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The map label for this gene is nreB [H]

Identifier: 21242737

GI number: 21242737

Start: 2324955

End: 2327087

Strand: Reverse

Name: nreB [H]

Synonym: XAC1994

Alternate gene names: 21242737

Gene position: 2327087-2324955 (Counterclockwise)

Preceding gene: 21242739

Following gene: 21242736

Centisome position: 44.96

GC content: 66.53

Gene sequence:

>2133_bases
ATGGCCGCATCGCCAGCACTCAAGGTCGTCCGCGGATCCATGCAACAGCCCGTCGCCGCGCCCGCATTTTCGTCAGCCCC
CGTCTCCTGTCTTCGTCTCGCCGAGCGCCTGCACCAAGGCCTGTGGACCCTGACCGGCCTGTATCTGCTGGTTGGCGTGA
TCTGGCTGCTGCTGGGCAACCGGTTGCTCTACCTGGCCGGCGCCGCCATGCCGGAGCGCTGGTCTGATGCGAGCTTTCTG
GTGCTGTCCAGCATCGTCATCCACCTGGTGCTGCGCCGCTTCACGGGCTTGATCGTGGACGAGTACGCCCAGCTGGCGCA
GTCCGAGGCGTTGCTGCAAGCCAAGTTCATGGCACTGCCCAGCCCGGCCTTCATCTACGACCTGGCCACCATGCGCATCC
TCGACGCCAATCCGGCGGCGCTGGAATTCTTCGGCTGGGAACGCGACGAGTTCCTGCAGCAGACGCTGCAGGCGATCTGG
CCCAATGCCGATGGCGAGCGGCTGGAAGAGATCATTGCGCAGATCCGCAGCAAGGGAGATGCCACCTGCGTGTTGAACGA
AGACCTGATGACGCGCAGCGGCACGCGGCATGTCGAGGTGCGGAGCAACCAGCTGCATCTGGCCAGCGGCCCTGCCCGCC
TGGTCGTCACCGTTGACCGCAGCGAAGAGCGCCAGGCGCAAGATCTGCGCGACGAGGCACTCGAACGGCTGGAGGAGGCG
CAGAGCATCGCGCGGCTGGGCTCCTGGCAACTGGATCGCACGACCGGCCTGGGCCGCTATTCGCCAGCGGTCTACCGCCT
GCTGGGGCGCAGCGTACCGATGCATCGTCGCGAGCATCGGCTGGAAGAATTGCTGACCGCCTCCGACAGCGCGACCCAGG
CGCGCATCGAACGCATGATCGAAGACATGTGTACCGGTGGCCAGGTGCAGATCGATGTGCTGCTGCCGCTGACCGGTGGC
GATTCGCAACCGCGCACGGTGCATCTGCGCGCCGAAAGCGTGACCAGCCCCAGCGGCGTGCGCCATGTGCACGGCACCTT
GCAGGATGTGAGCGAACGCGAGCAATCGCGCCGGCTGCTGCGCGAACGCGAGGAGCAGTTTCGCGAACTGGTGCGCGTGC
TGCCCGACGGGGTGCTGATTCTCGCCGACGAGCATGTGATGTACGCCAACGCGGCCGGCTCGGCCCAGTTCGGCTTCCAG
GGCGAAACCATCCTGGGCGAACCGCTGCAGACCCTGGTGGGCGACAACGACCTGCCGGTGGTGCGCGACTACCTGCGCGC
AGGCAGCGATCGCAATGAGCCGGTCTCCAGCGCACGCGCGATGCGTCGTCGCGACGGCAGCACCTTCTACGCAGGTCTGT
CGGCCGGCGACATCCGCTATGGCGGACGCAGCTGCAAGTTGCTGGTGGTGCGCGATCTGGGCGAACCCGAGCGCATGCGC
GATGCCCTGGCCGAGAGCAATGTCGAGCTGCAGGCGATGGCCAAACGTCTGTTTTCGTTGCAGGAAGATGAGCGGCGCGC
CATCTCGCGCGACCTGCATGACGACATTGGGCAAGCGATCACCGCGATGAAGTTGTCCGCGCATGCGGCCCTGGATGAGC
CGGACGCGGACGCGCGCCGCGAGGACTTGCTGGAAGTGGTGTCGCTGGCCGATACCACGGTGACCAAGCTGCGCAATCTG
TCGATGCTGTTGCGCCCGCCACAACTCGATGCCCTGGGCCTGGAGGCAGCGCTGCGCTGGCAGGCGTCGATGCTGTTCCG
CGCCTCGCAAGTGCGGCTGGAGCTGGATATTCAGGCGCTCGACGAACGGCCGGGCAACGAGATCGAACAGGCCTGCTTCC
GGATCGCGCAGGAAAGCCTGACCAACGCGTTGCGGCACGCCTGCGCCGGCGAAGTGCACCTGCGTCTGCATTCGATCGAC
GGCGACAGTTTCCGCCTGGAAGTCAGCGATGACGGCGATGGCTTCGAGCCGGAGGGTCCGCGTGGGCTGGGGCTGATCGT
GATGCGTGAGCGTGCGCAAACCGTCGGCGGCACGCTCGCGATAGAATCGGCTCCCGGAGCAGGCACGCGCGTGACGTTGC
GCCTGCCCTATCACCCGGTCGGCGAGTCCGTCCACGACGATGGTGGACGTTGA

