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The map label for this gene is tsr [H]

Identifier: 21242636

GI number: 21242636

Start: 2200667

End: 2202631

Strand: Reverse

Name: tsr [H]

Synonym: XAC1892

Alternate gene names: 21242636

Gene position: 2202631-2200667 (Counterclockwise)

Preceding gene: 21242637

Following gene: 77748616

Centisome position: 42.56

GC content: 65.29

Gene sequence:

>1965_bases
GTGGTCTCCACGCTGATCTACAGCCCCGAGACCACCGAATCGCTGACCCGTCTGGACGCCGCCAGCGACCCCTCGCAGGC
GGGCGACAGCCGCGCCATGCTGCGCGAGCAGCTCGATCAACTTGCCCGAAACCATGTGCGTTTCCGCCATGAGCTGGACA
AGGCGATGGGCCTGCTGGAGCAGCCCGACCCTGCCCTGGCCGATGCCGCCAAGGTCGAAGCCACCCAGTCACGCGCCGCA
CTGGCCGCACTGGGTACCGCCTTGGAGGGCAGCGATGCCAAGGCCGACGCGCAGTGGAATGCCGCACTCGATGCGCTTGG
CCAGAGCATGCGGGACCTCAGCAACGTGTCCCTGCAGGCGCTGCAGCGGCAATCCGAGCGCCACCTGGTCGACGCACGCA
ACGCGATGTGGCAAGCGATCGCCGGCCTGTCGGTGCTGGCGCTGCTGATCGCCGCCCTGTGCTGGTATACCTTGTCGCGC
CTGACCCGCAATGTGCGCCGCGCCGCGACGGTGGCAGCCAATATCGCGCAGGGCCAGCTGGACGATCAGGTCAGTGCCGC
CGGCCGCGACGAAACCGGTCAATTGCTCGACACCATGCGCCAGATGCAAGGGCAACTGCAGCGCGTCCTCAGCGCGCAAA
GCGAAATGGCGCAGCGCCACGACGCCGGCCAGATCAGCTACCGCATGCAGGCAGACAGTTTCCCCGGTGCCTACGCCACC
ATGGTGCGCGACACCAACGCGCTGGTGGGCTCGCACATTGCAGTCAAGATGAAACTTGCGCAGATCATGTCGCGCTACGC
CATCGGCGACCTGAGCCAGGACATGGAGCGCCTGCCTGGCGAAAAGGCGGTGTTCACCGACACCATGGATACCGTCAAGG
CCAACCTGTCGGCGATGAACAGCGAGATCAAGCTGCTTGCGCAGGCCGCAGCCAATGGCGATTTCAGCGTGCGCGGCGAC
GCACAGCGCTTCCAGTACGACTTCCGCGCGATGGTGGACAGCCTCAATCAATTGATGGCCACCTCCGATGCGAATCTGCA
CGCGCTCTCGACGGTATTGCAGGCGATCGCGGCGGGCGACCTCACCGCCCGCATGCACGGCGACTTCCACGGCGTGTTCG
CGCGCATGCGCGACGATGCCAATACTACCGTGACCCAGCTGGCCAATATCGTCGGGCGCATCCAGCAGTCCACCAATGCC
ATCAACGACGCCGCCAGCGAAATTGCCACCGGCAATCAGGATTTGTCGCAACGCACCGAACAGCAAGCGGCCAATCTGGA
AGAAACCGCTGCCTCGATGGAAGAACTCACCTCCACCGTGCGCAACAACGCCGAGCATGCGCGCCGCGCAAACCAGTTGG
TGGTCGGTGCGGCCACGGTCGCCTCGCAAGGCGGTGCGGTAGTGGGTGAGGTCGTTGGCACCATGGCCGGCATCCAGGCT
GCATCCAAGAAGATCGCCGACATCATCAGCGTGATCGACGGCATCGCCTTCCAGACCAATATCCTGGCCTTGAACGCCGC
GGTGGAAGCGGCGCGCGCCGGCGAACAGGGCCGCGGCTTTGCAGTCGTGGCCAGCGAAGTGCGCACGCTGGCGCAGCGCT
CGGCCGGTGCGGCAAAAGAGATCAAGCAACTGATCGAGGACTCGGTCAGCCGGGTCGAACACGGCAACCAGTTGGTGGGC
CAGGCCGGTCGCACCATGCAGGACATCGTCGACTCGGTGCAGAACGTCACCACCATCATGCATGAGATCAGCGAGGCCTC
GCAGCAGCAGTCGCAAGGCATCGAACAGGTCGGCCAGACCATCGCGCAGATGGATCAGGCCACCCAGCAGAACGCCGCAC
TGGTGGAAGAAGCCACCGCCGCCGCCCGTTCGATGGAAGAACAGGCGCAGCAATTGCGCGATGCGGTCTCTGTGTTCCAG
TTGCAGGCTGGGCCTGCGCGTCGCCGCCTGGGCCACGCTGCCTAG

Upstream 100 bases:

>100_bases
AGGCTACGCCGCCGTGAGCGAACAGGCCTTTGCCGCGCTCGATGCATTACGCGACGACAGCCAGCTGGTCTACACCCCGT
ACATCGAGAGCTATCACCTG

Downstream 100 bases:

>100_bases
AGCGACCGGCGGTCGATCTGCCCTGGGACGCTGCGCGCACGCATGCGTCCCACCTTAGTGACTGCCCGCTGCCCGCATCG
ATCAGGCAACGGCGCAACTC

Product: chemotaxis protein

Products: NA

Alternate protein names: Citrate chemoreceptor protein [H]

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MVSTLIYSPETTESLTRLDAASDPSQAGDSRAMLREQLDQLARNHVRFRHELDKAMGLLEQPDPALADAAKVEATQSRAA
LAALGTALEGSDAKADAQWNAALDALGQSMRDLSNVSLQALQRQSERHLVDARNAMWQAIAGLSVLALLIAALCWYTLSR
LTRNVRRAATVAANIAQGQLDDQVSAAGRDETGQLLDTMRQMQGQLQRVLSAQSEMAQRHDAGQISYRMQADSFPGAYAT
MVRDTNALVGSHIAVKMKLAQIMSRYAIGDLSQDMERLPGEKAVFTDTMDTVKANLSAMNSEIKLLAQAAANGDFSVRGD
AQRFQYDFRAMVDSLNQLMATSDANLHALSTVLQAIAAGDLTARMHGDFHGVFARMRDDANTTVTQLANIVGRIQQSTNA
INDAASEIATGNQDLSQRTEQQAANLEETAASMEELTSTVRNNAEHARRANQLVVGAATVASQGGAVVGEVVGTMAGIQA
ASKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLAQRSAGAAKEIKQLIEDSVSRVEHGNQLVG
QAGRTMQDIVDSVQNVTTIMHEISEASQQQSQGIEQVGQTIAQMDQATQQNAALVEEATAAARSMEEQAQQLRDAVSVFQ
LQAGPARRRLGHAA

Sequences:

>Translated_654_residues
MVSTLIYSPETTESLTRLDAASDPSQAGDSRAMLREQLDQLARNHVRFRHELDKAMGLLEQPDPALADAAKVEATQSRAA
LAALGTALEGSDAKADAQWNAALDALGQSMRDLSNVSLQALQRQSERHLVDARNAMWQAIAGLSVLALLIAALCWYTLSR
LTRNVRRAATVAANIAQGQLDDQVSAAGRDETGQLLDTMRQMQGQLQRVLSAQSEMAQRHDAGQISYRMQADSFPGAYAT
MVRDTNALVGSHIAVKMKLAQIMSRYAIGDLSQDMERLPGEKAVFTDTMDTVKANLSAMNSEIKLLAQAAANGDFSVRGD
AQRFQYDFRAMVDSLNQLMATSDANLHALSTVLQAIAAGDLTARMHGDFHGVFARMRDDANTTVTQLANIVGRIQQSTNA
INDAASEIATGNQDLSQRTEQQAANLEETAASMEELTSTVRNNAEHARRANQLVVGAATVASQGGAVVGEVVGTMAGIQA
ASKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLAQRSAGAAKEIKQLIEDSVSRVEHGNQLVG
QAGRTMQDIVDSVQNVTTIMHEISEASQQQSQGIEQVGQTIAQMDQATQQNAALVEEATAAARSMEEQAQQLRDAVSVFQ
LQAGPARRRLGHAA
>Mature_654_residues
MVSTLIYSPETTESLTRLDAASDPSQAGDSRAMLREQLDQLARNHVRFRHELDKAMGLLEQPDPALADAAKVEATQSRAA
LAALGTALEGSDAKADAQWNAALDALGQSMRDLSNVSLQALQRQSERHLVDARNAMWQAIAGLSVLALLIAALCWYTLSR
LTRNVRRAATVAANIAQGQLDDQVSAAGRDETGQLLDTMRQMQGQLQRVLSAQSEMAQRHDAGQISYRMQADSFPGAYAT
MVRDTNALVGSHIAVKMKLAQIMSRYAIGDLSQDMERLPGEKAVFTDTMDTVKANLSAMNSEIKLLAQAAANGDFSVRGD
AQRFQYDFRAMVDSLNQLMATSDANLHALSTVLQAIAAGDLTARMHGDFHGVFARMRDDANTTVTQLANIVGRIQQSTNA
INDAASEIATGNQDLSQRTEQQAANLEETAASMEELTSTVRNNAEHARRANQLVVGAATVASQGGAVVGEVVGTMAGIQA
ASKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLAQRSAGAAKEIKQLIEDSVSRVEHGNQLVG
QAGRTMQDIVDSVQNVTTIMHEISEASQQQSQGIEQVGQTIAQMDQATQQNAALVEEATAAARSMEEQAQQLRDAVSVFQ
LQAGPARRRLGHAA

Specific function: Acts as a receptor for citrate and mediates taxis away from phenol. Also mediates an attractant response to metal-citrate complexes [H]

COG id: COG0840

COG function: function code NT; Methyl-accepting chemotaxis protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=299, Percent_Identity=59.1973244147157, Blast_Score=285, Evalue=7e-78,
Organism=Escherichia coli, GI1788195, Length=259, Percent_Identity=63.3204633204633, Blast_Score=278, Evalue=9e-76,
Organism=Escherichia coli, GI1787690, Length=290, Percent_Identity=55.5172413793103, Blast_Score=277, Evalue=2e-75,
Organism=Escherichia coli, GI1788194, Length=295, Percent_Identity=55.2542372881356, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1789453, Length=251, Percent_Identity=41.4342629482072, Blast_Score=195, Evalue=7e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 69924; Mature: 69924

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSTLIYSPETTESLTRLDAASDPSQAGDSRAMLREQLDQLARNHVRFRHELDKAMGLLE
CCCCEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QPDPALADAAKVEATQSRAALAALGTALEGSDAKADAQWNAALDALGQSMRDLSNVSLQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQRQSERHLVDARNAMWQAIAGLSVLALLIAALCWYTLSRLTRNVRRAATVAANIAQGQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DDQVSAAGRDETGQLLDTMRQMQGQLQRVLSAQSEMAQRHDAGQISYRMQADSFPGAYAT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
MVRDTNALVGSHIAVKMKLAQIMSRYAIGDLSQDMERLPGEKAVFTDTMDTVKANLSAMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHH
SEIKLLAQAAANGDFSVRGDAQRFQYDFRAMVDSLNQLMATSDANLHALSTVLQAIAAGD
HHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
LTARMHGDFHGVFARMRDDANTTVTQLANIVGRIQQSTNAINDAASEIATGNQDLSQRTE
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QQAANLEETAASMEELTSTVRNNAEHARRANQLVVGAATVASQGGAVVGEVVGTMAGIQA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEHHHHHCCCCHHHHHHHHHHHHHHH
ASKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLAQRSAGAAKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHH
IKQLIEDSVSRVEHGNQLVGQAGRTMQDIVDSVQNVTTIMHEISEASQQQSQGIEQVGQT
HHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAQMDQATQQNAALVEEATAAARSMEEQAQQLRDAVSVFQLQAGPARRRLGHAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
>Mature Secondary Structure
MVSTLIYSPETTESLTRLDAASDPSQAGDSRAMLREQLDQLARNHVRFRHELDKAMGLLE
CCCCEEECCCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
QPDPALADAAKVEATQSRAALAALGTALEGSDAKADAQWNAALDALGQSMRDLSNVSLQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LQRQSERHLVDARNAMWQAIAGLSVLALLIAALCWYTLSRLTRNVRRAATVAANIAQGQL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
DDQVSAAGRDETGQLLDTMRQMQGQLQRVLSAQSEMAQRHDAGQISYRMQADSFPGAYAT
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHH
MVRDTNALVGSHIAVKMKLAQIMSRYAIGDLSQDMERLPGEKAVFTDTMDTVKANLSAMN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHH
SEIKLLAQAAANGDFSVRGDAQRFQYDFRAMVDSLNQLMATSDANLHALSTVLQAIAAGD
HHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCC
LTARMHGDFHGVFARMRDDANTTVTQLANIVGRIQQSTNAINDAASEIATGNQDLSQRTE
HHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
QQAANLEETAASMEELTSTVRNNAEHARRANQLVVGAATVASQGGAVVGEVVGTMAGIQA
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHEEEHHHHHCCCCHHHHHHHHHHHHHHH
ASKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRTLAQRSAGAAKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCHHH
IKQLIEDSVSRVEHGNQLVGQAGRTMQDIVDSVQNVTTIMHEISEASQQQSQGIEQVGQT
HHHHHHHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IAQMDQATQQNAALVEEATAAARSMEEQAQQLRDAVSVFQLQAGPARRRLGHAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8419927; 11677609 [H]