALPGTWSGRYGQRPAS
SLGEARLT

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=209, Percent_Identity=50.2392344497608, Blast_Score=198, Evalue=3e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_XANAC (Q8PL03)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642329.1
- ProteinModelPortal:   Q8PL03
- SMR:   Q8PL03
- GeneID:   1156074
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC2003
- NMPDR:   fig|190486.1.peg.1973
- HOGENOM:   HBG485363
- OMA:   GEPILWW
- ProtClustDB:   PRK00301
- BioCyc:   XAXO190486:XAC2003-MONOMER
- BRENDA:   2.3.2.6
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 27301; Mature: 27170

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARHLPFLLDADPTAPFPPAAQALRDPDGLLAIGGDLAPQRLLNAYAHGIFPWFSQDQPI
CCCCCCEEEECCCCCCCCHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCE
LWWSPDPRMVFRTDALRLSSRFRRQLRSSSWTVRADTAFEQVIDACASVPRAGQDGTWIT
EEECCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEE
AQMQQAYIALHELGHAHSLEVFDGTRLVGGIYGVAIGQMFFGESMFSAQSGGSKVALAAL
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AMHLHTEGWPLLDAQVENPHLLSLGAQRLPRAQFLQQVQLQVARPALPGTWSGRYGQRPA
HHHHHCCCCCEEECCCCCCEEEHHCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
SSLGEARLT
HHCCCCCCC
>Mature Secondary Structure 
ARHLPFLLDADPTAPFPPAAQALRDPDGLLAIGGDLAPQRLLNAYAHGIFPWFSQDQPI
CCCCCEEEECCCCCCCCHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCCCCCE
LWWSPDPRMVFRTDALRLSSRFRRQLRSSSWTVRADTAFEQVIDACASVPRAGQDGTWIT
EEECCCCCEEEEHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCEEE
AQMQQAYIALHELGHAHSLEVFDGTRLVGGIYGVAIGQMFFGESMFSAQSGGSKVALAAL
HHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
AMHLHTEGWPLLDAQVENPHLLSLGAQRLPRAQFLQQVQLQVARPALPGTWSGRYGQRPA
HHHHHCCCCCEEECCCCCCEEEHHCHHHCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
SSLGEARLT
HHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217