Upstream 100 bases:

>100_bases
CGACCCCGGCCTTCGGGGTCGCAATGGATAACGGCAGTGCCGGCGAATAGTTGAGCCACCTGTTGCGAGCTGGACCGAAC
CGGCCCGAGTTACGGCTAAG

Downstream 100 bases:

>100_bases
GTCATGTGGAGCCCCGTAATCCCGCCCGGACTGGAAATCGTCAAGCCCACCCGGCTTGGCGCGGGCAGTCCCGAATTGCT
GCACCTGGTGGATGCGGCCG

Product: HrpX-like protein

Products: NA

Alternate protein names: Nitrogen regulation protein B [H]

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MAASPALKVVRGSMQQPVAAPAFSSAPVSCLRLAERLHQGLWTLTGLYLLVGVIWLLLGNRLLYLAGAAMPERWSDASFL
VLSSIVIHLVLRRFTGLIVDEYAQLAQSEALLQAKFMALPSPAFIYDLATMRILDANPAALEFFGWERDEFLQQTLQAIW
PNADGERLEEIIAQIRSKGDATCVLNEDLMTRSGTRHVEVRSNQLHLASGPARLVVTVDRSEERQAQDLRDEALERLEEA
QSIARLGSWQLDRTTGLGRYSPAVYRLLGRSVPMHRREHRLEELLTASDSATQARIERMIEDMCTGGQVQIDVLLPLTGG
DSQPRTVHLRAESVTSPSGVRHVHGTLQDVSEREQSRRLLREREEQFRELVRVLPDGVLILADEHVMYANAAGSAQFGFQ
GETILGEPLQTLVGDNDLPVVRDYLRAGSDRNEPVSSARAMRRRDGSTFYAGLSAGDIRYGGRSCKLLVVRDLGEPERMR
DALAESNVELQAMAKRLFSLQEDERRAISRDLHDDIGQAITAMKLSAHAALDEPDADARREDLLEVVSLADTTVTKLRNL
SMLLRPPQLDALGLEAALRWQASMLFRASQVRLELDIQALDERPGNEIEQACFRIAQESLTNALRHACAGEVHLRLHSID
GDSFRLEVSDDGDGFEPEGPRGLGLIVMRERAQTVGGTLAIESAPGAGTRVTLRLPYHPVGESVHDDGGR

Sequences:

>Translated_710_residues
MAASPALKVVRGSMQQPVAAPAFSSAPVSCLRLAERLHQGLWTLTGLYLLVGVIWLLLGNRLLYLAGAAMPERWSDASFL
VLSSIVIHLVLRRFTGLIVDEYAQLAQSEALLQAKFMALPSPAFIYDLATMRILDANPAALEFFGWERDEFLQQTLQAIW
PNADGERLEEIIAQIRSKGDATCVLNEDLMTRSGTRHVEVRSNQLHLASGPARLVVTVDRSEERQAQDLRDEALERLEEA
QSIARLGSWQLDRTTGLGRYSPAVYRLLGRSVPMHRREHRLEELLTASDSATQARIERMIEDMCTGGQVQIDVLLPLTGG
DSQPRTVHLRAESVTSPSGVRHVHGTLQDVSEREQSRRLLREREEQFRELVRVLPDGVLILADEHVMYANAAGSAQFGFQ
GETILGEPLQTLVGDNDLPVVRDYLRAGSDRNEPVSSARAMRRRDGSTFYAGLSAGDIRYGGRSCKLLVVRDLGEPERMR
DALAESNVELQAMAKRLFSLQEDERRAISRDLHDDIGQAITAMKLSAHAALDEPDADARREDLLEVVSLADTTVTKLRNL
SMLLRPPQLDALGLEAALRWQASMLFRASQVRLELDIQALDERPGNEIEQACFRIAQESLTNALRHACAGEVHLRLHSID
GDSFRLEVSDDGDGFEPEGPRGLGLIVMRERAQTVGGTLAIESAPGAGTRVTLRLPYHPVGESVHDDGGR
>Mature_709_residues
AASPALKVVRGSMQQPVAAPAFSSAPVSCLRLAERLHQGLWTLTGLYLLVGVIWLLLGNRLLYLAGAAMPERWSDASFLV
LSSIVIHLVLRRFTGLIVDEYAQLAQSEALLQAKFMALPSPAFIYDLATMRILDANPAALEFFGWERDEFLQQTLQAIWP
NADGERLEEIIAQIRSKGDATCVLNEDLMTRSGTRHVEVRSNQLHLASGPARLVVTVDRSEERQAQDLRDEALERLEEAQ
SIARLGSWQLDRTTGLGRYSPAVYRLLGRSVPMHRREHRLEELLTASDSATQARIERMIEDMCTGGQVQIDVLLPLTGGD
SQPRTVHLRAESVTSPSGVRHVHGTLQDVSEREQSRRLLREREEQFRELVRVLPDGVLILADEHVMYANAAGSAQFGFQG
ETILGEPLQTLVGDNDLPVVRDYLRAGSDRNEPVSSARAMRRRDGSTFYAGLSAGDIRYGGRSCKLLVVRDLGEPERMRD
ALAESNVELQAMAKRLFSLQEDERRAISRDLHDDIGQAITAMKLSAHAALDEPDADARREDLLEVVSLADTTVTKLRNLS
MLLRPPQLDALGLEAALRWQASMLFRASQVRLELDIQALDERPGNEIEQACFRIAQESLTNALRHACAGEVHLRLHSIDG
DSFRLEVSDDGDGFEPEGPRGLGLIVMRERAQTVGGTLAIESAPGAGTRVTLRLPYHPVGESVHDDGGR

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxyg

COG id: COG4585

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI87082311, Length=219, Percent_Identity=37.4429223744292, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1788812, Length=199, Percent_Identity=29.1457286432161, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787474, Length=195, Percent_Identity=29.7435897435897, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR011712
- InterPro:   IPR005467
- InterPro:   IPR017203 [H]

Pfam domain/function: PF02518 HATPase_c; PF07730 HisKA_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 78582; Mature: 78451

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: PS50112 PAS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASPALKVVRGSMQQPVAAPAFSSAPVSCLRLAERLHQGLWTLTGLYLLVGVIWLLLGN
CCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RLLYLAGAAMPERWSDASFLVLSSIVIHLVLRRFTGLIVDEYAQLAQSEALLQAKFMALP
HHEEHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPAFIYDLATMRILDANPAALEFFGWERDEFLQQTLQAIWPNADGERLEEIIAQIRSKGD
CCHHHHHHHHHEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
ATCVLNEDLMTRSGTRHVEVRSNQLHLASGPARLVVTVDRSEERQAQDLRDEALERLEEA
EEEEECCHHHHCCCCEEEEEECCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
QSIARLGSWQLDRTTGLGRYSPAVYRLLGRSVPMHRREHRLEELLTASDSATQARIERMI
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
EDMCTGGQVQIDVLLPLTGGDSQPRTVHLRAESVTSPSGVRHVHGTLQDVSEREQSRRLL
HHHCCCCEEEEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
REREEQFRELVRVLPDGVLILADEHVMYANAAGSAQFGFQGETILGEPLQTLVGDNDLPV
HHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCCCHH
VRDYLRAGSDRNEPVSSARAMRRRDGSTFYAGLSAGDIRYGGRSCKLLVVRDLGEPERMR
HHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCEEECCCCEEEEEEECCCCHHHHH
DALAESNVELQAMAKRLFSLQEDERRAISRDLHDDIGQAITAMKLSAHAALDEPDADARR
HHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
EDLLEVVSLADTTVTKLRNLSMLLRPPQLDALGLEAALRWQASMLFRASQVRLELDIQAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEHHHH
DERPGNEIEQACFRIAQESLTNALRHACAGEVHLRLHSIDGDSFRLEVSDDGDGFEPEGP
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCC
RGLGLIVMRERAQTVGGTLAIESAPGAGTRVTLRLPYHPVGESVHDDGGR
CCCEEEEEEHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure 
AASPALKVVRGSMQQPVAAPAFSSAPVSCLRLAERLHQGLWTLTGLYLLVGVIWLLLGN
CCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RLLYLAGAAMPERWSDASFLVLSSIVIHLVLRRFTGLIVDEYAQLAQSEALLQAKFMALP
HHEEHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SPAFIYDLATMRILDANPAALEFFGWERDEFLQQTLQAIWPNADGERLEEIIAQIRSKGD
CCHHHHHHHHHEEECCCCCEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCC
ATCVLNEDLMTRSGTRHVEVRSNQLHLASGPARLVVTVDRSEERQAQDLRDEALERLEEA
EEEEECCHHHHCCCCEEEEEECCEEEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHH
QSIARLGSWQLDRTTGLGRYSPAVYRLLGRSVPMHRREHRLEELLTASDSATQARIERMI
HHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
EDMCTGGQVQIDVLLPLTGGDSQPRTVHLRAESVTSPSGVRHVHGTLQDVSEREQSRRLL
HHHCCCCEEEEEEEEEECCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHH
REREEQFRELVRVLPDGVLILADEHVMYANAAGSAQFGFQGETILGEPLQTLVGDNDLPV
HHHHHHHHHHHHHCCCCEEEEECCEEEEECCCCCCCCCCCCCCCCCCHHHHHHCCCCCHH
VRDYLRAGSDRNEPVSSARAMRRRDGSTFYAGLSAGDIRYGGRSCKLLVVRDLGEPERMR
HHHHHHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCEEECCCCEEEEEEECCCCHHHHH
DALAESNVELQAMAKRLFSLQEDERRAISRDLHDDIGQAITAMKLSAHAALDEPDADARR
HHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
EDLLEVVSLADTTVTKLRNLSMLLRPPQLDALGLEAALRWQASMLFRASQVRLELDIQAL
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEHHHH
DERPGNEIEQACFRIAQESLTNALRHACAGEVHLRLHSIDGDSFRLEVSDDGDGFEPEGP
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEECCCCEEEEEECCCCCCCCCCCC
RGLGLIVMRERAQTVGGTLAIESAPGAGTRVTLRLPYHPVGESVHDDGGR
CCCEEEEEEHHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA