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The map label for this gene is yciR [C]

Identifier: 21242736

GI number: 21242736

Start: 2323230

End: 2324951

Strand: Reverse

Name: yciR [C]

Synonym: XAC1992

Alternate gene names: 21242736

Gene position: 2324951-2323230 (Counterclockwise)

Preceding gene: 21242737

Following gene: 21242731

Centisome position: 44.92

GC content: 64.4

Gene sequence:

>1722_bases
ATGTGGAGCCCCGTAATCCCGCCCGGACTGGAAATCGTCAAGCCCACCCGGCTTGGCGCGGGCAGTCCCGAATTGCTGCA
CCTGGTGGATGCGGCCGCGTCCGGCGGTCCGCCGCTGATGATCTTCCACGTCGATATCGATCACTTCGCCTCGATCAACG
AGAACATGAGTGGCGAGGTCGGCGACCAGGCGCTGACGCTGGCAGCGCGCAGGCTGCAGGAATTTCTAGGCGCGCGCGGC
AAGCTGTGGCGCCACGGCAGCGATGAAATGGTGGTTGTGGCGGTGCGCCGCGACGACACGCCCTTGCCGGAAGATTTTGC
CGAGGAAATCCGCCAGCAACTGGAACTGCCGCTGTCGGTGCTGCCGTATACCTTGTTCATGACCGGCAAGGTCGGCATCA
GCCTGTGTCCGGAACATTCCACCTCCTTGTCCACGCTGCTGGATTACGCCGAAGAAGCCAGCTACCAGGCCGCGCGCGAA
GGCGGCAACACGGTGCGGCTGTACACGCGCAACTCGGCCACCAACGCGCATAGCGAAAGCATCATTGCGCGGCAGATCGT
CGATGCGATTCCGCACGGCGAATTGCGCCTGCGCTACCAACCGCTGGTGAGTGCGCGCGATGGCCGCATCGTGGGCATGG
AAGCGCTGCTGCGCTGGCAATCGCCCACCCTGGGCATGCTGGTGCCGGAGCGCTTCATGCGTACCGCCGAGCGCCTGGGC
GTGATCGTGCAGATCGGCGAATGGGTATTGCAGAACGCGGTGCGCCAGGCGCGGCTGTGGCGCGACCAGGGTTTCGACGA
TTTCAGCATCGCAGTGAATGTTTCCACGCTGCAGTTGCTGCGCCCGGGCTTCTTCAACGAAGTGATGGCGATGCTGCAGA
CTGCCGGTGTACCGGCGCAGTTCGTCACGCTGGAGATCAACGAAAGCGCGTTGACCAACAACGTCAACTTCGTCCACGAG
ACGATGGCCAACCTGCGCAACGAAGGCATCAGCCTGAGCCTGGACAACTTCGGCACCGGCGATTCCAGCCTGAGCGCGCT
GGTGCGCTACCCGGTGGACCGGCTCAAGATCGACCGCAGCTTCATCAAGAGCGCACCGGCCGGCAGCCGCGAGGCGGCGA
TCGCGCGCGCCATCATCGCCATGGGCCACCAGCTCGGCATGACGGTGATTGCCAATGGCGTGGAATCGCAGGCGCAGCTG
GGCTTTTTGCGCCGTAACGATTGCGACATCTTCCAGGGCTACCTGTTCGGCGAGCCGATGTCGGCCGAGTCGGCGGGCAT
GGCACTACGGCGGCGCTACCTGCGCCCGGAATCGTTCGCCGAGAGCCGCCCCGACCGCACGCTCTTGCTGCTGGACGACG
AAGAAAACGTGCTGCGCTCGCTGGTGCGCCTGTTCCGCCGCGACGGTTACCGGATTCTGGCGGCCGGCAACGTGCGCGAC
GCCTTCGACCTGCTGGCCACCAACGATGTACAGGTGATCCTGTCCGACCAGCGCATGAGCGACATGAGCGGCACCGAATT
CCTGGGACGGGTCAAGATGCTCTACCCCGACACGGTGCGCCTGGTGCTCTCCGGCTACACCGACCTGGCCACCGTCACCG
AGGCCATCAACCGCGGCGCGATCTACCGTTTCCTGACCAAACCCTGGAATGACGACGAACTGCGCGAGCATATTCGCCAG
GCGTTCCGCACGCATGATGAGTTGCGTAACGGCCGGGAATAG

Upstream 100 bases:

>100_bases
CGCGATAGAATCGGCTCCCGGAGCAGGCACGCGCGTGACGTTGCGCCTGCCCTATCACCCGGTCGGCGAGTCCGTCCACG
ACGATGGTGGACGTTGAGTC

Downstream 100 bases:

>100_bases
GGAATCGGGATTGGGGAATCGGTAGAGCAGACCTCTGCGTCTTGTTGCTTCTCAGACACGCAGCCAGATCAAGCGAGCGA
AAAGCTGCTTTACCGATTCC

Product: c-di-GMP phosphodiesterase A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 573; Mature: 573

Protein sequence:

>573_residues
MWSPVIPPGLEIVKPTRLGAGSPELLHLVDAAASGGPPLMIFHVDIDHFASINENMSGEVGDQALTLAARRLQEFLGARG
KLWRHGSDEMVVVAVRRDDTPLPEDFAEEIRQQLELPLSVLPYTLFMTGKVGISLCPEHSTSLSTLLDYAEEASYQAARE
GGNTVRLYTRNSATNAHSESIIARQIVDAIPHGELRLRYQPLVSARDGRIVGMEALLRWQSPTLGMLVPERFMRTAERLG
VIVQIGEWVLQNAVRQARLWRDQGFDDFSIAVNVSTLQLLRPGFFNEVMAMLQTAGVPAQFVTLEINESALTNNVNFVHE
TMANLRNEGISLSLDNFGTGDSSLSALVRYPVDRLKIDRSFIKSAPAGSREAAIARAIIAMGHQLGMTVIANGVESQAQL
GFLRRNDCDIFQGYLFGEPMSAESAGMALRRRYLRPESFAESRPDRTLLLLDDEENVLRSLVRLFRRDGYRILAAGNVRD
AFDLLATNDVQVILSDQRMSDMSGTEFLGRVKMLYPDTVRLVLSGYTDLATVTEAINRGAIYRFLTKPWNDDELREHIRQ
AFRTHDELRNGRE

Sequences:

>Translated_573_residues
MWSPVIPPGLEIVKPTRLGAGSPELLHLVDAAASGGPPLMIFHVDIDHFASINENMSGEVGDQALTLAARRLQEFLGARG
KLWRHGSDEMVVVAVRRDDTPLPEDFAEEIRQQLELPLSVLPYTLFMTGKVGISLCPEHSTSLSTLLDYAEEASYQAARE
GGNTVRLYTRNSATNAHSESIIARQIVDAIPHGELRLRYQPLVSARDGRIVGMEALLRWQSPTLGMLVPERFMRTAERLG
VIVQIGEWVLQNAVRQARLWRDQGFDDFSIAVNVSTLQLLRPGFFNEVMAMLQTAGVPAQFVTLEINESALTNNVNFVHE
TMANLRNEGISLSLDNFGTGDSSLSALVRYPVDRLKIDRSFIKSAPAGSREAAIARAIIAMGHQLGMTVIANGVESQAQL
GFLRRNDCDIFQGYLFGEPMSAESAGMALRRRYLRPESFAESRPDRTLLLLDDEENVLRSLVRLFRRDGYRILAAGNVRD
AFDLLATNDVQVILSDQRMSDMSGTEFLGRVKMLYPDTVRLVLSGYTDLATVTEAINRGAIYRFLTKPWNDDELREHIRQ
AFRTHDELRNGRE
>Mature_573_residues
MWSPVIPPGLEIVKPTRLGAGSPELLHLVDAAASGGPPLMIFHVDIDHFASINENMSGEVGDQALTLAARRLQEFLGARG
KLWRHGSDEMVVVAVRRDDTPLPEDFAEEIRQQLELPLSVLPYTLFMTGKVGISLCPEHSTSLSTLLDYAEEASYQAARE
GGNTVRLYTRNSATNAHSESIIARQIVDAIPHGELRLRYQPLVSARDGRIVGMEALLRWQSPTLGMLVPERFMRTAERLG
VIVQIGEWVLQNAVRQARLWRDQGFDDFSIAVNVSTLQLLRPGFFNEVMAMLQTAGVPAQFVTLEINESALTNNVNFVHE
TMANLRNEGISLSLDNFGTGDSSLSALVRYPVDRLKIDRSFIKSAPAGSREAAIARAIIAMGHQLGMTVIANGVESQAQL
GFLRRNDCDIFQGYLFGEPMSAESAGMALRRRYLRPESFAESRPDRTLLLLDDEENVLRSLVRLFRRDGYRILAAGNVRD
AFDLLATNDVQVILSDQRMSDMSGTEFLGRVKMLYPDTVRLVLSGYTDLATVTEAINRGAIYRFLTKPWNDDELREHIRQ
AFRTHDELRNGRE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=395, Percent_Identity=32.1518987341772, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87081921, Length=396, Percent_Identity=31.5656565656566, Blast_Score=204, Evalue=9e-54,
Organism=Escherichia coli, GI226510982, Length=281, Percent_Identity=29.5373665480427, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI87081980, Length=238, Percent_Identity=32.3529411764706, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI87081845, Length=261, Percent_Identity=30.6513409961686, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1787055, Length=257, Percent_Identity=31.9066147859922, Blast_Score=126, Evalue=4e-30,
Organism=Escherichia coli, GI1786507, Length=264, Percent_Identity=28.4090909090909, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=29.535864978903, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI1788502, Length=252, Percent_Identity=27.7777777777778, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI87081743, Length=236, Percent_Identity=28.3898305084746, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788849, Length=232, Percent_Identity=28.0172413793103, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082096, Length=243, Percent_Identity=25.9259259259259, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787410, Length=133, Percent_Identity=32.3308270676692, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 63937; Mature: 63937

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS50042 CNMP_BINDING_3 ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWSPVIPPGLEIVKPTRLGAGSPELLHLVDAAASGGPPLMIFHVDIDHFASINENMSGEV
CCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECHHHHHHCCCCCCCCC
GDQALTLAARRLQEFLGARGKLWRHGSDEMVVVAVRRDDTPLPEDFAEEIRQQLELPLSV
CHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHH
LPYTLFMTGKVGISLCPEHSTSLSTLLDYAEEASYQAAREGGNTVRLYTRNSATNAHSES
HCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
IIARQIVDAIPHGELRLRYQPLVSARDGRIVGMEALLRWQSPTLGMLVPERFMRTAERLG
HHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHHCC
VIVQIGEWVLQNAVRQARLWRDQGFDDFSIAVNVSTLQLLRPGFFNEVMAMLQTAGVPAQ
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHCCCCEE
FVTLEINESALTNNVNFVHETMANLRNEGISLSLDNFGTGDSSLSALVRYPVDRLKIDRS
EEEEEECCHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHH
FIKSAPAGSREAAIARAIIAMGHQLGMTVIANGVESQAQLGFLRRNDCDIFQGYLFGEPM
HHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHCCCCCHHHHHHCCCCCC
SAESAGMALRRRYLRPESFAESRPDRTLLLLDDEENVLRSLVRLFRRDGYRILAAGNVRD
CCHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHH
AFDLLATNDVQVILSDQRMSDMSGTEFLGRVKMLYPDTVRLVLSGYTDLATVTEAINRGA
HHHHHCCCCEEEEEECCHHCCCCCHHHHHHHHEECCHHHHHHHHCCHHHHHHHHHHCCCC
IYRFLTKPWNDDELREHIRQAFRTHDELRNGRE
EEHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MWSPVIPPGLEIVKPTRLGAGSPELLHLVDAAASGGPPLMIFHVDIDHFASINENMSGEV
CCCCCCCCCCCEECCCCCCCCCHHHHHHHHHHCCCCCEEEEEEECHHHHHHCCCCCCCCC
GDQALTLAARRLQEFLGARGKLWRHGSDEMVVVAVRRDDTPLPEDFAEEIRQQLELPLSV
CHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHHH
LPYTLFMTGKVGISLCPEHSTSLSTLLDYAEEASYQAAREGGNTVRLYTRNSATNAHSES
HCEEEEEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHH
IIARQIVDAIPHGELRLRYQPLVSARDGRIVGMEALLRWQSPTLGMLVPERFMRTAERLG
HHHHHHHHHCCCCCEEEEEECCCCCCCCCEEEHHHHHHCCCCCCCCCCHHHHHHHHHHCC
VIVQIGEWVLQNAVRQARLWRDQGFDDFSIAVNVSTLQLLRPGFFNEVMAMLQTAGVPAQ
CHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHCCCCEE
FVTLEINESALTNNVNFVHETMANLRNEGISLSLDNFGTGDSSLSALVRYPVDRLKIDRS
EEEEEECCHHHHCCHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHCCHHHHHHHHH
FIKSAPAGSREAAIARAIIAMGHQLGMTVIANGVESQAQLGFLRRNDCDIFQGYLFGEPM
HHHCCCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCHHHHHHHHCCCCCHHHHHHCCCCCC
SAESAGMALRRRYLRPESFAESRPDRTLLLLDDEENVLRSLVRLFRRDGYRILAAGNVRD
CCHHHHHHHHHHHCCCHHHHHCCCCCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCHH
AFDLLATNDVQVILSDQRMSDMSGTEFLGRVKMLYPDTVRLVLSGYTDLATVTEAINRGA
HHHHHCCCCEEEEEECCHHCCCCCHHHHHHHHEECCHHHHHHHHCCHHHHHHHHHHCCCC
IYRFLTKPWNDDELREHIRQAFRTHDELRNGRE
EEHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]