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The map label for this gene is gbpR [H]

Identifier: 21242513

GI number: 21242513

Start: 2023515

End: 2024486

Strand: Direct

Name: gbpR [H]

Synonym: XAC1767

Alternate gene names: 21242513

Gene position: 2023515-2024486 (Clockwise)

Preceding gene: 21242507

Following gene: 21242514

Centisome position: 39.1

GC content: 66.46

Gene sequence:

>972_bases
ATGGCAAATTCCGGTACTCCCTGGTTCAACGCAGCCCGGCTCAAGACGCGCCAGCTCCTGCTGCTGCTGCATTTGCACGA
ACAGCGCTCGGTGTTGCGCGCGGCTGAGGCCGCTAGCATGACGCAACCGGCCGCGTCCAAGTTGCTGGCGGAAATGGAAG
ACATGCTGGGGGTGAAATTATTCGAGCGGCATGCCCGTGGCGTGGAGCCCACCTGGTATGGCCACGTGCTGATCCGGCGC
GCACGCGCAGCGATGTCGGAGATTGGGCGGGCGCAGGAAGAAATCGCCGCGCTGCGCGCCGGCCGCATGGGCCAGGCTTC
GATCGGCACGGTGGTCAATCCGGGCACCAACCTGGTGCCGCAGGCCATCGCCGAGGTCAAGCGCGAATTTCCGGACATCC
TGGTGCGGGTGGAAATGGACTACAGCCGTCCGCTGGTGGCCAAGTTGCTGGACGGGCAGCTCGATATCGTGATCGGGCGC
ATCCTCGGGCCGGAAGGGGTGGGCGAGCTGGAGTTCGAGCCGCTGGCCGACGAGCCGCATTCGGTGATCGCGCGTGCCGG
CCATCCGCTGGCCAGCCGCGCCGGCCTGCAGCACGCCGATCTGGTACGGCACGGCTGGATTCTGCCGCCGGCCGACAGCG
TGTTGCGCGCGCGCCTGGATTCGATGTTCATGGAGCACGGCGTGCAGACGCCGACCAATGCCATCGAAACCTCATCGCTG
CCGGTCACCTCGACCCTGCTGCGCGGCACCGACATGCTGACCGCCCTGCCGGTGGAATCGGTGGCGCCGTTGATCCAGGC
GAAATTGCTTACCGTGCTGCCGATCGAACTGGGCGTGCGGATGGAATCGTTCGGCATCATCCGTCGACGCGATTACGTCC
TGCCGCCCGGTGCCGAGCGCATTTTGCAGGCGTTGCGCACCACTGCACGACGTCTGTATCCCGCGCTGCGCGTGCCGGAC
TCCCTTGCCTGA

Upstream 100 bases:

>100_bases
CTGCGGCGTTCGATAGCCTCGCGCGGGGAGATATGTGCTGCAAATGAAATTTTCGGCATATTCTATTCCTCCGACGAATA
CACGGTCGCAACCGCACGCT

Downstream 100 bases:

>100_bases
CCAGTGCGCTCATCGCTATTCCGCAGTGGAATAGCAGCCTGTGAAATTTTCATTGGCTGGCGCTGCGTGGTGCGCCTATA
CGTGTGAACCAAATCGCACG

Product: galactose-binding protein regulator

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 323; Mature: 322

Protein sequence:

>323_residues
MANSGTPWFNAARLKTRQLLLLLHLHEQRSVLRAAEAASMTQPAASKLLAEMEDMLGVKLFERHARGVEPTWYGHVLIRR
ARAAMSEIGRAQEEIAALRAGRMGQASIGTVVNPGTNLVPQAIAEVKREFPDILVRVEMDYSRPLVAKLLDGQLDIVIGR
ILGPEGVGELEFEPLADEPHSVIARAGHPLASRAGLQHADLVRHGWILPPADSVLRARLDSMFMEHGVQTPTNAIETSSL
PVTSTLLRGTDMLTALPVESVAPLIQAKLLTVLPIELGVRMESFGIIRRRDYVLPPGAERILQALRTTARRLYPALRVPD
SLA

Sequences:

>Translated_323_residues
MANSGTPWFNAARLKTRQLLLLLHLHEQRSVLRAAEAASMTQPAASKLLAEMEDMLGVKLFERHARGVEPTWYGHVLIRR
ARAAMSEIGRAQEEIAALRAGRMGQASIGTVVNPGTNLVPQAIAEVKREFPDILVRVEMDYSRPLVAKLLDGQLDIVIGR
ILGPEGVGELEFEPLADEPHSVIARAGHPLASRAGLQHADLVRHGWILPPADSVLRARLDSMFMEHGVQTPTNAIETSSL
PVTSTLLRGTDMLTALPVESVAPLIQAKLLTVLPIELGVRMESFGIIRRRDYVLPPGAERILQALRTTARRLYPALRVPD
SLA
>Mature_322_residues
ANSGTPWFNAARLKTRQLLLLLHLHEQRSVLRAAEAASMTQPAASKLLAEMEDMLGVKLFERHARGVEPTWYGHVLIRRA
RAAMSEIGRAQEEIAALRAGRMGQASIGTVVNPGTNLVPQAIAEVKREFPDILVRVEMDYSRPLVAKLLDGQLDIVIGRI
LGPEGVGELEFEPLADEPHSVIARAGHPLASRAGLQHADLVRHGWILPPADSVLRARLDSMFMEHGVQTPTNAIETSSLP
VTSTLLRGTDMLTALPVESVAPLIQAKLLTVLPIELGVRMESFGIIRRRDYVLPPGAERILQALRTTARRLYPALRVPDS
LA

Specific function: Does not seem to be required for sbpA expression [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=282, Percent_Identity=26.241134751773, Blast_Score=104, Evalue=7e-24,
Organism=Escherichia coli, GI87081904, Length=298, Percent_Identity=24.496644295302, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789506, Length=289, Percent_Identity=23.1833910034602, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1790399, Length=294, Percent_Identity=27.891156462585, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI145693105, Length=281, Percent_Identity=25.9786476868327, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI157672245, Length=245, Percent_Identity=27.7551020408163, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1788748, Length=313, Percent_Identity=26.1980830670927, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788297, Length=213, Percent_Identity=27.6995305164319, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1788887, Length=192, Percent_Identity=28.125, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1789204, Length=202, Percent_Identity=28.2178217821782, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35389; Mature: 35258

Theoretical pI: Translated: 9.50; Mature: 9.50

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANSGTPWFNAARLKTRQLLLLLHLHEQRSVLRAAEAASMTQPAASKLLAEMEDMLGVKL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FERHARGVEPTWYGHVLIRRARAAMSEIGRAQEEIAALRAGRMGQASIGTVVNPGTNLVP
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHH
QAIAEVKREFPDILVRVEMDYSRPLVAKLLDGQLDIVIGRILGPEGVGELEFEPLADEPH
HHHHHHHHHHHHEEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCHH
SVIARAGHPLASRAGLQHADLVRHGWILPPADSVLRARLDSMFMEHGVQTPTNAIETSSL
HHHHHCCCCHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
PVTSTLLRGTDMLTALPVESVAPLIQAKLLTVLPIELGVRMESFGIIRRRDYVLPPGAER
CHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHH
ILQALRTTARRLYPALRVPDSLA
HHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ANSGTPWFNAARLKTRQLLLLLHLHEQRSVLRAAEAASMTQPAASKLLAEMEDMLGVKL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
FERHARGVEPTWYGHVLIRRARAAMSEIGRAQEEIAALRAGRMGQASIGTVVNPGTNLVP
HHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCCHHH
QAIAEVKREFPDILVRVEMDYSRPLVAKLLDGQLDIVIGRILGPEGVGELEFEPLADEPH
HHHHHHHHHHHHEEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCHH
SVIARAGHPLASRAGLQHADLVRHGWILPPADSVLRARLDSMFMEHGVQTPTNAIETSSL
HHHHHCCCCHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCCCCC
PVTSTLLRGTDMLTALPVESVAPLIQAKLLTVLPIELGVRMESFGIIRRRDYVLPPGAER
CHHHHHHHCCHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCHHH
ILQALRTTARRLYPALRVPDSLA
HHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]