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The map label for this gene is mtnB [H]

Identifier: 21242584

GI number: 21242584

Start: 2135433

End: 2136086

Strand: Reverse

Name: mtnB [H]

Synonym: XAC1840

Alternate gene names: 21242584

Gene position: 2136086-2135433 (Counterclockwise)

Preceding gene: 21242585

Following gene: 21242583

Centisome position: 41.27

GC content: 62.84

Gene sequence:

>654_bases
ATGAATGCGACCACTGCCCCCCTGCCCTATAGCGCCGCGCGTCTGCACGAGCTGGCGCATCTGCTGATCGCCAATATCCG
CGAGCTGGCCCATGCCGGCTGGACACCCGCGACCAGCAGCAATTTCTCCCACCGTCTGGACGAACAGCACGCGGCCATCA
CCGTCTCCGGCCGCGACAAGGGTCGCCTGGTCGAAGAAGACATCATGGTGGTGGACTTCGATGGCCTGGCCGTCGGCCGC
CCGTTGCGCCCGTCTGCCGAAACCCTGCTGCACACCCAGCTGTATCGCCGTTTCCCGGAGATCGGTTGCGTACTGCACAC
GCACTCGCCGATGCAGACGATTGCCTCCCGCCTGTATGCAGGCAGCGGCGTGATTCGGCTGGAAGGCTATGAACTGCTCA
AGGCCTTCGATGGCAACACCACCCACGAAACCGCGATGGAAGTGCCGGTGTTCGCCAATACCCAGGACATGCAGGTGCTG
GCCGCGCAGGTCGATGCCTTGCTGGACAAACAGAGCATGTGGGGGTATCTCATCGAAGGACACGGCCTGTATGCCTGGGG
CCGCAACATGGCCGAGGCACGTCGTCATCTGGAAGCGTTCGAATTCCTGCTGCATTGCGAACTCGAACTGCTGAAACTGC
GCGGCACGCGCTGA

Upstream 100 bases:

>100_bases
ACGGCCGCTGAGCCCACGCATGATCCGGCGTCGGGCGCGGCAGGACGACGCCTGCTGCGCTGCACCTGCCCATGCACCGG
GGGCGCAGTAGAATAGGTCC

Downstream 100 bases:

>100_bases
GTAATGCCCGCCCCCCCATTCGTAGCCAGACCGCCATGAGCCGACTGCGTATCTTTGCCGACACCAATCCCGCCACACCC
GAGTTCGATAGCCGCGACGG

Product: methylthioribulose-1-phosphate dehydratase

Products: NA

Alternate protein names: MTRu-1-P dehydratase [H]

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MNATTAPLPYSAARLHELAHLLIANIRELAHAGWTPATSSNFSHRLDEQHAAITVSGRDKGRLVEEDIMVVDFDGLAVGR
PLRPSAETLLHTQLYRRFPEIGCVLHTHSPMQTIASRLYAGSGVIRLEGYELLKAFDGNTTHETAMEVPVFANTQDMQVL
AAQVDALLDKQSMWGYLIEGHGLYAWGRNMAEARRHLEAFEFLLHCELELLKLRGTR

Sequences:

>Translated_217_residues
MNATTAPLPYSAARLHELAHLLIANIRELAHAGWTPATSSNFSHRLDEQHAAITVSGRDKGRLVEEDIMVVDFDGLAVGR
PLRPSAETLLHTQLYRRFPEIGCVLHTHSPMQTIASRLYAGSGVIRLEGYELLKAFDGNTTHETAMEVPVFANTQDMQVL
AAQVDALLDKQSMWGYLIEGHGLYAWGRNMAEARRHLEAFEFLLHCELELLKLRGTR
>Mature_217_residues
MNATTAPLPYSAARLHELAHLLIANIRELAHAGWTPATSSNFSHRLDEQHAAITVSGRDKGRLVEEDIMVVDFDGLAVGR
PLRPSAETLLHTQLYRRFPEIGCVLHTHSPMQTIASRLYAGSGVIRLEGYELLKAFDGNTTHETAMEVPVFANTQDMQVL
AAQVDALLDKQSMWGYLIEGHGLYAWGRNMAEARRHLEAFEFLLHCELELLKLRGTR

Specific function: Catalyzes the dehydration of methylthioribulose-1- phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1- phosphate (DK-MTP-1-P) [H]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. MtnB subfamily [H]

Homologues:

Organism=Drosophila melanogaster, GI18859685, Length=204, Percent_Identity=26.9607843137255, Blast_Score=70, Evalue=7e-13,

Paralogues:

None

Copy number: 136 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR017714 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.2.1.109 [H]

Molecular weight: Translated: 24267; Mature: 24267

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNATTAPLPYSAARLHELAHLLIANIRELAHAGWTPATSSNFSHRLDEQHAAITVSGRDK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEEECCCCC
GRLVEEDIMVVDFDGLAVGRPLRPSAETLLHTQLYRRFPEIGCVLHTHSPMQTIASRLYA
CCEECCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHCCHHCEEEECCCHHHHHHHHHHC
GSGVIRLEGYELLKAFDGNTTHETAMEVPVFANTQDMQVLAAQVDALLDKQSMWGYLIEG
CCCEEEECHHHHHHHHCCCCCCHHHEECCEECCCHHHHHHHHHHHHHHHHHHHCEEEEEC
HGLYAWGRNMAEARRHLEAFEFLLHCELELLKLRGTR
CEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNATTAPLPYSAARLHELAHLLIANIRELAHAGWTPATSSNFSHRLDEQHAAITVSGRDK
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCEEEEECCCCC
GRLVEEDIMVVDFDGLAVGRPLRPSAETLLHTQLYRRFPEIGCVLHTHSPMQTIASRLYA
CCEECCCEEEEEECCEECCCCCCCHHHHHHHHHHHHHCCHHCEEEECCCHHHHHHHHHHC
GSGVIRLEGYELLKAFDGNTTHETAMEVPVFANTQDMQVLAAQVDALLDKQSMWGYLIEG
CCCEEEECHHHHHHHHCCCCCCHHHEECCEECCCHHHHHHHHHHHHHHHHHHHCEEEEEC
HGLYAWGRNMAEARRHLEAFEFLLHCELELLKLRGTR
CEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA