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The map label for this gene is mtnD

Identifier: 21242583

GI number: 21242583

Start: 2134831

End: 2135397

Strand: Reverse

Name: mtnD

Synonym: XAC1839

Alternate gene names: 21242583

Gene position: 2135397-2134831 (Counterclockwise)

Preceding gene: 21242584

Following gene: 21242582

Centisome position: 41.26

GC content: 62.96

Gene sequence:

>567_bases
ATGAGCCGACTGCGTATCTTTGCCGACACCAATCCCGCCACACCCGAGTTCGATAGCCGCGACGGCGATGCGATCGCCGC
CGAGCTGGTCAAGATCGGCGTGACCTTCGAACGCTGGCATGCCAGCGCGCCGGTCGAACCGGGCGCAACGCCCGAGCAGG
TGATGGATGCCTACCGCGCCGATATCGACCGCATCAGTGCCGAGCGCGGCTTCAAGACCGTGGACGTGGTCAGCATCGCG
CCGGACAACCCCAAGCGCGAAGAAATGCGCGCCAAGTTTCTGGACGAACACTTCCACAAGGAAGACGAAGTGCGGTTTTT
CGTCGCCGGCTCGGGCCTGTTCACGCTGCACGTCGATGCCAAGGTTTACGAGATCGAATGCGTCAAGGACGACCTGATTG
CCGTGCCCGACGGCACCCTGCACTGGTTCGACATGGGACCGGAACCGCACTTCGTGGCGATCCGCTTCTTCACCGAGCCG
GACGGCTGGGTCGGGCACTTCACCGGCACCGAAATCGCCAAACAATTCCCCCGCTACGCCCCCAAGAAACCTCACAAGGC
CAGCTGA

Upstream 100 bases:

>100_bases
TGGAAGCGTTCGAATTCCTGCTGCATTGCGAACTCGAACTGCTGAAACTGCGCGGCACGCGCTGAGTAATGCCCGCCCCC
CCATTCGTAGCCAGACCGCC

Downstream 100 bases:

>100_bases
CGATGACACGACCGCAAGCGATCCTCACCGATATCGAAGGTACGACCAGCAGCATTTCGTTCGTCAAGGACGTCTTGTTC
CCGTATGCGCGCCGTGCAAT

Product: dioxygenase

Products: NA

Alternate protein names: 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; DHK-MTPene dioxygenase; Acireductone dioxygenase (Fe(2+)-requiring); ARD'; Fe-ARD; Acireductone dioxygenase (Ni(2+)-requiring); ARD; Ni-ARD

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MSRLRIFADTNPATPEFDSRDGDAIAAELVKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIA
PDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEP
DGWVGHFTGTEIAKQFPRYAPKKPHKAS

Sequences:

>Translated_188_residues
MSRLRIFADTNPATPEFDSRDGDAIAAELVKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIA
PDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEP
DGWVGHFTGTEIAKQFPRYAPKKPHKAS
>Mature_187_residues
SRLRIFADTNPATPEFDSRDGDAIAAELVKIGVTFERWHASAPVEPGATPEQVMDAYRADIDRISAERGFKTVDVVSIAP
DNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDAKVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEPD
GWVGHFTGTEIAKQFPRYAPKKPHKAS

Specific function: Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- me

COG id: COG1791

COG function: function code S; Uncharacterized conserved protein, contains double-stranded beta-helix domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acireductone dioxygenase (ARD) family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTND_XANAC (Q8PLG1)

Other databases:

- EMBL:   AE008923
- RefSeq:   NP_642165.1
- ProteinModelPortal:   Q8PLG1
- SMR:   Q8PLG1
- GeneID:   1155910
- GenomeReviews:   AE008923_GR
- KEGG:   xac:XAC1839
- NMPDR:   fig|190486.1.peg.1809
- HOGENOM:   HBG660685
- OMA:   LTHHDDI
- ProtClustDB:   CLSK446459
- BioCyc:   XAXO190486:XAC1839-MONOMER
- HAMAP:   MF_01682
- InterPro:   IPR004313
- InterPro:   IPR011051
- InterPro:   IPR014710
- Gene3D:   G3DSA:2.60.120.10
- PANTHER:   PTHR23418

Pfam domain/function: PF03079 ARD; SSF51182 RmlC_like_cupin

EC number: =1.13.11.54; =1.13.11.53

Molecular weight: Translated: 21230; Mature: 21099

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRLRIFADTNPATPEFDSRDGDAIAAELVKIGVTFERWHASAPVEPGATPEQVMDAYRA
CCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHH
DIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDA
HHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECC
KVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYA
EEEEEEEECCCEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHCC
PKKPHKAS
CCCCCCCC
>Mature Secondary Structure 
SRLRIFADTNPATPEFDSRDGDAIAAELVKIGVTFERWHASAPVEPGATPEQVMDAYRA
CCEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHCCCCCCCCCCCHHHHHHHHHH
DIDRISAERGFKTVDVVSIAPDNPKREEMRAKFLDEHFHKEDEVRFFVAGSGLFTLHVDA
HHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCEEEEEECC
KVYEIECVKDDLIAVPDGTLHWFDMGPEPHFVAIRFFTEPDGWVGHFTGTEIAKQFPRYA
EEEEEEEECCCEEECCCCCEEEEECCCCCCEEEEEEEECCCCCEEECCHHHHHHHHHHCC
PKKPHKAS
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217