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The map label for this gene is nreC [H]

Identifier: 21242714

GI number: 21242714

Start: 2302086

End: 2302718

Strand: Reverse

Name: nreC [H]

Synonym: XAC1970

Alternate gene names: 21242714

Gene position: 2302718-2302086 (Counterclockwise)

Preceding gene: 21242715

Following gene: 21242713

Centisome position: 44.49

GC content: 66.03

Gene sequence:

>633_bases
GTGCGAGTCATCATCGTCGACGATCACACCCTTGTCCGTGCCGGCCTGTCCAGGCTGCTGCAAACCTTCGCCGGCATCGA
TGTCGTGGGCGAAGCCAGCAACGCGCAACAAGCCCTGGACATGACGTCCCTGCACCGGCCCGATCTGGTGCTGATGGACC
TGTCTTTGCCCGGCCGCAGCGGCCTGGATGCCATGACCGACGTGCTGCGCGCCGCGCCGCGTACGCATGTGGTGATGATG
TCCATGCACGACGACCCGGTGCATGTGCGCGACGCGCTCGATCGCGGCGCCGTCGGCTTCGTGGTCAAGGACGCCGCGCC
ACTGGAACTAGAGCTGGCGTTGCGCGCTGCCGCCGCTGGCCAGGTGTTCCTGAGCCCGCAGATCTCGTCCAAGATGATTG
CGCCGATGCTGGGCCGCGAGAAGCCGGTCGGCATTGCCGCACTGTCGCCGCGTCAGCGCGAGATCCTGCGTGAAATCGGC
CGCGGCCAGAGCAACAAGGAAATCGCGGCCGATTTGGGCATCAGCGTCAAGACCGTGGAAACCCACCGCGCCCGCATGAT
GGAGTCGCTCGGGTGCCGGCGCGCCAACGACTTGGTGCTCCTGGCCGCCAAACATCACAACGAGTTGGTCTGA

Upstream 100 bases:

>100_bases
GTCAGATCGCCGACGCCCGCCGCCAGCGTTGATCCGATGGTTGGCGCGGGGCGCCGGGTCGGCTAAGGTGCCCTTTACTG
AAAAAGGTCTCTTCTGCGCC

Downstream 100 bases:

>100_bases
CGCTCCCGCCGGGCACGCGTGGGCCAGCGACGGTTAAAACAGTGACGGGATTCCGGCGGGCATGCTTGAGCCCGCCGGAA
ACGTCGGGAAGTTCCCGACA

Product: response regulator

Products: NA

Alternate protein names: Nitrogen regulation protein C [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MRVIIVDDHTLVRAGLSRLLQTFAGIDVVGEASNAQQALDMTSLHRPDLVLMDLSLPGRSGLDAMTDVLRAAPRTHVVMM
SMHDDPVHVRDALDRGAVGFVVKDAAPLELELALRAAAAGQVFLSPQISSKMIAPMLGREKPVGIAALSPRQREILREIG
RGQSNKEIAADLGISVKTVETHRARMMESLGCRRANDLVLLAAKHHNELV

Sequences:

>Translated_210_residues
MRVIIVDDHTLVRAGLSRLLQTFAGIDVVGEASNAQQALDMTSLHRPDLVLMDLSLPGRSGLDAMTDVLRAAPRTHVVMM
SMHDDPVHVRDALDRGAVGFVVKDAAPLELELALRAAAAGQVFLSPQISSKMIAPMLGREKPVGIAALSPRQREILREIG
RGQSNKEIAADLGISVKTVETHRARMMESLGCRRANDLVLLAAKHHNELV
>Mature_210_residues
MRVIIVDDHTLVRAGLSRLLQTFAGIDVVGEASNAQQALDMTSLHRPDLVLMDLSLPGRSGLDAMTDVLRAAPRTHVVMM
SMHDDPVHVRDALDRGAVGFVVKDAAPLELELALRAAAAGQVFLSPQISSKMIAPMLGREKPVGIAALSPRQREILREIG
RGQSNKEIAADLGISVKTVETHRARMMESLGCRRANDLVLLAAKHHNELV

Specific function: Member of the two-component regulatory system nreB/nreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. Phosphorylated nreC binds to a GC-rich palindromic sequence at the promoters of the nitrate (narGHJI) and nit

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=36.231884057971, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI1790102, Length=200, Percent_Identity=35.5, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1788521, Length=195, Percent_Identity=33.8461538461538, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787473, Length=184, Percent_Identity=36.4130434782609, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788712, Length=205, Percent_Identity=27.3170731707317, Blast_Score=94, Evalue=8e-21,
Organism=Escherichia coli, GI1788546, Length=204, Percent_Identity=30.3921568627451, Blast_Score=89, Evalue=1e-19,
Organism=Escherichia coli, GI1786747, Length=197, Percent_Identity=27.9187817258883, Blast_Score=81, Evalue=4e-17,
Organism=Escherichia coli, GI87082052, Length=124, Percent_Identity=33.8709677419355, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22741; Mature: 22741

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
5.2 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
5.2 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVIIVDDHTLVRAGLSRLLQTFAGIDVVGEASNAQQALDMTSLHRPDLVLMDLSLPGRS
CEEEEECCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCC
GLDAMTDVLRAAPRTHVVMMSMHDDPVHVRDALDRGAVGFVVKDAAPLELELALRAAAAG
CHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCC
QVFLSPQISSKMIAPMLGREKPVGIAALSPRQREILREIGRGQSNKEIAADLGISVKTVE
EEEECCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCCCHHHHHCCCEEEEHH
THRARMMESLGCRRANDLVLLAAKHHNELV
HHHHHHHHHHCCCCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MRVIIVDDHTLVRAGLSRLLQTFAGIDVVGEASNAQQALDMTSLHRPDLVLMDLSLPGRS
CEEEEECCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHCCCCCEEEEEECCCCCC
GLDAMTDVLRAAPRTHVVMMSMHDDPVHVRDALDRGAVGFVVKDAAPLELELALRAAAAG
CHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHCCC
QVFLSPQISSKMIAPMLGREKPVGIAALSPRQREILREIGRGQSNKEIAADLGISVKTVE
EEEECCCHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCCCHHHHHCCCEEEEHH
THRARMMESLGCRRANDLVLLAAKHHNELV
HHHHHHHHHHCCCCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA